{PDOC00718}
{PS00929; PIR_REPEAT_1}
{PS50256; PIR_REPEAT_2}
{BEGIN}
****************************************************
* Yeast PIR proteins repeats signature and profile *
****************************************************

A number of yeast cell wall glycoproteins are characterized by the presence of
tandem repeats of a region of 18 to 19 residues [1,2,3]. These proteins are:

 - CCW7 (9 repeats).
 - CCW11 (1 repeat).
 - CWP2 or LPR1.
 - PIR1 or CCW6 (8 repeats).
 - PIR2 or HSP150 (11 repeats).
 - PIR3 or CCW8 (10 repeats).
 - TIR1 or SRP1 (1 repeat) (see <PDOC00596>).
 - TIR2 or SRP2 (1 repeat) (see <PDOC00596>).
 - Hypothetical protein YHR126c (1 repeat).
 - Hypothetical protein YJL160c (4 repeats).

The core  region  of  the  repeat  is  highly  conserved and is used here as a
signature pattern. We also developed a profile that spans the complete repeat.

-Consensus pattern: S-Q-[IV]-[STGNH]-D-G-Q-[LIV]-Q-[AIV]-[STA]
-Sequences known to belong to this class detected by the pattern: ALL.
-Other sequence(s) detected in Swiss-Prot: NONE.

-Sequences known to belong to this class detected by the profile: ALL.
-Other sequence(s) detected in Swiss-Prot: NONE.

-Last update: December 2001 / Text revised; profile added.

[ 1] Toh-E A., Yasunaga S., Nisogi H., Tanaka K., Oguchi T., Matsui Y.
     Yeast 9:481-494(1993).
[ 2] Bairoch A.
     Unpublished observations (1994).
[ 3] Mrsa V., Seidl T., Gentzsch M., Tanner W.
     "Specific labelling of cell wall proteins by biotinylation.
     Identification of four covalently linked O-mannosylated proteins of
     Saccharomyces cerevisiae."
     Yeast 13:1145-1154(1997).
     PubMed=9301021; DOI=10.1002/(SICI)1097-0061(19970930)13:12<1145::AID-YEA163>3.0.CO;2-Y

--------------------------------------------------------------------------------
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and
distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives
(CC BY-NC-ND 4.0) License, see https://prosite.expasy.org/prosite_license.html
--------------------------------------------------------------------------------

{END}