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| PROSITE documentation PDOC00310 |
Ribosomal protein L11 signature
Description:
Ribosomal protein L11 is one of the proteins from the large ribosomal subunit.
In Escherichia coli, L11 is known to bind directly to the 23S rRNA. It belongs
to a family of ribosomal proteins which, on the basis of sequence similarities
[1,2], groups:
- Eubacterial L11.
- Plant chloroplast L11 (nuclear-encoded).
- Read algal chloroplast L11.
- Cyanelle L11.
- Archaebacterial L11.
- Mammalian L12.
- Plants L12.
- Yeast L12 (YL15).
L11 is a protein of 140 to 165 amino-acid residues. As a signature pattern, we
have selected a conserved region located in the C-terminal section of these
proteins. In Escherichia coli, the C-terminal half of L11 has been shown [3]
to be in an extended and loosely folded conformation and is likely to be
buried within the ribosomal structure.
Last update:
April 2006 / Pattern revised.
Technical section:
PROSITE method (with tools and information) covered by this documentation:
| RIBOSOMAL_L11, PS00359; Ribosomal protein L11 signature (PATTERN) |
| Consensus pattern: |
[RKN]-x-[LIVM]-x-G-[ST]-x(2)-[SNQ]-[LIVM]-G-x-{M}-[LIVM]-x(0,1)-[DENG]
|
| Sequences known to belong to this class detected by the pattern: |
ALL |
| Other sequence(s) detected in Swiss-Prot: |
2 |
|
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| Matching PDB structures:
1ACI 1FOW 1FOX 1FOY ... [ALL] |
References:
| 1 |
Authors | Pucciarelli M.G., Remacha M., Vilella M.D., Ballesta J.P.G. |
| Title | The 26S rRNA binding ribosomal protein equivalent to bacterial protein L11 is encoded by unspliced duplicated genes in Saccharomyces cerevisiae. |
| Source | Nucleic Acids Res. 18:4409-4416(1990). |
| PubMed ID | 2167467 |
| 2 |
Authors | Otaka E., Hashimoto T., Mizuta K., Suzuki K. |
| Source | Protein Seq. Data Anal. 5:301-313(1993). |
| 3 |
Authors | Choli T. |
| Title | Structural properties of ribosomal protein L11 from Escherichia coli. |
| Source | Biochem. Int. 19:1323-1338(1989). |
| PubMed ID | 2483975 |
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