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PROSITE entry PS00261


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General information about the entry

Entry name [info] GLYCO_HORMONE_BETA_1
Accession [info] PS00261
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-NOV-1995 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00234

Name and characterization of the entry

Description [info] Glycoprotein hormones beta chain signature 1.
Pattern [info]
C-[STAGM]-G-[HFYL]-C-x-[ST].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_06 which contains 572'619 sequence entries.


Total number of hits 133 in 129 different sequences
Number of true positive hits 105 in 105 different sequences
Number of 'unknown' hits 0
Number of false positive hits 28 in 24 different sequences
Number of false negative sequences 7
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 78.95 %
Recall (true positives / (true positives + false negatives)) 93.75 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 2
Site [info] disulfide at position 1
Site [info] disulfide at position 5
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
105 sequences

CGB1_HUMAN  (A6NKQ9), CGB2_HUMAN  (Q6NT52), CGB3_HUMAN  (P0DN86), 
CGB7_HUMAN  (P0DN87), CGHB_AOTNA  (Q3HRV3), CGHB_CALJA  (P51500), 
CGHB_PAPAN  (P07434), CGHB_SAIBB  (Q3S2X5), FSHB_AILME  (Q8WN19), 
FSHB_AOTNA  (Q3HRV4), FSHB_AQUCT  (Q9PS36), FSHB_BOVIN  (P04837), 
FSHB_BUBBU  (Q6SV86), FSHB_CAPHI  (Q8HY83), FSHB_CAVPO  (Q9JK69), 
FSHB_CERNI  (Q8HY84), FSHB_GORGO  (A1BN60), FSHB_HORSE  (P01226), 
FSHB_HUMAN  (P01225), FSHB_MACFA  (Q6EV79), FSHB_MASCO  (Q6SI68), 
FSHB_MERUN  (Q6U830), FSHB_MONDO  (Q95J82), FSHB_MOUSE  (Q60687), 
FSHB_PANTA  (Q9BDJ0), FSHB_PANTR  (Q2PUH2), FSHB_PHOSU  (Q9QYB0), 
FSHB_PIG(P01228), FSHB_PONPY  (A1BN61), FSHB_RABIT  (Q6IY73), 
FSHB_SAIBB  (Q3YC02), FSHB_SHEEP  (P01227), FSHB_STRCA  (P80663), 
FSHB_TRIVU  (O46430), GTHB1_ANGJA (Q9YGK3), GTHB1_CARAU (Q98848), 
GTHB1_CORAU (P48250), GTHB1_CYPCA (O13050), GTHB1_ICTPU (Q9DG81), 
GTHB1_ONCKE (P10257), GTHB1_ONCMA (P48252), GTHB2_ACALA (Q90225), 
GTHB2_ANGAN (P27767), GTHB2_CARAU (Q98849), GTHB2_CLAGA (P53543), 
GTHB2_CLUPA (Q9YGH2), GTHB2_CORAU (P48251), GTHB2_CTEID (P30984), 
GTHB2_CYPCA (P01235), GTHB2_FUNHE (P30972), GTHB2_HYPMO (P37038), 
GTHB2_ICTPU (Q9DG80), GTHB2_MORSA (Q91121), GTHB2_ONCKE (P10256), 
GTHB2_ONCMA (P48253), GTHB2_ONCTS (P07732), GTHB2_THUOB (P37206), 
GTHB2_TRITC (Q9PW98), GTHB_MURCI  (P12837), LSHB_AILFU  (Q8HZR9), 
LSHB_AILME  (Q8WN18), LSHB_AQUCT  (P80071), LSHB_BALAC  (P33088), 
LSHB_BOVIN  (P04651), LSHB_CANLF  (P18842), LSHB_CERSI  (O77835), 
LSHB_COTJA  (P45657), LSHB_EQUAS  (P19794), LSHB_EQUQB  (O46641), 
LSHB_FELCA  (O77805), LSHB_GORGO  (Q2Q1P1), LSHB_HORSE  (P08751), 
LSHB_HUMAN  (P01229), LSHB_MACFA  (Q6EV78), LSHB_MELGA  (P45646), 
LSHB_MONDO  (Q95J85), LSHB_MOUSE  (O09108), LSHB_OSPRU  (O46483), 
LSHB_PANTA  (Q9BDI9), LSHB_PANTR  (Q2Q1P2), LSHB_PHOSU  (Q9QYA9), 
LSHB_PHYMC  (P25330), LSHB_PIG(P01232), LSHB_PONPY  (Q2Q1P0), 
LSHB_RABIT  (Q6IY74), LSHB_RAT(P01230), LSHB_SHEEP  (P01231), 
LSHB_STRCA  (P80664), LSHB_TRIVU  (O46482), TSHB_ANGAN  (Q08127), 
TSHB_ANGJA  (Q7ZZV4), TSHB_BOVIN  (P01223), TSHB_CANLF  (P54828), 
TSHB_CHICK  (O57340), TSHB_FELCA  (Q52R90), TSHB_HORSE  (Q28376), 
TSHB_HUMAN  (P01222), TSHB_LAMGL  (P79357), TSHB_MONDO  (Q95J88), 
TSHB_MOUSE  (P12656), TSHB_ONCMY  (P37240), TSHB_PHOSU  (Q62590), 
TSHB_PIG(P01224), TSHB_RAT(P04652), TSHB_SALSA  (O73824)
» more

UniProtKB/Swiss-Prot
False negative sequences
7 sequences

FSHB_RAT(P18427), GPHB5_HUMAN (Q86YW7), GPHB5_MOUSE (Q812B2), 
GTHB1_FUNHE (P30971), GTHB1_MORSA (Q91120), GTHB1_THUOB (P37205), 
GTHB1_TRITC (Q9PW99)
» more

UniProtKB/Swiss-Prot
False positive sequences
24 sequences

005L_IIV3   (Q197F5), BRAT1_DANRE (Q1RLU1), CDNF_MOUSE  (Q8CC36), 
CE034_MOUSE (Q3UJC8), CNT3B_HUMAN (Q96NU0), CNTP2_HUMAN (Q9UHC6), 
CNTP2_MOUSE (Q9CPW0), CNTP2_PONAB (Q5RD64), CNTP3_HUMAN (Q9BZ76), 
CP089_HUMAN (Q6UX73), CTP5B_MOUSE (Q0V8T8), DPOL_HBVGO  (Q9YPV8), 
FABH_CUTAC  (P0DW99), ORC3_ORYSJ  (Q0IY07), PID4_CAEEL  (O44749), 
SSPO_BOVIN  (P98167), SSPO_HUMAN  (A2VEC9), SSPO_MOUSE  (Q8CG65), 
SSPO_RAT(Q700K0), TBWKD_DROME (Q9VGL8), THIM_GRABC  (Q0BVF4), 
VF337_IIV6  (Q91FI7), ZMYM4_HUMAN (Q5VZL5), ZMYM4_MOUSE (A2A791)
» more

PDB
[Detailed view]
15 PDB

1FL7; 1HCN; 1HRP; 1QFW; 1XWD; 4AY9; 4MQW; 6P57; 7FIG; 7FIH; 7FII; 7T9I; 7UTZ; 7XW5; 8I2G
» more