{PDOC01008} {PS01304; UBIH} {BEGIN} ******************************************** * ubiH/COQ6 monooxygenase family signature * ******************************************** The following proteins are evolutionary related: - Escherichia coli ubiH, which is involved in ubiquinone biosynthesis and which catalyzes the convertion of 2-octaprenyl-6-methoxyphenol to 2- octaprenyl-6-methoxy-1,4-benzoquinone. - Yeast COQ6, a ubiquinone biosynthesis monooxygenase. - Caenorhabditis elegans hypothetical protein K07B1.2. - Escherichia coli protein visC. - Escherichia coli hypothetical protein yleB. - Synechocystis strain PCC 6803 hypothetical protein slr1300. UbiH and COQ6 are monooxygenases that requires FAD as a cofactor. These are proteins of 42 to 54 Kd that can be picked up by the following pattern. -Consensus pattern: H-P-[LIV]-[AG]-G-Q-G-x-N-x-G-x(2)-D -Sequences known to belong to this class detected by the pattern: ALL. -Other sequence(s) detected in Swiss-Prot: NONE. -Last update: July 1998 / First entry. -------------------------------------------------------------------------------- PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see https://prosite.expasy.org/prosite_license.html -------------------------------------------------------------------------------- {END}