Entry: PS00258

General information about the entry
Entry name CALCITONIN
Accession number PS00258
Entry type PATTERN
Date APR-1990 (CREATED); JUN-1992 (DATA UPDATE); MAR-2013 (INFO UPDATE).
PROSITE Documentation PDOC00231
Name and characterization of the entry
DescriptionCalcitonin / CGRP / IAPP family signature.
Pattern C-[SAGDN]-[STN]-x(0,1)-[SA]-T-C-[VMA]-x(3)-[LYF]-x(3)-[LYF].
Numerical results
  • UniProtKB/Swiss-Prot release number: 2013_05, total number of sequence entries in that release: 540052.
  • Total number of hits in UniProtKB/Swiss-Prot: 42 hits in 42 different sequences
  • Number of hits on proteins that are known to belong to the set under consideration: 42 hits in 42 different sequences
  • Number of hits on proteins that could potentially belong to the set under consideration: 0 hits in 0 different sequences
  • Number of false hits (on unrelated proteins): 0 hits in 0 different sequences
  • Number of known missed hits: 6
  • Number of partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences: 4
  • Precision (true hits / (true hits + false positives)): 100.00 %
  • Recall (true hits / (true hits + false negatives)): 87.50 %
Comments
  • Taxonomic range: Eukaryotes
  • Maximum known number of repetitions of the pattern in a single protein: 1
  • `Interesting' site in the pattern: 1,disulfide
  • `Interesting' site in the pattern: 7,disulfide
  • VERSION: 1
Cross-references
UniProtKB/Swiss-Prot True positive hits:
CALC1_ONCKE (P01263), CALC2_ONCGO (P69165), CALC2_ONCKE (P69067), 
CALC2_ONCNE (P69068), CALC3_ONCKI (P01265), CALCA_CANFA (Q9MYV1), 
CALCA_CHICK (P10286), CALCA_HUMAN (P06881), CALCA_MOUSE (Q99JA0), 
CALCA_PIG   (P30880), CALCA_RAT   (P01256), CALCA_SHEEP (P30881), 
CALCB_HORSE (Q9N0T3), CALCB_HUMAN (P10092), CALCB_MOUSE (Q99MP3), 
CALCB_RAT   (P10093), CALCR_PELRI (P31888), CALCR_PHYBI (P81564), 
CALC_ANGJA  (P01262), CALC_BOVIN  (P01260), CALC_CANFA  (P41547), 
CALC_CHICK  (P07660), CALC_HORSE  (Q9N0V5), CALC_HUMAN  (P01258), 
CALC_MOUSE  (P70160), CALC_PIG    (P01259), CALC_RAT    (P01257), 
CALC_SHEEP  (P01261), CRSP1_BOVIN (Q75V95), CRSP1_CANFA (Q75V94), 
CRSP1_CAPHI (B3IWF7), CRSP1_PIG   (Q862B1), CRSP1_SHEEP (B3IWF9), 
IAPP_CANFA  (P17716), IAPP_CAVPO  (P12966), IAPP_CRIGR  (P19890), 
IAPP_FELCA  (P12967), IAPP_HUMAN  (P10997), IAPP_MESAU  (P23442), 
IAPP_MOUSE  (P12968), IAPP_OCTDE  (P22889), IAPP_RAT    (P12969)
False negative hits (sequences which belong to the set under consideration, but which have not been picked up by the pattern or profile):
CALC_LITCT  (P0C234), CRSP2_CANFA (Q75V93), CRSP2_CAPHI (B3IWF8), 
CRSP2_PIG   (Q766Y7), CRSP3_PIG   (Q766Y6), IAPP_BOVIN  (Q28207)
`Potential' hits (partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences):
IAPP_PIG    (Q29119), IAPP_RABIT  (Q07334), IAPP_SAGOE  (Q28934), 
IAPP_SHEEP  (Q28605)
Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:

[Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format]

Retrieve the sequence logo from the alignment

PDB
[Detailed view]		 1BKU; 1BYV; 1BZB; 1LS7; 2GLG; 2GLH; 2JXZ; 2KB8; 2KJ7; 2L86; 3G7V; 3G7W;

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