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PROSITE documentation PDOC00831

Ribosomal protein L7Ae signature

Description:

A number of eukaryotic and archaebacterial ribosomal proteins can be grouped on the basis of sequence similarities. One of these families consists of:

  • Vertebrate L7A (SURF3) [1].
  • Plant L7A.
  • Yeast L7A (YL5) (Rp6).
  • Yeast protein NHP2 [2].
  • Yeast hypothetical protein YEL026w.
  • Bacillus subtilis hypothetical protein ylxQ.
  • Halobacterium marismortui Hs6.
  • Methanococcus jannaschii MJ1203.

These proteins have 100 to 265 amino-acid residues. As a signature pattern, we selected a conserved region located in the central section.

Last update:

December 2004 / Pattern and text revised.

Technical section:

PROSITE method (with tools and information) covered by this documentation:

RIBOSOMAL_L7AE, PS01082; Ribosomal protein L7Ae signature  (PATTERN)
Consensus pattern: [CAS]-x(4)-[IVA]-P-[FY]-x(2)-[LIVM]-x-[GSQNK]-[KRQ]-x(2)-L-G
Sequences known to belong to this class detected by the pattern: ALL
Other sequence(s) detected in Swiss-Prot: NONE
• Retrieve an alignment of Swiss-Prot true positive hits:
  Clustal format, color, condensed view  / Clustal format, color  / Clustal format, plain text  / Fasta format
• Retrieve the sequence logo from the alignment
• Taxonomic tree view of all Swiss-Prot/TrEMBL entries matching PS01082
• Retrieve a list of all Swiss-Prot/TrEMBL entries matching PS01082
• Scan Swiss-Prot/TrEMBL entries against PS01082
• view ligand binding statistics
Matching PDB structures: 1E7K 1FFK 1JJ2 1K5Y ... [ALL]

References:

1 AuthorsColombo P., Yon J., Garson K., Fried M.
TitleConservation of the organization of five tightly clustered genes over 600 million years of divergent evolution.
SourceProc. Natl. Acad. Sci. U.S.A. 89:6358-6362(1992).
PubMed ID1631131
2 AuthorsKolodrubetz D., Burgum A.
TitleSequence and genetic analysis of NHP2: a moderately abundant high mobility group-like nuclear protein with an essential function in Saccharomyces cerevisiae.
SourceYeast 7:79-90(1991).
PubMed ID2063628

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