Entry: PS00191

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General information about the entry

Entry name [info] CYTOCHROME_B5_1
Accession [info] PS00191
Entry type [info] PATTERN
Date [info] APR-1990 (CREATED); DEC-2004 (DATA UPDATE); SEP-2014 (INFO UPDATE).
PROSITE Doc. [info] PDOC00170

Name and characterization of the entry

Description [info] Cytochrome b5 family, heme-binding domain signature.
Pattern [info]
[FY]-[LIVMK]-{I}-{Q}-H-P-[GA]-G.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2014_10 which contains 546'790 sequence entries.


Total number of hits 115 in 115 different sequences
Number of true positive hits 94 in 94 different sequences
Number of 'unknown' hits
Number of false positive hits 21 in 21 different sequences
Number of false negative sequences 65
Number of 'partial' sequences 2
Precision (true positives / (true positives + false positives)) 81.74 %
Recall (true positives / (true positives + false negatives)) 59.12 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info] 1
Site [info] heme_iron at position 5
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
94 sequences

ACO1_AJECA  (Q12618), ACO1_YEAST  (P21147), CYB2_HANAN  (P09437), 
CYB2_YEAST  (P00175), CYB52_SCHPO (Q9USM6), CYB5A_ARATH (Q42342), 
CYB5B_ARATH (O48845), CYB5B_HUMAN (O43169), CYB5B_MOUSE (Q9CQX2), 
CYB5B_PONAB (Q5RDJ5), CYB5B_RAT   (P04166), CYB5C_ARATH (Q9ZNV4), 
CYB5D_ARATH (Q9ZWT2), CYB5L_MIMIV (Q5UR80), CYB5L_NEUCR (Q8X0J4), 
CYB5R_DROME (P19967), CYB5R_DROVI (P50266), CYB5S_TOBAC (P49099), 
CYB5_ALOSE  (P00168), CYB5_BOROF  (O04354), CYB5_BOVIN  (P00171), 
CYB5_BRAOB  (P40934), CYB5_CANTR  (Q874I5), CYB5_CHICK  (P00174), 
CYB5_CUSRE  (P49097), CYB5_DROME  (Q9V4N3), CYB5_HORSE  (P00170), 
CYB5_HUMAN  (P00167), CYB5_MORAP  (Q9Y706), CYB5_MOUSE  (P56395), 
CYB5_MUSDO  (P49096), CYB5_NEUCR  (Q9P5L0), CYB5_ORYSJ  (P49100), 
CYB5_PIG    (P00172), CYB5_RABIT  (P00169), CYB5_RAT    (P00173), 
CYB5_RHIST  (Q9HFV1), CYB5_TOBAC  (P49098), CYB5_YEAST  (P40312), 
CYBL_RHOGR  (P32953), FA2H_HUMAN  (Q7L5A8), FA2H_MACFA  (Q4R4P4), 
FA2H_MOUSE  (Q5MPP0), FA2H_RAT    (Q2LAM0), FAD5C_DICDI (Q1ZXQ5), 
FAD5_MORAP  (O74212), IRC21_YEAST (Q04772), NB5R4_BOVIN (Q32LH7), 
NB5R4_DANRE (Q502I6), NB5R4_HUMAN (Q7L1T6), NB5R4_MOUSE (Q3TDX8), 
NB5R4_RAT   (Q68EJ0), NB5R4_XENTR (Q28CZ9), NIA1_ARATH  (P11832), 
NIA1_BRANA  (P39867), NIA1_HORVU  (P27967), NIA1_MAIZE  (P17571), 
NIA1_ORYSJ  (P16081), NIA1_PHAVU  (P39865), NIA1_SOYBN  (P54233), 
NIA1_TOBAC  (P11605), NIA2_ARATH  (P11035), NIA2_BRANA  (P39868), 
NIA2_HORVU  (P27969), NIA2_PHAVU  (P39866), NIA2_SOYBN  (P39870), 
NIA2_TOBAC  (P08509), NIA3_MAIZE  (P49102), NIA7_HORVU  (P27968), 
NIA_ASPNG   (P36858), NIA_BEABA   (P43100), NIA_BETPN   (P27783), 
NIA_CHLVU   (Q01170), NIA_CICIN   (P43101), NIA_CUCMA   (P17569), 
NIA_EMENI   (P22945), NIA_FUSOX   (P39863), NIA_LEPMC   (P36842), 
NIA_LOTJA   (P39869), NIA_NEUCR   (P08619), NIA_PETHY   (P36859), 
NIA_PHYIN   (P39864), NIA_PICAN   (P49050), NIA_SOLLC   (P17570), 
NIA_SPIOL   (P23312), NIA_USTMA   (Q05531), NIA_VOLCA   (P36841), 
SCS7_YEAST  (Q03529), SUOX_CHICK  (P07850), SUOX_DROME  (Q9VWP4), 
SUOX_HUMAN  (P51687), SUOX_MOUSE  (Q8R086), SUOX_RAT    (Q07116), 
YDAA_SCHPO  (Q10352)
» More

UniProtKB/Swiss-Prot
False negative sequences
65 sequences

ACO1_SCHPO  (O94523), CB5D1_DANRE (Q567I9), CB5D1_HUMAN (Q6P9G0), 
CB5D1_MOUSE (Q5NCY3), CB5D1_PONAB (Q5R4Q5), CB5D1_XENLA (Q5PPR6), 
CB5D1_XENTR (Q0IHR1), CYB5_ECTSH  (P82291), DAP1_SCHPO  (O13995), 
DAP1_YEAST  (Q12091), FAD5A_DICDI (Q9Y1W0), FAD5B_DICDI (O96099), 
FADS1_HUMAN (O60427), FADS1_MOUSE (Q920L1), FADS1_PAPAN (A4UVI1), 
FADS1_RAT   (Q920R3), FADS2_BOVIN (A4FV48), FADS2_DANRE (Q9DEX7), 
FADS2_HUMAN (O95864), FADS2_MACFA (Q4R749), FADS2_MOUSE (Q9Z0R9), 
FADS2_PONAB (Q5REA7), FADS2_RAT   (Q9Z122), FADS3_HUMAN (Q9Y5Q0), 
FADS3_MOUSE (Q9JJE7), FADS3_RAT   (Q8K1P9), FAT3_CAEEL  (Q23221), 
FAT4_CAEEL  (G5EG11), HERC2_HUMAN (O95714), HERC2_MOUSE (Q4U2R1), 
MSBP1_ARATH (Q9XFM6), MSBP2_ARATH (Q9M2Z4), NENF_BOVIN  (Q1JQA5), 
NENF_HUMAN  (Q9UMX5), NENF_MOUSE  (Q9CQ45), NENF_RAT    (Q6IUR5), 
NEUFC_CAEBR (Q60YT6), NEUFC_CAEEL (Q9XXA7), NEUFC_DANRE (A2CES0), 
NEUFC_DROME (Q9W376), NEUFC_DROPS (Q29HF1), NEUFC_HUMAN (Q8WUJ1), 
NEUFC_MOUSE (Q5SSH8), NEUFC_RAT   (Q6AY62), NEUFC_XENTR (Q28FI8), 
PGRC1_BOVIN (Q17QC0), PGRC1_CHICK (Q5ZKN2), PGRC1_HUMAN (O00264), 
PGRC1_MOUSE (O55022), PGRC1_PIG   (Q95250), PGRC1_PONAB (Q5RED0), 
PGRC1_RAT   (P70580), PGRC2_HUMAN (O15173), PGRC2_MOUSE (Q80UU9), 
PGRC2_RAT   (Q5XIU9), SBP3_ARATH  (Q9SK39), SLD1_ARATH  (Q9ZRP7), 
SLD1_BOROF  (Q9FR82), SLD1_EUGGR  (Q9SWQ9), SLD1_HELAN  (Q43469), 
SLD1_KLULA  (Q6CMK7), SLD1_KLULC  (Q8NKG8), SLD1_LACK1  (Q8NKG9), 
SLD2_ARATH  (Q3EBF7), SUOX_MACFA  (Q60HD0)
» More

UniProtKB/Swiss-Prot
'Partial' sequences
2 sequences

NIA2_MAIZE  (P39871), NIA_LOTTE   (P39882)

		
UniProtKB/Swiss-Prot
False positive sequences
21 sequences

CDK14_CALJA (B0VXE8), CDK14_CALMO (B0VXL7), CDK14_DASNO (C0RW22), 
CDK14_HUMAN (O94921), CDK14_MOUSE (O35495), CDK14_RABIT (B6A7Q3), 
CDK14_XENLA (Q6DJM7), CDK14_XENTR (A4IIW7), CO057_MOUSE (Q8BS39), 
CO057_RAT   (Q561K4), HYAL3_PIG   (Q6RHW2), LAR1B_HUMAN (Q659C4), 
LARP1_HUMAN (Q6PKG0), LARP1_MOUSE (Q6ZQ58), MATK_WEDBI  (Q6JVN2), 
MSRAB_HELPJ (Q9ZMK8), PPCEL_XENLA (Q32N48), SFSA_METS4  (B0ULY8), 
VCLY_TEGPF  (P07447), VILI_BOVIN  (Q3SZP7), VILL_HUMAN  (O15195)
» More

PDB
[Detailed view]
57 PDB

1AQA; 1AW3; 1AWP; 1AXX; 1B5A; 1B5B; 1B5M; 1BFX; 1BLV; 1CYO; 1DO9; 1EHB; 1ES1; 1EUE; 1F03; 1F04; 1FCB; 1HKO; 1I5U; 1I87; 1I8C; 1IB7; 1ICC; 1IET; 1IEU; 1J0Q; 1JEX; 1KBI; 1LCO; 1LDC; 1LJ0; 1LQX; 1LR6; 1LTD; 1M20; 1M2I; 1M2M; 1MJ4; 1MNY; 1NX7; 1SH4; 1SOX; 1U9M; 1U9U; 2AXX; 2I89; 2I96; 2IBJ; 2M33; 2OZ0; 3KS0; 3LF5; 3MUS; 3NER; 3OZZ; 4HIL; 4HIN
» More

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