Entry: PS00191

General information about the entry

Entry name [info] CYTOCHROME_B5_1
Accession [info] PS00191
Entry type [info] PATTERN
Date [info] APR-1990 (CREATED); DEC-2004 (DATA UPDATE); MAY-2016 (INFO UPDATE).
PROSITE Doc. [info] PDOC00170

Name and characterization of the entry

Description [info] Cytochrome b5 family, heme-binding domain signature.
Pattern [info]
[FY]-[LIVMK]-{I}-{Q}-H-P-[GA]-G.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2016_05 which contains 551'193 sequence entries.


Total number of hits 123 in 123 different sequences
Number of true positive hits 102 in 102 different sequences
Number of 'unknown' hits 0
Number of false positive hits 21 in 21 different sequences
Number of false negative sequences 74
Number of 'partial' sequences 2
Precision (true positives / (true positives + false positives)) 82.93 %
Recall (true positives / (true positives + false negatives)) 57.95 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info] 1
Site [info] heme_iron at position 5
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
102 sequences

ACO1_AJECA  (Q12618    ), ACO1_YEAST  (P21147    ), CYB2_WICAO  (P09437    ), 
CYB2_YEAST  (P00175    ), CYB52_SCHPO (Q9USM6    ), CYB5A_ARATH (Q9FDW8    ), 
CYB5B_ARATH (O48845    ), CYB5B_HUMAN (O43169    ), CYB5B_MOUSE (Q9CQX2    ), 
CYB5B_PONAB (Q5RDJ5    ), CYB5B_RAT   (P04166    ), CYB5C_ARATH (Q9ZNV4    ), 
CYB5D_ARATH (Q9ZWT2    ), CYB5E_ARATH (Q42342    ), CYB5L_MIMIV (Q5UR80    ), 
CYB5L_NEUCR (Q8X0J4    ), CYB5R_DROME (P19967    ), CYB5R_DROVI (P50266    ), 
CYB5S_TOBAC (P49099    ), CYB5_ALOSE  (P00168    ), CYB5_BOROF  (O04354    ), 
CYB5_BOVIN  (P00171    ), CYB5_BRAOB  (P40934    ), CYB5_CANTR  (Q874I5    ), 
CYB5_CHICK  (P00174    ), CYB5_CUSRE  (P49097    ), CYB5_DROME  (Q9V4N3    ), 
CYB5_HORSE  (P00170    ), CYB5_HUMAN  (P00167    ), CYB5_MORAP  (Q9Y706    ), 
CYB5_MOUSE  (P56395    ), CYB5_MUSDO  (P49096    ), CYB5_NEUCR  (Q9P5L0    ), 
CYB5_ORYSJ  (P49100    ), CYB5_PIG    (P00172    ), CYB5_RABIT  (P00169    ), 
CYB5_RAT    (P00173    ), CYB5_RHIST  (Q9HFV1    ), CYB5_TOBAC  (P49098    ), 
CYB5_YEAST  (P40312    ), CYBL_RHOGR  (P32953    ), CYP5F_ARATH (O22704    ), 
D4FAD_CHLRE (I2CYZ4    ), D4FAD_EUGGR (Q6WNG7    ), D5FAD_MORAP (O74212    ), 
D5FAD_REBSA (A4KDP0    ), DESAT_THAPS (Q4G2T3    ), DES_CHLRE   (Q2HWK7    ), 
FA2H_HUMAN  (Q7L5A8    ), FA2H_MACFA  (Q4R4P4    ), FA2H_MOUSE  (Q5MPP0    ), 
FA2H_RAT    (Q2LAM0    ), FAD5C_DICDI (Q1ZXQ5    ), IRC21_YEAST (Q04772    ), 
NB5R4_BOVIN (Q32LH7    ), NB5R4_DANRE (Q502I6    ), NB5R4_HUMAN (Q7L1T6    ), 
NB5R4_MOUSE (Q3TDX8    ), NB5R4_RAT   (Q68EJ0    ), NB5R4_XENTR (Q28CZ9    ), 
NIA1_ARATH  (P11832    ), NIA1_BRANA  (P39867    ), NIA1_HORVU  (P27967    ), 
NIA1_MAIZE  (P17571    ), NIA1_ORYSJ  (P16081    ), NIA1_PHAVU  (P39865    ), 
NIA1_SOYBN  (P54233    ), NIA1_TOBAC  (P11605    ), NIA2_ARATH  (P11035    ), 
NIA2_BRANA  (P39868    ), NIA2_HORVU  (P27969    ), NIA2_PHAVU  (P39866    ), 
NIA2_SOYBN  (P39870    ), NIA2_TOBAC  (P08509    ), NIA3_MAIZE  (P49102    ), 
NIA7_HORVU  (P27968    ), NIA_ASPNG   (P36858    ), NIA_BEABA   (P43100    ), 
NIA_BETPN   (P27783    ), NIA_CHLVU   (Q01170    ), NIA_CICIN   (P43101    ), 
NIA_CUCMA   (P17569    ), NIA_EMENI   (P22945    ), NIA_FUSOX   (P39863    ), 
NIA_LEPMC   (P36842    ), NIA_LOTJA   (P39869    ), NIA_NEUCR   (P08619    ), 
NIA_PETHY   (P36859    ), NIA_PHYIN   (P39864    ), NIA_PICAN   (P49050    ), 
NIA_SOLLC   (P17570    ), NIA_SPIOL   (P23312    ), NIA_USTMA   (Q05531    ), 
NIA_VOLCA   (P36841    ), RLF_ARATH   (Q9LXD1    ), SCS7_YEAST  (Q03529    ), 
SUOX_CHICK  (P07850    ), SUOX_DROME  (Q9VWP4    ), SUOX_HUMAN  (P51687    ), 
SUOX_MOUSE  (Q8R086    ), SUOX_RAT    (Q07116    ), YDAA_SCHPO  (Q10352    )
» more

UniProtKB/Swiss-Prot
False negative sequences
74 sequences

ACET6_CERPU (Q9LEN0    ), ACO1_SCHPO  (O94523    ), CB5D1_DANRE (Q567I9    ), 
CB5D1_HUMAN (Q6P9G0    ), CB5D1_MOUSE (Q5NCY3    ), CB5D1_PONAB (Q5R4Q5    ), 
CB5D1_XENLA (Q5PPR6    ), CB5D1_XENTR (Q0IHR1    ), CYB5_ECTSH  (P82291    ), 
D4FAD_DIALT (Q6VPV2    ), D4FAD_REBSA (A0PJ29    ), D4FAD_THRSP (Q8S3C0    ), 
D5FAD_PHYPA (A9SIZ6    ), D5FAD_THRSP (Q8S3C1    ), D8FAD_REBSA (A4KDP1    ), 
DAP1_SCHPO  (O13995    ), DAP1_YEAST  (Q12091    ), DES6_CERPU  (Q9LEM9    ), 
FAD5A_DICDI (Q9Y1W0    ), FAD5B_DICDI (O96099    ), FADS1_HUMAN (O60427    ), 
FADS1_MOUSE (Q920L1    ), FADS1_PAPAN (A4UVI1    ), FADS1_RAT   (Q920R3    ), 
FADS2_BOVIN (A4FV48    ), FADS2_DANRE (Q9DEX7    ), FADS2_HUMAN (O95864    ), 
FADS2_MACFA (Q4R749    ), FADS2_MOUSE (Q9Z0R9    ), FADS2_PONAB (Q5REA7    ), 
FADS2_RAT   (Q9Z122    ), FADS3_HUMAN (Q9Y5Q0    ), FADS3_MOUSE (Q9JJE7    ), 
FADS3_RAT   (Q8K1P9    ), FAT3_CAEEL  (Q23221    ), FAT4_CAEEL  (G5EG11    ), 
HERC2_HUMAN (O95714    ), HERC2_MOUSE (Q4U2R1    ), MAPR4_ARATH (Q2HIW2    ), 
MSBP1_ARATH (Q9XFM6    ), MSBP2_ARATH (Q9M2Z4    ), NENF_BOVIN  (Q1JQA5    ), 
NENF_HUMAN  (Q9UMX5    ), NENF_MOUSE  (Q9CQ45    ), NENF_RAT    (Q6IUR5    ), 
NEUFC_CAEBR (Q60YT6    ), NEUFC_CAEEL (Q9XXA7    ), NEUFC_DANRE (A2CES0    ), 
NEUFC_DROME (Q9W376    ), NEUFC_DROPS (Q29HF1    ), NEUFC_HUMAN (Q8WUJ1    ), 
NEUFC_MOUSE (Q5SSH8    ), NEUFC_RAT   (Q6AY62    ), NEUFC_XENTR (Q28FI8    ), 
PGRC1_BOVIN (Q17QC0    ), PGRC1_CHICK (Q5ZKN2    ), PGRC1_HUMAN (O00264    ), 
PGRC1_MOUSE (O55022    ), PGRC1_PIG   (Q95250    ), PGRC1_PONAB (Q5RED0    ), 
PGRC1_RAT   (P70580    ), PGRC2_HUMAN (O15173    ), PGRC2_MOUSE (Q80UU9    ), 
PGRC2_RAT   (Q5XIU9    ), SBP3_ARATH  (Q9SK39    ), SLD1_ARATH  (Q9ZRP7    ), 
SLD1_BOROF  (Q9FR82    ), SLD1_EUGGR  (Q9SWQ9    ), SLD1_HELAN  (Q43469    ), 
SLD1_KLULA  (Q6CMK7    ), SLD1_KLULC  (Q8NKG8    ), SLD1_LACK1  (Q8NKG9    ), 
SLD2_ARATH  (Q3EBF7    ), SUOX_MACFA  (Q60HD0    )
» more

UniProtKB/Swiss-Prot
'Partial' sequences
2 sequences

NIA2_MAIZE  (P39871    ), NIA_LOTTE   (P39882    )

		
UniProtKB/Swiss-Prot
False positive sequences
21 sequences

CDK14_CALJA (B0VXE8    ), CDK14_DASNO (C0RW22    ), CDK14_HUMAN (O94921    ), 
CDK14_MOUSE (O35495    ), CDK14_PLEMO (B0VXL7    ), CDK14_RABIT (B6A7Q3    ), 
CDK14_XENLA (Q6DJM7    ), CDK14_XENTR (A4IIW7    ), CO057_MOUSE (Q8BS39    ), 
CO057_RAT   (Q561K4    ), HYAL3_PIG   (Q6RHW2    ), LAR1B_HUMAN (Q659C4    ), 
LARP1_HUMAN (Q6PKG0    ), LARP1_MOUSE (Q6ZQ58    ), MATK_WEDBI  (Q6JVN2    ), 
MSRAB_HELPJ (Q9ZMK8    ), PPCEL_XENLA (Q32N48    ), SFSA_METS4  (B0ULY8    ), 
VCLY_TEGPF  (P07447    ), VILI_BOVIN  (Q3SZP7    ), VILL_HUMAN  (O15195    )
» more

PDB
[Detailed view]
61 PDB

1AQA; 1AW3; 1AWP; 1AXX; 1B5A; 1B5B; 1B5M; 1BFX; 1BLV; 1CYO; 1DO9; 1EHB; 1ES1; 1EUE; 1F03; 1F04; 1FCB; 1HKO; 1I5U; 1I87; 1I8C; 1IB7; 1ICC; 1IET; 1IEU; 1J0Q; 1JEX; 1KBI; 1LCO; 1LDC; 1LJ0; 1LQX; 1LR6; 1LTD; 1M20; 1M2I; 1M2M; 1MJ4; 1MNY; 1NX7; 1SH4; 1SOX; 1U9M; 1U9U; 2AXX; 2I89; 2I96; 2IBJ; 2M33; 2OZ0; 3KS0; 3LF5; 3MUS; 3NER; 3OZZ; 3X32; 3X33; 3X34; 3X35; 4HIL; 4HIN
» more

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