PROSITE documentation PDOC00551

Ribosomal protein L30 signature

Description:

Ribosomal protein L30 is one of the proteins from the large ribosomal subunit. L30 belongs to a family of ribosomal proteins which, on the basis of sequence similarities [1], groups:

  • Eubacterial L30.
  • Archaebacterial L30.
  • Drosophila L7.
  • Slime mold L7.
  • Mammalian L7.
  • Fungi L7 (YL8).
  • Yeast mitochondrial L33.

L30 from eubacteria are small proteins of about 60 residues, those from archaebacteria are proteins of about 150 residues. Eukaryotic L7 are proteins of about 250 to 270 residues. The schematic relationship between the three groups of proteins is shown below.

 Eub. L30                         NxxxxxxxxxxC
 Arc. L30                         NxxxxxxxxxxxxxxxxxxxxxxxxxxxC
 Euk. L7      NxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxC
                                   *******
'*': position of the pattern.

The signature pattern for this family of ribosomal proteins spans the N-terminal half of the region common to all these proteins.

Last update:

December 2004 / Pattern and text revised.

Technical section:

PROSITE method (with tools and information) covered by this documentation:

RIBOSOMAL_L30, PS00634Ribosomal protein L30 signature  (PATTERN)
Consensus pattern: [IVTAS]-[LIVM]-x(2)-[LF]-x-[LI]-x-[KRHQEG]-x(2)-[STNQH]-x-[IVTR]-x(10)-[LMSN]-[LIV]-x(2)-[LIVA]-x(2)-[LMFY]-[IVT]
Sequences known to belong to this class detected by the pattern: ALL
Other sequence(s) detected in Swiss-Prot: NONE
• Retrieve an alignment of Swiss-Prot true positive hits:
  Clustal format, color, condensed view  / Clustal format, color  / Clustal format, plain text  / Fasta format
Retrieve the sequence logo from the alignment
Taxonomic tree view of all Swiss-Prot/TrEMBL entries matching PS00634
Retrieve a list of all Swiss-Prot/TrEMBL entries matching PS00634
Scan Swiss-Prot/TrEMBL entries against PS00634
view ligand binding statistics
Matching PDB structures: 1BXY 1FFK 1GIY 1JJ2 ... [ALL]

Reference:

1 AuthorsMizuta K., Hashimoto T., Otaka E.
TitleYeast ribosomal proteins: XIII. Saccharomyces cerevisiae YL8A gene, interrupted with two introns, encodes a homolog of mammalian L7.
SourceNucleic Acids Res. 20:1011-1016(1992).
PubMed ID1549461

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