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PROSITE documentation PDOC00052

Ribosomal protein S8 signature

Description:

Ribosomal protein S8 is one of the proteins from the small ribosomal subunit. In Escherichia coli, S8 is known to bind directly to 16S ribosomal RNA. It belongs to a family of ribosomal proteins which, on the basis of sequence similarities [1], groups:

  • Eubacterial S8.
  • Algal and plant chloroplast S8.
  • Cyanelle S8.
  • Archaebacterial S8.
  • Marchantia polymorpha mitochondrial S8.
  • Mammalian S15A.
  • Plant S15A.
  • Yeast S22 (S24).

As a signature pattern, we selected the best conserved region located in the C-terminal section of these proteins.

Last update:

April 2006 / Pattern revised.

Technical section:

PROSITE method (with tools and information) covered by this documentation:

RIBOSOMAL_S8, PS00053; Ribosomal protein S8 signature  (PATTERN)
Consensus pattern: [GE]-x(2)-[LIV](2)-[STY]-[ST]-{A}-x-G-[LIVM](2)-x(4)-[AG]-[KRHAYIL]
Sequences known to belong to this class detected by the pattern: ALL, except for some mitochondrial S8
Other sequence(s) detected in Swiss-Prot: 1
• Retrieve an alignment of Swiss-Prot true positive hits:
  Clustal format, color, condensed view  / Clustal format, color  / Clustal format, plain text  / Fasta format
• Retrieve the sequence logo from the alignment
• Taxonomic tree view of all Swiss-Prot/TrEMBL entries matching PS00053
• Retrieve a list of all Swiss-Prot/TrEMBL entries matching PS00053
• Scan Swiss-Prot/TrEMBL entries against PS00053
• view ligand binding statistics
Matching PDB structures: 1AN7 1EG0 1EMI 1FJG ... [ALL]

Reference:

1 AuthorsOtaka E., Hashimoto T., Mizuta K.
SourceProtein Seq. Data Anal. 5:285-300(1993).

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