Due to maintenance work, this service will not be available on Monday December 12th between 07.00 am and 9.00 am CEST.
Entry: PS00078

General information about the entry

Entry name [info] COX2
Accession [info] PS00078
Entry type [info] PATTERN
Date [info] APR-1990 (CREATED); NOV-1997 (DATA UPDATE); OCT-2016 (INFO UPDATE).
PROSITE Doc. [info] PDOC00075

Name and characterization of the entry

Description [info] CO II and nitrous oxide reductase dinuclear copper centers signature.
Pattern [info]
V-x-H-x(33,40)-C-x(3)-C-x(3)-H-x(2)-M.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2016_11 which contains 553'231 sequence entries.


Total number of hits 325 in 325 different sequences
Number of true positive hits 325 in 325 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 15
Number of 'partial' sequences 9
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 95.59 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] copper at position 3
Site [info] copper at position 5
Site [info] copper at position 7
Site [info] copper at position 9
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
325 sequences

AOX2_AERPE  (Q9YDX7    ), COX1_ACACA  (Q37370    ), COX1_DICCI  (Q2LCQ6    ), 
COX1_DICDI  (O21042    ), COX2_ACHDO  (P29870    ), COX2_ACOIG  (Q38S50    ), 
COX2_ACOWI  (P50672    ), COX2_ADABI  (P29871    ), COX2_AEDAE  (P50692    ), 
COX2_AILFU  (Q3L6W7    ), COX2_AILME  (Q2Y0B9    ), COX2_ALBCA  (P48889    ), 
COX2_ALBTU  (Q09334    ), COX2_ALLMI  (O47870    ), COX2_ALOPA  (P98024    ), 
COX2_ANAPL  (P98019    ), COX2_ANIIM  (Q38S38    ), COX2_ANOGA  (P34840    ), 
COX2_ANOQU  (P33505    ), COX2_ANTAM  (Q37369    ), COX2_AOTNI  (Q7IC90    ), 
COX2_APIFL  (P50267    ), COX2_APIKO  (P50268    ), COX2_APILI  (P20375    ), 
COX2_APOMY  (Q38S35    ), COX2_APOSM  (Q38S29    ), COX2_APOSY  (P50673    ), 
COX2_APTAU  (O03889    ), COX2_ARATH  (P93285    ), COX2_ARTSF  (Q37706    ), 
COX2_ARVSO  (Q38S26    ), COX2_ASCSU  (P24882    ), COX2_ASHGO  (Q7YFV7    ), 
COX2_ATEMI  (Q7J6G4    ), COX2_BACP3  (Q03438    ), COX2_BACPE  (Q04441    ), 
COX2_BACSU  (P24011    ), COX2_BALBO  (Q599A0    ), COX2_BALMU  (P41294    ), 
COX2_BALPH  (P24986    ), COX2_BATGR  (Q38S23    ), COX2_BERBO  (Q38S20    ), 
COX2_BETVU  (P98012    ), COX2_BISBI  (Q37416    ), COX2_BISBO  (P68296    ), 
COX2_BOSGA  (P68295    ), COX2_BOSIN  (P68553    ), COX2_BOSJA  (P68294    ), 
COX2_BOSMU  (P68554    ), COX2_BOSTR  (Q37419    ), COX2_BOVIN  (P68530    ), 
COX2_BRAFL  (O47428    ), COX2_BRAHY  (Q9GCE7    ), COX2_BRALA  (O79417    ), 
COX2_BREAN  (P43369    ), COX2_BRECS  (P43370    ), COX2_BRENA  (P43372    ), 
COX2_BUBDE  (P50678    ), COX2_CAEBR  (Q8HEC3    ), COX2_CAEEL  (P24894    ), 
COX2_CAERE  (Q8SEM9    ), COX2_CAIMO  (P50666    ), COX2_CALGO  (P50661    ), 
COX2_CANAD  (O47667    ), COX2_CANAL  (Q9B8D8    ), COX2_CANAU  (O47669    ), 
COX2_CANGA  (P43373    ), COX2_CANLA  (P67781    ), COX2_CANLF  (P67780    ), 
COX2_CANLU  (P67782    ), COX2_CANME  (O47671    ), COX2_CANSI  (P98031    ), 
COX2_CAPHI  (Q37430    ), COX2_CARAU  (O78682    ), COX2_CASBE  (O03890    ), 
COX2_CAVAP  (P50683    ), COX2_CERGA  (P98020    ), COX2_CERSI  (O03851    ), 
COX2_CERTH  (O47672    ), COX2_CHEME  (P98027    ), COX2_CHICK  (P18944    ), 
COX2_CHLAE  (P26455    ), COX2_CHOBI  (P98025    ), COX2_CHOCR  (P48869    ), 
COX2_CHOFU  (P84288    ), COX2_CHOOC  (P84289    ), COX2_CHOPI  (P84290    ), 
COX2_CHORO  (P98030    ), COX2_CHRBR  (O47670    ), COX2_CONPN  (Q38S17    ), 
COX2_CORDI  (Q6NG98    ), COX2_COREF  (Q8FNQ7    ), COX2_CORGL  (Q8NNK2    ), 
COX2_COTJA  (P50684    ), COX2_CRABU  (P50685    ), COX2_CRACA  (P50662    ), 
COX2_CTEFE  (P29872    ), COX2_CULQU  (P50693    ), COX2_CUOAL  (O47668    ), 
COX2_CYACA  (P48870    ), COX2_CYBMR  (P47918    ), COX2_CYBSA  (P06029    ), 
COX2_CYPCA  (P24987    ), COX2_DACMI  (Q38S14    ), COX2_DAMPP  (P50679    ), 
COX2_DANRE  (Q9MIY7    ), COX2_DASNO  (P50687    ), COX2_DAUMA  (P98032    ), 
COX2_DEBHA  (A9RAG1    ), COX2_DEKBR  (P43374    ), COX2_DESAU  (Q38S65    ), 
COX2_DIDVI  (P41311    ), COX2_DROAI  (Q85TA0    ), COX2_DROAL  (P84201    ), 
COX2_DROAM  (P29856    ), COX2_DROAT  (P84202    ), COX2_DROAZ  (P84287    ), 
COX2_DROBF  (P29859    ), COX2_DROLO  (P29860    ), COX2_DROME  (P00408    ), 
COX2_DROMI  (P67797    ), COX2_DRONO  (O03891    ), COX2_DRONR  (P67795    ), 
COX2_DROPE  (P67798    ), COX2_DROPS  (P67799    ), COX2_DROSI  (P50253    ), 
COX2_DROSU  (P29865    ), COX2_DROTO  (P67796    ), COX2_DROYA  (P00409    ), 
COX2_DUGDU  (Q8W9N3    ), COX2_EENNA  (P43375    ), COX2_ELEMA  (Q2I3H1    ), 
COX2_EMEND  (P13588    ), COX2_EQUAS  (P92478    ), COX2_EULMA  (P98033    ), 
COX2_EXERO  (P29873    ), COX2_FELCA  (P48890    ), COX2_FORLA  (P34189    ), 
COX2_GADMO  (Q37741    ), COX2_GALME  (P29874    ), COX2_GALSE  (P50688    ), 
COX2_GALVR  (P50686    ), COX2_GAZSP  (P50680    ), COX2_GEOCP  (P50689    ), 
COX2_GERGE  (Q38S62    ), COX2_GERRO  (Q38S56    ), COX2_GERVA  (Q37476    ), 
COX2_GORBE  (Q37472    ), COX2_GORGO  (P26456    ), COX2_HALGR  (P38596    ), 
COX2_HAPGR  (P98034    ), COX2_HIPAM  (Q9ZZY8    ), COX2_HORSE  (P48660    ), 
COX2_HUMAN  (P00403    ), COX2_HYBUN  (Q38S11    ), COX2_HYLLA  (Q96127    ), 
COX2_HYLPR  (Q38S08    ), COX2_KLULA  (P20387    ), COX2_LACK1  (Q9XLW8    ), 
COX2_LACTC  (P43376    ), COX2_LAGLA  (P98036    ), COX2_LASSP  (P29875    ), 
COX2_LATCH  (O03848    ), COX2_LEGFO  (Q38S05    ), COX2_LEITA  (P14545    ), 
COX2_LEMBA  (Q38S02    ), COX2_LEMCA  (P98035    ), COX2_LEOSA  (Q38S00    ), 
COX2_LOCMI  (P14573    ), COX2_LOPFL  (Q38S47    ), COX2_LOXAF  (Q9TA26    ), 
COX2_LUMTE  (Q37545    ), COX2_LYCCU  (O47676    ), COX2_LYCGR  (O48267    ), 
COX2_LYCPI  (O47674    ), COX2_LYCSE  (O47678    ), COX2_LYCSM  (O79549    ), 
COX2_LYCVE  (Q7J6G2    ), COX2_MACCA  (Q37548    ), COX2_MACFA  (P11948    ), 
COX2_MACMU  (P98038    ), COX2_MACRO  (P92662    ), COX2_MAIZE  (P00412    ), 
COX2_MALLO  (Q38RZ7    ), COX2_MALTY  (Q37547    ), COX2_MAMPR  (Q38PR9    ), 
COX2_MANLE  (P98037    ), COX2_MARPO  (P26857    ), COX2_MAXBA  (Q38RZ2    ), 
COX2_MAXSU  (Q38RY9    ), COX2_MERSH  (Q38S59    ), COX2_METSE  (O47496    ), 
COX2_MICNA  (Q38S41    ), COX2_MICPE  (P24988    ), COX2_MICTV  (Q7IKU8    ), 
COX2_MOUSE  (P00405    ), COX2_MYCBO  (P63855    ), COX2_MYCLE  (Q9CCF1    ), 
COX2_MYCPA  (Q73YL5    ), COX2_MYCTO  (P9WP68    ), COX2_MYCTU  (P9WP69    ), 
COX2_MYTED  (Q00227    ), COX2_MYXGL  (Q9G2X2    ), COX2_NEUCR  (P00411    ), 
COX2_NIVCU  (Q38RY6    ), COX2_NOCFA  (Q5YZ37    ), COX2_NOTPE  (O03892    ), 
COX2_NYCCO  (P98039    ), COX2_NYCPR  (O47675    ), COX2_OENBE  (P05490    ), 
COX2_OENHY  (Q38RY0    ), COX2_ONCFA  (P29876    ), COX2_ONCMY  (P48171    ), 
COX2_ORNAN  (Q37718    ), COX2_PANPA  (P26457    ), COX2_PANTR  (P50690    ), 
COX2_PAPAN  (P68297    ), COX2_PAPHA  (P68298    ), COX2_PARDE  (P08306    ), 
COX2_PARLI  (P12701    ), COX2_PARTE  (P08749    ), COX2_PATPE  (Q37411    ), 
COX2_PELSU  (O79673    ), COX2_PERAM  (P29877    ), COX2_PERFA  (Q37595    ), 
COX2_PETMA  (Q37604    ), COX2_PHOVI  (Q00528    ), COX2_PHYHA  (Q37596    ), 
COX2_PHYME  (Q02212    ), COX2_PIG    (P50667    ), COX2_PISOC  (P25002    ), 
COX2_PNECA  (P29163    ), COX2_PODAN  (P20682    ), COX2_POLOR  (Q96183    ), 
COX2_PONAB  (P92693    ), COX2_PONPY  (Q37605    ), COX2_PRAJA  (Q38RX1    ), 
COX2_PRATA  (Q38RW8    ), COX2_PRATU  (Q38RW5    ), COX2_PROTA  (P98042    ), 
COX2_RABIT  (P98049    ), COX2_RAT    (P00406    ), COX2_RHAPU  (Q38RV6    ), 
COX2_RHEAM  (O03893    ), COX2_RHIDA  (Q37643    ), COX2_RHISA  (O99819    ), 
COX2_RHIUN  (Q96190    ), COX2_RHOSH  (Q03736    ), COX2_RHYIS  (Q38RV3    ), 
COX2_RICBR  (Q1RI44    ), COX2_RICCN  (Q92I65    ), COX2_RICFE  (Q4ULU3    ), 
COX2_RICPR  (Q9ZDC6    ), COX2_ROULE  (Q37649    ), COX2_RUSUN  (Q37440    ), 
COX2_SACEX  (P43377    ), COX2_SALSA  (Q37677    ), COX2_SCHGR  (P29878    ), 
COX2_SCHPO  (P21534    ), COX2_SCICA  (P50691    ), COX2_SCYCA  (O79404    ), 
COX2_SIMVI  (P98021    ), COX2_SITGR  (P29879    ), COX2_SPEVE  (O47679    ), 
COX2_SQUAC  (Q9ZZ51    ), COX2_STRAW  (Q82AL0    ), COX2_STRCA  (O21400    ), 
COX2_STRCO  (Q9X814    ), COX2_STRPU  (P15545    ), COX2_SUNME  (Q38RU7    ), 
COX2_SYMST  (P29880    ), COX2_SYMSY  (P25312    ), COX2_SYNCA  (P50675    ), 
COX2_SYNY3  (Q06474    ), COX2_TACSP  (Q37691    ), COX2_TAMAM  (Q7IZ21    ), 
COX2_TAMBU  (Q7IZ16    ), COX2_TAMCA  (Q7IZ15    ), COX2_TAMCI  (Q7IZ14    ), 
COX2_TAMDO  (Q7IZ11    ), COX2_TAMMR  (Q7IZ08    ), COX2_TAMPL  (Q7IZ01    ), 
COX2_TAMQA  (Q9G5S9    ), COX2_TAMRF  (Q9G1N5    ), COX2_TAMSO  (Q9G0U1    ), 
COX2_TAMTO  (Q9G185    ), COX2_TARBA  (P98043    ), COX2_TARSY  (P98046    ), 
COX2_TATEM  (Q38S53    ), COX2_TETNG  (Q4JQI4    ), COX2_THEGE  (P98044    ), 
COX2_THET8  (Q5SJ80    ), COX2_THETH  (P98052    ), COX2_THEVL  (P98054    ), 
COX2_TINMA  (O03895    ), COX2_TRAIM  (Q37685    ), COX2_TRIRU  (Q01556    ), 
COX2_TRYBB  (P04372    ), COX2_TRYCR  (P98023    ), COX2_TUPGL  (Q37684    ), 
COX2_UROCA  (Q38RU4    ), COX2_UROCI  (O48276    ), COX2_USTMA  (Q0H8Y7    ), 
COX2_VANPO  (A6H4Q5    ), COX2_VARVI  (P98047    ), COX2_VIGUN  (P32646    ), 
COX2_VULCO  (Q539C6    ), COX2_VULMA  (O47680    ), COX2_VULVU  (O47681    ), 
COX2_VULZE  (O47673    ), COX2_WHEAT  (P00413    ), COX2_WICCA  (P48871    ), 
COX2_XENLA  (P00407    ), COX2_YARLI  (Q9B6D5    ), COX2_YEAST  (P00410    ), 
COX2_YPOMA  (P98048    ), COX2_ZANCU  (Q3T4C0    ), COX2_ZELHI  (Q38RU1    ), 
COX2_ZOOAN  (P29881    ), COXM_BRADU  (P98053    ), COXT_SOYBN  (Q02226    ), 
NOSZ_PSEAE  (Q9HYL2    ), NOSZ_PSEAI  (Q01710    ), NOSZ_PSEFL  (Q9F0W4    ), 
NOSZ_PSEST  (P19573    )
» more

UniProtKB/Swiss-Prot
False negative sequences
15 sequences

COX2_DAUCA  (P27168    ), COX2_LYCGY  (O47677    ), COX2_ORYSJ  (P04373    ), 
COX2_PARPR  (P08748    ), COX2_PEA    (P08744    ), COX2_SHEEP  (O78750    ), 
COX2_SOYBN  (P05491    ), NOSZ_ACHCY  (P94127    ), NOSZ_BRADU  (Q89XJ6    ), 
NOSZ_BRUME  (Q8YBC6    ), NOSZ_BRUSU  (Q8FX16    ), NOSZ_CUPNH  (Q59105    ), 
NOSZ_PARDE  (Q51705    ), NOSZ_RALSO  (Q8XQB8    ), NOSZ_RHIME  (Q59746    )
» more

UniProtKB/Swiss-Prot
'Partial' sequences
9 sequences

COX2_AMICA  (P29655    ), COX2_ATRSP  (P29656    ), COX2_GEOSD  (P29657    ), 
COX2_GOMVA  (P29658    ), COX2_LEPOC  (P29659    ), COX2_MEGAT  (P29660    ), 
COX2_POLSX  (P29661    ), COX2_SCAPL  (P29662    ), COX2_SOLTU  (P80498    )
» more

PDB
[Detailed view]
81 PDB

1AR1; 1EHK; 1M56; 1M57; 1OCC; 1OCO; 1OCR; 1OCZ; 1QLE; 1V54; 1V55; 1XME; 2CUA; 2DYR; 2DYS; 2EIJ; 2EIK; 2EIL; 2EIM; 2EIN; 2FWL; 2GSM; 2LLN; 2OCC; 2QPD; 2QPE; 2Y69; 2YBB; 2ZXW; 3ABK; 3ABL; 3ABM; 3AG1; 3AG2; 3AG3; 3AG4; 3ASN; 3ASO; 3BVD; 3DTU; 3EH3; 3EH4; 3EH5; 3EHB; 3FYE; 3FYI; 3HB3; 3QJQ; 3QJR; 3QJS; 3QJT; 3QJU; 3QJV; 3S33; 3S38; 3S39; 3S3A; 3S3B; 3S3C; 3S3D; 3S8F; 3S8G; 3SBP; 3SBQ; 3SBR; 3WG7; 3X2Q; 4FA7; 4FAA; 4G70; 4G71; 4G72; 4G7Q; 4G7R; 4G7S; 4GP4; 4GP5; 4GP8; 4N4Y; 5B1A; 5B1B
» more

View entry in original PROSITE format
View entry in raw text format (no links)
Direct ScanProsite submission