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Entry: PS00031

General information about the entry

Entry name [info] NUCLEAR_REC_DBD_1
Accession [info] PS00031
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED; 01-APR-2006 DATA UPDATE; 22-NOV-2017 INFO UPDATE.
PROSITE Doc. [info] PDOC00031

Name and characterization of the entry

Description [info] Nuclear hormones receptors DNA-binding region signature.
Pattern [info]
C-x(2)-C-x(1,2)-[DENAVSPHKQT]-x(5,6)-[HNY]-[FY]-x(4)-C-x(2)-C-x(2)-F(2)-
x-R.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2017_11 which contains 556'196 sequence entries.


Total number of hits 451 in 451 different sequences
Number of true positive hits 451 in 451 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 8
Number of 'partial' sequences 9
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 98.26 %

Comments [info]

Taxonomic range [info] Eukaryotes, Eukaryotic viruses
Maximum number of repetitions [info] 1
Site [info] zinc at position 1
Site [info] zinc at position 3
Site [info] zinc at position 10
Site [info] zinc at position 12
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
451 sequences

7UP1_DROME  (P16375    ), 7UP2_DROME  (P16376    ), ANDR_CANLF  (Q9TT90    ), 
ANDR_CROCR  (Q8MIK0    ), ANDR_EULFC  (O97776    ), ANDR_HUMAN  (P10275    ), 
ANDR_LITCT  (Q7T1K4    ), ANDR_MACFA  (O97952    ), ANDR_MACMU  (Q6QT55    ), 
ANDR_MOUSE  (P19091    ), ANDR_PANTR  (O97775    ), ANDR_PAPHA  (O97960    ), 
ANDR_PIG    (Q9GKL7    ), ANDR_RABIT  (P49699    ), ANDR_RAT    (P15207    ), 
CNR14_CAEEL (P41830    ), COT1_BOVIN  (Q9TTR8    ), COT1_HUMAN  (P10589    ), 
COT1_MOUSE  (Q60632    ), COT2_BOVIN  (Q9TTR7    ), COT2_CHICK  (Q90733    ), 
COT2_HUMAN  (P24468    ), COT2_MOUSE  (P43135    ), COT2_RAT    (O09018    ), 
DAF12_CAEEL (G5EFF5    ), E75BB_DROME (P13055    ), E75BC_DROME (P17671    ), 
E75_CHOFU   (O01639    ), E75_GALME   (P50239    ), E75_MANSE   (Q08893    ), 
E75_METEN   (O77245    ), E78C_DROME  (P45447    ), ECR_AEDAE   (P49880    ), 
ECR_BOMMO   (P49881    ), ECR_CHITE   (P49882    ), ECR_DROME   (P34021    ), 
ECR_HELVI   (O18473    ), ECR_LUCCU   (O18531    ), ECR_MANSE   (P49883    ), 
EGON_DROME  (P15370    ), ERR1_CANLF  (Q6QMY5    ), ERR1_HUMAN  (P11474    ), 
ERR1_MOUSE  (O08580    ), ERR1_RAT    (Q5QJV7    ), ERR2_HUMAN  (O95718    ), 
ERR2_MOUSE  (Q61539    ), ERR2_RAT    (P11475    ), ERR3_HUMAN  (P62508    ), 
ERR3_MOUSE  (P62509    ), ERR3_PONAB  (Q5RAM2    ), ERR3_RAT    (P62510    ), 
ESR1_BOVIN  (P49884    ), ESR1_CHICK  (P06212    ), ESR1_DANRE  (P57717    ), 
ESR1_FELCA  (Q53AD2    ), ESR1_HORSE  (Q9TV98    ), ESR1_HUMAN  (P03372    ), 
ESR1_ICTPU  (Q9YHZ7    ), ESR1_MESAU  (Q9QZJ5    ), ESR1_MOUSE  (P19785    ), 
ESR1_ONCMY  (P16058    ), ESR1_OREAU  (P50240    ), ESR1_ORENI  (Q9YH33    ), 
ESR1_ORYLA  (P50241    ), ESR1_PAGMA  (O42132    ), ESR1_PIG    (Q29040    ), 
ESR1_RAT    (P06211    ), ESR1_SALSA  (P50242    ), ESR1_SHEEP  (P49885    ), 
ESR1_SPAAU  (Q9PVZ9    ), ESR1_TAEGU  (Q91250    ), ESR1_XENLA  (P81559    ), 
ESR21_CARAU (Q9W669    ), ESR22_CARAU (Q9IAL9    ), ESR2_ANGJA  (O13012    ), 
ESR2_BOVIN  (Q9XSB5    ), ESR2_CALJA  (Q95171    ), ESR2_CHICK  (Q9PTU5    ), 
ESR2_COTJA  (O93511    ), ESR2_HUMAN  (Q92731    ), ESR2_ICTPU  (Q9IAK1    ), 
ESR2_MICUN  (P57781    ), ESR2_MOUSE  (O08537    ), ESR2_ONCMY  (P57782    ), 
ESR2_ORENI  (Q9YH32    ), ESR2_PIG    (Q9XSW2    ), ESR2_RAT    (Q62986    ), 
ESR2_SHEEP  (Q9TU15    ), ESR2_SPAAU  (Q9W6M2    ), ESR2_STUVU  (Q9PVE2    ), 
ESR3_MICUN  (P57783    ), FTF1B_DROME (Q05192    ), FTZF1_BOMMO (P49867    ), 
FTZF1_DROME (P33244    ), GAG_AVIER   (P03373    ), GCNFA_DANRE (Q9PU65    ), 
GCNFB_DANRE (Q4V8R7    ), GCR_AOTNA   (P79686    ), GCR_CALJA   (Q6XLJ0    ), 
GCR_CAVPO   (P49115    ), GCR_HUMAN   (P04150    ), GCR_MOUSE   (P06537    ), 
GCR_ONCMY   (P49843    ), GCR_PAROL   (O73673    ), GCR_PIG     (Q9N1U3    ), 
GCR_PONAB   (Q5R9P5    ), GCR_RABIT   (P59667    ), GCR_RAT     (P06536    ), 
GCR_SAGOE   (P79269    ), GCR_SAIBB   (O13186    ), GCR_SAISC   (O46567    ), 
GCR_SHEEP   (P35547    ), GCR_TUPBE   (Q95267    ), GCR_XENLA   (P49844    ), 
HIZR1_CAEEL (G5ED47    ), HNF4A_HUMAN (P41235    ), HNF4A_MOUSE (P49698    ), 
HNF4A_RAT   (P22449    ), HNF4A_XENLA (Q91766    ), HNF4B_XENLA (P79926    ), 
HNF4G_HUMAN (Q14541    ), HNF4G_MOUSE (Q9WUU6    ), HNF4_DROME  (P49866    ), 
HR38_BOMMO  (P49870    ), HR38_DROME  (P49869    ), HR3_DROME   (P31396    ), 
HR3_GALME   (P49868    ), HR3_MANSE   (Q08882    ), HR4_DROME   (Q9W539    ), 
HR78_DROME  (Q24142    ), HR96_DROME  (Q24143    ), KNIR_DROME  (P10734    ), 
KNIR_DROVI  (Q24753    ), KNRL_DROME  (P13054    ), MCR_AOTNA   (Q3YC04    ), 
MCR_HUMAN   (P08235    ), MCR_MOUSE   (Q8VII8    ), MCR_RAT     (P22199    ), 
MCR_SAIBB   (Q4JM28    ), MCR_SAISC   (Q9N0W8    ), MCR_TUPBE   (Q29131    ), 
MCR_XENLA   (Q91573    ), N2C1A_XENLA (Q6GN21    ), N2C1B_XENLA (Q66J63    ), 
N2F1A_DANRE (Q06725    ), N2F1B_DANRE (Q6PH18    ), NH100_CAEEL (O17611    ), 
NH103_CAEEL (O16359    ), NH106_CAEEL (O16966    ), NH111_CAEEL (O45521    ), 
NH115_CAEEL (O16662    ), NH121_CAEEL (Q9TZ99    ), NH124_CAEEL (O16391    ), 
NH125_CAEEL (O17082    ), NH127_CAEEL (O18087    ), NH133_CAEEL (O16354    ), 
NH134_CAEEL (O16361    ), NH136_CAEEL (O01930    ), NH150_CAEEL (O17573    ), 
NH153_CAEEL (O01929    ), NH154_CAEEL (O01931    ), NH164_CAEEL (O17657    ), 
NH169_CAEEL (O17706    ), NH174_CAEEL (O17748    ), NH217_CAEEL (O02305    ), 
NH268_CAEEL (O17930    ), NHR10_CAEEL (P41999    ), NHR11_CAEEL (Q23294    ), 
NHR12_CAEEL (Q21701    ), NHR13_CAEEL (Q9N4Q7    ), NHR14_CAEEL (O02151    ), 
NHR16_CAEEL (Q27521    ), NHR18_CAEEL (O16360    ), NHR19_CAEEL (Q09528    ), 
NHR1_CAEEL  (Q21878    ), NHR1_ONCVO  (Q25604    ), NHR20_CAEEL (Q09565    ), 
NHR22_CAEEL (Q09587    ), NHR23_CAEEL (P41828    ), NHR25_CAEEL (Q19345    ), 
NHR28_CAEBR (A8XNK6    ), NHR28_CAEEL (Q17905    ), NHR2_CAEEL  (Q10902    ), 
NHR31_CAEEL (Q18192    ), NHR34_CAEEL (Q21006    ), NHR35_CAEEL (Q17771    ), 
NHR3_CAEEL  (Q9XTJ4    ), NHR40_CAEEL (Q22127    ), NHR41_CAEEL (Q9N4B8    ), 
NHR42_CAEEL (O76828    ), NHR44_CAEEL (Q22555    ), NHR47_CAEEL (Q17370    ), 
NHR48_CAEEL (Q94407    ), NHR49_CAEEL (O45666    ), NHR4_CAEEL  (O45436    ), 
NHR52_CAEEL (O17928    ), NHR53_CAEEL (O17933    ), NHR54_CAEEL (O45460    ), 
NHR55_CAEEL (O16962    ), NHR57_CAEEL (O16425    ), NHR59_CAEEL (Q9TXJ1    ), 
NHR5_CAEEL  (Q9NA51    ), NHR60_CAEEL (O17898    ), NHR61_CAEEL (O62389    ), 
NHR62_CAEEL (O02279    ), NHR64_CAEEL (O44960    ), NHR65_CAEEL (O45907    ), 
NHR67_CAEEL (Q9XVV3    ), NHR69_CAEEL (P91829    ), NHR6_CAEEL  (P41829    ), 
NHR71_CAEEL (Q9GTD4    ), NHR75_CAEEL (O16604    ), NHR77_CAEEL (O02316    ), 
NHR79_CAEEL (O18141    ), NHR7_CAEEL  (Q20765    ), NHR85_CAEEL (Q9XUK7    ), 
NHR86_CAEEL (Q965W2    ), NHR89_CAEEL (O02235    ), NHR8_CAEEL  (Q9XYB7    ), 
NHR90_CAEEL (O17025    ), NHR91_CAEEL (Q9U2R6    ), NHR96_CAEEL (Q95X91    ), 
NHR97_CAEEL (Q9BJK5    ), NHR98_CAEEL (Q966I0    ), NHR9_CAEEL  (Q23489    ), 
NR1D1_BOVIN (Q08E02    ), NR1D1_HUMAN (P20393    ), NR1D1_MOUSE (Q3UV55    ), 
NR1D1_RAT   (Q63503    ), NR1D1_SHEEP (B3SV56    ), NR1D2_HUMAN (Q14995    ), 
NR1D2_MOUSE (Q60674    ), NR1D2_RAT   (Q63504    ), NR1H2_BOVIN (Q5BIS6    ), 
NR1H2_HUMAN (P55055    ), NR1H2_MOUSE (Q60644    ), NR1H2_RAT   (Q62755    ), 
NR1H3_BOVIN (Q5E9B6    ), NR1H3_HUMAN (Q13133    ), NR1H3_MOUSE (Q9Z0Y9    ), 
NR1H3_RAT   (Q62685    ), NR1H4_BOVIN (Q3SZL0    ), NR1H4_HUMAN (Q96RI1    ), 
NR1H4_MOUSE (Q60641    ), NR1H4_RAT   (Q62735    ), NR1I2_HUMAN (O75469    ), 
NR1I2_MACMU (Q8SQ01    ), NR1I2_MOUSE (O54915    ), NR1I2_RAT   (Q9R1A7    ), 
NR1I3_CALUR (P62044    ), NR1I3_HUMAN (Q14994    ), NR1I3_MACMU (Q8MIM3    ), 
NR1I3_MOUSE (O35627    ), NR1I3_PANTR (A2T7D9    ), NR1I3_PUSSI (P62045    ), 
NR1I3_RAT   (Q9QUS1    ), NR2C1_BOVIN (A0JNE3    ), NR2C1_HUMAN (P13056    ), 
NR2C1_MACFA (Q95K90    ), NR2C1_MOUSE (Q505F1    ), NR2C1_PONAB (Q5RCZ5    ), 
NR2C1_RAT   (Q8VIJ4    ), NR2C1_XENTR (Q28CK1    ), NR2C2_HUMAN (P49116    ), 
NR2C2_MOUSE (P49117    ), NR2C2_RAT   (P55094    ), NR2E1_CHICK (Q91379    ), 
NR2E1_HUMAN (Q9Y466    ), NR2E1_MOUSE (Q64104    ), NR2E1_ORYLA (Q9YGL3    ), 
NR2E1_XENLA (P70052    ), NR2E3_BOVIN (Q9TTF0    ), NR2E3_HUMAN (Q9Y5X4    ), 
NR2E3_MOUSE (Q9QXZ7    ), NR2F5_DANRE (Q06726    ), NR2F6_HUMAN (P10588    ), 
NR2F6_MOUSE (P43136    ), NR2F6_RAT   (O09017    ), NR4A1_BOVIN (Q0V8F0    ), 
NR4A1_CANLF (P51666    ), NR4A1_HUMAN (P22736    ), NR4A1_MOUSE (P12813    ), 
NR4A1_RAT   (P22829    ), NR4A1_XENLA (Q04913    ), NR4A2_BOVIN (Q08E53    ), 
NR4A2_HUMAN (P43354    ), NR4A2_MOUSE (Q06219    ), NR4A2_PONAB (Q5R5Y4    ), 
NR4A2_RAT   (Q07917    ), NR4A2_XENTR (A4IIG7    ), NR4A3_HUMAN (Q92570    ), 
NR4A3_MOUSE (Q9QZB6    ), NR4A3_RAT   (P51179    ), NR5A2_CHICK (O42101    ), 
NR5A2_HUMAN (O00482    ), NR5A2_MOUSE (P45448    ), NR5A2_RAT   (Q9QWM1    ), 
NR6A1_HUMAN (Q15406    ), NR6A1_MOUSE (Q64249    ), NR6A1_PIG   (A0P8Z4    ), 
NR6A1_XENLA (P70033    ), NR6A1_XENTR (Q66JK1    ), ODR7_CAEEL  (P41933    ), 
PPARA_CANLF (Q95N78    ), PPARA_CAVPO (O35507    ), PPARA_HUMAN (Q07869    ), 
PPARA_MOUSE (P23204    ), PPARA_PHACI (Q8HYL6    ), PPARA_RAT   (P37230    ), 
PPARA_XENLA (P37232    ), PPARD_CANLF (Q0ZAQ8    ), PPARD_HUMAN (Q03181    ), 
PPARD_MOUSE (P35396    ), PPARD_XENLA (P37233    ), PPARG_BOVIN (O18971    ), 
PPARG_CANLF (Q4U3Q4    ), PPARG_CRIGR (P57797    ), PPARG_HUMAN (P37231    ), 
PPARG_MACMU (O18924    ), PPARG_MOUSE (P37238    ), PPARG_PIG   (O62807    ), 
PPARG_RABIT (O19052    ), PPARG_RAT   (O88275    ), PPARG_XENLA (P37234    ), 
PRGR_ATEPA  (A7XW25    ), PRGR_CANLF  (Q9GLW0    ), PRGR_CHICK  (P07812    ), 
PRGR_CHLAE  (A7X8C9    ), PRGR_COLGU  (A7X8D2    ), PRGR_GORGO  (A7X8B7    ), 
PRGR_HUMAN  (P06401    ), PRGR_HYLLA  (A7X8C2    ), PRGR_MACSY  (A7X8C4    ), 
PRGR_MOUSE  (Q00175    ), PRGR_PANPA  (A7X8B5    ), PRGR_PANTR  (A7X8B3    ), 
PRGR_PAPAN  (A7X8C7    ), PRGR_PITIR  (A7XW20    ), PRGR_PONPY  (A7X8B9    ), 
PRGR_RABIT  (P06186    ), PRGR_RANDY  (Q8AYI2    ), PRGR_RAT    (Q63449    ), 
PRGR_SAPAP  (A7XW16    ), PRGR_SHEEP  (Q28590    ), PRGR_TRAOB  (A7X8D4    ), 
RARAA_DANRE (Q90271    ), RARAB_DANRE (Q7ZTI3    ), RARA_CANLF  (Q5FBR4    ), 
RARA_CHICK  (Q90966    ), RARA_HUMAN  (P10276    ), RARA_MOUSE  (P11416    ), 
RARA_NOTVI  (P18514    ), RARA_TAKRU  (Q9W5Z3    ), RARA_XENLA  (P51126    ), 
RARB_CHICK  (P22448    ), RARB_COTJA  (Q9W6B3    ), RARB_HUMAN  (P10826    ), 
RARB_MOUSE  (P22605    ), RARB_NOTVI  (P18515    ), RARGA_DANRE (Q91392    ), 
RARGB_DANRE (A2T928    ), RARG_HUMAN  (P13631    ), RARG_MOUSE  (P18911    ), 
RARG_NOTVI  (P18516    ), RARG_XENLA  (P28699    ), RORA_HUMAN  (P35398    ), 
RORA_MOUSE  (P51448    ), RORB_HUMAN  (Q92753    ), RORB_MOUSE  (Q8R1B8    ), 
RORB_RAT    (P45446    ), RORG_HUMAN  (P51449    ), RORG_MOUSE  (P51450    ), 
RORG_PONAB  (Q5RAP4    ), RXRAA_DANRE (A2T929    ), RXRAB_DANRE (Q90415    ), 
RXRA_HUMAN  (P19793    ), RXRA_MOUSE  (P28700    ), RXRA_RAT    (Q05343    ), 
RXRA_XENLA  (P51128    ), RXRBA_DANRE (Q7SYN5    ), RXRBB_DANRE (Q90417    ), 
RXRB_CANLF  (Q5TJF7    ), RXRB_HUMAN  (P28702    ), RXRB_MOUSE  (P28704    ), 
RXRB_RAT    (P49743    ), RXRGA_DANRE (Q90416    ), RXRGB_DANRE (Q6DHP9    ), 
RXRG_BOVIN  (Q0VC20    ), RXRG_CHICK  (P28701    ), RXRG_HUMAN  (P48443    ), 
RXRG_MOUSE  (P28705    ), RXRG_PIG    (Q0GFF6    ), RXRG_PONAB  (Q5REL6    ), 
RXRG_RAT    (Q5BJR8    ), RXRG_XENLA  (P51129    ), RXR_BIOGL   (Q8T5C6    ), 
RXR_LYMST   (Q5I7G2    ), SHR2_STRPU  (Q26622    ), STF1_BOVIN  (Q04752    ), 
STF1_HORSE  (Q9GKL2    ), STF1_HUMAN  (Q13285    ), STF1_MACEU  (Q95L87    ), 
STF1_MOUSE  (P33242    ), STF1_PIG    (P79387    ), STF1_RAT    (P50569    ), 
THAA_DANRE  (Q98867    ), THAA_PAROL  (Q91241    ), THAA_XENLA  (P15204    ), 
THAB_PAROL  (Q91242    ), THAB_XENLA  (P18115    ), THA_APTPA   (O42295    ), 
THA_CAIMO   (Q90382    ), THA_CHICK   (P04625    ), THA_HIPHI   (Q9W6N4    ), 
THA_HUMAN   (P10827    ), THA_LITCT   (Q02777    ), THA_MOUSE   (P63058    ), 
THA_NECMA   (O57606    ), THA_PIG     (O97716    ), THA_PYGAD   (O42450    ), 
THA_RAT     (P63059    ), THA_SALSA   (Q9W785    ), THA_SHEEP   (Q28570    ), 
THBA_XENLA  (P18117    ), THBB_XENLA  (P18119    ), THB_CAIMO   (P68305    ), 
THB_CHICK   (P68306    ), THB_DANRE   (Q9PVE4    ), THB_HUMAN   (P10828    ), 
THB_LITCT   (Q02965    ), THB_MOUSE   (P37242    ), THB_PAROL   (Q91279    ), 
THB_RAT     (P18113    ), THB_SHEEP   (Q28571    ), TLL_DROME   (P18102    ), 
TLL_DROVI   (O16845    ), USP_BOMMO   (P49700    ), USP_CHOFU   (O76202    ), 
USP_DROME   (P20153    ), USP_MANSE   (P54779    ), VDRA_DANRE  (Q9PTN2    ), 
VDRB_DANRE  (Q1L673    ), VDR_BOVIN   (Q28037    ), VDR_CHICK   (O42392    ), 
VDR_COTJA   (P49701    ), VDR_HUMAN   (P11473    ), VDR_MOUSE   (P48281    ), 
VDR_PIG     (A3RGC1    ), VDR_RAT     (P13053    ), VDR_SAGOE   (Q95MH5    ), 
VDR_XENLA   (O13124    )
» more

UniProtKB/Swiss-Prot
False negative sequences
8 sequences

NH108_CAEEL (O45449    ), NH130_CAEEL (O16963    ), NH167_CAEEL (O17683    ), 
NH197_CAEEL (O17931    ), NH199_CAEEL (O17934    ), NH213_CAEEL (O18048    ), 
NH218_CAEEL (O18086    ), NHR51_CAEEL (O17927    )
» more

UniProtKB/Swiss-Prot
'Partial' sequences
9 sequences

ESR1_ANOCA  (Q9YHT3    ), ESR1_ASPUN  (Q91424    ), ESR1_MACMU  (P49886    ), 
ESR1_MICUN  (P57753    ), ESR2_MACMU  (Q9TTE5    ), PRGR_MACEU  (P79373    ), 
THA_ELECQ   (Q9PUA8    ), THA_ONCMY   (Q9W6I9    ), THA_SPAAU   (O57568    )
» more

PDB
[Detailed view]
71 PDB

1A6Y; 1BY4; 1CIT; 1DSZ; 1GA5; 1GDC; 1GLU; 1HCP; 1HCQ; 1HLZ; 1HRA; 1KB2; 1KB4; 1KB6; 1LAT; 1LO1; 1R0N; 1R0O; 1R4I; 1R4O; 1R4R; 1RGD; 1RXR; 1YNW; 2A66; 2C7A; 2EBL; 2ENV; 2FF0; 2GDA; 2HAN; 2NLL; 3CBB; 3DZU; 3DZY; 3E00; 3FYL; 3G6P; 3G6Q; 3G6R; 3G6T; 3G6U; 3G8U; 3G8X; 3G97; 3G99; 3G9I; 3G9J; 3G9M; 3G9O; 3G9P; 3M9E; 4AA6; 4CN2; 4CN3; 4CN5; 4CN7; 4HN5; 4HN6; 4IQR; 4NQA; 4TNT; 4UMM; 5CBX; 5CBY; 5CBZ; 5CC0; 5CC1; 5EMC; 5EMP; 5EMQ
» more

View entry in original PROSITE format
View entry in raw text format (no links)
Direct ScanProsite submission