Entry: PS00191

General information about the entry

Entry name [info] CYTOCHROME_B5_1
Accession [info] PS00191
Entry type [info] PATTERN
Date [info] APR-1990 (CREATED); DEC-2004 (DATA UPDATE); JUN-2015 (INFO UPDATE).
PROSITE Doc. [info] PDOC00170

Name and characterization of the entry

Description [info] Cytochrome b5 family, heme-binding domain signature.
Pattern [info]
[FY]-[LIVMK]-{I}-{Q}-H-P-[GA]-G.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2015_08 which contains 320'201 sequence entries.


Total number of hits 118 in 118 different sequences
Number of true positive hits 97 in 97 different sequences
Number of 'unknown' hits 0
Number of false positive hits 21 in 21 different sequences
Number of false negative sequences 66
Number of 'partial' sequences 2
Precision (true positives / (true positives + false positives)) 82.20 %
Recall (true positives / (true positives + false negatives)) 59.51 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info] 1
Site [info] heme_iron at position 5
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
97 sequences

ACO1_AJECA  (Q12618), ACO1_YEAST  (P21147), CYB2_HANAN  (P09437), 
CYB2_YEAST  (P00175), CYB52_SCHPO (Q9USM6), CYB5A_ARATH (Q9FDW8), 
CYB5B_ARATH (O48845), CYB5B_HUMAN (O43169), CYB5B_MOUSE (Q9CQX2), 
CYB5B_PONAB (Q5RDJ5), CYB5B_RAT   (P04166), CYB5C_ARATH (Q9ZNV4), 
CYB5D_ARATH (Q9ZWT2), CYB5E_ARATH (Q42342), CYB5L_MIMIV (Q5UR80), 
CYB5L_NEUCR (Q8X0J4), CYB5R_DROME (P19967), CYB5R_DROVI (P50266), 
CYB5S_TOBAC (P49099), CYB5_ALOSE  (P00168), CYB5_BOROF  (O04354), 
CYB5_BOVIN  (P00171), CYB5_BRAOB  (P40934), CYB5_CANTR  (Q874I5), 
CYB5_CHICK  (P00174), CYB5_CUSRE  (P49097), CYB5_DROME  (Q9V4N3), 
CYB5_HORSE  (P00170), CYB5_HUMAN  (P00167), CYB5_MORAP  (Q9Y706), 
CYB5_MOUSE  (P56395), CYB5_MUSDO  (P49096), CYB5_NEUCR  (Q9P5L0), 
CYB5_ORYSJ  (P49100), CYB5_PIG    (P00172), CYB5_RABIT  (P00169), 
CYB5_RAT    (P00173), CYB5_RHIST  (Q9HFV1), CYB5_TOBAC  (P49098), 
CYB5_YEAST  (P40312), CYBL_RHOGR  (P32953), CYP5F_ARATH (O22704), 
FA2H_HUMAN  (Q7L5A8), FA2H_MACFA  (Q4R4P4), FA2H_MOUSE  (Q5MPP0), 
FA2H_RAT    (Q2LAM0), FAD5C_DICDI (Q1ZXQ5), FAD5_MORAP  (O74212), 
IRC21_YEAST (Q04772), NB5R4_BOVIN (Q32LH7), NB5R4_DANRE (Q502I6), 
NB5R4_HUMAN (Q7L1T6), NB5R4_MOUSE (Q3TDX8), NB5R4_RAT   (Q68EJ0), 
NB5R4_XENTR (Q28CZ9), NIA1_ARATH  (P11832), NIA1_BRANA  (P39867), 
NIA1_HORVU  (P27967), NIA1_MAIZE  (P17571), NIA1_ORYSJ  (P16081), 
NIA1_PHAVU  (P39865), NIA1_SOYBN  (P54233), NIA1_TOBAC  (P11605), 
NIA2_ARATH  (P11035), NIA2_BRANA  (P39868), NIA2_HORVU  (P27969), 
NIA2_PHAVU  (P39866), NIA2_SOYBN  (P39870), NIA2_TOBAC  (P08509), 
NIA3_MAIZE  (P49102), NIA7_HORVU  (P27968), NIA_ASPNG   (P36858), 
NIA_BEABA   (P43100), NIA_BETPN   (P27783), NIA_CHLVU   (Q01170), 
NIA_CICIN   (P43101), NIA_CUCMA   (P17569), NIA_EMENI   (P22945), 
NIA_FUSOX   (P39863), NIA_LEPMC   (P36842), NIA_LOTJA   (P39869), 
NIA_NEUCR   (P08619), NIA_PETHY   (P36859), NIA_PHYIN   (P39864), 
NIA_PICAN   (P49050), NIA_SOLLC   (P17570), NIA_SPIOL   (P23312), 
NIA_USTMA   (Q05531), NIA_VOLCA   (P36841), RLF_ARATH   (Q9LXD1), 
SCS7_YEAST  (Q03529), SUOX_CHICK  (P07850), SUOX_DROME  (Q9VWP4), 
SUOX_HUMAN  (P51687), SUOX_MOUSE  (Q8R086), SUOX_RAT    (Q07116), 
YDAA_SCHPO  (Q10352)
» More

UniProtKB/Swiss-Prot
False negative sequences
66 sequences

ACO1_SCHPO  (O94523), CB5D1_DANRE (Q567I9), CB5D1_HUMAN (Q6P9G0), 
CB5D1_MOUSE (Q5NCY3), CB5D1_PONAB (Q5R4Q5), CB5D1_XENLA (Q5PPR6), 
CB5D1_XENTR (Q0IHR1), CYB5_ECTSH  (P82291), DAP1_SCHPO  (O13995), 
DAP1_YEAST  (Q12091), FAD5A_DICDI (Q9Y1W0), FAD5B_DICDI (O96099), 
FADS1_HUMAN (O60427), FADS1_MOUSE (Q920L1), FADS1_PAPAN (A4UVI1), 
FADS1_RAT   (Q920R3), FADS2_BOVIN (A4FV48), FADS2_DANRE (Q9DEX7), 
FADS2_HUMAN (O95864), FADS2_MACFA (Q4R749), FADS2_MOUSE (Q9Z0R9), 
FADS2_PONAB (Q5REA7), FADS2_RAT   (Q9Z122), FADS3_HUMAN (Q9Y5Q0), 
FADS3_MOUSE (Q9JJE7), FADS3_RAT   (Q8K1P9), FAT3_CAEEL  (Q23221), 
FAT4_CAEEL  (G5EG11), HERC2_HUMAN (O95714), HERC2_MOUSE (Q4U2R1), 
MAPR4_ARATH (Q2HIW2), MSBP1_ARATH (Q9XFM6), MSBP2_ARATH (Q9M2Z4), 
NENF_BOVIN  (Q1JQA5), NENF_HUMAN  (Q9UMX5), NENF_MOUSE  (Q9CQ45), 
NENF_RAT    (Q6IUR5), NEUFC_CAEBR (Q60YT6), NEUFC_CAEEL (Q9XXA7), 
NEUFC_DANRE (A2CES0), NEUFC_DROME (Q9W376), NEUFC_DROPS (Q29HF1), 
NEUFC_HUMAN (Q8WUJ1), NEUFC_MOUSE (Q5SSH8), NEUFC_RAT   (Q6AY62), 
NEUFC_XENTR (Q28FI8), PGRC1_BOVIN (Q17QC0), PGRC1_CHICK (Q5ZKN2), 
PGRC1_HUMAN (O00264), PGRC1_MOUSE (O55022), PGRC1_PIG   (Q95250), 
PGRC1_PONAB (Q5RED0), PGRC1_RAT   (P70580), PGRC2_HUMAN (O15173), 
PGRC2_MOUSE (Q80UU9), PGRC2_RAT   (Q5XIU9), SBP3_ARATH  (Q9SK39), 
SLD1_ARATH  (Q9ZRP7), SLD1_BOROF  (Q9FR82), SLD1_EUGGR  (Q9SWQ9), 
SLD1_HELAN  (Q43469), SLD1_KLULA  (Q6CMK7), SLD1_KLULC  (Q8NKG8), 
SLD1_LACK1  (Q8NKG9), SLD2_ARATH  (Q3EBF7), SUOX_MACFA  (Q60HD0)
» More

UniProtKB/Swiss-Prot
'Partial' sequences
2 sequences

NIA2_MAIZE  (P39871), NIA_LOTTE   (P39882)

		
UniProtKB/Swiss-Prot
False positive sequences
21 sequences

CDK14_CALJA (B0VXE8), CDK14_CALMO (B0VXL7), CDK14_DASNO (C0RW22), 
CDK14_HUMAN (O94921), CDK14_MOUSE (O35495), CDK14_RABIT (B6A7Q3), 
CDK14_XENLA (Q6DJM7), CDK14_XENTR (A4IIW7), CO057_MOUSE (Q8BS39), 
CO057_RAT   (Q561K4), HYAL3_PIG   (Q6RHW2), LAR1B_HUMAN (Q659C4), 
LARP1_HUMAN (Q6PKG0), LARP1_MOUSE (Q6ZQ58), MATK_WEDBI  (Q6JVN2), 
MSRAB_HELPJ (Q9ZMK8), PPCEL_XENLA (Q32N48), SFSA_METS4  (B0ULY8), 
VCLY_TEGPF  (P07447), VILI_BOVIN  (Q3SZP7), VILL_HUMAN  (O15195)
» More

PDB
[Detailed view]
57 PDB

1AQA; 1AW3; 1AWP; 1AXX; 1B5A; 1B5B; 1B5M; 1BFX; 1BLV; 1CYO; 1DO9; 1EHB; 1ES1; 1EUE; 1F03; 1F04; 1FCB; 1HKO; 1I5U; 1I87; 1I8C; 1IB7; 1ICC; 1IET; 1IEU; 1J0Q; 1JEX; 1KBI; 1LCO; 1LDC; 1LJ0; 1LQX; 1LR6; 1LTD; 1M20; 1M2I; 1M2M; 1MJ4; 1MNY; 1NX7; 1SH4; 1SOX; 1U9M; 1U9U; 2AXX; 2I89; 2I96; 2IBJ; 2M33; 2OZ0; 3KS0; 3LF5; 3MUS; 3NER; 3OZZ; 4HIL; 4HIN
» More

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