{PDOC00801}
{PS01043; TRANSPOSASE_IS30}
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* Transposases, IS30 family, signature *
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Autonomous mobile genetic elements  such as  transposon or insertion sequences
(IS) encode an enzyme, called transposase, required for excising and inserting
the mobile element. On the basis of sequence similarities, transposases can be
grouped into various families.   One of these families has been shown [1,2] to
consist of transposases from the following elements:

 - Is30 from Escherichia coli.
 - Is1086 from Alcaligenes eutrophus.
 - Is1161 from Streptococcus salivarius.
 - Is4351 (Tn4551) from Bacteroides fragilis.

These transposases  are proteins of 340 to 380 amino acids. The best conserved
region is  located  in  their  C-terminal  section  and is used as a signature
pattern.

-Consensus pattern: R-G-x(2)-E-N-x-N-G-[LIVM](2)-R-[QE]-[LIVMFY](2)-P-K
-Sequences known to belong to this class detected by the pattern: ALL.
-Other sequence(s) detected in Swiss-Prot: NONE.
-Last update: November 1995 / First entry.

[ 1] Dong Q., Sadouk A., van der Lelie D., Taghavi S., Ferhat A.,
     Nuyten J.M., Borremans B., Mergeay M., Toussaint A.
     "Cloning and sequencing of IS1086, an Alcaligenes eutrophus insertion
     element related to IS30 and IS4351."
     J. Bacteriol. 174:8133-8138(1992).
     PubMed=1334071;
[ 2] Giffard P.M., Rathsam C., Kwan E., Kwan D.W.L., Bunny K.L., Koo S.-P.,
     Jacques N.A.
     "The ftf gene encoding the cell-bound fructosyltransferase of
     Streptococcus salivarius ATCC 25975 is preceded by an insertion
     sequence and followed by FUR1 and clpP homologues."
     J. Gen. Microbiol. 139:913-920(1993).
     PubMed=8393068;

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