Entry: PS00046

General information about the entry

Entry name [info] HISTONE_H2A
Accession [info] PS00046
Entry type [info] PATTERN
Date [info] APR-1990 (CREATED); NOV-1995 (DATA UPDATE); JUN-2016 (INFO UPDATE).
PROSITE Doc. [info] PDOC00045

Name and characterization of the entry

Description [info] Histone H2A signature.
Pattern [info]
[AC]-G-L-x-F-P-V.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2016_07 which contains 551'705 sequence entries.


Total number of hits 221 in 221 different sequences
Number of true positive hits 216 in 216 different sequences
Number of 'unknown' hits 0
Number of false positive hits 5 in 5 different sequences
Number of false negative sequences 17
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 97.74 %
Recall (true positives / (true positives + false negatives)) 92.70 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
216 sequences

H2A1A_HUMAN (Q96QV6    ), H2A1B_HUMAN (P04908    ), H2A1C_HUMAN (Q93077    ), 
H2A1C_RAT   (P0C169    ), H2A1D_HUMAN (P20671    ), H2A1E_RAT   (P0C170    ), 
H2A1F_MOUSE (Q8CGP5    ), H2A1F_RAT   (Q64598    ), H2A1H_HUMAN (Q96KK5    ), 
H2A1H_MOUSE (Q8CGP6    ), H2A1J_HUMAN (Q99878    ), H2A1K_MOUSE (Q8CGP7    ), 
H2A1_ARATH  (Q9C681    ), H2A1_ASHGO  (Q74ZL4    ), H2A1_BOVIN  (P0C0S9    ), 
H2A1_CANAL  (Q59SU5    ), H2A1_CANGA  (Q6FWM7    ), H2A1_DEBHA  (Q6BKW8    ), 
H2A1_HUMAN  (P0C0S8    ), H2A1_LEIIN  (P27891    ), H2A1_LODEL  (A5DWF1    ), 
H2A1_MEDTR  (Q2HU68    ), H2A1_MOUSE  (P22752    ), H2A1_ORYSI  (A2YMC5    ), 
H2A1_ORYSJ  (Q6ZL43    ), H2A1_PEA    (P25470    ), H2A1_PICGU  (A5DBG4    ), 
H2A1_PICST  (A3LZZ0    ), H2A1_PSAMI  (P04735    ), H2A1_RAT    (P02262    ), 
H2A1_SCHPO  (P04909    ), H2A1_SOLLC  (P25469    ), H2A1_TETPY  (P02274    ), 
H2A1_TETTS  (P35065    ), H2A1_WHEAT  (P02275    ), H2A1_XENLA  (P06897    ), 
H2A1_YEAST  (P04911    ), H2A2A_HUMAN (Q6FI13    ), H2A2A_MOUSE (Q6GSS7    ), 
H2A2A_RAT   (P0CC09    ), H2A2B_HUMAN (Q8IUE6    ), H2A2B_MOUSE (Q64522    ), 
H2A2C_BOVIN (A1A4R1    ), H2A2C_HUMAN (Q16777    ), H2A2C_MOUSE (Q64523    ), 
H2A2_ARATH  (Q9LHQ5    ), H2A2_ASHGO  (Q757L4    ), H2A2_CANAL  (Q59VP2    ), 
H2A2_CANGA  (Q6FM31    ), H2A2_DEBHA  (Q6BRG3    ), H2A2_LEIIN  (P27892    ), 
H2A2_LODEL  (A5DXS8    ), H2A2_MEDTR  (Q2HU65    ), H2A2_ORYSI  (A2YMC6    ), 
H2A2_ORYSJ  (Q6ZL42    ), H2A2_PEA    (P40281    ), H2A2_PICGU  (A5DJJ2    ), 
H2A2_PICST  (A3LXE7    ), H2A2_PSAMI  (P04736    ), H2A2_SCHPO  (P04910    ), 
H2A2_WHEAT  (P02276    ), H2A2_XENLA  (P06898    ), H2A2_YEAST  (P04912    ), 
H2A3_ARATH  (O81826    ), H2A3_CHICK  (P35062    ), H2A3_HUMAN  (Q7L7L0    ), 
H2A3_LYTPI  (P09589    ), H2A3_MEDTR  (Q1S053    ), H2A3_MOUSE  (Q8BFU2    ), 
H2A3_ORYSI  (A2YVE5    ), H2A3_ORYSJ  (Q84NJ4    ), H2A3_PSAMI  (P69139    ), 
H2A3_RAT    (Q4FZT6    ), H2A3_STRPU  (P09590    ), H2A3_VOLCA  (P16865    ), 
H2A3_WHEAT  (P02277    ), H2A4_CHICK  (P02263    ), H2A4_ORYSI  (A2Y5G8    ), 
H2A4_ORYSJ  (Q6L500    ), H2A4_PSAMI  (P07793    ), H2A4_RAT    (Q00728    ), 
H2A4_VOLCA  (P16866    ), H2A4_WHEAT  (Q43208    ), H2A5_ARATH  (Q94F49    ), 
H2A5_ORYSI  (A2WQG7    ), H2A5_ORYSJ  (Q94E96    ), H2A5_WHEAT  (Q43213    ), 
H2A6_ARATH  (Q9LD28    ), H2A6_ORYSI  (A2XZN0    ), H2A6_ORYSJ  (Q75L11    ), 
H2A6_WHEAT  (Q43214    ), H2A7_ARATH  (Q9FJE8    ), H2A7_ORYSI  (A2ZK29    ), 
H2A7_ORYSJ  (Q2QS71    ), H2A7_WHEAT  (Q43312    ), H2AE_PSAMI  (P69142    ), 
H2AJ_BOVIN  (Q3ZBX9    ), H2AJ_CHICK  (P70082    ), H2AJ_HUMAN  (Q9BTM1    ), 
H2AJ_MACFA  (Q4R3X5    ), H2AJ_MOUSE  (Q8R1M2    ), H2AJ_RAT    (A9UMV8    ), 
H2AL_STRPU  (P16886    ), H2AO_CHITH  (Q07135    ), H2AV1_ORYSJ (Q8H7Y8    ), 
H2AV3_ARATH (Q9C944    ), H2AV3_ORYSJ (Q84MP7    ), H2AV_BOVIN  (Q32LA7    ), 
H2AV_CAEEL  (Q27511    ), H2AV_CHICK  (P02272    ), H2AV_DANRE  (Q71PD7    ), 
H2AV_DROME  (P08985    ), H2AV_HUMAN  (Q71UI9    ), H2AV_MOUSE  (Q3THW5    ), 
H2AV_PAGMA  (Q6Y237    ), H2AV_RABIT  (O62695    ), H2AV_STRPU  (P08991    ), 
H2AV_TETTS  (P08992    ), H2AV_XENLA  (Q6GM74    ), H2AV_XENTR  (Q5BJ65    ), 
H2AXA_ARATH (O04848    ), H2AXA_ORYSI (A2XLI0    ), H2AXA_ORYSJ (Q8LLP5    ), 
H2AXB_ARATH (Q9S9K7    ), H2AXB_ORYSI (A2ZL69    ), H2AXB_ORYSJ (Q2QPG9    ), 
H2AX_CICAR  (O65759    ), H2AX_DANRE  (Q7ZUY3    ), H2AX_HUMAN  (P16104    ), 
H2AX_MOUSE  (P27661    ), H2AX_PICAB  (P35063    ), H2AX_TETPY  (P02273    ), 
H2AX_TETTS  (P35064    ), H2AX_XENLA  (Q6GM86    ), H2AZL_XENLA (P70094    ), 
H2AZL_XENTR (Q6DER6    ), H2AZ_ASHGO  (Q75CC6    ), H2AZ_BOVIN  (P0C0S4    ), 
H2AZ_CANAL  (Q5AEE1    ), H2AZ_CHICK  (Q5ZMD6    ), H2AZ_CRYNB  (P0CO01    ), 
H2AZ_CRYNJ  (P0CO00    ), H2AZ_DEBHA  (Q6BQE9    ), H2AZ_DICDI  (Q54LA5    ), 
H2AZ_HUMAN  (P0C0S5    ), H2AZ_KLULA  (Q6CUC8    ), H2AZ_LODEL  (A5DXC6    ), 
H2AZ_MOUSE  (P0C0S6    ), H2AZ_ONCMY  (P22647    ), H2AZ_PICGU  (A5DQL2    ), 
H2AZ_PICST  (A3GHC1    ), H2AZ_PONAB  (Q5RC42    ), H2AZ_RAT    (P0C0S7    ), 
H2AZ_SCHPO  (P48003    ), H2AZ_SHEEP  (Q6YNC8    ), H2AZ_USTMA  (Q4PHE4    ), 
H2AZ_YARLI  (Q6C341    ), H2AZ_YEAST  (Q12692    ), H2A_ACRFO   (P35061    ), 
H2A_AGABI   (Q9HGX4    ), H2A_ASPCL   (A1CJ10    ), H2A_ASPFU   (Q4WWC6    ), 
H2A_ASPNC   (P0C953    ), H2A_ASPNG   (P0C952    ), H2A_ASPOR   (Q2U5A8    ), 
H2A_ASPTN   (Q0CBD2    ), H2A_ASTRU   (P02269    ), H2A_BOTFB   (O74268    ), 
H2A_BUFGR   (P55897    ), H2A_CAEEL   (P09588    ), H2A_CAIMO   (P13912    ), 
H2A_CHAGB   (Q2HH37    ), H2A_CHITH   (P21896    ), H2A_CHLRE   (P50567    ), 
H2A_COCIM   (Q1E5N1    ), H2A_CRYNB   (P0CN99    ), H2A_CRYNJ   (P0CN98    ), 
H2A_DROER   (P84052    ), H2A_DROHY   (P84053    ), H2A_DROME   (P84051    ), 
H2A_DROSI   (P84054    ), H2A_DROYA   (P84055    ), H2A_EMENI   (P08844    ), 
H2A_EUGGR   (P40279    ), H2A_EUPCP   (C0HJB7    ), H2A_EUPES   (Q9M531    ), 
H2A_GIBZE   (Q4HTT1    ), H2A_HIPHI   (P59890    ), H2A_KLULA   (Q6CK59    ), 
H2A_LITVA   (Q6PV61    ), H2A_MAGO7   (P0CT12    ), H2A_MAGOY   (L7HZV6    ), 
H2A_MAIZE   (P40280    ), H2A_MYTCA   (Q6WV66    ), H2A_MYTCH   (Q6WV69    ), 
H2A_MYTED   (Q8I0T3    ), H2A_MYTGA   (Q6WV88    ), H2A_MYTTR   (Q6WV67    ), 
H2A_NEOFI   (A1D8G8    ), H2A_NEUCR   (Q8X132    ), H2A_ONCMY   (P02264    ), 
H2A_PARAN   (P69140    ), H2A_PARLI   (P13630    ), H2A_PETCR   (P19177    ), 
H2A_PHANO   (Q0U1A1    ), H2A_PLADU   (P19178    ), H2A_PLAFA   (P40282    ), 
H2A_PODAS   (Q875B8    ), H2A_RHYAM   (P84056    ), H2A_SEPOF   (P02268    ), 
H2A_SIPNU   (P02270    ), H2A_STRPU   (P69141    ), H2A_TIGCA   (P84057    ), 
H2A_TRYCR   (P35066    ), H2A_URECA   (P27325    ), H2A_USTMA   (Q4PEF9    )
» more

UniProtKB/Swiss-Prot
False negative sequences
17 sequences

H2A4_ARATH  (Q9LZ46    ), H2A8_ORYSI  (A2ZK26    ), H2AB1_HUMAN (P0C5Y9    ), 
H2AB2_HUMAN (P0C5Z0    ), H2AV1_ARATH (O23628    ), H2AV1_DICDI (Q54HW2    ), 
H2AV2_ARATH (Q9SII0    ), H2AV2_DICDI (Q54HV9    ), H2AV2_ORYSJ (Q8S857    ), 
H2AV3_DICDI (Q54HV7    ), H2AX_DICDI  (Q54WG6    ), H2AZ_ASPFU  (Q4WE68    ), 
H2AZ_EMENI  (Q5AUJ1    ), H2AZ_GIBZE  (Q4IMD1    ), H2AZ_NEUCR  (Q873G4    ), 
H2A_ENCCU   (Q8SSG3    ), H2A_YARLI   (Q6C4I6    )
» more

UniProtKB/Swiss-Prot
'Partial' sequences
1 sequence

H2A_OLILU   (P82897    )

		
UniProtKB/Swiss-Prot
False positive sequences
5 sequences

CBH_CLOPE   (P54965    ), COXX_HYPNA  (Q0C3D1    ), MCD4_ASPFU  (Q4W9R7    ), 
NU6M_ALBCA  (P48922    ), Y070_ANAMM  (Q5PBU4    )
» more

PDB
[Detailed view]
124 PDB

1AOI; 1EQZ; 1F66; 1HIO; 1HQ3; 1ID3; 1KX3; 1KX4; 1KX5; 1M18; 1M19; 1M1A; 1P34; 1P3A; 1P3B; 1P3F; 1P3G; 1P3I; 1P3K; 1P3L; 1P3M; 1P3O; 1P3P; 1S32; 1TZY; 1ZBB; 1ZLA; 2ARO; 2CV5; 2F8N; 2FJ7; 2HIO; 2JSS; 2NQB; 2NZD; 2PYO; 2RVQ; 2XQL; 3A6N; 3AFA; 3AN2; 3AV1; 3AV2; 3AYW; 3AZE; 3AZF; 3AZG; 3AZH; 3AZI; 3AZJ; 3AZK; 3AZL; 3AZM; 3AZN; 3B6F; 3B6G; 3C1B; 3C1C; 3C9K; 3KUY; 3KWQ; 3LJA; 3MNN; 3O62; 3REH; 3REI; 3REJ; 3REK; 3REL; 3TU4; 3UT9; 3UTA; 3UTB; 3W96; 3W97; 3W98; 3W99; 3WA9; 3WAA; 3WKJ; 3WTP; 3X1S; 3X1V; 4CAY; 4J8U; 4J8V; 4J8W; 4J8X; 4JJN; 4KUD; 4LD9; 4M6B; 4NFT; 4QLC; 4WNN; 4WU8; 4WU9; 4X23; 4XUJ; 4XZQ; 4YM5; 4YM6; 4YS3; 4Z5T; 4Z66; 4ZUX; 5AV5; 5AV6; 5AV8; 5AV9; 5AVB; 5AVC; 5AY8; 5B0Y; 5B0Z; 5B24; 5CHL; 5CPI; 5CPJ; 5CPK; 5E5A; 5F99; 5FUG; 5HQ2
» more

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