Entry: PS00046

General information about the entry
Entry name HISTONE_H2A
Accession number PS00046
Entry type PATTERN
Date APR-1990 (CREATED); NOV-1995 (DATA UPDATE); APR-2013 (INFO UPDATE).
PROSITE Documentation PDOC00045
Name and characterization of the entry
DescriptionHistone H2A signature.
Pattern [AC]-G-L-x-F-P-V.
Numerical results
  • UniProtKB/Swiss-Prot release number: 2013_06, total number of sequence entries in that release: 540261.
  • Total number of hits in UniProtKB/Swiss-Prot: 219 hits in 219 different sequences
  • Number of hits on proteins that are known to belong to the set under consideration: 214 hits in 214 different sequences
  • Number of hits on proteins that could potentially belong to the set under consideration: 0 hits in 0 different sequences
  • Number of false hits (on unrelated proteins): 5 hits in 5 different sequences
  • Number of known missed hits: 17
  • Number of partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences: 1
  • Precision (true hits / (true hits + false positives)): 97.72 %
  • Recall (true hits / (true hits + false negatives)): 92.64 %
Comments
  • Taxonomic range: Eukaryotes
  • Maximum known number of repetitions of the pattern in a single protein: 1
  • VERSION: 1
Cross-references
UniProtKB/Swiss-Prot True positive hits:
H2A1A_HUMAN (Q96QV6), H2A1B_HUMAN (P04908), H2A1C_HUMAN (Q93077), 
H2A1C_RAT   (P0C169), H2A1D_HUMAN (P20671), H2A1E_RAT   (P0C170), 
H2A1F_MOUSE (Q8CGP5), H2A1F_RAT   (Q64598), H2A1H_HUMAN (Q96KK5), 
H2A1H_MOUSE (Q8CGP6), H2A1J_HUMAN (Q99878), H2A1K_MOUSE (Q8CGP7), 
H2A1_ARATH  (Q9C681), H2A1_ASHGO  (Q74ZL4), H2A1_BOVIN  (P0C0S9), 
H2A1_CANAL  (Q59SU5), H2A1_CANGA  (Q6FWM7), H2A1_DEBHA  (Q6BKW8), 
H2A1_HUMAN  (P0C0S8), H2A1_LEIIN  (P27891), H2A1_LODEL  (A5DWF1), 
H2A1_MEDTR  (Q2HU68), H2A1_MOUSE  (P22752), H2A1_ORYSI  (A2YMC5), 
H2A1_ORYSJ  (Q6ZL43), H2A1_PEA    (P25470), H2A1_PICGU  (A5DBG4), 
H2A1_PICST  (A3LZZ0), H2A1_PSAMI  (P04735), H2A1_RAT    (P02262), 
H2A1_SCHPO  (P04909), H2A1_SOLLC  (P25469), H2A1_TETPY  (P02274), 
H2A1_TETTS  (P35065), H2A1_WHEAT  (P02275), H2A1_XENLA  (P06897), 
H2A1_YEAST  (P04911), H2A2A_HUMAN (Q6FI13), H2A2A_MOUSE (Q6GSS7), 
H2A2A_RAT   (P0CC09), H2A2B_HUMAN (Q8IUE6), H2A2B_MOUSE (Q64522), 
H2A2C_BOVIN (A1A4R1), H2A2C_HUMAN (Q16777), H2A2C_MOUSE (Q64523), 
H2A2_ARATH  (Q9LHQ5), H2A2_ASHGO  (Q757L4), H2A2_CANAL  (Q59VP2), 
H2A2_CANGA  (Q6FM31), H2A2_DEBHA  (Q6BRG3), H2A2_LEIIN  (P27892), 
H2A2_LODEL  (A5DXS8), H2A2_MEDTR  (Q2HU65), H2A2_ORYSI  (A2YMC6), 
H2A2_ORYSJ  (Q6ZL42), H2A2_PEA    (P40281), H2A2_PICGU  (A5DJJ2), 
H2A2_PICST  (A3LXE7), H2A2_PSAMI  (P04736), H2A2_SCHPO  (P04910), 
H2A2_WHEAT  (P02276), H2A2_XENLA  (P06898), H2A2_YEAST  (P04912), 
H2A3_ARATH  (O81826), H2A3_CHICK  (P35062), H2A3_HUMAN  (Q7L7L0), 
H2A3_LYTPI  (P09589), H2A3_MEDTR  (Q1S053), H2A3_MOUSE  (Q8BFU2), 
H2A3_ORYSI  (A2YVE5), H2A3_ORYSJ  (Q84NJ4), H2A3_PSAMI  (P69139), 
H2A3_RAT    (Q4FZT6), H2A3_STRPU  (P09590), H2A3_VOLCA  (P16865), 
H2A3_WHEAT  (P02277), H2A4_CHICK  (P02263), H2A4_ORYSI  (A2Y5G8), 
H2A4_ORYSJ  (Q6L500), H2A4_PSAMI  (P07793), H2A4_RAT    (Q00728), 
H2A4_VOLCA  (P16866), H2A4_WHEAT  (Q43208), H2A5_ARATH  (Q94F49), 
H2A5_ORYSI  (A2WQG7), H2A5_ORYSJ  (Q94E96), H2A5_WHEAT  (Q43213), 
H2A6_ARATH  (Q9LD28), H2A6_ORYSI  (A2XZN0), H2A6_ORYSJ  (Q75L11), 
H2A6_WHEAT  (Q43214), H2A7_ARATH  (Q9FJE8), H2A7_ORYSI  (A2ZK29), 
H2A7_ORYSJ  (Q2QS71), H2A7_WHEAT  (Q43312), H2AE_PSAMI  (P69142), 
H2AJ_BOVIN  (Q3ZBX9), H2AJ_CHICK  (P70082), H2AJ_HUMAN  (Q9BTM1), 
H2AJ_MACFA  (Q4R3X5), H2AJ_MOUSE  (Q8R1M2), H2AJ_RAT    (A9UMV8), 
H2AL_STRPU  (P16886), H2AO_CHITH  (Q07135), H2AV1_ORYSJ (Q8H7Y8), 
H2AV3_ARATH (Q9C944), H2AV3_ORYSJ (Q84MP7), H2AV_BOVIN  (Q32LA7), 
H2AV_CAEEL  (Q27511), H2AV_CHICK  (P02272), H2AV_DANRE  (Q71PD7), 
H2AV_DROME  (P08985), H2AV_HUMAN  (Q71UI9), H2AV_MOUSE  (Q3THW5), 
H2AV_PAGMA  (Q6Y237), H2AV_RABIT  (O62695), H2AV_STRPU  (P08991), 
H2AV_TETTS  (P08992), H2AV_XENLA  (Q6GM74), H2AV_XENTR  (Q5BJ65), 
H2AXA_ARATH (O04848), H2AXA_ORYSI (A2XLI0), H2AXA_ORYSJ (Q8LLP5), 
H2AXB_ARATH (Q9S9K7), H2AXB_ORYSI (A2ZL69), H2AXB_ORYSJ (Q2QPG9), 
H2AX_CICAR  (O65759), H2AX_DANRE  (Q7ZUY3), H2AX_HUMAN  (P16104), 
H2AX_MOUSE  (P27661), H2AX_PICAB  (P35063), H2AX_TETPY  (P02273), 
H2AX_TETTS  (P35064), H2AX_XENLA  (Q6GM86), H2AZL_XENLA (P70094), 
H2AZL_XENTR (Q6DER6), H2AZ_ASHGO  (Q75CC6), H2AZ_BOVIN  (P0C0S4), 
H2AZ_CANAL  (Q5AEE1), H2AZ_CHICK  (Q5ZMD6), H2AZ_CRYNB  (P0CO01), 
H2AZ_CRYNJ  (P0CO00), H2AZ_DEBHA  (Q6BQE9), H2AZ_DICDI  (Q54LA5), 
H2AZ_HUMAN  (P0C0S5), H2AZ_KLULA  (Q6CUC8), H2AZ_LODEL  (A5DXC6), 
H2AZ_MOUSE  (P0C0S6), H2AZ_ONCMY  (P22647), H2AZ_PICGU  (A5DQL2), 
H2AZ_PICST  (A3GHC1), H2AZ_PONAB  (Q5RC42), H2AZ_RAT    (P0C0S7), 
H2AZ_SCHPO  (P48003), H2AZ_SHEEP  (Q6YNC8), H2AZ_USTMA  (Q4PHE4), 
H2AZ_YARLI  (Q6C341), H2AZ_YEAST  (Q12692), H2A_ACRFO   (P35061), 
H2A_AGABI   (Q9HGX4), H2A_ASPCL   (A1CJ10), H2A_ASPFU   (Q4WWC6), 
H2A_ASPNC   (P0C953), H2A_ASPNG   (P0C952), H2A_ASPOR   (Q2U5A8), 
H2A_ASPTN   (Q0CBD2), H2A_ASTRU   (P02269), H2A_BOTFB   (O74268), 
H2A_BUFGR   (P55897), H2A_CAEEL   (P09588), H2A_CAIMO   (P13912), 
H2A_CHAGB   (Q2HH37), H2A_CHITH   (P21896), H2A_CHLRE   (P50567), 
H2A_COCIM   (Q1E5N1), H2A_CRYNB   (P0CN99), H2A_CRYNJ   (P0CN98), 
H2A_DROER   (P84052), H2A_DROHY   (P84053), H2A_DROME   (P84051), 
H2A_DROSI   (P84054), H2A_DROYA   (P84055), H2A_EMENI   (P08844), 
H2A_EUGGR   (P40279), H2A_EUPES   (Q9M531), H2A_GIBZE   (Q4HTT1), 
H2A_HIPHI   (P59890), H2A_KLULA   (Q6CK59), H2A_LITVA   (Q6PV61), 
H2A_MAGO7   (Q5G578), H2A_MAIZE   (P40280), H2A_MYTCA   (Q6WV66), 
H2A_MYTCH   (Q6WV69), H2A_MYTED   (Q8I0T3), H2A_MYTGA   (Q6WV88), 
H2A_MYTTR   (Q6WV67), H2A_NEOFI   (A1D8G8), H2A_NEUCR   (Q8X132), 
H2A_ONCMY   (P02264), H2A_PARAN   (P69140), H2A_PARLI   (P13630), 
H2A_PETCR   (P19177), H2A_PHANO   (Q0U1A1), H2A_PLADU   (P19178), 
H2A_PLAFA   (P40282), H2A_PODAS   (Q875B8), H2A_RHYAM   (P84056), 
H2A_SEPOF   (P02268), H2A_SIPNU   (P02270), H2A_STRPU   (P69141), 
H2A_TIGCA   (P84057), H2A_TRYCR   (P35066), H2A_URECA   (P27325), 
H2A_USTMA   (Q4PEF9)
False negative hits (sequences which belong to the set under consideration, but which have not been picked up by the pattern or profile):
H2A4_ARATH  (Q9LZ46), H2A8_ORYSI  (A2ZK26), H2AB1_HUMAN (P0C5Y9), 
H2AB2_HUMAN (P0C5Z0), H2AV1_ARATH (O23628), H2AV1_DICDI (Q54HW2), 
H2AV2_ARATH (Q9SII0), H2AV2_DICDI (Q54HV9), H2AV2_ORYSJ (Q8S857), 
H2AV3_DICDI (Q54HV7), H2AX_DICDI  (Q54WG6), H2AZ_ASPFU  (Q4WE68), 
H2AZ_EMENI  (Q5AUJ1), H2AZ_GIBZE  (Q4IMD1), H2AZ_NEUCR  (Q873G4), 
H2A_ENCCU   (Q8SSG3), H2A_YARLI   (Q6C4I6)
`Potential' hits (partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences):
H2A_OLILU   (P82897)
False positive hits (sequences which do not belong to the set under consideration):
CBH_CLOPE   (P54965), COXX_HYPNA  (Q0C3D1), MCD4_ASPFU  (Q4W9R7), 
NU6M_ALBCO  (P48922), Y070_ANAMM  (Q5PBU4)
Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:

[Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format]

Retrieve the sequence logo from the alignment

PDB
[Detailed view]
1AOI; 1EQZ; 1F66; 1HIO; 1HQ3; 1ID3; 1KX3; 1KX4; 1KX5; 1M18; 1M19; 1M1A; 1P34; 1P3A; 1P3B; 1P3F; 1P3G; 1P3I; 1P3K; 1P3L; 1P3M; 1P3O; 1P3P; 1S32; 1TZY; 1ZBB; 1ZLA; 2ARO; 2CV5; 2F8N; 2FJ7; 2FSB; 2HIO; 2IR1; 2JSS; 2NQB; 2NZD; 2PYO; 2XQL; 3A6N; 3AFA; 3AN2; 3AV1; 3AV2; 3AYW; 3AZE; 3AZF; 3AZG; 3AZH; 3AZI; 3AZJ; 3AZK; 3AZL; 3AZM; 3AZN; 3B6F; 3B6G; 3C1B; 3C1C; 3C9K; 3KUY; 3KWQ; 3LJA; 3MNN; 3O62; 3REH; 3REI; 3REJ; 3REK; 3REL; 3TU4; 3UT9; 3UTA; 3UTB;

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