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PROSITE documentation PDOC00901

Ribosomal protein L21e signature

Description:

A number of eukaryotic and archaebacterial ribosomal proteins can be grouped on the basis of sequence similarities. One of these families consists of:

  • Mammalian L21 [1].
  • Entamoeba histolytica L21 [2].
  • Caenorhabditis elegans L21 (C14B9.7).
  • Yeast L21E (URP1) [3].
  • Halobacterium marismortui HL31 [4].

These proteins have 160 (eukaryotes) or 95 (archebacteria) amino-acid residues. As a signature pattern, we selected a conserved region in the central part of these proteins.

Last update:

April 2006 / Pattern revised.

Technical section:

PROSITE method (with tools and information) covered by this documentation:

RIBOSOMAL_L21E, PS01171; Ribosomal protein L21e signature  (PATTERN)
Consensus pattern: [GN]-[DEQ]-x-V-x(10,11)-[GVT]-x(2)-[FYHDN]-x(2)-[FY]-x-G-x-[TV]-G
Sequences known to belong to this class detected by the pattern: ALL
Other sequence(s) detected in Swiss-Prot: NONE
• Retrieve an alignment of Swiss-Prot true positive hits:
  Clustal format, color, condensed view  / Clustal format, color  / Clustal format, plain text  / Fasta format
• Retrieve the sequence logo from the alignment
• Taxonomic tree view of all Swiss-Prot/TrEMBL entries matching PS01171
• Retrieve a list of all Swiss-Prot/TrEMBL entries matching PS01171
• Scan Swiss-Prot/TrEMBL entries against PS01171
• view ligand binding statistics
Matching PDB structures: 1FFK 1JJ2 1K5Y 1K73 ... [ALL]

References:

1 AuthorsDevi K.R.G., Chan Y.-L., Wool I.G.
TitleThe primary structure of rat ribosomal protein L21.
SourceBiochem. Biophys. Res. Commun. 162:364-370(1989).
PubMed ID2751657
2 AuthorsPetter R., Rozenblatt S., Nuchamowitz Y., Mirelman D.
TitleLinkage between actin and ribosomal protein L21 genes in Entamoeba histolytica.
SourceMol. Biochem. Parasitol. 56:329-333(1992).
PubMed ID1484554
3 AuthorsJank B., Waldherr M., Schweyen R.J.
TitleYeast single copy gene URP1 is a homolog of rat ribosomal protein gene L21.
SourceCurr. Genet. 23:15-18(1993).
PubMed ID8428379
4 AuthorsHatakeyama T., Kimura M.
TitleComplete amino acid sequences of the ribosomal proteins L25, L29 and L31 from the archaebacterium Halobacterium marismortui.
SourceEur. J. Biochem. 172:703-711(1988).
PubMed ID3350019

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