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| Entry: PS00031 |
| General information about the entry | |
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| Entry name | NUCLEAR_REC_DBD_1 |
| Accession number | PS00031 |
| Entry type | PATTERN |
| Date | APR-1990 (CREATED); APR-2006 (DATA UPDATE); MAR-2013 (INFO UPDATE). |
| PROSITE Documentation | PDOC00031 |
| Name and characterization of the entry | |
| Description | Nuclear hormones receptors DNA-binding region signature. |
| Pattern | C-x(2)-C-x(1,2)-[DENAVSPHKQT]-x(5,6)-[HNY]-[FY]-x(4)-C-x(2)-C-x(2)-F(2)- x-R. |
| Numerical results | |
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| Comments | |
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| Cross-references | |
| UniProtKB/Swiss-Prot | True positive hits:7UP1_DROME (P16375), 7UP2_DROME (P16376), ANDR_CANFA (Q9TT90), ANDR_CROCR (Q8MIK0), ANDR_EULFC (O97776), ANDR_HUMAN (P10275), ANDR_LITCT (Q7T1K4), ANDR_MACFA (O97952), ANDR_MACMU (Q6QT55), ANDR_MOUSE (P19091), ANDR_PANTR (O97775), ANDR_PAPHA (O97960), ANDR_PIG (Q9GKL7), ANDR_RABIT (P49699), ANDR_RAT (P15207), CNR14_CAEEL (P41830), COT1_BOVIN (Q9TTR8), COT1_HUMAN (P10589), COT1_MOUSE (Q60632), COT2_BOVIN (Q9TTR7), COT2_CHICK (Q90733), COT2_HUMAN (P24468), COT2_MOUSE (P43135), COT2_RAT (O09018), E75BB_DROME (P13055), E75BC_DROME (P17671), E75_CHOFU (O01639), E75_GALME (P50239), E75_MANSE (Q08893), E75_METEN (O77245), E78C_DROME (P45447), ECR_AEDAE (P49880), ECR_BOMMO (P49881), ECR_CHITE (P49882), ECR_DROME (P34021), ECR_HELVI (O18473), ECR_LUCCU (O18531), ECR_MANSE (P49883), EGON_DROME (P15370), ERR1_CANFA (Q6QMY5), ERR1_HUMAN (P11474), ERR1_MOUSE (O08580), ERR1_RAT (Q5QJV7), ERR2_HUMAN (O95718), ERR2_MOUSE (Q61539), ERR2_RAT (P11475), ERR3_HUMAN (P62508), ERR3_MOUSE (P62509), ERR3_PONAB (Q5RAM2), ERR3_RAT (P62510), ESR1_BOVIN (P49884), ESR1_CHICK (P06212), ESR1_DANRE (P57717), ESR1_FELCA (Q53AD2), ESR1_HORSE (Q9TV98), ESR1_HUMAN (P03372), ESR1_ICTPU (Q9YHZ7), ESR1_MESAU (Q9QZJ5), ESR1_MOUSE (P19785), ESR1_ONCMY (P16058), ESR1_OREAU (P50240), ESR1_ORENI (Q9YH33), ESR1_ORYLA (P50241), ESR1_PAGMA (O42132), ESR1_PIG (Q29040), ESR1_RAT (P06211), ESR1_SALSA (P50242), ESR1_SHEEP (P49885), ESR1_SPAAU (Q9PVZ9), ESR1_TAEGU (Q91250), ESR1_XENLA (P81559), ESR21_CARAU (Q9W669), ESR22_CARAU (Q9IAL9), ESR2_ANGJA (O13012), ESR2_BOVIN (Q9XSB5), ESR2_CALJA (Q95171), ESR2_CHICK (Q9PTU5), ESR2_COTJA (O93511), ESR2_HUMAN (Q92731), ESR2_ICTPU (Q9IAK1), ESR2_MICUN (P57781), ESR2_MOUSE (O08537), ESR2_ONCMY (P57782), ESR2_ORENI (Q9YH32), ESR2_PIG (Q9XSW2), ESR2_RAT (Q62986), ESR2_SHEEP (Q9TU15), ESR2_SPAAU (Q9W6M2), ESR2_STUVU (Q9PVE2), ESR3_MICUN (P57783), FTF1B_DROME (Q05192), FTZF1_BOMMO (P49867), FTZF1_DROME (P33244), GAG_AVIER (P03373), GCNFA_DANRE (Q9PU65), GCNFB_DANRE (Q4V8R7), GCR_AOTNA (P79686), GCR_CALJA (Q6XLJ0), GCR_CAVPO (P49115), GCR_HUMAN (P04150), GCR_MOUSE (P06537), GCR_ONCMY (P49843), GCR_PAROL (O73673), GCR_PIG (Q9N1U3), GCR_PONAB (Q5R9P5), GCR_RABIT (P59667), GCR_RAT (P06536), GCR_SAGOE (P79269), GCR_SAIBB (O13186), GCR_SAISC (O46567), GCR_SHEEP (P35547), GCR_TUPBE (Q95267), GCR_XENLA (P49844), HNF4A_HUMAN (P41235), HNF4A_MOUSE (P49698), HNF4A_RAT (P22449), HNF4A_XENLA (Q91766), HNF4B_XENLA (P79926), HNF4G_HUMAN (Q14541), HNF4G_MOUSE (Q9WUU6), HNF4_DROME (P49866), HR38_BOMMO (P49870), HR38_DROME (P49869), HR3_DROME (P31396), HR3_GALME (P49868), HR3_MANSE (Q08882), HR4_DROME (Q9W539), HR78_DROME (Q24142), HR96_DROME (Q24143), KNIR_DROME (P10734), KNIR_DROVI (Q24753), KNRL_DROME (P13054), MCR_AOTNA (Q3YC04), MCR_HUMAN (P08235), MCR_MOUSE (Q8VII8), MCR_RAT (P22199), MCR_SAIBB (Q4JM28), MCR_SAISC (Q9N0W8), MCR_TUPBE (Q29131), MCR_XENLA (Q91573), N2C1A_XENLA (Q6GN21), N2C1B_XENLA (Q66J63), N2F1A_DANRE (Q06725), N2F1B_DANRE (Q6PH18), NH100_CAEEL (O17611), NH103_CAEEL (O16359), NH106_CAEEL (O16966), NH111_CAEEL (O45521), NH115_CAEEL (O16662), NH121_CAEEL (Q9TZ99), NH124_CAEEL (O16391), NH125_CAEEL (O17082), NH127_CAEEL (O18087), NH133_CAEEL (O16354), NH134_CAEEL (O16361), NH136_CAEEL (O01930), NH150_CAEEL (O17573), NH153_CAEEL (O01929), NH154_CAEEL (O01931), NH164_CAEEL (O17657), NH169_CAEEL (O17706), NH174_CAEEL (O17748), NH217_CAEEL (O02305), NH268_CAEEL (O17930), NHR10_CAEEL (P41999), NHR11_CAEEL (Q23294), NHR12_CAEEL (Q21701), NHR13_CAEEL (Q9N4Q7), NHR14_CAEEL (O02151), NHR16_CAEEL (Q27521), NHR18_CAEEL (O16360), NHR19_CAEEL (Q09528), NHR1_CAEEL (Q21878), NHR1_ONCVO (Q25604), NHR20_CAEEL (Q09565), NHR22_CAEEL (Q09587), NHR23_CAEEL (P41828), NHR25_CAEEL (Q19345), NHR28_CAEBR (A8XNK6), NHR28_CAEEL (Q17905), NHR31_CAEEL (Q18192), NHR34_CAEEL (Q21006), NHR35_CAEEL (Q17771), NHR3_CAEEL (Q9XTJ4), NHR40_CAEEL (Q22127), NHR41_CAEEL (Q9N4B8), NHR42_CAEEL (O76828), NHR44_CAEEL (Q22555), NHR47_CAEEL (Q17370), NHR48_CAEEL (Q94407), NHR49_CAEEL (O45666), NHR4_CAEEL (O45436), NHR52_CAEEL (O17928), NHR53_CAEEL (O17933), NHR54_CAEEL (O45460), NHR55_CAEEL (O16962), NHR57_CAEEL (O16425), NHR59_CAEEL (Q9TXJ1), NHR5_CAEEL (Q9NA51), NHR61_CAEEL (O62389), NHR62_CAEEL (O02279), NHR64_CAEEL (O44960), NHR65_CAEEL (O45907), NHR67_CAEEL (Q9XVV3), NHR69_CAEEL (P91829), NHR6_CAEEL (P41829), NHR71_CAEEL (Q9GTD4), NHR75_CAEEL (O16604), NHR77_CAEEL (O02316), NHR79_CAEEL (O18141), NHR7_CAEEL (Q20765), NHR85_CAEEL (Q9XUK7), NHR86_CAEEL (Q965W2), NHR89_CAEEL (O02235), NHR8_CAEEL (Q9XYB7), NHR90_CAEEL (O17025), NHR91_CAEEL (Q9U2R6), NHR96_CAEEL (Q95X91), NHR97_CAEEL (Q9BJK5), NHR98_CAEEL (Q966I0), NHR9_CAEEL (Q23489), NR1D1_BOVIN (Q08E02), NR1D1_HUMAN (P20393), NR1D1_MOUSE (Q3UV55), NR1D1_RAT (Q63503), NR1D1_SHEEP (B3SV56), NR1D2_HUMAN (Q14995), NR1D2_MOUSE (Q60674), NR1D2_RAT (Q63504), NR1H2_BOVIN (Q5BIS6), NR1H2_HUMAN (P55055), NR1H2_MOUSE (Q60644), NR1H2_RAT (Q62755), NR1H3_BOVIN (Q5E9B6), NR1H3_HUMAN (Q13133), NR1H3_MOUSE (Q9Z0Y9), NR1H3_RAT (Q62685), NR1H4_BOVIN (Q3SZL0), NR1H4_HUMAN (Q96RI1), NR1H4_MOUSE (Q60641), NR1H4_RAT (Q62735), NR1I2_HUMAN (O75469), NR1I2_MACMU (Q8SQ01), NR1I2_MOUSE (O54915), NR1I2_RAT (Q9R1A7), NR1I3_CALUR (P62044), NR1I3_HUMAN (Q14994), NR1I3_MACMU (Q8MIM3), NR1I3_MOUSE (O35627), NR1I3_PANTR (A2T7D9), NR1I3_PHOSI (P62045), NR1I3_RAT (Q9QUS1), NR2C1_BOVIN (A0JNE3), NR2C1_HUMAN (P13056), NR2C1_MACFA (Q95K90), NR2C1_MOUSE (Q505F1), NR2C1_PONAB (Q5RCZ5), NR2C1_RAT (Q8VIJ4), NR2C1_XENTR (Q28CK1), NR2C2_HUMAN (P49116), NR2C2_MOUSE (P49117), NR2C2_RAT (P55094), NR2E1_CHICK (Q91379), NR2E1_HUMAN (Q9Y466), NR2E1_MOUSE (Q64104), NR2E1_ORYLA (Q9YGL3), NR2E1_XENLA (P70052), NR2E3_BOVIN (Q9TTF0), NR2E3_HUMAN (Q9Y5X4), NR2E3_MOUSE (Q9QXZ7), NR2F5_DANRE (Q06726), NR2F6_HUMAN (P10588), NR2F6_MOUSE (P43136), NR2F6_RAT (O09017), NR4A1_BOVIN (Q0V8F0), NR4A1_CANFA (P51666), NR4A1_HUMAN (P22736), NR4A1_MOUSE (P12813), NR4A1_RAT (P22829), NR4A1_XENLA (Q04913), NR4A2_BOVIN (Q08E53), NR4A2_HUMAN (P43354), NR4A2_MOUSE (Q06219), NR4A2_PONAB (Q5R5Y4), NR4A2_RAT (Q07917), NR4A2_XENTR (A4IIG7), NR4A3_HUMAN (Q92570), NR4A3_MOUSE (Q9QZB6), NR4A3_RAT (P51179), NR5A2_CHICK (O42101), NR5A2_HUMAN (O00482), NR5A2_MOUSE (P45448), NR5A2_RAT (Q9QWM1), NR6A1_HUMAN (Q15406), NR6A1_MOUSE (Q64249), NR6A1_PIG (A0P8Z4), NR6A1_XENLA (P70033), NR6A1_XENTR (Q66JK1), ODR7_CAEEL (P41933), PPARA_CANFA (Q95N78), PPARA_CAVPO (O35507), PPARA_HUMAN (Q07869), PPARA_MOUSE (P23204), PPARA_PHACI (Q8HYL6), PPARA_RAT (P37230), PPARA_XENLA (P37232), PPARD_CANFA (Q0ZAQ8), PPARD_HUMAN (Q03181), PPARD_MOUSE (P35396), PPARD_XENLA (P37233), PPARG_BOVIN (O18971), PPARG_CANFA (Q4U3Q4), PPARG_CRIGR (P57797), PPARG_HUMAN (P37231), PPARG_MACMU (O18924), PPARG_MOUSE (P37238), PPARG_PIG (O62807), PPARG_RABIT (O19052), PPARG_RAT (O88275), PPARG_XENLA (P37234), PRGR_ATEPA (A7XW25), PRGR_CANFA (Q9GLW0), PRGR_CEBAP (A7XW16), PRGR_CHICK (P07812), PRGR_CHLAE (A7X8C9), PRGR_COLGU (A7X8D2), PRGR_GORGO (A7X8B7), PRGR_HUMAN (P06401), PRGR_HYLLA (A7X8C2), PRGR_MACSY (A7X8C4), PRGR_MOUSE (Q00175), PRGR_PANPA (A7X8B5), PRGR_PANTR (A7X8B3), PRGR_PAPAN (A7X8C7), PRGR_PITIR (A7XW20), PRGR_PONPY (A7X8B9), PRGR_RABIT (P06186), PRGR_RANDY (Q8AYI2), PRGR_RAT (Q63449), PRGR_SHEEP (Q28590), PRGR_TRAOB (A7X8D4), RARAA_DANRE (Q90271), RARAB_DANRE (Q7ZTI3), RARA_CANFA (Q5FBR4), RARA_CHICK (Q90966), RARA_HUMAN (P10276), RARA_MOUSE (P11416), RARA_NOTVI (P18514), RARA_TAKRU (Q9W5Z3), RARA_XENLA (P51126), RARB_CHICK (P22448), RARB_COTJA (Q9W6B3), RARB_HUMAN (P10826), RARB_MOUSE (P22605), RARB_NOTVI (P18515), RARGA_DANRE (Q91392), RARGB_DANRE (A2T928), RARG_HUMAN (P13631), RARG_MOUSE (P18911), RARG_NOTVI (P18516), RARG_XENLA (P28699), RORA_HUMAN (P35398), RORA_MOUSE (P51448), RORB_HUMAN (Q92753), RORB_MOUSE (Q8R1B8), RORB_RAT (P45446), RORG_HUMAN (P51449), RORG_MOUSE (P51450), RORG_PONAB (Q5RAP4), RXRAA_DANRE (A2T929), RXRAB_DANRE (Q90415), RXRA_HUMAN (P19793), RXRA_MOUSE (P28700), RXRA_RAT (Q05343), RXRA_XENLA (P51128), RXRBA_DANRE (Q7SYN5), RXRBB_DANRE (Q90417), RXRB_CANFA (Q5TJF7), RXRB_HUMAN (P28702), RXRB_MOUSE (P28704), RXRB_RAT (P49743), RXRGA_DANRE (Q90416), RXRGB_DANRE (Q6DHP9), RXRG_BOVIN (Q0VC20), RXRG_CHICK (P28701), RXRG_HUMAN (P48443), RXRG_MOUSE (P28705), RXRG_PIG (Q0GFF6), RXRG_PONAB (Q5REL6), RXRG_RAT (Q5BJR8), RXRG_XENLA (P51129), RXR_BIOGL (Q8T5C6), RXR_LYMST (Q5I7G2), SHR2_STRPU (Q26622), STF1_BOVIN (Q04752), STF1_HORSE (Q9GKL2), STF1_HUMAN (Q13285), STF1_MACEU (Q95L87), STF1_MOUSE (P33242), STF1_PIG (P79387), STF1_RAT (P50569), THAA_DANRE (Q98867), THAA_PAROL (Q91241), THAA_XENLA (P15204), THAB_PAROL (Q91242), THAB_XENLA (P18115), THA_APTPA (O42295), THA_CAIMO (Q90382), THA_CHICK (P04625), THA_HIPHI (Q9W6N4), THA_HUMAN (P10827), THA_LITCT (Q02777), THA_MOUSE (P63058), THA_NECMA (O57606), THA_PIG (O97716), THA_PYGAD (O42450), THA_RAT (P63059), THA_SALSA (Q9W785), THA_SHEEP (Q28570), THBA_XENLA (P18117), THBB_XENLA (P18119), THB_CAIMO (P68305), THB_CHICK (P68306), THB_DANRE (Q9PVE4), THB_HUMAN (P10828), THB_LITCT (Q02965), THB_MOUSE (P37242), THB_PAROL (Q91279), THB_RAT (P18113), THB_SHEEP (Q28571), TLL_DROME (P18102), TLL_DROVI (O16845), USP_BOMMO (P49700), USP_CHOFU (O76202), USP_DROME (P20153), USP_MANSE (P54779), VDRA_DANRE (Q9PTN2), VDRB_DANRE (Q1L673), VDR_BOVIN (Q28037), VDR_CHICK (O42392), VDR_COTJA (P49701), VDR_HUMAN (P11473), VDR_MOUSE (P48281), VDR_PIG (A3RGC1), VDR_RAT (P13053), VDR_SAGOE (Q95MH5), VDR_XENLA (O13124)False negative hits (sequences which belong to the set under consideration, but which have not been picked up by the pattern or profile): NH108_CAEEL (O45449), NH130_CAEEL (O16963), NH167_CAEEL (O17683), NH197_CAEEL (O17931), NH199_CAEEL (O17934), NH213_CAEEL (O18048), NH218_CAEEL (O18086), NHR2_CAEEL (Q10902), NHR51_CAEEL (O17927)`Potential' hits (partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences): ESR1_ANOCA (Q9YHT3), ESR1_ASPUN (Q91424), ESR1_MACMU (P49886), ESR1_MICUN (P57753), ESR2_MACMU (Q9TTE5), PRGR_MACEU (P79373), THA_ELECQ (Q9PUA8), THA_ONCMY (Q9W6I9), THA_SPAAU (O57568)Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits: [Clustal format, color, condensed view]
[Clustal format, color]
[Clustal format, plain text]
[Fasta format]
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| PDB [Detailed view] |
1A6Y; 1BY4; 1CIT; 1DSZ; 1GA5; 1GDC; 1GLU; 1HCP; 1HCQ; 1HLZ; 1HRA; 1KB2; 1KB4; 1KB6; 1LAT; 1LO1; 1R0N; 1R0O; 1R4I; 1R4O; 1R4R; 1RGD; 1RXR; 1YNW; 2A66; 2C7A; 2EBL; 2ENV; 2FF0; 2GDA; 2HAN; 2NLL; 3CBB; 3DZU; 3DZY; 3E00; 3FYL; 3G6P; 3G6Q; 3G6R; 3G6T; 3G6U; 3G8U; 3G8X; 3G97; 3G99; 3G9I; 3G9J; 3G9M; 3G9O; 3G9P; 3M9E; 4AA6; 4HN5; 4HN6; |
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