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PROSITE documentation PDOC00506

Ribosomal protein L16 signatures

Description:

Ribosomal protein L16 is one of the proteins from the large ribosomal subunit. In Escherichia coli, L16 is known to bind directly the 23S rRNA and to be located at the A site of the peptidyltransferase center. It belongs to a family of ribosomal proteins which, on the basis of sequence similarities [1], groups:

  • Eubacterial L16.
  • Algal and plant chloroplast L16.
  • Cyanelle L16.
  • Plant mitochondrial L16.

L16 is a protein of 133 to 185 amino-acid residues. As signature patterns, we selected two conserved regions in the central section of these proteins.

Last update:

December 2004 / Pattern and text revised.

Technical section:

PROSITE methods (with tools and information) covered by this documentation:

RIBOSOMAL_L16_1, PS00586; Ribosomal protein L16 signature 1  (PATTERN)
Consensus pattern: [KRG]-[KR]-x-[GSAC]-[KRQVA]-[LIVMK]-[WY]-[LIVM]-[KRN]-[LIVM]-[LFY]-[APK]
Sequences known to belong to this class detected by the pattern: ALL
Other sequence(s) detected in Swiss-Prot: NONE.
• Retrieve an alignment of Swiss-Prot true positive hits:
  Clustal format, color, condensed view  / Clustal format, color  / Clustal format, plain text  / Fasta format
• Retrieve the sequence logo from the alignment
• Taxonomic tree view of all Swiss-Prot/TrEMBL entries matching PS00586
• Retrieve a list of all Swiss-Prot/TrEMBL entries matching PS00586
• Scan Swiss-Prot/TrEMBL entries against PS00586
• view ligand binding statistics
Matching PDB structures: 1GS2 1NJM 1NJP 1NKW ... [ALL]
RIBOSOMAL_L16_2, PS00701; Ribosomal protein L16 signature 2  (PATTERN)
Consensus pattern: R-M-G-x-[GR]-K-G-x(4)-[FWKR]
Sequences known to belong to this class detected by the pattern: ALL
Other sequence(s) detected in Swiss-Prot: NONE.
• Retrieve an alignment of Swiss-Prot true positive hits:
  Clustal format, color, condensed view  / Clustal format, color  / Clustal format, plain text  / Fasta format
• Retrieve the sequence logo from the alignment
• Taxonomic tree view of all Swiss-Prot/TrEMBL entries matching PS00701
• Retrieve a list of all Swiss-Prot/TrEMBL entries matching PS00701
• Scan Swiss-Prot/TrEMBL entries against PS00701
• view ligand binding statistics
Matching PDB structures: 1GS2 1NJM 1NJP 1NKW ... [ALL]

Reference:

1 AuthorsOtaka E., Hashimoto T., Mizuta K., Suzuki K.
SourceProtein Seq. Data Anal. 5:301-313(1993).

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