{PDOC00508}
{PS00588; FLAGELLA_BB_ROD}
{BEGIN}
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* Flagella basal body rod proteins signature *
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Many bacterial species  swim  actively by means of flagella [1].  The flagella
organelle is made of three parts:  the basal body, the hook  and the filament.
The basal body consists of four rings (L,P,S, and M) mounted on a central rod.
In Salmonella typhimurium and related organisms the  rod has been shown [2] to
consist of  four different, yet evolutionary related proteins:  in  the distal
portion of the  rod  there  are  about  26 subunits of protein flgG and in the
proximal portion  there  are about 6 subunits each of proteins flgB, flgC, and
flgF.

These four proteins  contain  in  their N-terminal section  a highly conserved
asparagine-rich domain that we have used as a signature pattern.

This pattern is also found in:

 - Flagella hook protein flgE from Gram-negative bacteria.
 - Flagellar  hook-associated  protein  1  (HAP1)  (flgK)  from  Gram-negative
   bacteria.
 - Flagellar hook-basal body proteins flhO and flhP from Bacillus subtilis.
 - The  central  section  of  the  flagella  core  protein  (flaA) of Borrelia
   burgdorferi.

-Consensus pattern: [GTARYQ]-x-{R}-x(7)-[LIVMYSTA](2)-[GSTA]-[STADEN]-N-
                    [LIVM]-[SAN]-N-x-[SADENFR]-[STV]
-Sequences known to belong to this class detected by the pattern: ALL,  except
 for 3 sequences.
-Other sequence(s) detected in Swiss-Prot: 2.
-Last update: December 2004 / Pattern and text revised.

[ 1] MacNab R.M.
     (In) Escherichia coli and Salmonella typhimurium: cellular and molecular
     biology, Neidhardt F.C., Ingraham J.L., Low K.B., Magasanik B.,
     Schaechter M., Umbarger H.E., Eds., pp70-83, American society for
     Microbiology, Washington D.C, (1987).
[ 2] Homma M., Kutsukake K., Hasebe M., Iino T., Macnab R.M.
     "FlgB, FlgC, FlgF and FlgG. A family of structurally related proteins
     in the flagellar basal body of Salmonella typhimurium."
     J. Mol. Biol. 211:465-477(1990).
     PubMed=2129540

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