Entry: PS00046

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General information about the entry

Entry name [info] HISTONE_H2A
Accession [info] PS00046
Entry type [info] PATTERN
Date [info] APR-1990 (CREATED); NOV-1995 (DATA UPDATE); JUL-2014 (INFO UPDATE).
PROSITE Doc. [info] PDOC00045

Name and characterization of the entry

Description [info] Histone H2A signature.
Pattern [info]
[AC]-G-L-x-F-P-V.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2014_09 which contains 546'439 sequence entries.


Total number of hits 221 in 221 different sequences
Number of true positive hits 216 in 216 different sequences
Number of 'unknown' hits
Number of false positive hits 5 in 5 different sequences
Number of false negative sequences 17
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 97.74 %
Recall (true positives / (true positives + false negatives)) 92.70 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
216 sequences

H2A1A_HUMAN (Q96QV6), H2A1B_HUMAN (P04908), H2A1C_HUMAN (Q93077), 
H2A1C_RAT   (P0C169), H2A1D_HUMAN (P20671), H2A1E_RAT   (P0C170), 
H2A1F_MOUSE (Q8CGP5), H2A1F_RAT   (Q64598), H2A1H_HUMAN (Q96KK5), 
H2A1H_MOUSE (Q8CGP6), H2A1J_HUMAN (Q99878), H2A1K_MOUSE (Q8CGP7), 
H2A1_ARATH  (Q9C681), H2A1_ASHGO  (Q74ZL4), H2A1_BOVIN  (P0C0S9), 
H2A1_CANAL  (Q59SU5), H2A1_CANGA  (Q6FWM7), H2A1_DEBHA  (Q6BKW8), 
H2A1_HUMAN  (P0C0S8), H2A1_LEIIN  (P27891), H2A1_LODEL  (A5DWF1), 
H2A1_MEDTR  (Q2HU68), H2A1_MOUSE  (P22752), H2A1_ORYSI  (A2YMC5), 
H2A1_ORYSJ  (Q6ZL43), H2A1_PEA    (P25470), H2A1_PICGU  (A5DBG4), 
H2A1_PICST  (A3LZZ0), H2A1_PSAMI  (P04735), H2A1_RAT    (P02262), 
H2A1_SCHPO  (P04909), H2A1_SOLLC  (P25469), H2A1_TETPY  (P02274), 
H2A1_TETTS  (P35065), H2A1_WHEAT  (P02275), H2A1_XENLA  (P06897), 
H2A1_YEAST  (P04911), H2A2A_HUMAN (Q6FI13), H2A2A_MOUSE (Q6GSS7), 
H2A2A_RAT   (P0CC09), H2A2B_HUMAN (Q8IUE6), H2A2B_MOUSE (Q64522), 
H2A2C_BOVIN (A1A4R1), H2A2C_HUMAN (Q16777), H2A2C_MOUSE (Q64523), 
H2A2_ARATH  (Q9LHQ5), H2A2_ASHGO  (Q757L4), H2A2_CANAL  (Q59VP2), 
H2A2_CANGA  (Q6FM31), H2A2_DEBHA  (Q6BRG3), H2A2_LEIIN  (P27892), 
H2A2_LODEL  (A5DXS8), H2A2_MEDTR  (Q2HU65), H2A2_ORYSI  (A2YMC6), 
H2A2_ORYSJ  (Q6ZL42), H2A2_PEA    (P40281), H2A2_PICGU  (A5DJJ2), 
H2A2_PICST  (A3LXE7), H2A2_PSAMI  (P04736), H2A2_SCHPO  (P04910), 
H2A2_WHEAT  (P02276), H2A2_XENLA  (P06898), H2A2_YEAST  (P04912), 
H2A3_ARATH  (O81826), H2A3_CHICK  (P35062), H2A3_HUMAN  (Q7L7L0), 
H2A3_LYTPI  (P09589), H2A3_MEDTR  (Q1S053), H2A3_MOUSE  (Q8BFU2), 
H2A3_ORYSI  (A2YVE5), H2A3_ORYSJ  (Q84NJ4), H2A3_PSAMI  (P69139), 
H2A3_RAT    (Q4FZT6), H2A3_STRPU  (P09590), H2A3_VOLCA  (P16865), 
H2A3_WHEAT  (P02277), H2A4_CHICK  (P02263), H2A4_ORYSI  (A2Y5G8), 
H2A4_ORYSJ  (Q6L500), H2A4_PSAMI  (P07793), H2A4_RAT    (Q00728), 
H2A4_VOLCA  (P16866), H2A4_WHEAT  (Q43208), H2A5_ARATH  (Q94F49), 
H2A5_ORYSI  (A2WQG7), H2A5_ORYSJ  (Q94E96), H2A5_WHEAT  (Q43213), 
H2A6_ARATH  (Q9LD28), H2A6_ORYSI  (A2XZN0), H2A6_ORYSJ  (Q75L11), 
H2A6_WHEAT  (Q43214), H2A7_ARATH  (Q9FJE8), H2A7_ORYSI  (A2ZK29), 
H2A7_ORYSJ  (Q2QS71), H2A7_WHEAT  (Q43312), H2AE_PSAMI  (P69142), 
H2AJ_BOVIN  (Q3ZBX9), H2AJ_CHICK  (P70082), H2AJ_HUMAN  (Q9BTM1), 
H2AJ_MACFA  (Q4R3X5), H2AJ_MOUSE  (Q8R1M2), H2AJ_RAT    (A9UMV8), 
H2AL_STRPU  (P16886), H2AO_CHITH  (Q07135), H2AV1_ORYSJ (Q8H7Y8), 
H2AV3_ARATH (Q9C944), H2AV3_ORYSJ (Q84MP7), H2AV_BOVIN  (Q32LA7), 
H2AV_CAEEL  (Q27511), H2AV_CHICK  (P02272), H2AV_DANRE  (Q71PD7), 
H2AV_DROME  (P08985), H2AV_HUMAN  (Q71UI9), H2AV_MOUSE  (Q3THW5), 
H2AV_PAGMA  (Q6Y237), H2AV_RABIT  (O62695), H2AV_STRPU  (P08991), 
H2AV_TETTS  (P08992), H2AV_XENLA  (Q6GM74), H2AV_XENTR  (Q5BJ65), 
H2AXA_ARATH (O04848), H2AXA_ORYSI (A2XLI0), H2AXA_ORYSJ (Q8LLP5), 
H2AXB_ARATH (Q9S9K7), H2AXB_ORYSI (A2ZL69), H2AXB_ORYSJ (Q2QPG9), 
H2AX_CICAR  (O65759), H2AX_DANRE  (Q7ZUY3), H2AX_HUMAN  (P16104), 
H2AX_MOUSE  (P27661), H2AX_PICAB  (P35063), H2AX_TETPY  (P02273), 
H2AX_TETTS  (P35064), H2AX_XENLA  (Q6GM86), H2AZL_XENLA (P70094), 
H2AZL_XENTR (Q6DER6), H2AZ_ASHGO  (Q75CC6), H2AZ_BOVIN  (P0C0S4), 
H2AZ_CANAL  (Q5AEE1), H2AZ_CHICK  (Q5ZMD6), H2AZ_CRYNB  (P0CO01), 
H2AZ_CRYNJ  (P0CO00), H2AZ_DEBHA  (Q6BQE9), H2AZ_DICDI  (Q54LA5), 
H2AZ_HUMAN  (P0C0S5), H2AZ_KLULA  (Q6CUC8), H2AZ_LODEL  (A5DXC6), 
H2AZ_MOUSE  (P0C0S6), H2AZ_ONCMY  (P22647), H2AZ_PICGU  (A5DQL2), 
H2AZ_PICST  (A3GHC1), H2AZ_PONAB  (Q5RC42), H2AZ_RAT    (P0C0S7), 
H2AZ_SCHPO  (P48003), H2AZ_SHEEP  (Q6YNC8), H2AZ_USTMA  (Q4PHE4), 
H2AZ_YARLI  (Q6C341), H2AZ_YEAST  (Q12692), H2A_ACRFO   (P35061), 
H2A_AGABI   (Q9HGX4), H2A_ASPCL   (A1CJ10), H2A_ASPFU   (Q4WWC6), 
H2A_ASPNC   (P0C953), H2A_ASPNG   (P0C952), H2A_ASPOR   (Q2U5A8), 
H2A_ASPTN   (Q0CBD2), H2A_ASTRU   (P02269), H2A_BOTFB   (O74268), 
H2A_BUFGR   (P55897), H2A_CAEEL   (P09588), H2A_CAIMO   (P13912), 
H2A_CHAGB   (Q2HH37), H2A_CHITH   (P21896), H2A_CHLRE   (P50567), 
H2A_COCIM   (Q1E5N1), H2A_CRYNB   (P0CN99), H2A_CRYNJ   (P0CN98), 
H2A_DROER   (P84052), H2A_DROHY   (P84053), H2A_DROME   (P84051), 
H2A_DROSI   (P84054), H2A_DROYA   (P84055), H2A_EMENI   (P08844), 
H2A_EUGGR   (P40279), H2A_EUPCP   (C0HJB7), H2A_EUPES   (Q9M531), 
H2A_GIBZE   (Q4HTT1), H2A_HIPHI   (P59890), H2A_KLULA   (Q6CK59), 
H2A_LITVA   (Q6PV61), H2A_MAGO7   (P0CT12), H2A_MAGOY   (L7HZV6), 
H2A_MAIZE   (P40280), H2A_MYTCA   (Q6WV66), H2A_MYTCH   (Q6WV69), 
H2A_MYTED   (Q8I0T3), H2A_MYTGA   (Q6WV88), H2A_MYTTR   (Q6WV67), 
H2A_NEOFI   (A1D8G8), H2A_NEUCR   (Q8X132), H2A_ONCMY   (P02264), 
H2A_PARAN   (P69140), H2A_PARLI   (P13630), H2A_PETCR   (P19177), 
H2A_PHANO   (Q0U1A1), H2A_PLADU   (P19178), H2A_PLAFA   (P40282), 
H2A_PODAS   (Q875B8), H2A_RHYAM   (P84056), H2A_SEPOF   (P02268), 
H2A_SIPNU   (P02270), H2A_STRPU   (P69141), H2A_TIGCA   (P84057), 
H2A_TRYCR   (P35066), H2A_URECA   (P27325), H2A_USTMA   (Q4PEF9)
» More

UniProtKB/Swiss-Prot
False negative sequences
17 sequences

H2A4_ARATH  (Q9LZ46), H2A8_ORYSI  (A2ZK26), H2AB1_HUMAN (P0C5Y9), 
H2AB2_HUMAN (P0C5Z0), H2AV1_ARATH (O23628), H2AV1_DICDI (Q54HW2), 
H2AV2_ARATH (Q9SII0), H2AV2_DICDI (Q54HV9), H2AV2_ORYSJ (Q8S857), 
H2AV3_DICDI (Q54HV7), H2AX_DICDI  (Q54WG6), H2AZ_ASPFU  (Q4WE68), 
H2AZ_EMENI  (Q5AUJ1), H2AZ_GIBZE  (Q4IMD1), H2AZ_NEUCR  (Q873G4), 
H2A_ENCCU   (Q8SSG3), H2A_YARLI   (Q6C4I6)
» More

UniProtKB/Swiss-Prot
'Partial' sequences
1 sequence

H2A_OLILU   (P82897)

		
UniProtKB/Swiss-Prot
False positive sequences
5 sequences

CBH_CLOPE   (P54965), COXX_HYPNA  (Q0C3D1), MCD4_ASPFU  (Q4W9R7), 
NU6M_ALBCA  (P48922), Y070_ANAMM  (Q5PBU4)
» More

PDB
[Detailed view]
90 PDB

1AOI; 1EQZ; 1F66; 1HIO; 1HQ3; 1ID3; 1KX3; 1KX4; 1KX5; 1M18; 1M19; 1M1A; 1P34; 1P3A; 1P3B; 1P3F; 1P3G; 1P3I; 1P3K; 1P3L; 1P3M; 1P3O; 1P3P; 1S32; 1TZY; 1ZBB; 1ZLA; 2ARO; 2CV5; 2F8N; 2FJ7; 2HIO; 2JSS; 2NQB; 2NZD; 2PYO; 2XQL; 3A6N; 3AFA; 3AN2; 3AV1; 3AV2; 3AYW; 3AZE; 3AZF; 3AZG; 3AZH; 3AZI; 3AZJ; 3AZK; 3AZL; 3AZM; 3AZN; 3B6F; 3B6G; 3C1B; 3C1C; 3C9K; 3KUY; 3KWQ; 3LJA; 3MNN; 3O62; 3REH; 3REI; 3REJ; 3REK; 3REL; 3TU4; 3UT9; 3UTA; 3UTB; 3W96; 3W97; 3W98; 3W99; 3WA9; 3WAA; 3WKJ; 4CAY; 4INM; 4J8U; 4J8V; 4J8W; 4J8X; 4JJN; 4KUD; 4LD9; 4M6B; 4NFT
» More

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