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PROSITE documentation PDOC00456

Ribosomal protein S14 signature

Description:

Ribosomal protein S14 is one of the proteins from the small ribosomal subunit. In Escherichia coli, S14 is known to be required for the assembly of 30S particles and may also be responsible for determining the conformation of 16S rRNA at the A site. It belongs to a family of ribosomal proteins which, on the basis of sequence similarities [1,2], groups:

  • Eubacterial S14.
  • Algal and plant chloroplast S14.
  • Cyanelle S14.
  • Archaebacterial Methanococcus vannielii S14.
  • Plant mitochondrial S14.
  • Yeast mitochondrial MRP2.
  • Mammalian S29.
  • Yeast YS29A/B.

S14 is a protein of 53 to 115 amino-acid residues. Our signature pattern is based on the few conserved positions located in the center of these proteins.

Last update:

April 2006 / Pattern revised.

Technical section:

PROSITE method (with tools and information) covered by this documentation:

RIBOSOMAL_S14, PS00527; Ribosomal protein S14 signature  (PATTERN)
Consensus pattern: [RP]-x(0,1)-C-x(11,12)-[LIVMF]-{L}-[LIVMF]-[SC]-[RG]-x-{D}-{PK}-[RN]
Sequences known to belong to this class detected by the pattern: ALL
Other sequence(s) detected in Swiss-Prot: 16
• Retrieve an alignment of Swiss-Prot true positive hits:
  Clustal format, color, condensed view  / Clustal format, color  / Clustal format, plain text  / Fasta format
• Retrieve the sequence logo from the alignment
• Taxonomic tree view of all Swiss-Prot/TrEMBL entries matching PS00527
• Retrieve a list of all Swiss-Prot/TrEMBL entries matching PS00527
• Scan Swiss-Prot/TrEMBL entries against PS00527
• view ligand binding statistics
Matching PDB structures: 1FJG 1GIX 1HNW 1HNX ... [ALL]

References:

1 AuthorsChan Y.-L., Suzuki K., Olvera J., Wool I.G.
TitleZinc finger-like motifs in rat ribosomal proteins S27 and S29.
SourceNucleic Acids Res. 21:649-655(1993).
PubMed ID8441676
2 AuthorsOtaka E., Hashimoto T., Mizuta K.
SourceProtein Seq. Data Anal. 5:285-300(1993).

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