{PDOC00346} {PS00418; POTEX_CARLAVIRUS_COAT} {BEGIN} ******************************************************** * Potexviruses and carlaviruses coat protein signature * ******************************************************** Potexviruses and carlaviruses are plant-infecting viruses whose genome consist of a single-stranded RNA molecule encapsided in a coat protein. The genome of many potexviruses is known and their coat protein sequence has been shown to be rather well conserved [1]. The same observation applies to the coat protein of a variety of carlaviruses whose sequences are related to those of potexviruses [2,3]. The coat proteins of potexviruses and of carlaviruses contain from 190 to 300 amino acid residues. The best conserved region of these coat proteins is located in the central part and can be used as a signature pattern. -Consensus pattern: [RK]-[FYW]-A-[GAP]-F-D-x-F-x(2)-[LV]-x(3)-[GASTY]-[GASTV] -Sequences known to belong to this class detected by the pattern: ALL, except for the coat protein of Foxtail Mosaic Virus (FMV). -Other sequence(s) detected in Swiss-Prot: NONE. -Last update: December 2004 / Pattern and text revised. [ 1] Abouhaidar M.G., Lai R. "Nucleotide sequence of the 3'-terminal region of clover yellow mosaic virus RNA." J. Gen. Virol. 70:1871-1875(1989). PubMed=2738582 [ 2] MacKenzie D.J., Tremaine J.H., Stace-Smith R. "Organization and interviral homologies of the 3'-terminal portion of potato virus S RNA." J. Gen. Virol. 70:1053-1063(1989). PubMed=2732711 [ 3] Henderson J., Gibbs M.J., Edwards M.L., Clarke V.A., Gardner K.A., Cooper J.I. "Partial nucleotide sequence of poplar mosaic virus RNA confirms its classification as a carlavirus." J. Gen. Virol. 73:1887-1890(1992). PubMed=1629709 -------------------------------------------------------------------------------- PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see https://prosite.expasy.org/prosite_license.html -------------------------------------------------------------------------------- {END}