To improve security and privacy, we are moving our web pages and services from HTTP to HTTPS.
To give users of web services time to transition to HTTPS, we will support separate HTTP and HTTPS services until the end of 2017.
From January 2018 most HTTP traffic will be automatically redirected to HTTPS. [more...]
View this page in https
Entry: PS00078

General information about the entry

Entry name [info] COX2
Accession [info] PS00078
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED; 01-NOV-1997 DATA UPDATE; 22-NOV-2017 INFO UPDATE.
PROSITE Doc. [info] PDOC00075

Name and characterization of the entry

Description [info] CO II and nitrous oxide reductase dinuclear copper centers signature.
Pattern [info]
V-x-H-x(33,40)-C-x(3)-C-x(3)-H-x(2)-M.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2017_11 which contains 556'196 sequence entries.


Total number of hits 325 in 325 different sequences
Number of true positive hits 325 in 325 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 15
Number of 'partial' sequences 9
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 95.59 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] copper at position 3
Site [info] copper at position 5
Site [info] copper at position 7
Site [info] copper at position 9
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
325 sequences

AOX2_AERPE  (Q9YDX7    ), COX1_ACACA  (Q37370    ), COX1_DICCI  (Q2LCQ6    ), 
COX1_DICDI  (O21042    ), COX2_ACHDO  (P29870    ), COX2_ACOIG  (Q38S50    ), 
COX2_ACOWI  (P50672    ), COX2_ADABI  (P29871    ), COX2_AEDAE  (P50692    ), 
COX2_AILFU  (Q3L6W7    ), COX2_AILME  (Q2Y0B9    ), COX2_ALBCA  (P48889    ), 
COX2_ALBTU  (Q09334    ), COX2_ALLMI  (O47870    ), COX2_ALOPA  (P98024    ), 
COX2_ANAPL  (P98019    ), COX2_ANIIM  (Q38S38    ), COX2_ANOGA  (P34840    ), 
COX2_ANOQU  (P33505    ), COX2_ANTAM  (Q37369    ), COX2_AOTNI  (Q7IC90    ), 
COX2_APIFL  (P50267    ), COX2_APIKO  (P50268    ), COX2_APILI  (P20375    ), 
COX2_APOMY  (Q38S35    ), COX2_APOSM  (Q38S29    ), COX2_APOSY  (P50673    ), 
COX2_APTAU  (O03889    ), COX2_ARATH  (P93285    ), COX2_ARTSF  (Q37706    ), 
COX2_ARVSO  (Q38S26    ), COX2_ASCSU  (P24882    ), COX2_ASHGO  (Q7YFV7    ), 
COX2_ATEMI  (Q7J6G4    ), COX2_BACP3  (Q03438    ), COX2_BACPE  (Q04441    ), 
COX2_BACSU  (P24011    ), COX2_BALBO  (Q599A0    ), COX2_BALMU  (P41294    ), 
COX2_BALPH  (P24986    ), COX2_BATGR  (Q38S23    ), COX2_BERBO  (Q38S20    ), 
COX2_BETVU  (P98012    ), COX2_BISBI  (Q37416    ), COX2_BISBO  (P68296    ), 
COX2_BOSGA  (P68295    ), COX2_BOSIN  (P68553    ), COX2_BOSJA  (P68294    ), 
COX2_BOSMU  (P68554    ), COX2_BOSTR  (Q37419    ), COX2_BOVIN  (P68530    ), 
COX2_BRAFL  (O47428    ), COX2_BRAHY  (Q9GCE7    ), COX2_BRALA  (O79417    ), 
COX2_BREAN  (P43369    ), COX2_BRECS  (P43370    ), COX2_BRENA  (P43372    ), 
COX2_BUBDE  (P50678    ), COX2_CAEBR  (Q8HEC3    ), COX2_CAEEL  (P24894    ), 
COX2_CAERE  (Q8SEM9    ), COX2_CAIMO  (P50666    ), COX2_CALGO  (P50661    ), 
COX2_CANAD  (O47667    ), COX2_CANAL  (Q9B8D8    ), COX2_CANAU  (O47669    ), 
COX2_CANGA  (P43373    ), COX2_CANLA  (P67781    ), COX2_CANLF  (P67780    ), 
COX2_CANLU  (P67782    ), COX2_CANME  (O47671    ), COX2_CANSI  (P98031    ), 
COX2_CAPHI  (Q37430    ), COX2_CARAU  (O78682    ), COX2_CASBE  (O03890    ), 
COX2_CAVAP  (P50683    ), COX2_CEPBA  (P98043    ), COX2_CERGA  (P98020    ), 
COX2_CERSI  (O03851    ), COX2_CERTH  (O47672    ), COX2_CHEME  (P98027    ), 
COX2_CHICK  (P18944    ), COX2_CHLAE  (P26455    ), COX2_CHOBI  (P98025    ), 
COX2_CHOCR  (P48869    ), COX2_CHOFU  (P84288    ), COX2_CHOOC  (P84289    ), 
COX2_CHOPI  (P84290    ), COX2_CHORO  (P98030    ), COX2_CHRBR  (O47670    ), 
COX2_CONPN  (Q38S17    ), COX2_CORDI  (Q6NG98    ), COX2_COREF  (Q8FNQ7    ), 
COX2_CORGL  (Q8NNK2    ), COX2_COTJA  (P50684    ), COX2_CRABU  (P50685    ), 
COX2_CRACA  (P50662    ), COX2_CTEFE  (P29872    ), COX2_CULQU  (P50693    ), 
COX2_CUOAL  (O47668    ), COX2_CYACA  (P48870    ), COX2_CYBMR  (P47918    ), 
COX2_CYBSA  (P06029    ), COX2_CYPCA  (P24987    ), COX2_DACMI  (Q38S14    ), 
COX2_DAMPP  (P50679    ), COX2_DANRE  (Q9MIY7    ), COX2_DASNO  (P50687    ), 
COX2_DAUMA  (P98032    ), COX2_DEBHA  (A9RAG1    ), COX2_DEKBR  (P43374    ), 
COX2_DESAU  (Q38S65    ), COX2_DIDVI  (P41311    ), COX2_DROAI  (Q85TA0    ), 
COX2_DROAL  (P84201    ), COX2_DROAM  (P29856    ), COX2_DROAT  (P84202    ), 
COX2_DROAZ  (P84287    ), COX2_DROBF  (P29859    ), COX2_DROLO  (P29860    ), 
COX2_DROME  (P00408    ), COX2_DROMI  (P67797    ), COX2_DRONO  (O03891    ), 
COX2_DRONR  (P67795    ), COX2_DROPE  (P67798    ), COX2_DROPS  (P67799    ), 
COX2_DROSI  (P50253    ), COX2_DROSU  (P29865    ), COX2_DROTO  (P67796    ), 
COX2_DROYA  (P00409    ), COX2_DUGDU  (Q8W9N3    ), COX2_EENNA  (P43375    ), 
COX2_ELEMA  (Q2I3H1    ), COX2_EMEND  (P13588    ), COX2_EQUAS  (P92478    ), 
COX2_EULMA  (P98033    ), COX2_EXERO  (P29873    ), COX2_FELCA  (P48890    ), 
COX2_FORLA  (P34189    ), COX2_GADMO  (Q37741    ), COX2_GALME  (P29874    ), 
COX2_GALSE  (P50688    ), COX2_GALVR  (P50686    ), COX2_GAZSP  (P50680    ), 
COX2_GEOCP  (P50689    ), COX2_GERGE  (Q38S62    ), COX2_GERRO  (Q38S56    ), 
COX2_GERVA  (Q37476    ), COX2_GORBE  (Q37472    ), COX2_GORGO  (P26456    ), 
COX2_HALGR  (P38596    ), COX2_HAPGR  (P98034    ), COX2_HIPAM  (Q9ZZY8    ), 
COX2_HORSE  (P48660    ), COX2_HUMAN  (P00403    ), COX2_HYBUN  (Q38S11    ), 
COX2_HYLLA  (Q96127    ), COX2_HYLPR  (Q38S08    ), COX2_KLULA  (P20387    ), 
COX2_LACK1  (Q9XLW8    ), COX2_LACTC  (P43376    ), COX2_LAGLA  (P98036    ), 
COX2_LASSP  (P29875    ), COX2_LATCH  (O03848    ), COX2_LEGFO  (Q38S05    ), 
COX2_LEITA  (P14545    ), COX2_LEMBA  (Q38S02    ), COX2_LEMCA  (P98035    ), 
COX2_LEOSA  (Q38S00    ), COX2_LOCMI  (P14573    ), COX2_LOPFL  (Q38S47    ), 
COX2_LOXAF  (Q9TA26    ), COX2_LUMTE  (Q37545    ), COX2_LYCCU  (O47676    ), 
COX2_LYCGR  (O48267    ), COX2_LYCPI  (O47674    ), COX2_LYCSE  (O47678    ), 
COX2_LYCSM  (O79549    ), COX2_LYCVE  (Q7J6G2    ), COX2_MACCA  (Q37548    ), 
COX2_MACFA  (P11948    ), COX2_MACMU  (P98038    ), COX2_MACRO  (P92662    ), 
COX2_MAIZE  (P00412    ), COX2_MALLO  (Q38RZ7    ), COX2_MALTY  (Q37547    ), 
COX2_MAMPR  (Q38PR9    ), COX2_MANLE  (P98037    ), COX2_MARPO  (P26857    ), 
COX2_MAXBA  (Q38RZ2    ), COX2_MAXSU  (Q38RY9    ), COX2_MERSH  (Q38S59    ), 
COX2_METSE  (O47496    ), COX2_MICNA  (Q38S41    ), COX2_MICPE  (P24988    ), 
COX2_MICTV  (Q7IKU8    ), COX2_MOUSE  (P00405    ), COX2_MYCBO  (P63855    ), 
COX2_MYCLE  (Q9CCF1    ), COX2_MYCPA  (Q73YL5    ), COX2_MYCTO  (P9WP68    ), 
COX2_MYCTU  (P9WP69    ), COX2_MYTED  (Q00227    ), COX2_MYXGL  (Q9G2X2    ), 
COX2_NEUCR  (P00411    ), COX2_NIVCU  (Q38RY6    ), COX2_NOCFA  (Q5YZ37    ), 
COX2_NOTPE  (O03892    ), COX2_NYCCO  (P98039    ), COX2_NYCPR  (O47675    ), 
COX2_OENBE  (P05490    ), COX2_OENHY  (Q38RY0    ), COX2_ONCFA  (P29876    ), 
COX2_ONCMY  (P48171    ), COX2_ORNAN  (Q37718    ), COX2_PANPA  (P26457    ), 
COX2_PANTR  (P50690    ), COX2_PAPAN  (P68297    ), COX2_PAPHA  (P68298    ), 
COX2_PARDE  (P08306    ), COX2_PARLI  (P12701    ), COX2_PARTE  (P08749    ), 
COX2_PATPE  (Q37411    ), COX2_PELSU  (O79673    ), COX2_PERAM  (P29877    ), 
COX2_PERFA  (Q37595    ), COX2_PETMA  (Q37604    ), COX2_PHOVI  (Q00528    ), 
COX2_PHYHA  (Q37596    ), COX2_PHYME  (Q02212    ), COX2_PIG    (P50667    ), 
COX2_PISOC  (P25002    ), COX2_PNECA  (P29163    ), COX2_PODAN  (P20682    ), 
COX2_POLOR  (Q96183    ), COX2_PONAB  (P92693    ), COX2_PONPY  (Q37605    ), 
COX2_PRAJA  (Q38RX1    ), COX2_PRATA  (Q38RW8    ), COX2_PRATU  (Q38RW5    ), 
COX2_PROTA  (P98042    ), COX2_RABIT  (P98049    ), COX2_RAT    (P00406    ), 
COX2_RHAPU  (Q38RV6    ), COX2_RHEAM  (O03893    ), COX2_RHIDA  (Q37643    ), 
COX2_RHISA  (O99819    ), COX2_RHIUN  (Q96190    ), COX2_RHOSH  (Q03736    ), 
COX2_RHYIS  (Q38RV3    ), COX2_RICBR  (Q1RI44    ), COX2_RICCN  (Q92I65    ), 
COX2_RICFE  (Q4ULU3    ), COX2_RICPR  (Q9ZDC6    ), COX2_ROULE  (Q37649    ), 
COX2_RUSUN  (Q37440    ), COX2_SACEX  (P43377    ), COX2_SALSA  (Q37677    ), 
COX2_SCHGR  (P29878    ), COX2_SCHPO  (P21534    ), COX2_SCICA  (P50691    ), 
COX2_SCYCA  (O79404    ), COX2_SIMVI  (P98021    ), COX2_SITGR  (P29879    ), 
COX2_SPEVE  (O47679    ), COX2_SQUAC  (Q9ZZ51    ), COX2_STRAW  (Q82AL0    ), 
COX2_STRCA  (O21400    ), COX2_STRCO  (Q9X814    ), COX2_STRPU  (P15545    ), 
COX2_SUNME  (Q38RU7    ), COX2_SYMST  (P29880    ), COX2_SYMSY  (P25312    ), 
COX2_SYNCA  (P50675    ), COX2_SYNY3  (Q06474    ), COX2_TACSP  (Q37691    ), 
COX2_TAMAM  (Q7IZ21    ), COX2_TAMBU  (Q7IZ16    ), COX2_TAMCA  (Q7IZ15    ), 
COX2_TAMCI  (Q7IZ14    ), COX2_TAMDO  (Q7IZ11    ), COX2_TAMMR  (Q7IZ08    ), 
COX2_TAMPL  (Q7IZ01    ), COX2_TAMQA  (Q9G5S9    ), COX2_TAMRF  (Q9G1N5    ), 
COX2_TAMSO  (Q9G0U1    ), COX2_TAMTO  (Q9G185    ), COX2_TARSY  (P98046    ), 
COX2_TATEM  (Q38S53    ), COX2_TETNG  (Q4JQI4    ), COX2_THEGE  (P98044    ), 
COX2_THET8  (Q5SJ80    ), COX2_THETH  (P98052    ), COX2_THEVL  (P98054    ), 
COX2_TINMA  (O03895    ), COX2_TRAIM  (Q37685    ), COX2_TRIRU  (Q01556    ), 
COX2_TRYBB  (P04372    ), COX2_TRYCR  (P98023    ), COX2_TUPGL  (Q37684    ), 
COX2_UROCA  (Q38RU4    ), COX2_UROCI  (O48276    ), COX2_USTMA  (Q0H8Y7    ), 
COX2_VANPO  (A6H4Q5    ), COX2_VARVI  (P98047    ), COX2_VIGUN  (P32646    ), 
COX2_VULCO  (Q539C6    ), COX2_VULMA  (O47680    ), COX2_VULVU  (O47681    ), 
COX2_VULZE  (O47673    ), COX2_WHEAT  (P00413    ), COX2_WICCA  (P48871    ), 
COX2_XENLA  (P00407    ), COX2_YARLI  (Q9B6D5    ), COX2_YEAST  (P00410    ), 
COX2_YPOMA  (P98048    ), COX2_ZANCU  (Q3T4C0    ), COX2_ZELHI  (Q38RU1    ), 
COX2_ZOOAN  (P29881    ), COXM_BRADU  (P98053    ), COXT_SOYBN  (Q02226    ), 
NOSZ_PSEAE  (Q9HYL2    ), NOSZ_PSEAI  (Q01710    ), NOSZ_PSEFL  (Q9F0W4    ), 
NOSZ_PSEST  (P19573    )
» more

UniProtKB/Swiss-Prot
False negative sequences
15 sequences

COX2_DAUCA  (P27168    ), COX2_LYCGY  (O47677    ), COX2_ORYSJ  (P04373    ), 
COX2_PARPR  (P08748    ), COX2_PEA    (P08744    ), COX2_SHEEP  (O78750    ), 
COX2_SOYBN  (P05491    ), NOSZ_ACHCY  (P94127    ), NOSZ_BRADU  (Q89XJ6    ), 
NOSZ_BRUME  (Q8YBC6    ), NOSZ_BRUSU  (Q8FX16    ), NOSZ_CUPNH  (Q59105    ), 
NOSZ_PARDE  (Q51705    ), NOSZ_RALSO  (Q8XQB8    ), NOSZ_RHIME  (Q59746    )
» more

UniProtKB/Swiss-Prot
'Partial' sequences
9 sequences

COX2_AMICA  (P29655    ), COX2_ATRSP  (P29656    ), COX2_GEOSD  (P29657    ), 
COX2_GOMVA  (P29658    ), COX2_LEPOC  (P29659    ), COX2_MEGAT  (P29660    ), 
COX2_POLSX  (P29661    ), COX2_SCAPL  (P29662    ), COX2_SOLTU  (P80498    )
» more

PDB
[Detailed view]
81 PDB

1AR1; 1EHK; 1M56; 1M57; 1OCC; 1OCO; 1OCR; 1OCZ; 1QLE; 1V54; 1V55; 1XME; 2CUA; 2DYR; 2DYS; 2EIJ; 2EIK; 2EIL; 2EIM; 2EIN; 2FWL; 2GSM; 2LLN; 2OCC; 2QPD; 2QPE; 2Y69; 2YBB; 2ZXW; 3ABK; 3ABL; 3ABM; 3AG1; 3AG2; 3AG3; 3AG4; 3ASN; 3ASO; 3BVD; 3DTU; 3EH3; 3EH4; 3EH5; 3EHB; 3FYE; 3FYI; 3HB3; 3QJQ; 3QJR; 3QJS; 3QJT; 3QJU; 3QJV; 3S33; 3S38; 3S39; 3S3A; 3S3B; 3S3C; 3S3D; 3S8F; 3S8G; 3SBP; 3SBQ; 3SBR; 3WG7; 3X2Q; 4FA7; 4FAA; 4G70; 4G71; 4G72; 4G7Q; 4G7R; 4G7S; 4GP4; 4GP5; 4GP8; 4N4Y; 5B1A; 5B1B
» more

View entry in original PROSITE format
View entry in raw text format (no links)
Direct ScanProsite submission