Entry: PS00062

Forthcoming changes to the profile format
General information about the entry

Entry name [info] ALDOKETO_REDUCTASE_2
Accession [info] PS00062
Entry type [info] PATTERN
Date [info] APR-1990 (CREATED); DEC-2004 (DATA UPDATE); JUL-2014 (INFO UPDATE).
PROSITE Doc. [info] PDOC00061

Name and characterization of the entry

Description [info] Aldo/keto reductase family signature 2.
Pattern [info]
[LIVMFY]-x(8)-{L}-[KREQ]-{K}-[LIVM]-G-[LIVM]-[SC]-N-[FY].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2014_08 which contains 546'238 sequence entries.


Total number of hits 159 in 159 different sequences
Number of true positive hits 155 in 155 different sequences
Number of 'unknown' hits
Number of false positive hits 4 in 4 different sequences
Number of false negative sequences 35
Number of 'partial' sequences 2
Precision (true positives / (true positives + false positives)) 97.48 %
Recall (true positives / (true positives + false negatives)) 81.58 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
155 sequences

6DCS_SOYBN  (P26690), A1A1A_DANRE (Q6AZW2), A1A1B_DANRE (Q568L5), 
AK1A1_BOVIN (Q3ZCJ2), AK1A1_CHICK (Q5ZK84), AK1A1_CRIGR (O70473), 
AK1A1_HUMAN (P14550), AK1A1_MOUSE (Q9JII6), AK1A1_PIG   (P50578), 
AK1A1_PONAB (Q5R5D5), AK1A1_RAT   (P51635), AK1A1_XENLA (Q6GMC7), 
AK1A1_XENTR (Q28FD1), AK1BA_HUMAN (O60218), AK1BF_HUMAN (C9JRZ8), 
AK1C1_HUMAN (Q04828), AK1C1_MACFA (Q95JH7), AK1C1_MACFU (Q95JH6), 
AK1C1_PONAB (Q5REQ0), AK1C2_HUMAN (P52895), AK1C3_HUMAN (P42330), 
AK1C3_PONAB (Q5R7C9), AK1C4_HUMAN (P17516), AK1C4_MACFA (Q95JH5), 
AK1C4_MACFU (Q95JH4), AK1CD_MESAU (P82809), AK1CD_MOUSE (Q8VC28), 
AK1CL_MOUSE (Q91WR5), AK1CL_RAT   (Q6AYQ2), AK1CN_HORSE (Q1XAA8), 
AK1CO_HORSE (Q6W8P9), AK1D1_HUMAN (P51857), AK1D1_MOUSE (Q8VCX1), 
AK1D1_RABIT (Q9TV64), AK1D1_RAT   (P31210), AK2E4_BOMMO (H9JTG9), 
AKC1H_MOUSE (Q8K023), AKC1H_RAT   (P51652), AKCL2_HUMAN (Q96JD6), 
AKCL2_MACFA (Q4R802), AKCL2_MOUSE (Q9DCT1), AKCL2_PIG   (P82125), 
AKCL2_RAT   (Q5U1Y4), AKRC8_ARATH (O80944), AKRC9_ARATH (Q0PGJ6), 
AKRCA_ARATH (Q84TF0), AKRCB_ARATH (Q9M338), ALD1_MOUSE  (P21300), 
ALD1_RAT    (Q5RJP0), ALD2_CRIGR  (O08782), ALD2_MOUSE  (P45377), 
ALDR_BOVIN  (P16116), ALDR_ENCCU  (Q8SSK6), ALDR_HORVU  (P23901), 
ALDR_HUMAN  (P15121), ALDR_MOUSE  (P45376), ALDR_PIG    (P80276), 
ALDR_RABIT  (P15122), ALDR_RAT    (P07943), ALDX_SPOSA  (P27800), 
ALRA_DICDI  (Q6IMN8), ALRB_DICDI  (Q54NZ7), ALRC_DICDI  (Q55FL3), 
ARA1_YEAST  (P38115), COR11_PAPSO (Q9SQ70), COR12_PAPSO (Q9SQ69), 
COR13_PAPSO (Q9SQ68), COR14_PAPSO (Q9SQ67), COR15_PAPSO (B9VRJ2), 
COR2_PAPSO  (Q9SQ64), CPRC1_CANPA (Q76L37), CRO_LITCT   (P17264), 
CRO_RANTE   (P02532), DDBX_BOVIN  (P52898), DHB5_MOUSE  (P70694), 
DIDH_RAT    (P23457), DKGA_ECO57  (Q8XBT6), DKGA_ECOLI  (Q46857), 
DKGA_SALTI  (P58744), DKGA_SALTY  (Q8ZM06), DKGA_YERPE  (Q8ZI40), 
DKGB_CORSS  (P15339), DKGB_ECO57  (Q8X7Z7), DKGB_ECOLI  (P30863), 
DKGB_SALTI  (Q8Z988), DKGB_SALTY  (Q8ZRM7), DKGB_YERPE  (Q8ZH36), 
GALUR_FRAAN (O49133), GAR1_HYPJE  (Q3ZFI7), GCY1_YEAST  (P14065), 
GRE3_YEAST  (P38715), GR_BACSU    (O32210), KAR_YEAST   (Q07551), 
MER_ERYCB   (E7C196), NADO1_ORYSJ (Q7G764), NADO2_ORYSJ (Q7G765), 
PE2R_RABIT  (P80508), PGFS1_BOVIN (P05980), PGFS2_BOVIN (P52897), 
PGFS_LEIMA  (P22045), PGFS_TRYBB  (Q9GV41), PGFS_TRYCC  (Q4DJ07), 
PLR1_ARATH  (Q56Y42), S6PD_MALDO  (P28475), XYL1_ARTOC  (C5FFQ7), 
XYL1_ASPCL  (A1CRI1), XYL1_ASPFC  (B0XNR0), XYL1_ASPFN  (B8N195), 
XYL1_ASPFU  (Q4WJT9), XYL1_ASPNC  (A2Q8B5), XYL1_ASPNG  (Q9P8R5), 
XYL1_ASPOR  (Q2UKD0), XYL1_ASPTN  (Q0CUL0), XYL1_CANBO  (Q8X195), 
XYL1_CANPA  (Q6Y0Z3), XYL1_CANTE  (O74237), XYL1_CANTR  (O13283), 
XYL1_EMENI  (Q5BGA7), XYL1_HYPJE  (Q876L8), XYL1_KLULA  (P49378), 
XYL1_MAGO7  (G4N708), XYL1_NEOFI  (A1D4E3), XYL1_PICGU  (O94735), 
XYL1_PICST  (P31867), XYL1_SCHSH  (Q9P430), XYL2_CANTR  (P87039), 
Y1669_ARATH (Q94A68), Y1669_MYCLB (B8ZS00), Y1669_MYCLE (O69462), 
Y1744_MYCMM (B2HIJ9), Y1918_MYCSJ (A3PXS9), Y1919_MYCSJ (A3PXT0), 
Y1938_MYCSS (Q1BAN7), Y1984_MYCSK (A1UEC5), Y1985_MYCSK (A1UEC6), 
Y1987_MYCUA (A0PQ11), Y2161_MYCVP (A1T726), Y2407_MYCS2 (A0QV09), 
Y2408_MYCS2 (A0QV10), Y2971_MYCTO (P9WQA4), Y2971_MYCTU (P9WQA5), 
Y2993_MYCBP (A1KMW6), Y2996_MYCBO (Q7TXI6), Y2999_MYCTA (A5U6Y1), 
Y3007_MYCPA (Q73VK6), Y3816_MYCA1 (A0QJ99), Y4149_MYCPA (Q73SC5), 
Y4483_MYCA1 (A0QL30), YBN4_SCHPO  (O42888), YDG7_SCHPO  (Q10494), 
YJ66_YEAST  (P47137), YKW2_SCHPO  (Q9C1X5), YOF5_CAEEL  (Q09632), 
YPR1_YEAST  (Q12458), YTBE_BACSU  (O34678)
» More

UniProtKB/Swiss-Prot
False negative sequences
35 sequences

AKCL1_HUMAN (Q5T2L2), AKR1_ARATH  (Q9C5B9), AKR1_ORYSI  (B8ASB2), 
AKR1_ORYSJ  (Q0JE32), AKR1_SOYBN  (C6TBN2), AKR2_ORYSI  (A2XRZ0), 
AKR2_ORYSJ  (Q7XT99), AKR3_ORYSI  (A2XRZ6), AKR3_ORYSJ  (Q7XQ45), 
AKR6_ARATH  (F4HPY8), ALKR2_ARATH (Q84M96), ALKR3_ARATH (O22707), 
ALKR4_ARATH (Q93ZN2), ALKR5_ARATH (Q9ASZ9), ARA2_YEAST  (Q04212), 
DKGA_CORSC  (P06632), DTDH_MUCMU  (Q01213), FCDH_PSESP  (Q52472), 
GALDH_ARATH (O81884), GLD1_HYPJE  (Q0GYU5), GLD2_HYPJE  (Q0GYU4), 
I3ACR_SCHPO (O13848), MORA_PSEPU  (Q02198), MORA_RABIT  (P82810), 
PERR_RAUSE  (Q3L181), PLR1_SCHPO  (O14295), PLR1_YEAST  (Q06494), 
PLR2_SCHPO  (O94521), PRD1_MAGO7  (G4MZI3), XYL1_PACTA  (P78736), 
Y4205_MYCGI (A4TE41), YER5_SCHPO  (O14088), YEZB_SCHPO  (O14125), 
YH5B_SCHPO  (O94315), YRPG_BACSU  (O05408)
» More

UniProtKB/Swiss-Prot
'Partial' sequences
2 sequences

CROB_LEPLU  (P49261), DHGP_ASPNG  (P55804)

		
UniProtKB/Swiss-Prot
False positive sequences
4 sequences

CO6A1_XENLA (Q801S8), CUE3_YEAST  (P53137), GS69_BACSU  (P80874), 
IOLS_BACSU  (P46336)
» More

PDB
[Detailed view]
249 PDB

1ABN; 1ADS; 1AE4; 1AFS; 1AH0; 1AH3; 1AH4; 1AZ1; 1AZ2; 1C9W; 1CWN; 1DLA; 1EF3; 1EKO; 1EL3; 1FRB; 1HQT; 1IEI; 1IHI; 1J96; 1JEZ; 1K8C; 1LWI; 1MAR; 1MI3; 1MRQ; 1MZR; 1PWL; 1PWM; 1Q13; 1Q5M; 1R38; 1RAL; 1RY0; 1RY8; 1S1P; 1S1R; 1S2A; 1S2C; 1SM9; 1T40; 1T41; 1US0; 1VBJ; 1X96; 1X97; 1X98; 1XF0; 1XGD; 1XJB; 1YE4; 1YE6; 1Z3N; 1Z89; 1Z8A; 1Z9A; 1ZQ5; 1ZUA; 2ACQ; 2ACR; 2ACS; 2ACU; 2AGT; 2ALR; 2BGQ; 2BGS; 2DUX; 2DUZ; 2DV0; 2F2K; 2F38; 2FGB; 2FVL; 2FZ8; 2FZ9; 2FZB; 2FZD; 2HDJ; 2HE5; 2HE8; 2HEJ; 2HV5; 2HVN; 2HVO; 2I16; 2I17; 2IKG; 2IKH; 2IKI; 2IKJ; 2INE; 2INZ; 2IPF; 2IPG; 2IPJ; 2IPW; 2IQ0; 2IQD; 2IS7; 2ISF; 2J8T; 2NVC; 2NVD; 2P5N; 2PD5; 2PD9; 2PDB; 2PDC; 2PDF; 2PDG; 2PDH; 2PDI; 2PDJ; 2PDK; 2PDL; 2PDM; 2PDN; 2PDP; 2PDQ; 2PDU; 2PDW; 2PDX; 2PDY; 2PEV; 2PF8; 2PFH; 2PZN; 2QXW; 2R24; 2VDG; 2WZM; 2WZT; 3B3D; 3BCJ; 3BUR; 3BUV; 3BV7; 3C3U; 3CAQ; 3CAS; 3CAV; 3CMF; 3COT; 3CV6; 3CV7; 3D3F; 3DN5; 3DOP; 3F7J; 3FJN; 3FX4; 3G1R; 3G5E; 3GHR; 3GHS; 3GHT; 3GHU; 3GUG; 3H4G; 3H7R; 3H7U; 3LBO; 3LD5; 3LEN; 3LEP; 3LQG; 3LQL; 3LZ3; 3LZ5; 3M0I; 3M4H; 3M64; 3MB9; 3MC5; 3NTY; 3O3R; 3ONB; 3ONC; 3P2V; 3Q65; 3Q67; 3QKZ; 3R43; 3R58; 3R6I; 3R7M; 3R8G; 3R8H; 3R94; 3RX2; 3RX3; 3RX4; 3S3G; 3T42; 3U2C; 3UFY; 3UG8; 3UGR; 3UWE; 3UZW; 3UZX; 3UZY; 3UZZ; 3V35; 3V36; 3WCZ; 3WG6; 4DBS; 4DBU; 4DBW; 4DZ5; 4F40; 4FA3; 4FAL; 4FAM; 4FZI; 4G5D; 4GA8; 4GAB; 4GAC; 4GCA; 4GIE; 4GQ0; 4GQG; 4H7C; 4HMN; 4I5X; 4IGS; 4IJC; 4IJR; 4JIH; 4JII; 4JIR; 4JQ1; 4JQ2; 4JQ3; 4JQ4; 4JQA; 4JTQ; 4JTR; 4L1W; 4L1X; 4LAU; 4LAZ; 4LB3; 4LB4; 4LBR; 4LBS; 4OTK
» More

View entry in original PROSITE format
View entry in raw text format (no links)
Direct ScanProsite submission