Entry: PS00060
General information about the entry
Entry nameADH_IRON_2
Accession numberPS00060
Entry typePATTERN
DateAPR-1990 (CREATED); NOV-1995 (DATA UPDATE); DEC-2011 (INFO UPDATE).
PROSITE DocumentationPDOC00059
Name and characterization of the entry
DescriptionIron-containing alcohol dehydrogenases signature 2.
Pattern[GSW]-x-[LIVTSACD]-[GH]-x(2)-[GSAE]-[GSHYQ]-x-[LIVTP]-[GAST]-[GAS]-x(3)- [LIVMT]-x-[HNS]-[GA]-x-[GTAC].
Numerical results
  • UniProtKB/Swiss-Prot release number: 01, total number of sequence entries in that release: 534242.
  • Total number of hits in UniProtKB/Swiss-Prot: 33 hits in 33 different sequences
  • Number of hits on proteins that are known to belong to the set under consideration: 31 hits in 31 different sequences
  • Number of hits on proteins that could potentially belong to the set under consideration: 0 hits in 0 different sequences
  • Number of false hits (on unrelated proteins): 2 hits in 2 different sequences
  • Number of known missed hits: 26
  • Number of partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences: 1
  • Precision (true hits / (true hits + false positives)): 93.94 %
  • Recall (true hits / (true hits + false negatives)): 54.39 %
Comments
  • Taxonomic range: Eukaryotes, Prokaryotes (Bacteria)
  • Maximum known number of repetitions of the pattern in a single protein: 1
  • VERSION: 1
Cross-references
UniProtKB/Swiss-ProtTrue positive hits:
4HDB_CLOK5  (P38945), ADH1_CLOSA  (P13604), ADH2_ECOLI  (P37686), 
ADH2_ENTHI  (Q24803), ADH2_ZYMMA  (F8DVL8), ADH2_ZYMMO  (P0DJA2), 
ADH3_ENTHI  (Q24857), ADH4_SCHPO  (Q09669), ADH4_YEAS7  (A6ZTT5), 
ADH4_YEAST  (P10127), ADHA_CLOAB  (Q04944), ADHB_CLOAB  (Q04945), 
ADHE_ECO57  (P0A9Q8), ADHE_ECOLI  (P0A9Q7), DHAT_CITFR  (P45513), 
DHAT_KLEPN  (Q59477), EUTG_ECOLI  (P76553), EUTG_SALTY  (P41795), 
FUCO_ECO57  (P0A9S2), FUCO_ECOLI  (P0A9S1), GBSB_BACSU  (P71017), 
GLDA_CITFR  (P45511), GLDA_ECOL6  (P0A9S6), GLDA_ECOLI  (P0A9S5), 
GLDA_GEOSE  (P32816), GLDA_PSEPU  (P50173), GLDA_THEMA  (Q9WYQ4), 
MEDH_BACMT  (P31005), YQHD_ECOLI  (Q46856), YUGJ_BACSU  (O05239), 
YUGK_BACSU  (O05240)
False negative hits (sequences which belong to the set under consideration, but which have not been picked up by the pattern or profile):
ADHE_CLOAB  (P33744), CLCE_PSEAI  (O87612), CLCE_PSESB  (O30847), 
HOT_AEDAE   (Q17EN4), HOT_ANOGA   (Q7Q547), HOT_BOVIN   (A6QP15), 
HOT_CAEBR   (A8WTJ7), HOT_CAEEL   (Q9U2M4), HOT_DICDI   (Q54GJ7), 
HOT_DROME   (Q9W265), HOT_DROPS   (Q28XT3), HOT_HUMAN   (Q8IWW8), 
HOT_MOUSE   (Q8R0N6), HOT_PONAB   (Q5RF11), HOT_RAT     (Q4QQW3), 
HOT_XENLA   (Q08B39), HOT_XENTR   (Q6P371), MACA1_RHOOP (O84992), 
MEDH_RHOER  (Q53062), TCBF_PSESQ  (P27101), TFDF1_CUPPJ (P27137), 
TFDF2_CUPPJ (P94135), TFDF_DELAC  (Q93T12), TFTE_BURCE  (Q45072), 
Y1167_SYNY3 (P74246), YBDH_ECOLI  (P45579)
`Potential' hits (partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences):
MACA2_RHOOP (P56870)
False positive hits (sequences which do not belong to the set under consideration):
CAP2_HUMAN  (P40123), CAP2_PONAB  (Q5R5X8)
Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:

[Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format]

Retrieve the sequence logo from the alignment

PDB
[Detailed view]
1JPU; 1JQ5; 1JQA; 1KQ3; 1OJ7; 1RRM; 2BI4; 2BL4; 3BFJ; 3OWO; 3OX4;

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