Entry: PS00080

General information about the entry

Entry name [info] MULTICOPPER_OXIDASE2
Accession [info] PS00080
Entry type [info] PATTERN
Date [info] APR-1990 (CREATED); OCT-1993 (DATA UPDATE); JUN-2015 (INFO UPDATE).
PROSITE Doc. [info] PDOC00076

Name and characterization of the entry

Description [info] Multicopper oxidases signature 2.
Pattern [info]
H-C-H-x(3)-H-x(3)-[AG]-[LM].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2015_08 which contains 320'201 sequence entries.


Total number of hits 93 in 93 different sequences
Number of true positive hits 90 in 90 different sequences
Number of 'unknown' hits 0
Number of false positive hits 3 in 3 different sequences
Number of false negative sequences 19
Number of 'partial' sequences 5
Precision (true positives / (true positives + false positives)) 96.77 %
Recall (true positives / (true positives + false negatives)) 82.57 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] copper_3 at position 1
Site [info] copper_1 at position 2
Site [info] copper_3 at position 3
Site [info] copper_1 at position 5
Site [info] copper_1 at position 8
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
90 sequences

ASO_CUCMA   (P24792), ASO_CUCPM   (P37064), ASO_CUCSA   (P14133), 
ASO_TOBAC   (Q40588), CERU_HUMAN  (P00450), CERU_MOUSE  (Q61147), 
CERU_RAT    (P13635), CERU_SHEEP  (Q9XT27), COPA_PSESM  (P59571), 
COPA_PSEUB  (P12374), CUEO_ECO57  (Q8X947), CUEO_ECOLI  (P36649), 
CUEO_SALTI  (Q8Z9E1), CUEO_SALTY  (Q8ZRS2), CUEO_YERPE  (Q8ZBK0), 
FET3_CANAX  (P78591), FET3_CANGA  (Q96WT3), FET3_KLULA  (Q6CII3), 
FET3_YEAST  (P38993), FET5_YEAST  (P43561), FIO1_SCHPO  (Q09920), 
GMC1_YEAST  (Q04399), HEPHL_ACRMI (B3EWZ9), HEPH_HUMAN  (Q9BQS7), 
HEPH_MOUSE  (Q9Z0Z4), HEPH_RAT    (Q920H8), HPHL1_HUMAN (Q6MZM0), 
HPHL1_MOUSE (Q3V1H3), LAC10_ARATH (Q6ID18), LAC10_ORYSJ (Q10ND7), 
LAC11_ARATH (Q8VZA1), LAC11_ORYSJ (Q0DHL5), LAC12_ARATH (Q9FLB5), 
LAC12_ORYSJ (Q0DHL2), LAC13_ARATH (Q9LYQ2), LAC14_ARATH (Q9FY79), 
LAC14_ORYSJ (Q69L99), LAC15_ARATH (Q84J37), LAC15_ORYSJ (Q339K6), 
LAC16_ARATH (Q1PDH6), LAC16_ORYSJ (Q7XE50), LAC17_ARATH (Q9FJD5), 
LAC17_ORYSJ (Q2RBK2), LAC18_ORYSI (A2XCN6), LAC18_ORYSJ (Q53LU4), 
LAC19_ORYSI (A2Y9C5), LAC19_ORYSJ (Q2R0L2), LAC1_AGABI  (Q12541), 
LAC1_ARATH  (Q9LMS3), LAC1_BOTFU  (Q12570), LAC1_CRYPA  (Q03966), 
LAC1_EMENI  (P17489), LAC1_MELAO  (Q70KY3), LAC1_NEUCR  (P06811), 
LAC1_ORYSJ  (Q5ZCW1), LAC1_PLEOS  (Q12729), LAC20_ORYSI (A2Y9C2), 
LAC20_ORYSJ (Q2R0L0), LAC21_ORYSJ (Q2QZ80), LAC22_ORYSJ (Q0IQU1), 
LAC23_ORYSJ (Q2QYS3), LAC24_ORYSJ (Q2QUN2), LAC25_ORYSJ (Q0IP28), 
LAC2_AGABI  (Q12542), LAC2_ARATH  (O81081), LAC2_BOTFU  (Q96WM9), 
LAC2_ORYSJ  (Q8RYM9), LAC2_PLEOS  (Q12739), LAC2_PODAS  (P78722), 
LAC3_ARATH  (Q56YT0), LAC3_BOTFU  (Q96UM2), LAC3_ORYSJ  (Q941X2), 
LAC3_TRAVI  (Q99049), LAC4_ARATH  (O80434), LAC4_ORYSJ  (Q5N9X2), 
LAC5_ARATH  (Q9SIY8), LAC5_ORYSJ  (Q5N9W4), LAC6_ARATH  (Q9ZPY2), 
LAC6_ORYSJ  (Q5N7A3), LAC7_ARATH  (Q9SR40), LAC7_ORYSJ  (Q5N7B4), 
LAC8_ORYSJ  (Q0JHP8), LAC9_ORYSJ  (Q6Z8L2), MCO_STAAR   (Q6GIX3), 
MCO_STAAU   (Q69HT9), MCO_STAES   (Q8CQF6), MCO_STAHJ   (Q4LAB0), 
MMCO_MYCTU  (I6WZK7), PCOA_ECOLX  (Q47452), PHSA_STRAT  (Q53692)
» More

UniProtKB/Swiss-Prot
False negative sequences
19 sequences

LAC1_PHLRA  (Q01679), LAC1_THACU  (P56193), LAC1_TRAHI  (Q02497), 
LAC1_TRAMX  (D0VWU3), LAC1_TRAVI  (Q99044), LAC2_THACU  (Q02075), 
LAC2_TRAVE  (Q12718), LAC2_TRAVI  (Q99046), LAC3_THACU  (Q02079), 
LAC4_THACU  (Q02081), LAC4_TRAVE  (Q12719), LAC4_TRAVI  (Q99055), 
LAC5_TRAVE  (Q12717), LAC5_TRAVI  (Q99056), LAC8_ARATH  (Q9LFD2), 
LAC9_ARATH  (Q9LFD1), LACC_HALVD  (D4GPK6), LPR1_ARATH  (F4I4K5), 
LPR2_ARATH  (Q949X9)
» More

UniProtKB/Swiss-Prot
'Partial' sequences
5 sequences

LAC1B_CERUI (P85308), LAC1_GALSP  (P86351), LAC2D_CERUI (P85430), 
LAC2_CERUI  (P85149), MCOL1_ZINVI (P85414)
» More

UniProtKB/Swiss-Prot
False positive sequences
3 sequences

SNAI3_HUMAN (Q3KNW1), SNAI3_MOUSE (Q9QY31), TMUB1_DANRE (Q6P135)

		
PDB
[Detailed view]
43 PDB

1AOZ; 1ASO; 1ASP; 1ASQ; 1GW0; 1KCW; 1KV7; 1N68; 1PF3; 1ZPU; 2FQD; 2FQE; 2FQF; 2FQG; 2IH8; 2IH9; 2J5W; 2Q9O; 2YXV; 2YXW; 3DKH; 3FU7; 3FU8; 3FU9; 3GYR; 3NSD; 3NSF; 3NSY; 3OD3; 3PAU; 3PAV; 3QPK; 3QQX; 4E9Q; 4E9R; 4E9S; 4E9T; 4EF3; 4EJX; 4ENZ; 4HAK; 4HAL; 4NER
» More

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