PROSITE documentation PDOC01023

Ribosome-binding factor A signature

Description

Ribosome-binding factor A [1] (gene rbfA) is a bacterial protein that associates with free 30S ribosomal subunits. It does not associates with 30S subunits that are part of 70S ribosomes or polysomes. It is essential for efficient processing of 16S rRNA.

Ribosome-binding factor A is a protein of from 13 to 15 Kd which is found in most prokaryotic organisms. A putative chloroplastic form seems to exist in plants [2].

As a signature pattern, we selected the best conserved region which is located in the second half of the protein.

Last update:

December 2004 / Pattern and text revised.

Technical section

PROSITE method (with tools and information) covered by this documentation:

RBFA, PS01319; Ribosome-binding factor A signature  (PATTERN)
Consensus pattern: [LIVMF]-[QKRHSA]-{E}-x-[LIVMAC]-x(5,6)-[LIVMW]-[RKAYF]-x-[STACIVMF]-[PV]-{LG}-[LIVMF]-x-[FYI]-x(2)-D
Sequences known to belong to this class detected by the pattern: ALL
Other sequence(s) detected in Swiss-Prot: NONE
• Retrieve an alignment of Swiss-Prot true positive hits:
  Clustal format, color, condensed view  / Clustal format, color  / Clustal format, plain text  / Fasta format
• Retrieve the sequence logo from the alignment
• Taxonomic tree view of all Swiss-Prot/TrEMBL entries matching PS01319
• Retrieve a list of all Swiss-Prot/TrEMBL entries matching PS01319
• Scan Swiss-Prot/TrEMBL entries against PS01319
• view ligand binding statistics
Matching PDB structures: 1JOS 1KKG 1PA4 2E7G ... [ALL]

References

1 Authors Bylund G.O., Wipemo L.C., Lundberg L.A., Wikstrom P.M.
Title RimM and RbfA are essential for efficient processing of 16S rRNA in Escherichia coli.
Source J. Bacteriol. 180:73-82(1998).
PubMed ID 9422595
2 Authors Bairoch A.
Source Unpublished observations (1998).

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