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Entry: PS00080
General information about the entry
Entry nameMULTICOPPER_OXIDASE2
Accession numberPS00080
Entry typePATTERN
DateAPR-1990 (CREATED); OCT-1993 (DATA UPDATE); DEC-2011 (INFO UPDATE).
PROSITE DocumentationPDOC00076
Name and characterization of the entry
DescriptionMulticopper oxidases signature 2.
PatternH-C-H-x(3)-H-x(3)-[AG]-[LM].
Numerical results
  • UniProtKB/Swiss-Prot release number: 01, total number of sequence entries in that release: 534242.
  • Total number of hits in UniProtKB/Swiss-Prot: 91 hits in 91 different sequences
  • Number of hits on proteins that are known to belong to the set under consideration: 88 hits in 88 different sequences
  • Number of hits on proteins that could potentially belong to the set under consideration: 0 hits in 0 different sequences
  • Number of false hits (on unrelated proteins): 3 hits in 3 different sequences
  • Number of known missed hits: 16
  • Number of partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences: 5
  • Precision (true hits / (true hits + false positives)): 96.70 %
  • Recall (true hits / (true hits + false negatives)): 84.62 %
Comments
  • Taxonomic range: Eukaryotes, Prokaryotes (Bacteria)
  • Maximum known number of repetitions of the pattern in a single protein: 1
  • `Interesting' site in the pattern: 1,copper_3
  • `Interesting' site in the pattern: 2,copper_1
  • `Interesting' site in the pattern: 3,copper_3
  • `Interesting' site in the pattern: 5,copper_1
  • `Interesting' site in the pattern: 8,copper_1
  • VERSION: 1
Cross-references
UniProtKB/Swiss-ProtTrue positive hits:
ASO_CUCMA   (P24792), ASO_CUCPM   (P37064), ASO_CUCSA   (P14133), 
ASO_TOBAC   (Q40588), CERU_HUMAN  (P00450), CERU_MOUSE  (Q61147), 
CERU_RAT    (P13635), CERU_SHEEP  (Q9XT27), COPA_PSESM  (P59571), 
COPA_PSEUB  (P12374), CUEO_ECO57  (Q8X947), CUEO_ECOLI  (P36649), 
CUEO_SALTI  (Q8Z9E1), CUEO_SALTY  (Q8ZRS2), CUEO_YERPE  (Q8ZBK0), 
FET3_CANAX  (P78591), FET3_CANGA  (Q96WT3), FET3_KLULA  (Q6CII3), 
FET3_YEAST  (P38993), FET5_YEAST  (P43561), FIO1_SCHPO  (Q09920), 
HEPH_HUMAN  (Q9BQS7), HEPH_MOUSE  (Q9Z0Z4), HEPH_RAT    (Q920H8), 
HPHL1_HUMAN (Q6MZM0), HPHL1_MOUSE (Q3V1H3), LAC10_ARATH (Q6ID18), 
LAC10_ORYSJ (Q10ND7), LAC11_ARATH (Q8VZA1), LAC11_ORYSJ (Q0DHL5), 
LAC12_ARATH (Q9FLB5), LAC12_ORYSJ (Q0DHL2), LAC13_ARATH (Q9LYQ2), 
LAC14_ARATH (Q9FY79), LAC14_ORYSJ (Q69L99), LAC15_ARATH (Q84J37), 
LAC15_ORYSJ (Q339K6), LAC16_ARATH (Q1PDH6), LAC16_ORYSJ (Q7XE50), 
LAC17_ARATH (Q9FJD5), LAC17_ORYSJ (Q2RBK2), LAC18_ORYSI (A2XCN6), 
LAC18_ORYSJ (Q53LU4), LAC19_ORYSI (A2Y9C5), LAC19_ORYSJ (Q2R0L2), 
LAC1_AGABI  (Q12541), LAC1_ARATH  (Q9LMS3), LAC1_BOTFU  (Q12570), 
LAC1_CRYPA  (Q03966), LAC1_EMENI  (P17489), LAC1_MELAO  (Q70KY3), 
LAC1_NEUCR  (P06811), LAC1_ORYSJ  (Q5ZCW1), LAC1_PLEOS  (Q12729), 
LAC20_ORYSI (A2Y9C2), LAC20_ORYSJ (Q2R0L0), LAC21_ORYSJ (Q2QZ80), 
LAC22_ORYSJ (Q0IQU1), LAC23_ORYSJ (Q2QYS3), LAC24_ORYSJ (Q2QUN2), 
LAC25_ORYSJ (Q0IP28), LAC2_AGABI  (Q12542), LAC2_ARATH  (O81081), 
LAC2_BOTFU  (Q96WM9), LAC2_ORYSJ  (Q8RYM9), LAC2_PLEOS  (Q12739), 
LAC2_PODAS  (P78722), LAC3_ARATH  (Q56YT0), LAC3_BOTFU  (Q96UM2), 
LAC3_ORYSJ  (Q941X2), LAC3_TRAVI  (Q99049), LAC4_ARATH  (O80434), 
LAC4_ORYSJ  (Q5N9X2), LAC5_ARATH  (Q9SIY8), LAC5_ORYSJ  (Q5N9W4), 
LAC6_ARATH  (Q9ZPY2), LAC6_ORYSJ  (Q5N7A3), LAC7_ARATH  (Q9SR40), 
LAC7_ORYSJ  (Q5N7B4), LAC8_ORYSJ  (Q0JHP8), LAC9_ORYSJ  (Q6Z8L2), 
MCO_STAAR   (Q6GIX3), MCO_STAAU   (Q69HT9), MCO_STAES   (Q8CQF6), 
MCO_STAHJ   (Q4LAB0), PCOA_ECOLX  (Q47452), PHSA_STRAT  (Q53692), 
YD506_YEAST (Q04399)
False negative hits (sequences which belong to the set under consideration, but which have not been picked up by the pattern or profile):
LAC1_PHLRA  (Q01679), LAC1_THACU  (P56193), LAC1_TRAHI  (Q02497), 
LAC1_TRAMX  (D0VWU3), LAC1_TRAVI  (Q99044), LAC2_THACU  (Q02075), 
LAC2_TRAVE  (Q12718), LAC2_TRAVI  (Q99046), LAC3_THACU  (Q02079), 
LAC4_THACU  (Q02081), LAC4_TRAVE  (Q12719), LAC4_TRAVI  (Q99055), 
LAC5_TRAVE  (Q12717), LAC5_TRAVI  (Q99056), LAC8_ARATH  (Q9LFD2), 
LAC9_ARATH  (Q9LFD1)
`Potential' hits (partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences):
LAC1B_CERUI (P85308), LAC1_GALSP  (P86351), LAC2D_CERUI (P85430), 
LAC2_CERUI  (P85149), MCOL1_ZINEL (P85414)
False positive hits (sequences which do not belong to the set under consideration):
SNAI3_HUMAN (Q3KNW1), SNAI3_MOUSE (Q9QY31), TMUB1_DANRE (Q6P135)
Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:

[Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format]

Retrieve the sequence logo from the alignment

PDB
[Detailed view]		1AOZ; 1ASO; 1ASP; 1ASQ; 1GW0; 1KCW; 1KV7; 1N68; 1PF3; 1ZPU; 2FQD; 2FQE; 2FQF; 2FQG; 2IH8; 2IH9; 2J5W; 2Q9O; 2YXV; 2YXW; 3DKH; 3FU7; 3FU8; 3FU9; 3GYR; 3NSD; 3NSF; 3NSY; 3OD3; 3PAU; 3PAV; 3QPK;

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