PROSITE documentation PDOC00827

Ribosomal protein L37e signature

Description:

A number of eukaryotic and archaebacterial ribosomal proteins can be grouped on the basis of sequence similarities. One of these families consists of:

  • Mammalian L37 [1].
  • Leishmania infantum L37 [2].
  • Fission yeast YL35 [3].
  • Archaeal L37e (L35e) [4].

These proteins have 56 to 96 amino-acid residues. As a signature pattern, we selected a highly conserved region located in the N-terminal part of these proteins.

Last update:

April 2006 / Pattern revised.

Technical section:

PROSITE method (with tools and information) covered by this documentation:

RIBOSOMAL_L37E, PS01077Ribosomal protein L37e signature  (PATTERN)
Consensus pattern: G-T-x-[SAVTP]-x-G-x-[KRHIM]-x(4,5)-H-x(2)-C-x-R-C-G
Sequences known to belong to this class detected by the pattern: ALL
Other sequence(s) detected in Swiss-Prot: NONE
• Retrieve an alignment of Swiss-Prot true positive hits:
  Clustal format, color, condensed view  / Clustal format, color  / Clustal format, plain text  / Fasta format
Retrieve the sequence logo from the alignment
Taxonomic tree view of all Swiss-Prot/TrEMBL entries matching PS01077
Retrieve a list of all Swiss-Prot/TrEMBL entries matching PS01077
Scan Swiss-Prot/TrEMBL entries against PS01077
view ligand binding statistics
Matching PDB structures: 1FFK 1JJ2 1K5Y 1K73 ... [ALL]

References:

1 AuthorsChan Y.-L., Paz V., Olvera J., Wool I.G.
TitleThe primary structure of L37--a rat ribosomal protein with a zinc finger-like motif.
SourceBiochem. Biophys. Res. Commun. 192:590-596(1993).
PubMed ID8484768
2 AuthorsMartinez-Calvillo S., Sunkin S.M., Yan S., Fox M., Stuart K., Myler P.J.
TitleGenomic organization and functional characterization of the Leishmania major Friedlin ribosomal RNA gene locus.
SourceMol. Biochem. Parasitol. 116:147-157(2001).
PubMed ID11522348
3 AuthorsOtaka E., Higo K.-I., Itoh T.
TitleYeast ribosomal proteins: VII. Cytoplasmic ribosomal proteins from Schizosaccharomyces pombe.
SourceMol. Gen. Genet. 191:519-524(1983).
PubMed ID6355773
4 AuthorsBergmann U., Wittmann-Liebold B.
TitleHL35e and HLA: primary structure of two very basic and cysteine-rich ribosomal proteins from Haloarcula marismortui.
SourceBiochim. Biophys. Acta 1173:195-200(1993).
PubMed ID8504167

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