{PDOC00474} {PS00548; RIBOSOMAL_S3} {BEGIN} ********************************** * Ribosomal protein S3 signature * ********************************** Ribosomal protein S3 is one of the proteins from the small ribosomal subunit. In Escherichia coli, S3 is known to be involved in the binding of initiator Met-tRNA. It belongs to a family of ribosomal proteins which, on the basis of sequence similarities [1], groups: - Eubacterial S3. - Algal and plant chloroplast S3. - Cyanelle S3. - Archaebacterial S3. - Plant mitochondrial S3. - Vertebrate S3. - Insect S3. - Caenorhabditis elegans S3 (C23G10.3). - Yeast S3 (Rp13). S3 is a protein of 209 to 559 amino-acid residues. As signature patterns, we selected a conserved region located in the C-terminal section. -Consensus pattern: [GSTA]-[KR]-x(6)-G-x-[LIVMT]-x(2)-[NQSCH]-x(1,3)-[LIVFCA]- x(3)-[LIV]-[DENQ]-x(7)-[LMT]-x(2)-G-x(2)-[GS] -Sequences known to belong to this class detected by the pattern: ALL, except for some mitochondrial S3. -Other sequence(s) detected in Swiss-Prot: NONE. -Expert(s) to contact by email: Hallick R.B.; hallick@arizona.edu -Last update: December 2001 / Pattern and text revised. [ 1] Otaka E., Hashimoto T., Mizuta K. Protein Seq. Data Anal. 5:285-300(1993). -------------------------------------------------------------------------------- PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see https://prosite.expasy.org/prosite_license.html -------------------------------------------------------------------------------- {END}