Entry: PS00280

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General information about the entry

Entry name [info] BPTI_KUNITZ_1
Accession [info] PS00280
Entry type [info] PATTERN
Date [info] APR-1990 (CREATED); APR-2006 (DATA UPDATE); JUL-2014 (INFO UPDATE).
PROSITE Doc. [info] PDOC00252

Name and characterization of the entry

Description [info] Pancreatic trypsin inhibitor (Kunitz) family signature.
Pattern [info]
F-x(2)-{I}-G-C-x(6)-[FY]-x(5)-C.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2014_08 which contains 546'238 sequence entries.


Total number of hits 337 in 275 different sequences
Number of true positive hits 332 in 270 different sequences
Number of 'unknown' hits
Number of false positive hits 5 in 5 different sequences
Number of false negative sequences 58
Number of 'partial' sequences 18
Precision (true positives / (true positives + false positives)) 98.52 %
Recall (true positives / (true positives + false negatives)) 85.13 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 11
Site [info] disulfide at position 5
Site [info] disulfide at position 9
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
270 sequences

A4_CAVPO    (Q60495), A4_HUMAN    (P05067), A4_MACFA    (P53601), 
A4_MACMU    (P29216), A4_MOUSE    (P12023), A4_PANTR    (Q5IS80), 
A4_PIG      (P79307), A4_RAT      (P08592), A4_SAISC    (Q95241), 
A4_TAKRU    (O93279), AMBP_BOVIN  (P00978), AMBP_HUMAN  (P02760), 
AMBP_MERUN  (Q62577), AMBP_MESAU  (Q60559), AMBP_MOUSE  (Q07456), 
AMBP_PIG    (P04366), AMBP_PLEPL  (P36992), AMBP_RAT    (Q64240), 
ANIS1_ANISI (Q7Z1K3), APKT1_ANTEL (P86862), APLP2_HUMAN (Q06481), 
APLP2_RAT   (P15943), BMTI6_RHIMP (P83606), BMTIA_RHIMP (P83609), 
BOOG2_RHIMP (Q8WPI3), BOOH2_RHIMP (Q8WPI2), BPT1_BOVIN  (P00974), 
BPT2_BOVIN  (P04815), CO6A3_CHICK (P15989), CO6A3_HUMAN (P12111), 
CO7A1_HUMAN (Q02388), CO7A1_MOUSE (Q63870), COSA1_HUMAN (Q2UY09), 
COSA1_MOUSE (Q2UY11), CRPTI_RHIMP (P81162), CSTI_BOMMO  (P81902), 
ELAC_MACEU  (O62845), ELAC_TRIVU  (Q29143), EPPI_HUMAN  (O95925), 
EPPI_MACMU  (Q9BDL1), EPPI_MOUSE  (Q9DA01), EPPI_RAT    (D4A2Z2), 
HTIB_MANSE  (P26227), IATR_CAPHI  (P62756), IATR_HORSE  (P04365), 
IATR_SHEEP  (P62757), IBPC_BOVIN  (P00976), IBPI_TACTR  (P16044), 
IBPS_BOVIN  (P00975), IBP_CARCR   (P00993), IMAP_DROFU  (P11424), 
ISC1_BOMMO  (P10831), ISC2_BOMMO  (P10832), ISC3_BOMMO  (P07481), 
ISIK_HELPO  (P00994), ISPI2_GALME (P81906), IVBI3_HOPST (B5L5R6), 
IVBI4_NOTSC (B5L5R4), IVBI4_PSEPO (B5L5R0), IVBI5_PSEPO (B5L5R1), 
IVBI_AUSSU  (B5L5M7), IVBS5_OXYSC (B5L5Q3), KCP1_PINMA  (P86959), 
KCP1_PINMG  (H2A0M2), KCP2_PINMG  (H2A0N1), KCP3_PINMA  (P86964), 
KCP3_PINMG  (H2A0N5), KCP4_PINMG  (H2A0N9), KCP5_PINMG  (H2A0P0), 
KCP_HALAI   (P86733), MCPI_MELCP  (P82968), PCPI_SABMA  (P84875), 
PPN1_CAEEL  (O76840), PPN_DROME   (Q868Z9), PPN_HUMAN   (O95428), 
PPN_MOUSE   (Q9EPX2), SBPI_SARBU  (P26228), SPIT1_HUMAN (O43278), 
SPIT1_MOUSE (Q9R097), SPIT2_HUMAN (O43291), SPIT2_MOUSE (Q9WU03), 
SPIT3_HUMAN (P49223), SPIT4_MOUSE (Q9D263), TFPI1_HUMAN (P10646), 
TFPI1_MACMU (Q28864), TFPI1_MOUSE (O54819), TFPI1_RABIT (P19761), 
TFPI1_RAT   (Q02445), TFPI2_BOVIN (Q7YRQ8), TFPI2_HUMAN (P48307), 
TFPI2_MOUSE (O35536), TKDP1_BOVIN (Q28201), TKDP1_SHEEP (Q29428), 
UPTI_PIG    (Q29100), VKBH2_BUNCA (Q8AY45), VKT11_HADGE (P0C8W3), 
VKT11_HAPSC (B2ZBB6), VKT12_DENAN (P0DMJ6), VKT12_MESMA (P0DJ47), 
VKT16_DRYCN (F8J2F4), VKT17_HAPHA (P0DJ66), VKT18_DRYCN (F8J2F6), 
VKT19_ANOSM (Q589G4), VKT1A_HAPSC (P68425), VKT1L_BUNMU (B4ESA2), 
VKT1_ACTEQ  (P0DMJ2), VKT1_ANESU  (Q9TWG0), VKT1_ANTAF  (P81547), 
VKT1_ARAVE  (Q8T3S7), VKT1_AUSSU  (B5KL38), VKT1_BITGA  (Q6T6T5), 
VKT1_DABRR  (Q2ES50), VKT1_DEMVE  (A6MFL1), VKT1_HETCR  (B2G331), 
VKT1_HOPST  (B5KF94), VKT1_NOTSC  (Q6ITB3), VKT1_OXYMI  (Q6ITB5), 
VKT1_OXYSC  (Q6ITB7), VKT1_PHIOL  (A7X3V7), VKT1_PSERS  (E7FL11), 
VKT1_PSETT  (Q90WA1), VKT1_RHING  (B5KF95), VKT1_STOHE  (P31713), 
VKT1_TELDH  (A7X3V4), VKT1_TRILK  (W4VSH9), VKT1_TROCA  (Q6ITB0), 
VKT1_VIPAA  (P00991), VKT1_WALAE  (C1IC50), VKT27_HAPSC (P0DJ82), 
VKT28_DRYCN (F8J2F3), VKT2L_BUNMU (B4ESA3), VKT2_ANESU  (Q9TWF9), 
VKT2_ANTAF  (P81548), VKT2_AUSSU  (B5KL39), VKT2_BITGA  (Q6T6S5), 
VKT2_DABSI  (P00990), VKT2_DEMVE  (A6MFL2), VKT2_HEMHA  (P00985), 
VKT2_HETCR  (C0HJF4), VKT2_HOPST  (B5L5R7), VKT2_NAJNI  (P00986), 
VKT2_NOTSC  (Q6ITB2), VKT2_OXYMI  (Q6ITB4), VKT2_OXYSC  (Q6ITB6), 
VKT2_PIMHY  (Q8T0W4), VKT2_PSEAU  (Q6ITC0), VKT2_PSEPO  (B5G6G6), 
VKT2_PSERS  (E7FL12), VKT2_PSETT  (Q90WA0), VKT2_RHING  (B5KF96), 
VKT2_STOHE  (P81129), VKT2_TROCA  (B5KL33), VKT2_WALAE  (C1IC52), 
VKT31_MESMA (P0DJ50), VKT39_HAPSC (P0DMJ1), VKT3L_BUNMU (B4ESA4), 
VKT3_ANESU  (Q9TWF8), VKT3_AUSSU  (B5KL40), VKT3_BITGA  (Q6T269), 
VKT3_DABRR  (Q2ES48), VKT3_DEMVE  (A6MFL3), VKT3_HETCR  (C0HJF3), 
VKT3_NOTSC  (B5KL32), VKT3_OXYMI  (B5KL27), VKT3_OXYSC  (B5KL29), 
VKT3_PSEAU  (Q6ITB9), VKT3_PSEPO  (B5KL31), VKT3_PSERS  (E7FL13), 
VKT3_PSETT  (Q90W99), VKT3_RHING  (B5KL34), VKT3_STIHA  (B1B5I8), 
VKT3_VIPAA  (P00992), VKT3_WALAE  (C1IC51), VKT4_AUSSU  (B5KL41), 
VKT4_DABRR  (Q2ES47), VKT4_DEMVE  (A6MFL4), VKT4_HAPSC  (P0DJ76), 
VKT4_OXYMI  (B5KL28), VKT4_OXYSC  (B5KL30), VKT4_PSEAU  (Q6ITB8), 
VKT4_PSETT  (Q90W98), VKT4_RHING  (B5KL35), VKT4_WALAE  (C1IC53), 
VKT52_ANESU (P10280), VKT5_DABRR  (Q2ES46), VKT5_DEMVE  (A6MGX9), 
VKT5_HAPSC  (P0DJ77), VKT5_OXYMI  (B5L5Q6), VKT5_PSEAU  (B5L5Q8), 
VKT5_PSETT  (Q90W97), VKT5_RHING  (B5KL36), VKT6_PSETT  (Q90W96), 
VKT6_RHING  (B5KL37), VKT7_DEMVE  (A6MGY1), VKT7_PSETT  (B5L5Q1), 
VKT87_DRYCN (F8J2F5), VKT9_BUNFA  (P25660), VKTA_BUNCA  (Q8AY43), 
VKTB1_DABSI (A8Y7P1), VKTB2_DABSI (A8Y7P2), VKTB3_DABSI (A8Y7P3), 
VKTB4_DABSI (A8Y7P4), VKTB5_DABSI (A8Y7P5), VKTB6_DABSI (A8Y7P6), 
VKTB7_DABSI (A8Y7P0), VKTB_BUNCA  (Q8AY42), VKTC1_DABSI (A8Y7N4), 
VKTC2_DABSI (A8Y7N5), VKTC3_DABSI (A8Y7N6), VKTC4_DABSI (A8Y7N7), 
VKTC5_DABSI (A8Y7N8), VKTC6_DABSI (A8Y7N9), VKTCI_NAJNA (P19859), 
VKTCI_OPHHA (P82966), VKTCT_OPHHA (B6RLX2), VKTC_BUNCA  (Q8AY41), 
VKTE_DENPO  (P00984), VKTH1_BUNFA (B2KTG2), VKTH1_BUNMU (P00987), 
VKTH1_DENPO (P00979), VKTH1_PSEAU (Q6ITC1), VKTH2_BUNFA (B2KTG3), 
VKTH2_BUNMU (P00989), VKTH3_BUNCA (Q75S50), VKTH3_BUNMU (Q9W728), 
VKTH4_BUNCA (Q75S49), VKTH4_BUNMU (Q1RPT0), VKTH5_BUNMU (Q1RPS9), 
VKTH6_BUNMU (Q1RPS8), VKTH7_BUNCA (Q8AY44), VKTH7_BUNMU (Q0PL65), 
VKTHA_DENAN (P00980), VKTHB_BUNCA (Q8AY46), VKTHB_BUNFL (Q7T2Q6), 
VKTHB_DENPO (P00983), VKTHC_DENAN (P81658), VKTHD_DENAN (P00982), 
VKTHE_DENAN (Q7LZE3), VKTHK_DENPO (P00981), VKTI1_ANTFU (P0DMJ3), 
VKTI3_ANTFU (P0DMJ4), VKTK1_DABRR (H6VC05), VKTK2_DABRR (H6VC06), 
VKTRE_DENAN (Q7LZS8), VKTTI_NAJNA (P20229), VKT_AUSLA   (B2BS84), 
VKT_BOMIG   (G3LH89), VKT_BOMTE   (D8KY58), VKT_BUNFA   (B2KTG1), 
VKT_ERIMA   (P24541), VKT_HETCR   (P0DMJ5), VKT_MACLN   (I2G9B4), 
VKT_NAJAT   (Q5ZPJ7), VKT_OXYSC   (B7S4N9), VKT_PSEPO   (Q6ITB1), 
VKT_SISCA   (A5X2X1), VKT_VIPNI   (E5AJX3), VKT_VIPRE   (P0DKL8), 
WFC6A_MOUSE (Q3UW55), WFC6B_MOUSE (F6ULY1), WFDC8_HUMAN (Q8IUA0), 
WFDC8_MOUSE (Q4KUS1), WFKN1_HUMAN (Q96NZ8), WFKN1_MOUSE (Q8R0S6), 
WFKN1_RAT   (P0C5J5), WFKN2_BOVIN (Q08E66), WFKN2_HUMAN (Q8TEU8), 
WFKN2_MOUSE (Q7TQN3), WFKN_DANRE  (Q6NUX0), YN81_CAEEL  (Q03610)
» More

UniProtKB/Swiss-Prot
False negative sequences
58 sequences

A4_TETFL    (O73683), ORNT_ORNMO  (P56409), SPIT4_HUMAN (Q6UDR6), 
TAP_ORNMO   (P17726), VKT13_HAPSC (P0DJ79), VKT1A_CONCL (D2Y488), 
VKT1B_CONCL (D2Y489), VKT1C_CONCL (D2Y490), VKT1D_CONCL (D2Y491), 
VKT21_LYCMC (P0DJ46), VKT22_HAPSC (P0DJ80), VKT22_LYCMC (P0DJ45), 
VKT23_LYCMC (P0DJ48), VKT24_HAPSC (P0DJ81), VKT24_MESMA (P0DJ49), 
VKT2_DABRR  (Q2ES49), VKT2_HAPHA  (D2Y2F3), VKT2_HAPSC  (P0DJ75), 
VKT31_HAPHA (P0DJ64), VKT33_HAPSC (B2ZBB8), VKT34_HAPHA (P0DJ67), 
VKT35_HAPHA (P0DJ71), VKT40_HAPSC (P0DJ84), VKT45_HAPHA (P0DJ68), 
VKT45_HAPSC (P0DJ85), VKT4_HAPHA  (D2Y2F5), VKT4_HETCR  (P16344), 
VKT52_HAPHA (P0DJ69), VKT53_HAPHA (P0DJ70), VKT68_HAPHA (P0DJ72), 
VKT6_HAPSC  (P0DJ78), VKT74_HAPHA (P0DJ73), VKT76_HAPHA (P0DJ74), 
VKT7_HAPHA  (P0DJ65), VKTA1_HAPHA (D2Y2C2), VKTA_MICTN  (G9I929), 
VKTB1_CONBU (P0CY85), VKTC1_HAPHA (D2Y2F4), VKTE1_HAPHA (D2Y2F6), 
VKTF1_HAPHA (D2Y2F7), VKTG1_HAPHA (D2Y2F8), VKTG6_HAPSC (B2ZBB9), 
VKTG9_HAPSC (B2ZBC0), VKTH1_HAPHA (D2Y2F9), VKTI1_HAPHA (D2Y2G0), 
VKTJ1_HAPHA (D2Y2G1), VKTK1_HAPHA (D2Y2G2), VKTL1_HAPHA (D2Y2Q1), 
VKTM1_HAPHA (D2Y2Q2), VKTN1_HAPHA (D2Y2Q5), VKTO1_HAPHA (D2Y2Q6), 
VKTP1_HAPHA (D2Y2Q7), VKTQ1_HAPHA (D2Y2Q8), VKTR1_HAPHA (D2Y2Q9), 
VKTS1_CONST (P0C1X2), VKT_VESBI   (C0LNR2), WFDC6_HUMAN (Q9BQY6), 
YL15_CAEEL  (Q11101)
» More

UniProtKB/Swiss-Prot
'Partial' sequences
18 sequences

BMTI2_RHIMP (P83603), BMTI3_RHIMP (P83604), BMTI4_RHIMP (P83605), 
BMTID_RHIMP (P83607), HTIA_MANSE  (P26226), TIQ2_RHISA  (P84554), 
TIQ7_RHISA  (P84555), TIS5_RHISA  (P84556), VKT10_DABSI (P85041), 
VKT25_HAPHA (P0CH75), VKTC8_DABSI (P85039), VKTC9_DABSI (P85040), 
VKTG1_MICPY (P0CAR0), VKTH1_BUNCA (P84471), VKTH2_BUNCA (P84473), 
VKTH8_BUNCA (P84470), VKT_MICAT   (P0DM47), VKT_OXYMI   (P0DJ63)
» More

UniProtKB/Swiss-Prot
False positive sequences
5 sequences

LRIT2_HUMAN (A6NDA9), SSPO_HUMAN  (A2VEC9), TGB3_BNYVS  (Q65676), 
TNFA_TUPTA  (Q539C2), WAKLN_ARATH (Q0WNY5)
» More

PDB
[Detailed view]
129 PDB

1AAP; 1ADZ; 1B0C; 1BF0; 1BHC; 1BIK; 1BPI; 1BPT; 1BRB; 1BRC; 1BTH; 1BTI; 1BUN; 1BZ5; 1BZX; 1CA0; 1CBW; 1CO7; 1D0D; 1DEM; 1DEN; 1DTK; 1DTX; 1EAW; 1EJM; 1F5R; 1F7Z; 1FAK; 1FY8; 1G6X; 1IRH; 1JC6; 1K6U; 1KNT; 1KTH; 1KUN; 1LD5; 1MTN; 1NAG; 1OA5; 1OA6; 1P2I; 1P2J; 1P2K; 1P2M; 1P2N; 1P2O; 1P2Q; 1PIT; 1QLQ; 1SHP; 1T7C; 1T8L; 1T8M; 1T8N; 1T8O; 1TAW; 1TFX; 1TPA; 1UUA; 1UUB; 1YC0; 1YKT; 1ZJD; 1ZR0; 2DDI; 2DDJ; 2FI4; 2FTL; 2FTM; 2HEX; 2IJO; 2JOT; 2KAI; 2KNT; 2M99; 2ODY; 2PTC; 2R9P; 2RA3; 2TGP; 2TPI; 3BTD; 3BTE; 3BTF; 3BTG; 3BTH; 3BTK; 3BTM; 3BTQ; 3BTT; 3BTW; 3BYB; 3D65; 3FP6; 3FP7; 3FP8; 3GYM; 3L33; 3LDI; 3LDJ; 3LDM; 3M7Q; 3OFW; 3OTJ; 3P92; 3P95; 3T62; 3TGI; 3TGJ; 3TGK; 3TPI; 3U1J; 3UIR; 3UOU; 4BD9; 4BNR; 4BQD; 4DG4; 4DTG; 4ISL; 4ISN; 4ISO; 4PTI; 4TPI; 5PTI; 6PTI; 8PTI; 9PTI
» More

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