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PROSITE documentation PDOC00891

Class A bacterial acid phosphatases signature

Description:

Class A bacterial acid phosphatases [1] (EC 3.1.3.2) are a family of related periplasmic enzymes. This family currently consist of:

  • Morganela morganii major phosphate-irrepressible acid phosphatase (HPAP) (gene phoC).
  • Providencia stuartii and Salmonella typhimurium nonspecific acid phosphatase (NSAP) (gene phoN).
  • Zymomonas mobilis acid phosphatase (gene phoC).

As a signature pattern, we selected the most conserved region, a perfectly conserved octapeptide located in the central region of these enzymes.

Last update:

November 1995 / First entry.

Technical section:

PROSITE method (with tools and information) covered by this documentation:

ACID_PHOSPH_CL_A, PS01157; Class A bacterial acid phosphatases signature  (PATTERN)
Consensus pattern: G-S-Y-P-S-G-H-T
Sequences known to belong to this class detected by the pattern: ALL
Other sequence(s) detected in Swiss-Prot: NONE
• Retrieve an alignment of Swiss-Prot true positive hits:
  Clustal format, color, condensed view  / Clustal format, color  / Clustal format, plain text  / Fasta format
• Retrieve the sequence logo from the alignment
• Taxonomic tree view of all Swiss-Prot/TrEMBL entries matching PS01157
• Retrieve a list of all Swiss-Prot/TrEMBL entries matching PS01157
• Scan Swiss-Prot/TrEMBL entries against PS01157
• view ligand binding statistics

Reference:

1 AuthorsThaller M.C., Berlutti F., Schippa S., Lombardi G., Rossolini G.M.
TitleCharacterization and sequence of PhoC, the principal phosphate-irrepressible acid phosphatase of Morganella morganii.
SourceMicrobiology 140:1341-1350(1994).
PubMed ID8081499

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