{PDOC00827} {PS01077; RIBOSOMAL_L37E} {BEGIN} ************************************ * Ribosomal protein L37e signature * ************************************ A number of eukaryotic and archaebacterial ribosomal proteins can be grouped on the basis of sequence similarities. One of these families consists of: - Mammalian L37 [1]. - Leishmania infantum L37 [2]. - Fission yeast YL35 [3]. - Archaeal L37e (L35e) [4]. These proteins have 56 to 96 amino-acid residues. As a signature pattern, we selected a highly conserved region located in the N-terminal part of these proteins. -Consensus pattern: G-T-x-[SAVTP]-x-G-x-[KRHIM]-x(4,5)-H-x(2)-C-x-R-C-G -Sequences known to belong to this class detected by the pattern: ALL. -Other sequence(s) detected in Swiss-Prot: NONE. -Last update: April 2006 / Pattern revised. [ 1] Chan Y.-L., Paz V., Olvera J., Wool I.G. "The primary structure of L37--a rat ribosomal protein with a zinc finger-like motif." Biochem. Biophys. Res. Commun. 192:590-596(1993). PubMed=8484768 [ 2] Martinez-Calvillo S., Sunkin S.M., Yan S., Fox M., Stuart K., Myler P.J. "Genomic organization and functional characterization of the Leishmania major Friedlin ribosomal RNA gene locus." Mol. Biochem. Parasitol. 116:147-157(2001). PubMed=11522348 [ 3] Otaka E., Higo K.-I., Itoh T. "Yeast ribosomal proteins: VII. Cytoplasmic ribosomal proteins from Schizosaccharomyces pombe." Mol. Gen. Genet. 191:519-524(1983). PubMed=6355773 [ 4] Bergmann U., Wittmann-Liebold B. "HL35e and HLA: primary structure of two very basic and cysteine-rich ribosomal proteins from Haloarcula marismortui." Biochim. Biophys. Acta 1173:195-200(1993). PubMed=8504167 -------------------------------------------------------------------------------- PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see https://prosite.expasy.org/prosite_license.html -------------------------------------------------------------------------------- {END}