Entry: PS00170

Forthcoming changes to the profile format
General information about the entry

Entry name [info] CSA_PPIASE_1
Accession [info] PS00170
Entry type [info] PATTERN
Date [info] APR-1990 (CREATED); DEC-2004 (DATA UPDATE); JUL-2014 (INFO UPDATE).
PROSITE Doc. [info] PDOC00154

Name and characterization of the entry

Description [info] Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature.
Pattern [info]
[FY]-x(2)-[STCNLVA]-x-[FV]-H-[RH]-[LIVMNS]-[LIVM]-x(2)-F-[LIVM]-x-Q-
[AGFT]-G.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2014_09 which contains 546'439 sequence entries.


Total number of hits 251 in 251 different sequences
Number of true positive hits 251 in 251 different sequences
Number of 'unknown' hits
Number of false positive hits
Number of false negative sequences 60
Number of 'partial' sequences 5
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 80.71 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
251 sequences

CP18A_ARATH (Q9LPC7), CP18B_ARATH (Q9SIH1), CP18C_ARATH (P34790), 
CP18D_ARATH (Q42406), CP19A_ARATH (Q38900), CP19B_ARATH (Q9SKQ0), 
CP19C_ARATH (Q38867), CP19D_ARATH (Q8LDP4), CP20A_ARATH (Q9SP02), 
CP20B_ARATH (Q9ASS6), CP20C_ARATH (P34791), CP21A_ARATH (O49605), 
CP21B_ARATH (Q8L8W5), CPY57_ARATH (Q6Q152), CPY65_ARATH (Q9FJX0), 
CWC27_ASPFU (Q4WE62), CWC27_BOVIN (Q17QX9), CWC27_DANRE (Q7ZW86), 
CWC27_EMENI (Q5AUG9), CWC27_GIBZE (Q4IPB3), CWC27_HUMAN (Q6UX04), 
CWC27_MACFA (Q4R713), CWC27_MOUSE (Q3TKY6), CWC27_NEUCR (Q7SBX8), 
CWC27_PONAB (Q5R7W3), CWC27_RAT   (Q5XIB2), CWC27_RHIO9 (P0C1J2), 
CWC27_USTMA (Q4P7H2), CWC27_XENLA (Q6GLX7), CYP10_CAEEL (P52017), 
CYP11_CAEEL (P52018), CYP11_RHIO9 (P0C1I9), CYP15_RHIO9 (P0C1J0), 
CYP1_BRUMA  (Q27450), CYP1_CAEEL  (P52009), CYP1_SOYBN  (Q8W171), 
CYP2_CAEEL  (P52010), CYP3_CAEEL  (P52011), CYP40_ARATH (Q9C566), 
CYP4_CAEEL  (P52012), CYP5_CAEEL  (P52013), CYP5_RHIO9  (P0C1I7), 
CYP63_ARATH (Q9LY75), CYP6_CAEEL  (P52014), CYP6_RHIO9  (P0C1I8), 
CYP7_CAEEL  (P52015), CYP7_SCHPO  (O42941), CYP7_YEAST  (P47103), 
CYP8_CAEEL  (P52016), CYP9_CAEEL  (Q09637), CYP9_SCHPO  (O74942), 
CYPB_VICFA  (Q41651), CYPB_YEAST  (P23285), CYPC_YEAST  (P25719), 
CYPD_YEAST  (P35176), CYPE_DICDI  (Q9NI62), CYPH_ALLCE  (P34887), 
CYPH_BRANA  (P24525), CYPH_CATRO  (Q39613), CYPH_ENCCU  (Q8SRE1), 
CYPH_LUPLU  (O49886), CYPH_MAIZE  (P21569), CYPH_NEUCR  (P10255), 
CYPH_SCHPO  (P18253), CYPH_SOLLC  (P21568), CYPH_UROFA  (O00060), 
CYPH_YEAST  (P14832), CYPR_CALVI  (P28517), CYPR_DROME  (P15425), 
CYPX_USEUD  (P35627), NKTR_HUMAN  (P30414), NKTR_MOUSE  (P30415), 
PAL4A_HUMAN (Q9Y536), PAL4D_HUMAN (F5H284), PAL4G_HUMAN (A2BFH1), 
PPI1_BRUA2  (Q2YPY5), PPI1_BRUAB  (Q57D43), PPI1_BRUME  (Q8YHB5), 
PPI1_BRUSU  (Q8G0J9), PPI1_STAEQ  (Q5HQK8), PPI1_STAES  (Q8CT84), 
PPI1_STAS1  (Q49W93), PPI1_SYNY3  (P72704), PPI2_SYNY3  (P73789), 
PPIA1_RHIO9 (P0C1H7), PPIA2_RHIO9 (P0C1H8), PPIA_ACIAD  (P42693), 
PPIA_AOTTR  (Q6DTV9), PPIA_BLAGE  (P54985), PPIA_BOVIN  (P62935), 
PPIA_CANAL  (P22011), PPIA_CHLAE  (P62938), PPIA_CRIGR  (P14851), 
PPIA_DICD3  (O53021), PPIA_DICDI  (Q54SM3), PPIA_DROME  (P25007), 
PPIA_ECHGR  (P14088), PPIA_ECO57  (P0AFL5), PPIA_ECOL6  (P0AFL4), 
PPIA_ECOLI  (P0AFL3), PPIA_FELCA  (Q8HXS3), PPIA_GORGO  (Q0ZQL0), 
PPIA_HELPJ  (Q9ZJH5), PPIA_HELPY  (O25982), PPIA_HEMPU  (P91791), 
PPIA_HUMAN  (P62937), PPIA_HYLLA  (Q0ZQK8), PPIA_HYLSY  (Q0ZQK6), 
PPIA_MACMU  (P62940), PPIA_MOUSE  (P17742), PPIA_MYCBO  (P65763), 
PPIA_MYCLE  (Q9CDE9), PPIA_MYCTO  (P9WHW2), PPIA_MYCTU  (P9WHW3), 
PPIA_NEOCA  (P84343), PPIA_NOMLE  (Q0ZQK7), PPIA_PANPA  (Q0ZQL2), 
PPIA_PANTR  (Q0ZQL1), PPIA_PAPAN  (P62941), PPIA_PARPR  (O00845), 
PPIA_PIG    (P62936), PPIA_PONPY  (Q5R8S7), PPIA_PSEAE  (Q59641), 
PPIA_RABIT  (Q9TTC6), PPIA_RAT    (P10111), PPIA_SAGOE  (Q0ZQK3), 
PPIA_SALTY  (P20753), PPIA_SCHMA  (Q26565), PPIA_STRAQ  (Q06118), 
PPIB1_RHIO9 (P0C1H9), PPIB2_RHIO9 (P0C1I0), PPIB_ARTBE  (O93826), 
PPIB_ASPFU  (Q4WP12), PPIB_ASPNG  (Q8X166), PPIB_ASPOR  (Q2UGK2), 
PPIB_BACSU  (P35137), PPIB_BOVIN  (P80311), PPIB_CHICK  (P24367), 
PPIB_CRYNB  (P0CP79), PPIB_CRYNJ  (P0CP78), PPIB_DICDI  (Q9TW32), 
PPIB_ECOLI  (P23869), PPIB_EMENI  (Q5B4R3), PPIB_GIBZE  (Q4I5R9), 
PPIB_HAEIN  (P44499), PPIB_HUMAN  (P23284), PPIB_MOUSE  (P24369), 
PPIB_NEUCR  (Q7S7Z6), PPIB_ORPSP  (Q01490), PPIB_RAT    (P24368), 
PPIB_SCHJA  (Q27774), PPIB_SCHMA  (Q26551), PPIB_SCHPO  (O94273), 
PPIB_STRAQ  (P77949), PPIB_STRAT  (P83221), PPIB_TREPA  (O66105), 
PPIB_YARLI  (Q6C4W6), PPIC_BOVIN  (Q08E11), PPIC_HUMAN  (P45877), 
PPIC_MOUSE  (P30412), PPID_AMAMU  (Q5U8Z7), PPID_ASHGO  (Q75A33), 
PPID_ASPFU  (Q4WIF3), PPID_ASPOR  (Q2U0E0), PPID_BOVIN  (P26882), 
PPID_CANAL  (Q5ACI8), PPID_CANGA  (Q6FNU6), PPID_DEBHA  (Q6BXZ7), 
PPID_DICDI  (Q9UA41), PPID_EMENI  (Q5B4E7), PPID_GIBZE  (Q4HXF6), 
PPID_HUMAN  (Q08752), PPID_KLULA  (Q6CL78), PPID_MOUSE  (Q9CR16), 
PPID_NEUCR  (Q9P3X9), PPID_RAT    (Q6DGG0), PPID_RHIO9  (P0C1I1), 
PPID_SCHPO  (Q11004), PPID_USTMA  (Q4P0V4), PPID_YARLI  (Q6CBP4), 
PPID_YEAST  (P53691), PPIE_BOVIN  (A4FV72), PPIE_DROME  (Q9V3G3), 
PPIE_HAECO  (Q4G338), PPIE_HUMAN  (Q9UNP9), PPIE_MOUSE  (Q9QZH3), 
PPIE_PONAB  (Q5R723), PPIE_RHIO9  (P0C1I2), PPIE_SCHJA  (Q26516), 
PPIE_SCHMA  (Q26548), PPIF_BOVIN  (P30404), PPIF_HUMAN  (P30405), 
PPIF_MOUSE  (Q99KR7), PPIF_RAT    (P29117), PPIG_HUMAN  (Q13427), 
PPIG_MOUSE  (A2AR02), PPIG_RAT    (O55035), PPIH_ASPFU  (Q4WCM6), 
PPIH_ASPOR  (Q2TZ33), PPIH_BOVIN  (Q0P5D0), PPIH_CRYNB  (P0CP83), 
PPIH_CRYNJ  (P0CP82), PPIH_EMENI  (Q5AQL0), PPIH_GIBZE  (Q4IPH4), 
PPIH_HUMAN  (O43447), PPIH_MOUSE  (Q9D868), PPIH_NEUCR  (Q7SG06), 
PPIH_RHIO9  (P0C1I3), PPIH_SCHPO  (O74729), PPIH_USTMA  (Q4P6X6), 
PPIL1_ASPFU (Q4WCR3), PPIL1_ASPNG (Q8X191), PPIL1_ASPOR (Q2U6U0), 
PPIL1_BOVIN (Q5E992), PPIL1_CRYNB (P0CP85), PPIL1_CRYNJ (P0CP84), 
PPIL1_EMENI (Q5ASQ0), PPIL1_GIBZE (Q4I1Y1), PPIL1_HUMAN (Q9Y3C6), 
PPIL1_MOUSE (Q9D0W5), PPIL1_NEUCR (Q7SF72), PPIL1_RHIO9 (P0C1I4), 
PPIL1_SCHPO (P87051), PPIL2_ASPFU (Q4WVU5), PPIL2_ASPOR (Q2U5W8), 
PPIL2_CRYNB (P0CP91), PPIL2_CRYNJ (P0CP90), PPIL2_EMENI (Q5AXT6), 
PPIL2_GIBZE (Q4IBK5), PPIL2_HUMAN (Q13356), PPIL2_MOUSE (Q9D787), 
PPIL2_NEUCR (Q7RXA6), PPIL2_RHIO9 (P0C1J1), PPIL2_SCHPO (Q09928), 
PPIL2_USTMA (Q4P555), PPIL3_CHICK (Q5ZLV2), PPIL3_CRYNB (P0CP87), 
PPIL3_CRYNJ (P0CP86), PPIL3_DICDI (Q54E95), PPIL3_EMENI (Q5BAH7), 
PPIL3_GIBZE (Q4IPB8), PPIL3_HUMAN (Q9H2H8), PPIL3_MOUSE (Q9D6L8), 
PPIL3_NEUCR (Q6MWS8), PPIL3_RAT   (Q812D3), PPI_LOTGI   (B3A0R0), 
PPI_SYNE7   (P29820), RBP2_BOVIN  (P48820), RBP2_HUMAN  (P49792), 
RBP2_MOUSE  (Q9ERU9), RBP2_PANTR  (H2QII6)
» More

UniProtKB/Swiss-Prot
False negative sequences
60 sequences

BPPI_STRP6  (Q5XAQ1), CP21C_ARATH (Q94A16), CP21D_ARATH (Q9C835), 
CP26A_ARATH (Q9LIK6), CP26B_ARATH (F4HTT6), CPY28_ARATH (O65220), 
CPY71_ARATH (Q8W4D0), CWC27_ASHGO (Q75A74), CWC27_CRYNB (P0CP93), 
CWC27_CRYNJ (P0CP92), CWC27_DEBHA (Q6BWH6), CWC27_YARLI (Q6CGK4), 
CWC27_YEAST (Q02770), CYP22_ARATH (Q9ZVJ4), CYP23_ARATH (Q8LDR3), 
CYP37_ARATH (P82869), CYP38_ARATH (Q9SSA5), CYP59_ARATH (Q6Q151), 
CYP8_YEAST  (P53728), CYP95_ARATH (Q8RWY7), CYP9_CAEBR  (A8X8D0), 
CYPR_YEAST  (P25334), PPI1_STAA3  (Q2FIC1), PPI1_STAA8  (Q2FZU9), 
PPI1_STAAB  (Q2YWT2), PPI1_STAAC  (Q5HHD1), PPI1_STAAM  (Q99VD4), 
PPI1_STAAN  (Q7A6I1), PPI1_STAAR  (Q6GID4), PPI1_STAAS  (Q6GAX2), 
PPI1_STAAW  (Q7A1C0), PPI1_STAHJ  (Q4L4W9), PPI3_SYNY3  (Q55118), 
PPIB_MYCLE  (P46697), PPIB_MYCTO  (P9WHW0), PPIB_MYCTU  (P9WHW1), 
PPID_CRYNB  (P0CP81), PPID_CRYNJ  (P0CP80), PPIL3_RHIO9 (P0C1I5), 
PPIL3_USTMA (Q4PCH8), PPIL4_ASPFU (Q4WAQ9), PPIL4_ASPOR (Q2U256), 
PPIL4_CRYNB (P0CP89), PPIL4_CRYNJ (P0CP88), PPIL4_EMENI (Q5ARI5), 
PPIL4_GIBZE (Q4IE79), PPIL4_HUMAN (Q8WUA2), PPIL4_MOUSE (Q9CXG3), 
PPIL4_NEUCR (Q871A4), PPIL4_RHIO9 (P0C1I6), PPIL4_SCHPO (Q9UUE4), 
PPIL4_USTMA (P0C196), PPIL6_BOVIN (Q1RMP7), PPIL6_HUMAN (Q8IXY8), 
PPIL6_MOUSE (Q9D6D8), PPWD1_BOVIN (Q29RZ2), PPWD1_HUMAN (Q96BP3), 
PPWD1_MOUSE (Q8CEC6), PPWD1_PONAB (Q5NVL7), TLP40_SPIOL (O49939)
» More

UniProtKB/Swiss-Prot
'Partial' sequences
5 sequences

CYPH_BETPN  (P81531), PPIA_NAEFO  (P84342), PPIA_PENGL  (P85444), 
PPIM_MAIZE  (Q10724), TLP20_SPIOL (P82536)
» More

PDB
[Detailed view]
140 PDB

1A33; 1A58; 1AK4; 1AWQ; 1AWR; 1AWU; 1AWV; 1BCK; 1C5F; 1CLH; 1CWA; 1CWB; 1CWC; 1CWF; 1CWH; 1CWI; 1CWJ; 1CWK; 1CWL; 1CWM; 1CWO; 1CYN; 1DYW; 1E3B; 1E8K; 1FGL; 1H0P; 1IHG; 1IIP; 1IST; 1J2A; 1LOP; 1M63; 1M9C; 1M9D; 1M9E; 1M9F; 1M9X; 1M9Y; 1MF8; 1MIK; 1MZW; 1NMK; 1OCA; 1QOI; 1RMH; 1V9T; 1VAI; 1VBS; 1VBT; 1VDN; 1W74; 1W8L; 1W8M; 1W8V; 1XWN; 1XYH; 1YND; 1ZKC; 1ZKF; 1ZMF; 2ALF; 2BIT; 2BIU; 2CK1; 2CMT; 2CPL; 2CYH; 2ESL; 2GW2; 2HE9; 2HQ6; 2IGV; 2IGW; 2K7N; 2NUL; 2OJU; 2OK3; 2R99; 2RMA; 2RMB; 2RMC; 2RS4; 2WFJ; 2WLW; 2X25; 2X2A; 2X2C; 2X2D; 2X7K; 2XGY; 2Z6W; 3CYH; 3CYS; 3ICH; 3ICI; 3K0M; 3K0N; 3K0O; 3K0P; 3K0Q; 3K2C; 3ODI; 3ODL; 3QYU; 3R49; 3R4G; 3R54; 3R56; 3R57; 3R59; 3RCF; 3RCG; 3RCI; 3RCK; 3RCL; 3RD9; 3RDA; 3RDB; 3RDC; 3RDD; 4CYH; 4DGA; 4DGB; 4DGC; 4DGD; 4DGE; 4I9Y; 4IPZ; 4J58; 4J59; 4J5A; 4J5B; 4J5C; 4J5D; 4J5E; 4LQW; 4O8H; 4O8I; 5CYH
» More

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