Phosphatidate cytidylyltransferase (EC 188.8.131.52) [1,2,3] (also known as CDP-diacylglycerol synthase) (CDS) is the enzyme that catalyzes the synthesis of
CDP-diacylglycerol from CTP and phosphatidate (PA). CDP-diacylglycerol is an
important branch point intermediate in both prokaryotic and eukaryotic
organisms. CDS is a membrane-bound enzyme. As a signature pattern we selected
a conserved region located in the C-terminal part.
December 2004 / Pattern and text revised.
PROSITE method (with tools and information) covered by this documentation:
Sparrow C.P., Raetz C.R.H.
Purification and properties of the membrane-bound CDP-diglyceride synthetase from Escherichia coli.
PROSITE is copyright. It is produced by the SIB Swiss Institute
Bioinformatics. There are no restrictions on its use by non-profit
institutions as long as its content is in no way modified. Usage by and
for commercial entities requires a license agreement. For information
about the licensing scheme send an email to
or see: prosite_license.html.