Entry: PS00170

General information about the entry

Entry name [info] CSA_PPIASE_1
Accession [info] PS00170
Entry type [info] PATTERN
Date [info] APR-1990 (CREATED); DEC-2004 (DATA UPDATE); JUN-2015 (INFO UPDATE).
PROSITE Doc. [info] PDOC00154

Name and characterization of the entry

Description [info] Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature.
Pattern [info]
[FY]-x(2)-[STCNLVA]-x-[FV]-H-[RH]-[LIVMNS]-[LIVM]-x(2)-F-[LIVM]-x-Q-
[AGFT]-G.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2015_08 which contains 320'201 sequence entries.


Total number of hits 251 in 251 different sequences
Number of true positive hits 251 in 251 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 60
Number of 'partial' sequences 5
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 80.71 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
251 sequences

CP18A_ARATH (Q9LPC7), CP18B_ARATH (Q9SIH1), CP18C_ARATH (P34790), 
CP18D_ARATH (Q42406), CP19A_ARATH (Q38900), CP19B_ARATH (Q9SKQ0), 
CP19C_ARATH (Q38867), CP19D_ARATH (Q8LDP4), CP20A_ARATH (Q9SP02), 
CP20C_ARATH (P34791), CP21A_ARATH (O49605), CP21B_ARATH (Q8L8W5), 
CPY57_ARATH (Q6Q152), CWC27_ASPFU (Q4WE62), CWC27_BOVIN (Q17QX9), 
CWC27_DANRE (Q7ZW86), CWC27_EMENI (Q5AUG9), CWC27_GIBZE (Q4IPB3), 
CWC27_HUMAN (Q6UX04), CWC27_MACFA (Q4R713), CWC27_MOUSE (Q3TKY6), 
CWC27_NEUCR (Q7SBX8), CWC27_PONAB (Q5R7W3), CWC27_RAT   (Q5XIB2), 
CWC27_RHIO9 (P0C1J2), CWC27_USTMA (Q4P7H2), CWC27_XENLA (Q6GLX7), 
CYP10_CAEEL (P52017), CYP11_CAEEL (P52018), CYP11_RHIO9 (P0C1I9), 
CYP15_RHIO9 (P0C1J0), CYP1_BRUMA  (Q27450), CYP1_CAEEL  (P52009), 
CYP1_SOYBN  (Q8W171), CYP2_CAEEL  (P52010), CYP3_CAEEL  (P52011), 
CYP40_ARATH (Q9C566), CYP5_CAEEL  (P52013), CYP5_RHIO9  (P0C1I7), 
CYP63_ARATH (Q9LY75), CYP6_CAEEL  (P52014), CYP6_RHIO9  (P0C1I8), 
CYP7_CAEEL  (P52015), CYP7_SCHPO  (O42941), CYP7_YEAST  (P47103), 
CYP8_CAEEL  (P52016), CYP9_CAEEL  (Q09637), CYP9_SCHPO  (O74942), 
CYPB_VICFA  (Q41651), CYPB_YEAST  (P23285), CYPC_YEAST  (P25719), 
CYPD_YEAST  (P35176), CYPE_DICDI  (Q9NI62), CYPH_ALLCE  (P34887), 
CYPH_BRANA  (P24525), CYPH_CATRO  (Q39613), CYPH_ENCCU  (Q8SRE1), 
CYPH_LUPLU  (O49886), CYPH_MAIZE  (P21569), CYPH_NEUCR  (P10255), 
CYPH_SCHPO  (P18253), CYPH_SOLLC  (P21568), CYPH_UROFA  (O00060), 
CYPH_YEAST  (P14832), CYPR_CALVI  (P28517), CYPR_DROME  (P15425), 
CYPX_USEUD  (P35627), NKTR_HUMAN  (P30414), NKTR_MOUSE  (P30415), 
PAL4A_HUMAN (Q9Y536), PAL4D_HUMAN (F5H284), PAL4G_HUMAN (A2BFH1), 
PNSL5_ARATH (Q9ASS6), PPI1_BRUA2  (Q2YPY5), PPI1_BRUAB  (Q57D43), 
PPI1_BRUME  (Q8YHB5), PPI1_BRUSU  (Q8G0J9), PPI1_STAEQ  (Q5HQK8), 
PPI1_STAES  (Q8CT84), PPI1_STAS1  (Q49W93), PPI1_SYNY3  (P72704), 
PPI2_SYNY3  (P73789), PPIA1_RHIO9 (P0C1H7), PPIA2_RHIO9 (P0C1H8), 
PPIA_ACIAD  (P42693), PPIA_AOTTR  (Q6DTV9), PPIA_BLAGE  (P54985), 
PPIA_BOVIN  (P62935), PPIA_CANAL  (P22011), PPIA_CHLAE  (P62938), 
PPIA_CRIGR  (P14851), PPIA_DICD3  (O53021), PPIA_DICDI  (Q54SM3), 
PPIA_DROME  (P25007), PPIA_ECHGR  (P14088), PPIA_ECO57  (P0AFL5), 
PPIA_ECOL6  (P0AFL4), PPIA_ECOLI  (P0AFL3), PPIA_FELCA  (Q8HXS3), 
PPIA_GORGO  (Q0ZQL0), PPIA_HELPJ  (Q9ZJH5), PPIA_HELPY  (O25982), 
PPIA_HEMPU  (P91791), PPIA_HUMAN  (P62937), PPIA_HYLLA  (Q0ZQK8), 
PPIA_MACMU  (P62940), PPIA_MOUSE  (P17742), PPIA_MYCBO  (P65763), 
PPIA_MYCLE  (Q9CDE9), PPIA_MYCTO  (P9WHW2), PPIA_MYCTU  (P9WHW3), 
PPIA_NEOCA  (P84343), PPIA_NOMLE  (Q0ZQK7), PPIA_PANPA  (Q0ZQL2), 
PPIA_PANTR  (Q0ZQL1), PPIA_PAPAN  (P62941), PPIA_PARPR  (O00845), 
PPIA_PIG    (P62936), PPIA_PONPY  (Q5R8S7), PPIA_PSEAE  (Q59641), 
PPIA_RABIT  (Q9TTC6), PPIA_RAT    (P10111), PPIA_SAGOE  (Q0ZQK3), 
PPIA_SALTY  (P20753), PPIA_SCHMA  (Q26565), PPIA_STRAQ  (Q06118), 
PPIA_SYMSY  (Q0ZQK6), PPIB1_RHIO9 (P0C1H9), PPIB2_RHIO9 (P0C1I0), 
PPIB_ARTBE  (O93826), PPIB_ASPFU  (Q4WP12), PPIB_ASPNG  (Q8X166), 
PPIB_ASPOR  (Q2UGK2), PPIB_BACSU  (P35137), PPIB_BOVIN  (P80311), 
PPIB_CHICK  (P24367), PPIB_CRYNB  (P0CP79), PPIB_CRYNJ  (P0CP78), 
PPIB_DICDI  (Q9TW32), PPIB_ECOLI  (P23869), PPIB_EMENI  (Q5B4R3), 
PPIB_GIBZE  (Q4I5R9), PPIB_HAEIN  (P44499), PPIB_HUMAN  (P23284), 
PPIB_MOUSE  (P24369), PPIB_NEUCR  (Q7S7Z6), PPIB_ORPSP  (Q01490), 
PPIB_RAT    (P24368), PPIB_SCHJA  (Q27774), PPIB_SCHMA  (Q26551), 
PPIB_SCHPO  (O94273), PPIB_STRAQ  (P77949), PPIB_STRAT  (P83221), 
PPIB_TREPA  (O66105), PPIB_YARLI  (Q6C4W6), PPIC_BOVIN  (Q08E11), 
PPIC_HUMAN  (P45877), PPIC_MOUSE  (P30412), PPID_AMAMU  (Q5U8Z7), 
PPID_ASHGO  (Q75A33), PPID_ASPFU  (Q4WIF3), PPID_ASPOR  (Q2U0E0), 
PPID_BOVIN  (P26882), PPID_CANAL  (Q5ACI8), PPID_CANGA  (Q6FNU6), 
PPID_DEBHA  (Q6BXZ7), PPID_DICDI  (Q9UA41), PPID_EMENI  (Q5B4E7), 
PPID_GIBZE  (Q4HXF6), PPID_HUMAN  (Q08752), PPID_KLULA  (Q6CL78), 
PPID_MOUSE  (Q9CR16), PPID_NEUCR  (Q9P3X9), PPID_RAT    (Q6DGG0), 
PPID_RHIO9  (P0C1I1), PPID_SCHPO  (Q11004), PPID_USTMA  (Q4P0V4), 
PPID_YARLI  (Q6CBP4), PPID_YEAST  (P53691), PPIE_BOVIN  (A4FV72), 
PPIE_DROME  (Q9V3G3), PPIE_HAECO  (Q4G338), PPIE_HUMAN  (Q9UNP9), 
PPIE_MOUSE  (Q9QZH3), PPIE_PONAB  (Q5R723), PPIE_RHIO9  (P0C1I2), 
PPIE_SCHJA  (Q26516), PPIE_SCHMA  (Q26548), PPIF_BOVIN  (P30404), 
PPIF_HUMAN  (P30405), PPIF_MOUSE  (Q99KR7), PPIF_RAT    (P29117), 
PPIG_HUMAN  (Q13427), PPIG_MOUSE  (A2AR02), PPIG_RAT    (O55035), 
PPIH_ASPFU  (Q4WCM6), PPIH_ASPOR  (Q2TZ33), PPIH_BOVIN  (Q0P5D0), 
PPIH_CRYNB  (P0CP83), PPIH_CRYNJ  (P0CP82), PPIH_EMENI  (Q5AQL0), 
PPIH_GIBZE  (Q4IPH4), PPIH_HUMAN  (O43447), PPIH_MOUSE  (Q9D868), 
PPIH_NEUCR  (Q7SG06), PPIH_RHIO9  (P0C1I3), PPIH_SCHPO  (O74729), 
PPIH_USTMA  (Q4P6X6), PPIL1_ASPFU (Q4WCR3), PPIL1_ASPNG (Q8X191), 
PPIL1_ASPOR (Q2U6U0), PPIL1_BOVIN (Q5E992), PPIL1_CRYNB (P0CP85), 
PPIL1_CRYNJ (P0CP84), PPIL1_EMENI (Q5ASQ0), PPIL1_GIBZE (Q4I1Y1), 
PPIL1_HUMAN (Q9Y3C6), PPIL1_MOUSE (Q9D0W5), PPIL1_NEUCR (Q7SF72), 
PPIL1_RHIO9 (P0C1I4), PPIL1_SCHPO (P87051), PPIL2_ARATH (Q9FJX0), 
PPIL2_ASPFU (Q4WVU5), PPIL2_ASPOR (Q2U5W8), PPIL2_CAEEL (P52012), 
PPIL2_CRYNB (P0CP91), PPIL2_CRYNJ (P0CP90), PPIL2_EMENI (Q5AXT6), 
PPIL2_GIBZE (Q4IBK5), PPIL2_HUMAN (Q13356), PPIL2_MOUSE (Q9D787), 
PPIL2_NEUCR (Q7RXA6), PPIL2_RHIO9 (P0C1J1), PPIL2_SCHPO (Q09928), 
PPIL2_USTMA (Q4P555), PPIL3_CHICK (Q5ZLV2), PPIL3_CRYNB (P0CP87), 
PPIL3_CRYNJ (P0CP86), PPIL3_DICDI (Q54E95), PPIL3_EMENI (Q5BAH7), 
PPIL3_GIBZE (Q4IPB8), PPIL3_HUMAN (Q9H2H8), PPIL3_MOUSE (Q9D6L8), 
PPIL3_NEUCR (Q6MWS8), PPIL3_RAT   (Q812D3), PPI_LOTGI   (B3A0R0), 
PPI_SYNE7   (P29820), RBP2_BOVIN  (P48820), RBP2_HUMAN  (P49792), 
RBP2_MOUSE  (Q9ERU9), RBP2_PANTR  (H2QII6)
» More

UniProtKB/Swiss-Prot
False negative sequences
60 sequences

BPPI_STRP6  (Q5XAQ1), CP21C_ARATH (Q94A16), CP21D_ARATH (Q9C835), 
CP26A_ARATH (Q9LIK6), CP26B_ARATH (F4HTT6), CPY28_ARATH (O65220), 
CPY71_ARATH (Q8W4D0), CWC27_ASHGO (Q75A74), CWC27_CRYNB (P0CP93), 
CWC27_CRYNJ (P0CP92), CWC27_DEBHA (Q6BWH6), CWC27_YARLI (Q6CGK4), 
CWC27_YEAST (Q02770), CYP22_ARATH (Q9ZVJ4), CYP23_ARATH (Q8LDR3), 
CYP37_ARATH (P82869), CYP38_ARATH (Q9SSA5), CYP59_ARATH (Q6Q151), 
CYP8_YEAST  (P53728), CYP95_ARATH (Q8RWY7), CYP9_CAEBR  (A8X8D0), 
CYPR_YEAST  (P25334), PPI1_STAA3  (Q2FIC1), PPI1_STAA8  (Q2FZU9), 
PPI1_STAAB  (Q2YWT2), PPI1_STAAC  (Q5HHD1), PPI1_STAAM  (Q99VD4), 
PPI1_STAAN  (Q7A6I1), PPI1_STAAR  (Q6GID4), PPI1_STAAS  (Q6GAX2), 
PPI1_STAAW  (Q7A1C0), PPI1_STAHJ  (Q4L4W9), PPI3_SYNY3  (Q55118), 
PPIB_MYCLE  (P46697), PPIB_MYCTO  (P9WHW0), PPIB_MYCTU  (P9WHW1), 
PPID_CRYNB  (P0CP81), PPID_CRYNJ  (P0CP80), PPIL3_RHIO9 (P0C1I5), 
PPIL3_USTMA (Q4PCH8), PPIL4_ASPFU (Q4WAQ9), PPIL4_ASPOR (Q2U256), 
PPIL4_CRYNB (P0CP89), PPIL4_CRYNJ (P0CP88), PPIL4_EMENI (Q5ARI5), 
PPIL4_GIBZE (Q4IE79), PPIL4_HUMAN (Q8WUA2), PPIL4_MOUSE (Q9CXG3), 
PPIL4_NEUCR (Q871A4), PPIL4_RHIO9 (P0C1I6), PPIL4_SCHPO (Q9UUE4), 
PPIL4_USTMA (P0C196), PPIL6_BOVIN (Q1RMP7), PPIL6_HUMAN (Q8IXY8), 
PPIL6_MOUSE (Q9D6D8), PPWD1_BOVIN (Q29RZ2), PPWD1_HUMAN (Q96BP3), 
PPWD1_MOUSE (Q8CEC6), PPWD1_PONAB (Q5NVL7), TLP40_SPIOL (O49939)
» More

UniProtKB/Swiss-Prot
'Partial' sequences
5 sequences

CYPH_BETPN  (P81531), PPIA_NAEFO  (P84342), PPIA_PENGL  (P85444), 
PPIM_MAIZE  (Q10724), TLP20_SPIOL (P82536)
» More

PDB
[Detailed view]
144 PDB

1A33; 1A58; 1AK4; 1AWQ; 1AWR; 1AWU; 1AWV; 1BCK; 1C5F; 1CLH; 1CWA; 1CWB; 1CWC; 1CWF; 1CWH; 1CWI; 1CWJ; 1CWK; 1CWL; 1CWM; 1CWO; 1CYN; 1DYW; 1E3B; 1E8K; 1FGL; 1H0P; 1IHG; 1IIP; 1IST; 1J2A; 1LOP; 1M63; 1M9C; 1M9D; 1M9E; 1M9F; 1M9X; 1M9Y; 1MF8; 1MIK; 1MZW; 1NMK; 1OCA; 1QOI; 1RMH; 1V9T; 1VAI; 1VBS; 1VBT; 1VDN; 1W74; 1W8L; 1W8M; 1W8V; 1XWN; 1XYH; 1YND; 1ZKC; 1ZKF; 1ZMF; 2ALF; 2BIT; 2BIU; 2CK1; 2CMT; 2CPL; 2CYH; 2ESL; 2GW2; 2HE9; 2HQ6; 2IGV; 2IGW; 2K7N; 2MC9; 2MZU; 2NUL; 2OJU; 2OK3; 2R99; 2RMA; 2RMB; 2RMC; 2RS4; 2WFJ; 2WLW; 2X25; 2X2A; 2X2C; 2X2D; 2X7K; 2XGY; 2Z6W; 3CYH; 3CYS; 3ICH; 3ICI; 3K0M; 3K0N; 3K0O; 3K0P; 3K0Q; 3K2C; 3ODI; 3ODL; 3QYU; 3R49; 3R4G; 3R54; 3R56; 3R57; 3R59; 3RCF; 3RCG; 3RCI; 3RCK; 3RCL; 3RD9; 3RDA; 3RDB; 3RDC; 3RDD; 4CYH; 4DGA; 4DGB; 4DGC; 4DGD; 4DGE; 4I9Y; 4IPZ; 4J58; 4J59; 4J5A; 4J5B; 4J5C; 4J5D; 4J5E; 4LQW; 4O8H; 4O8I; 4R3E; 4TOT; 5CYH
» More

View entry in original PROSITE format
View entry in raw text format (no links)
Direct ScanProsite submission