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PROSITE documentation PDOC00387

Ribosomal protein L22 signature

Description:

Ribosomal protein L22 is one of the proteins from the large ribosomal subunit. In Escherichia coli, L22 is known to bind 23S rRNA. It belongs to a family of ribosomal proteins which, on the basis of sequence similarities [1,2,3], groups:

  • Eubacterial L22.
  • Algal and plant chloroplast L22 (in legumes L22 is encoded in the nucleus instead of the chloroplast).
  • Cyanelle L22.
  • Archaebacterial L22.
  • Mammalian L17.
  • Plant L17.
  • Yeast YL17.

As a signature pattern, we selected a conserved region located in the C-terminal section of these proteins.

Last update:

April 2006 / Pattern revised.

Technical section:

PROSITE method (with tools and information) covered by this documentation:

RIBOSOMAL_L22, PS00464; Ribosomal protein L22 signature  (PATTERN)
Consensus pattern: [RKQN]-x(2)-{G}-x-[RH]-[GAS]-x-G-[KRQS]-x(8)-{L}-[HDN]-[LIVM]-{A}-[LIVMS]-x-[LIVM]
Sequences known to belong to this class detected by the pattern: ALL
Other sequence(s) detected in Swiss-Prot: 7
• Retrieve an alignment of Swiss-Prot true positive hits:
  Clustal format, color, condensed view  / Clustal format, color  / Clustal format, plain text  / Fasta format
• Retrieve the sequence logo from the alignment
• Taxonomic tree view of all Swiss-Prot/TrEMBL entries matching PS00464
• Retrieve a list of all Swiss-Prot/TrEMBL entries matching PS00464
• Scan Swiss-Prot/TrEMBL entries against PS00464
• view ligand binding statistics
Matching PDB structures: 1BXE 1FFK 1GIY 1J5A ... [ALL]

References:

1 AuthorsGantt J.S., Baldauf S.L., Calie P.J., Weeden N.F., Palmer J.D.
TitleTransfer of rpl22 to the nucleus greatly preceded its loss from the chloroplast and involved the gain of an intron.
SourceEMBO J. 10:3073-3078(1991).
PubMed ID1915281
2 AuthorsMadsen L.H., Kreiberg J.D., Gausing K.
TitleA small gene family in barley encodes ribosomal proteins homologous to yeast YL17 and L22 from archaebacteria, eubacteria, and chloroplasts.
SourceCurr. Genet. 19:417-422(1991).
PubMed ID1913880
3 AuthorsOtaka E., Hashimoto T., Mizuta K., Suzuki K.
SourceProtein Seq. Data Anal. 5:301-313(1993).

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