{PDOC00051} {PS00052; RIBOSOMAL_S7} {BEGIN} ********************************** * Ribosomal protein S7 signature * ********************************** Ribosomal protein S7 is one of the proteins from the small ribosomal subunit. In Escherichia coli, S7 is known to bind directly to part of the 3'end of 16S ribosomal RNA. It belongs to a family of ribosomal proteins which, on the basis of sequence similarities [1,2,3], groups: - Eubacterial S7. - Algal and plant chloroplast S7. - Cyanelle S7. - Archaebacterial S7. - Plant mitochondrial S7. - Mammalian S5. - Plant S5. - Caenorhabditis elegans S5 (T05E11.1). As a signature pattern, we selected the best conserved region located in the N-terminal section of these proteins. -Consensus pattern: [DENSK]-x-[LIVMDET]-x(3)-[LIVMFTA](2)-x(6)-G-K-[KR]-x(5)- [LIVMF]-[LIVMFC]-x(2)-[STAC] -Sequences known to belong to this class detected by the pattern: ALL, except for Thermococcus celer S7 and Acanthamoeba castellanii mitochondrial S7. -Other sequence(s) detected in Swiss-Prot: NONE. -Last update: July 1999 / Pattern and text revised. [ 1] Klussmann S., Franke P., Bergmann U., Kostka S., Wittmann-Liebold B. "N-terminal modification and amino-acid sequence of the ribosomal protein HmaS7 from Haloarcula marismortui and homology studies to other ribosomal proteins." Biol. Chem. Hoppe-Seyler 374:305-312(1993). PubMed=8338632 [ 2] Otaka E., Hashimoto T., Mizuta K. Protein Seq. Data Anal. 5:285-300(1993). [ 3] Ignatovich O., Cooper M., Kulesza H.M., Beggs J.D. "Cloning and characterisation of the gene encoding the ribosomal protein S5 (also known as rp14, S2, YS8) of Saccharomyces cerevisiae." Nucleic Acids Res. 23:4616-4619(1995). PubMed=8524651 -------------------------------------------------------------------------------- PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see https://prosite.expasy.org/prosite_license.html -------------------------------------------------------------------------------- {END}