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Entry: PS00024

General information about the entry

Entry name [info] HEMOPEXIN
Accession [info] PS00024
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED; 01-APR-2006 DATA UPDATE; 27-SEP-2017 INFO UPDATE.
PROSITE Doc. [info] PDOC00023

Name and characterization of the entry

Description [info] Hemopexin domain signature.
Pattern [info]
[LIFAT]-{IL}-x(2)-W-x(2,3)-[PE]-x-{VF}-[LIVMFY]-[DENQS]-[STA]-[AV]-
[LIVMFY].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2017_09 which contains 555'594 sequence entries.


Total number of hits 132 in 125 different sequences
Number of true positive hits 82 in 75 different sequences
Number of 'unknown' hits 0
Number of false positive hits 50 in 50 different sequences
Number of false negative sequences 23
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 62.12 %
Recall (true positives / (true positives + false negatives)) 78.10 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 2
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
75 sequences

HEMO_BOVIN  (Q3SZV7    ), HEMO_HUMAN  (P02790    ), HEMO_MOUSE  (Q91X72    ), 
HEMO_PIG    (P50828    ), HEMO_PONAB  (Q5R543    ), HEMO_RABIT  (P20058    ), 
HEMO_RAT    (P20059    ), HE_HEMPU    (P91953    ), MMP10_HUMAN (P09238    ), 
MMP10_MOUSE (O55123    ), MMP10_RAT   (P07152    ), MMP11_HUMAN (P24347    ), 
MMP11_MOUSE (Q02853    ), MMP11_RAT   (Q499S5    ), MMP11_XENLA (Q11005    ), 
MMP12_HUMAN (P39900    ), MMP12_MOUSE (P34960    ), MMP12_RABIT (P79227    ), 
MMP12_RAT   (Q63341    ), MMP13_HORSE (O18927    ), MMP13_HUMAN (P45452    ), 
MMP13_MOUSE (P33435    ), MMP13_RABIT (O62806    ), MMP13_RAT   (P23097    ), 
MMP13_XENLA (Q10835    ), MMP14_BOVIN (Q9GLE4    ), MMP14_HUMAN (P50281    ), 
MMP14_MOUSE (P53690    ), MMP14_PIG   (Q9XT90    ), MMP14_PONAB (Q5RES1    ), 
MMP14_RABIT (Q95220    ), MMP14_RAT   (Q10739    ), MMP15_HUMAN (P51511    ), 
MMP15_MOUSE (O54732    ), MMP16_HUMAN (P51512    ), MMP16_MOUSE (Q9WTR0    ), 
MMP16_RAT   (O35548    ), MMP19_MOUSE (Q9JHI0    ), MMP1A_MOUSE (Q9EPL5    ), 
MMP1B_MOUSE (Q9EPL6    ), MMP1_BOVIN  (P28053    ), MMP1_HORSE  (Q9XSZ5    ), 
MMP1_HUMAN  (P03956    ), MMP1_PIG    (P21692    ), MMP1_RABIT  (P13943    ), 
MMP24_HUMAN (Q9Y5R2    ), MMP24_MOUSE (Q9R0S2    ), MMP24_RAT   (Q99PW6    ), 
MMP27_HUMAN (Q9H306    ), MMP27_TUPBE (Q9GKE1    ), MMP2_BOVIN  (Q9GLE5    ), 
MMP2_CHICK  (Q90611    ), MMP2_HUMAN  (P08253    ), MMP2_MOUSE  (P33434    ), 
MMP2_RABIT  (P50757    ), MMP2_RAT    (P33436    ), MMP3_CANLF  (Q6Y4Q5    ), 
MMP3_HORSE  (Q28397    ), MMP3_HUMAN  (P08254    ), MMP3_MOUSE  (P28862    ), 
MMP3_RABIT  (P28863    ), MMP3_RAT    (P03957    ), MMP8_HUMAN  (P22894    ), 
MMP8_MOUSE  (O70138    ), MMP8_RAT    (O88766    ), MMP9_HUMAN  (P14780    ), 
MMP9_MOUSE  (P41245    ), MMP9_RABIT  (P41246    ), MMP9_RAT    (P50282    ), 
PRG4_HUMAN  (Q92954    ), PRG4_MOUSE  (Q9JM99    ), VTNC_HUMAN  (P04004    ), 
VTNC_MOUSE  (P29788    ), VTNC_PIG    (P48819    ), VTNC_RABIT  (P22458    )
» more

UniProtKB/Swiss-Prot
False negative sequences
23 sequences

D2MP_DROME  (Q8MPP3    ), HE_PARLI    (P22757    ), MMP13_BOVIN (O77656    ), 
MMP17_HUMAN (Q9ULZ9    ), MMP17_MOUSE (Q9R0S3    ), MMP18_XENLA (O13065    ), 
MMP19_HUMAN (Q99542    ), MMP1_LITCT  (Q11133    ), MMP20_BOVIN (O18767    ), 
MMP20_HUMAN (O60882    ), MMP20_MOUSE (P57748    ), MMP20_PIG   (P79287    ), 
MMP21_CYNPY (Q90YC2    ), MMP21_HUMAN (Q8N119    ), MMP21_MOUSE (Q8K3F2    ), 
MMP21_XENLA (O93470    ), MMP25_HUMAN (Q9NPA2    ), MMP25_MOUSE (Q3U435    ), 
MMP28_HUMAN (Q9H239    ), MMP9_BOVIN  (P52176    ), MMP9_CANLF  (O18733    ), 
MMPA_CAEEL  (G5EGM1    ), MMPC_CAEEL  (G5EBU3    )
» more

UniProtKB/Swiss-Prot
'Partial' sequences
1 sequence

HEMO_CHICK  (P20057    )

		
UniProtKB/Swiss-Prot
False positive sequences
50 sequences

ASTE_PARXL  (Q141D1    ), BPHA4_RHOJR (Q0S032    ), CE042_MOUSE (Q8CE72    ), 
DPP6_PANTR  (Q5IS50    ), GC_PSHV1    (Q6UDI7    ), HISX_PROMM  (Q7V5N9    ), 
KATG_MYCGI  (A4TA35    ), LGRC_BREPA  (Q70LM5    ), LTD_ORYSI   (A2YLX7    ), 
LTD_ORYSJ   (A3BKF2    ), MPPE1_AILME (D2I2M6    ), MPPE1_CHICK (Q5ZK82    ), 
MPPE1_CRIGR (C7G3A0    ), MPPE1_HUMAN (Q53F39    ), MPPE1_MACFA (Q9GMS6    ), 
MPPE1_MOUSE (Q80XL7    ), MPPE1_PONAB (Q5RET5    ), MPPE1_RAT   (B1WC86    ), 
MPPE1_XENLA (Q0IHA5    ), MSLN_HUMAN  (Q13421    ), NIFJ_ECOLI  (P52647    ), 
OPGG2_SHEON (Q8EDL2    ), PMA6E_HUMAN (A0A0J9YXQ4), PORCN_CAEBR (A8WZ09    ), 
STEA4_HUMAN (Q687X5    ), STEA4_MOUSE (Q923B6    ), SYE1_SPHWW  (A5V932    ), 
SYT_HAEDU   (Q7VKR9    ), TFE_METTP   (A0B9P3    ), TMCA_CITK8  (A8ADB3    ), 
TRAK1_HUMAN (Q9UPV9    ), TRAK1_MOUSE (Q6PD31    ), TYSY_HALVO  (Q9UWQ5    ), 
UBID_BURCA  (Q1BYC0    ), UBID_BURL3  (Q39IR6    ), UBID_BURMA  (Q62HU9    ), 
UBID_BURP1  (Q3JPM4    ), UBID_BURPS  (Q63RP1    ), UBID_BURTA  (Q2SYC8    ), 
UBID_METCA  (Q602K0    ), UBID_NITEU  (Q82TP1    ), UBID_THIDA  (Q3SMI8    ), 
URE1_ACIAD  (Q6FD83    ), URE1_CORGL  (Q79VJ3    ), UTP20_SCHPO (O60055    ), 
Y022_ALKMQ  (A6TJ97    ), Y1488_MYCTO (P9WPR8    ), Y1488_MYCTU (P9WPR9    ), 
Y1524_MYCBO (P63694    ), Y3298_MAGMM (A0LCU4    )
» more

PDB
[Detailed view]
20 PDB

1CK7; 1FBL; 1GEN; 1GXD; 1HXN; 1ITV; 1PEX; 1QHU; 1QJS; 1RTG; 1SU3; 2CLT; 2JXY; 2MQS; 3BA0; 3C7X; 4AUO; 4FU4; 4FVL; 4G0D
» more

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