PROSITE entry PS00222

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General information about the entry

Entry name [info]	IGFBP_N_1
Accession [info]	PS00222
Entry type [info]	PATTERN
Date [info]	01-APR-1990 CREATED; 01-DEC-2004 DATA UPDATE; 27-MAR-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC00194

Name and characterization of the entry

Description [info]	Insulin-like growth factor-binding protein (IGFBP) N-terminal domain signature.
Pattern [info]	[GP]-C-[GSET]-[CE]-[CA]-x(2)-C-[ALP]-x(6)-C.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_02 which contains 571'282 sequence entries.

Total number of hits	60 in 60 different sequences
Number of true positive hits	60 in 60 different sequences
Number of 'unknown' hits	0
Number of false positive hits	0
Number of false negative sequences	18
Number of 'partial' sequences	1

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	76.92 %

Comments [info]

Taxonomic range [info]	Eukaryotes
Maximum number of repetitions [info]	1
Version [info]	1

Cross-references [info]

UniProtKB/Swiss-Prot True positive sequences	60 sequences CCN1_CHICK (P19336), CCN1_HUMAN (O00622), CCN1_MOUSE (P18406), CCN1_PANTR (A5A6L1), CCN1_RAT(Q9ES72), CCN2_BOVIN (O18739), CCN2_HUMAN (P29279), CCN2_MOUSE (P29268), CCN2_PIG(O19113), CCN2_RAT(Q9R1E9), CCN3_CHICK (P28686), CCN3_COTJA (P42642), CCN3_HUMAN (P48745), CCN3_MOUSE (Q64299), CCN3_RAT(Q9QZQ5), CCN3_XENLA (P51609), CCN4_HUMAN (O95388), CCN4_MOUSE (O54775), CCN4_RAT(Q99PP0), CCN5_HUMAN (O76076), CCN5_MOUSE (Q9Z0G4), CCN5_RAT(Q9JHC6), CCN6_HUMAN (O95389), CCN6_MOUSE (D3Z5L9), IBP1_BOVIN (P24591), IBP1_HUMAN (P08833), IBP1_ICTTR (Q6Q484), IBP1_MOUSE (P47876), IBP1_RAT(P21743), IBP2A_DANRE (Q9PTH3), IBP2B_DANRE (B3F211), IBP2_BOVIN (P13384), IBP2_CHICK (P49705), IBP2_HUMAN (P18065), IBP2_MOUSE (P47877), IBP2_PIG(P24853), IBP2_RAT(P12843), IBP2_SHEEP (Q29400), IBP2_XENLA (Q5XHC5), IBP2_XENTR (A4IIA2), IBP3_BOVIN (P20959), IBP3_HUMAN (P17936), IBP3_MOUSE (P47878), IBP3_PIG(P16611), IBP3_RAT(P15473), IBP4_BOVIN (Q05716), IBP4_HUMAN (P22692), IBP4_MOUSE (P47879), IBP4_PIG(P24854), IBP4_RAT(P21744), IBP4_SHEEP (Q28893), IBP5_BOVIN (Q05717), IBP5_HUMAN (P24593), IBP5_MOUSE (Q07079), IBP5_PIG(Q28985), IBP5_RAT(P24594), IBP5_XENLA (Q90WV8), IBP6_MOUSE (P47880), PLSLP_LOTGI (B3A0Q9), PLS_HALLA (P82595) » more Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits: [Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format] Retrieve the sequence logo from the alignment
UniProtKB/Swiss-Prot False negative sequences	18 sequences HTR1B_DANRE (A9JRB3), HTRA1_BOVIN (F1N152), HTRA1_XENLA (A6YFB5), HTRA1_XENTR (A4IHA1), HTRA3_HUMAN (P83110), HTRA3_MOUSE (Q9D236), HTRA3_RAT (D3ZA76), HTRA4_BOVIN (E1BJW1), HTRA4_MOUSE (A2RT60), HTRA4_RAT (D3ZKF5), IBP6_BOVIN (Q05718), IBP6_HUMAN (P24592), IBP6_RAT(P35572), IGFBP_CUPSA (G4V4G1), SIBD1_CUPSA (G4V4F9), SIBD2_CUPSA (G4V4G0), VP302_LYCMC (P0CJ14), VP59_LYCMC (P0CJ12) » more
UniProtKB/Swiss-Prot 'Partial' sequences	1 sequence IBP2_ONCTS (P83628)
PDB [Detailed view]	6 PDB 1WQJ; 2DSP; 2DSQ; 2DSR; 7UFG; 7WRQ