Entry: PS00021

General information about the entry
Entry name KRINGLE_1
Accession number PS00021
Entry type PATTERN
Date APR-1990 (CREATED); SEP-2002 (DATA UPDATE); MAR-2013 (INFO UPDATE).
PROSITE Documentation PDOC00020
Name and characterization of the entry
DescriptionKringle domain signature.
Pattern [FY]-C-[RH]-[NS]-x(7,8)-[WY]-C.
Numerical results
  • UniProtKB/Swiss-Prot release number: 2013_05, total number of sequence entries in that release: 540052.
  • Total number of hits in UniProtKB/Swiss-Prot: 216 hits in 95 different sequences
  • Number of hits on proteins that are known to belong to the set under consideration: 214 hits in 93 different sequences
  • Number of hits on proteins that could potentially belong to the set under consideration: 0 hits in 0 different sequences
  • Number of false hits (on unrelated proteins): 2 hits in 2 different sequences
  • Number of known missed hits: 1
  • Number of partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences: 1
  • Precision (true hits / (true hits + false positives)): 99.07 %
  • Recall (true hits / (true hits + false negatives)): 99.53 %
Comments
  • Taxonomic range: Eukaryotes
  • Maximum known number of repetitions of the pattern in a single protein: 38
  • `Interesting' site in the pattern: 2,disulfide
  • `Interesting' site in the pattern: 7,disulfide
  • VERSION: 1
Cross-references
UniProtKB/Swiss-Prot True positive hits:
APOA_HUMAN  (P08519), APOA_MACMU  (P14417), FA12_CAVPO  (Q04962), 
FA12_HUMAN  (P00748), FA12_MOUSE  (Q80YC5), FA12_PIG    (O97507), 
FA12_RAT    (D3ZTE0), HABP2_BOVIN (Q5E9Z2), HABP2_HUMAN (Q14520), 
HABP2_MOUSE (Q8K0D2), HABP2_RAT   (Q6L711), HGFA_CANFA  (Q6QNF4), 
HGFA_HUMAN  (Q04756), HGFA_MOUSE  (Q9R098), HGFL_BOVIN  (Q24K22), 
HGFL_HUMAN  (P26927), HGFL_MOUSE  (P26928), HGF_BOVIN   (Q76BS1), 
HGF_CANFA   (Q867B7), HGF_FELCA   (Q9BH09), HGF_HUMAN   (P14210), 
HGF_MOUSE   (Q08048), HGF_RAT     (P17945), KREM1_HUMAN (Q96MU8), 
KREM1_MOUSE (Q99N43), KREM1_RAT   (Q924S4), KREM1_XENLA (Q90Y90), 
KREM2_HUMAN (Q8NCW0), KREM2_MOUSE (Q8K1S7), LPAL2_HUMAN (Q16609), 
MST1L_HUMAN (Q2TV78), MUSK_CHICK  (Q8AXY6), NETR_GORGO  (Q5G270), 
NETR_HUMAN  (P56730), NETR_MACMU  (Q5G267), NETR_MOUSE  (O08762), 
NETR_NOMLE  (Q5G268), NETR_PANTR  (Q5G271), NETR_PONPY  (Q5G269), 
NETR_RAT    (G3V801), NETR_SAGLB  (Q5G265), NETR_TRAPH  (Q5G266), 
P3IP1_BOVIN (Q1RMT9), P3IP1_DANRE (Q7SXB3), P3IP1_HUMAN (Q96FE7), 
P3IP1_MOUSE (Q7TMJ8), P3IP1_PONAB (Q5RCS3), P3IP1_RAT   (Q56A20), 
PLMN_BOVIN  (P06868), PLMN_CANFA  (P80009), PLMN_CAPHI  (Q7M323), 
PLMN_ERIEU  (Q29485), PLMN_HORSE  (P80010), PLMN_HUMAN  (P00747), 
PLMN_MACEU  (O18783), PLMN_MACMU  (P12545), PLMN_MOUSE  (P20918), 
PLMN_PETMA  (P33574), PLMN_PIG    (P06867), PLMN_PONAB  (Q5R8X6), 
PLMN_RAT    (Q01177), PLMN_SHEEP  (P81286), ROR1_DROME  (Q24488), 
ROR1_HUMAN  (Q01973), ROR1_MOUSE  (Q9Z139), ROR2_DROME  (Q9V6K3), 
ROR2_HUMAN  (Q01974), ROR2_MOUSE  (Q9Z138), THRB_BOVIN  (P00735), 
THRB_HUMAN  (P00734), THRB_MOUSE  (P19221), THRB_PIG    (Q19AZ8), 
THRB_PONAB  (Q5R537), THRB_RAT    (P18292), TPA_BOVIN   (Q28198), 
TPA_HUMAN   (P00750), TPA_MOUSE   (P11214), TPA_PIG     (Q8SQ23), 
TPA_PONAB   (Q5R8J0), TPA_RAT     (P19637), UROK_BOVIN  (Q05589), 
UROK_CHICK  (P15120), UROK_HUMAN  (P00749), UROK_MOUSE  (P06869), 
UROK_PAPCY  (P16227), UROK_PIG    (P04185), UROK_PONAB  (Q5RF29), 
UROK_RABIT  (Q8MHY7), UROK_RAT    (P29598), URT1_DESRO  (P98119), 
URT2_DESRO  (P15638), URTB_DESRO  (P98121), URTG_DESRO  (P49150)
False negative hits (sequences which belong to the set under consideration, but which have not been picked up by the pattern or profile):
FA12_BOVIN  (P98140)
`Potential' hits (partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences):
THRB_SALSA  (P84122)
False positive hits (sequences which do not belong to the set under consideration):
CO141_CONMI (Q3YEG4), PWAP_HALLA  (P84811)
Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:

[Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format]

Retrieve the sequence logo from the alignment

PDB
[Detailed view]
1A0H; 1B2I; 1BHT; 1CEA; 1CEB; 1GMN; 1GMO; 1GP9; 1HPJ; 1HPK; 1I5K; 1I71; 1JFN; 1KDU; 1KI0; 1KIV; 1KRN; 1NK1; 1NL1; 1NL2; 1PK2; 1PK4; 1PKR; 1PMK; 1PML; 1TPK; 1URK; 2DOH; 2DOI; 2FD6; 2FEB; 2HPP; 2HPQ; 2I9A; 2I9B; 2K4R; 2K51; 2KNF; 2L0S; 2PF1; 2PF2; 2PK4; 2QJ2; 2QJ4; 2SPT; 3BT1; 3BT2; 3E6P; 3HN4; 3K65; 3KIV; 3LAQ; 3MKP; 3NXP; 3SP8; 3U73; 4A5T; 4DUR; 4DUU; 4IUA; 4KIV; 5HPG;

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