PROSITE documentation PDOC00408

FGGY family of carbohydrate kinases signatures




Description

It has been shown [1] that four different type of carbohydrate kinases seem to be evolutionary related. These enzymes are:

  • L-fuculokinase (EC 2.7.1.51) (gene fucK).
  • Gluconokinase (EC 2.7.1.12) (gene gntK).
  • Glycerokinase (EC 2.7.1.30) (gene glpK).
  • Xylulokinase (EC 2.7.1.17) (gene xylB).
  • L-xylulose kinase (EC 2.7.1.53) (gene lyxK).

These enzymes are proteins of from 480 to 520 amino acid residues.

As consensus patterns for this family of kinases we selected two conserved regions, one in the central section, the other in the C-terminal section.

Last update:

April 2006 / Pattern revised.

Technical section

PROSITE methods (with tools and information) covered by this documentation:

FGGY_KINASES_1, PS00933; FGGY family of carbohydrate kinases signature 1  (PATTERN)

FGGY_KINASES_2, PS00445; FGGY family of carbohydrate kinases signature 2  (PATTERN)


Reference

1AuthorsReizer A., Deutscher J., Saier M.H. Jr., Reizer J.
TitleAnalysis of the gluconate (gnt) operon of Bacillus subtilis.
SourceMol. Microbiol. 5:1081-1089(1991).
PubMed ID1659648



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