PROSITE documentation PDOC00050

Ribosomal protein L39e signature

Description:

A number of eukaryotic and archaebacterial ribosomal proteins can be grouped on the basis of sequence similarities. One of these families consists of:

  • Mammalian L39 [1].
  • Plants L39.
  • Yeast L46 [2].
  • Archebacterial L39e [3].

These proteins are very basic. About 50 residues long, they are the smallest proteins of eukaryotic-type ribosomes. As a signature pattern, we selected a conserved region in the C-terminal section of these proteins.

Last update:

December 2004 / Pattern and text revised.

Technical section:

PROSITE method (with tools and information) covered by this documentation:

RIBOSOMAL_L39E, PS00051Ribosomal protein L39e signature  (PATTERN)
Consensus pattern: [KRM]-[PTKS]-x(3)-[LIVMFG]-x(2)-[NHS]-x(3)-R-[DNHY]-W-R-[RS]
Sequences known to belong to this class detected by the pattern: ALL
Other sequence(s) detected in Swiss-Prot: NONE
• Retrieve an alignment of Swiss-Prot true positive hits:
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Scan Swiss-Prot/TrEMBL entries against PS00051
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Matching PDB structures: 1YJ9 3IZS 3O58 3O5H ... [ALL]

References:

1 AuthorsLin A., McNally J., Wool I.G.
TitleThe primary structure of rat liver ribosomal protein L39.
SourceJ. Biol. Chem. 259:487-490(1984).
PubMed ID6706949
2 AuthorsLeer R.J., van Raamsdonk-Duin M.M.C., Kraakman P., Mager W.H., Planta R.J.
TitleThe genes for yeast ribosomal proteins S24 and L46 are adjacent and divergently transcribed.
SourceNucleic Acids Res. 13:701-709(1985).
PubMed ID4000930
3 AuthorsRamirez C., Louie K.A., Matheson A.T.
TitleA small basic ribosomal protein in Sulfolobus solfataricus equivalent to L46 in yeast: structure of the protein and its gene.
SourceFEBS Lett. 250:416-418(1989).
PubMed ID2502431

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