Entry: PS00258

General information about the entry

Entry name [info] CALCITONIN
Accession [info] PS00258
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED; 01-JUN-1992 DATA UPDATE; 05-JUL-2017 INFO UPDATE.
PROSITE Doc. [info] PDOC00231

Name and characterization of the entry

Description [info] Calcitonin / CGRP / IAPP family signature.
Pattern [info] 
C-[SAGDN]-[STN]-x(0,1)-[SA]-T-C-[VMA]-x(3)-[LYF]-x(3)-[LYF].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2017_07 which contains 555'100 sequence entries.


Total number of hits 42 in 42 different sequences
Number of true positive hits 42 in 42 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 6
Number of 'partial' sequences 4
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 87.50 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Site [info] disulfide at position 1
Site [info] disulfide at position 7
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 42 sequences 

CALC1_ONCKE (P01263    ), CALC2_ONCGO (P69165    ), CALC2_ONCKE (P69067    ), 

CALC2_ONCNE (P69068    ), CALC3_ONCKI (P01265    ), CALCA_CANLF (Q9MYV1    ), 
CALCA_CHICK (P10286    ), CALCA_HUMAN (P06881    ), CALCA_MOUSE (Q99JA0    ), 
CALCA_PIG   (P30880    ), CALCA_RAT   (P01256    ), CALCA_SHEEP (P30881    ), 
CALCB_HORSE (Q9N0T3    ), CALCB_HUMAN (P10092    ), CALCB_MOUSE (Q99MP3    ), 
CALCB_RAT   (P10093    ), CALCR_PELRI (P31888    ), CALCR_PHYBI (P81564    ), 
CALC_ANGJA  (P01262    ), CALC_BOVIN  (P01260    ), CALC_CANLF  (P41547    ), 
CALC_CHICK  (P07660    ), CALC_HORSE  (Q9N0V5    ), CALC_HUMAN  (P01258    ), 
CALC_MOUSE  (P70160    ), CALC_PIG    (P01259    ), CALC_RAT    (P01257    ), 
CALC_SHEEP  (P01261    ), CRSP1_BOVIN (Q75V95    ), CRSP1_CANLF (Q75V94    ), 
CRSP1_CAPHI (B3IWF7    ), CRSP1_PIG   (Q862B1    ), CRSP1_SHEEP (B3IWF9    ), 
IAPP_CANLF  (P17716    ), IAPP_CAVPO  (P12966    ), IAPP_CRIGR  (P19890    ), 
IAPP_FELCA  (P12967    ), IAPP_HUMAN  (P10997    ), IAPP_MESAU  (P23442    ), 
IAPP_MOUSE  (P12968    ), IAPP_OCTDE  (P22889    ), IAPP_RAT    (P12969    )
» more

UniProtKB/Swiss-Prot
False negative sequences		 6 sequences 

CALC_LITCT  (P0C234    ), CRSP2_CANLF (Q75V93    ), CRSP2_CAPHI (B3IWF8    ), 

CRSP2_PIG   (Q766Y7    ), CRSP3_PIG   (Q766Y6    ), IAPP_BOVIN  (Q28207    )
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 4 sequences 

IAPP_PIG    (Q29119    ), IAPP_RABIT  (Q07334    ), IAPP_SAGOE  (Q28934    ), 

IAPP_SHEEP  (Q28605    )
» more

PDB
[Detailed view]		 11 PDB

1BKU; 1BYV; 1BZB; 2GLG; 2GLH; 2JXZ; 2KB8; 2KJ7; 2L86; 3G7V; 3G7W

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