Entry: PS00280

General information about the entry

Entry name [info] BPTI_KUNITZ_1
Accession [info] PS00280
Entry type [info] PATTERN
Date [info] APR-1990 (CREATED); APR-2006 (DATA UPDATE); JUN-2015 (INFO UPDATE).
PROSITE Doc. [info] PDOC00252

Name and characterization of the entry

Description [info] Pancreatic trypsin inhibitor (Kunitz) family signature.
Pattern [info]
F-x(2)-{I}-G-C-x(6)-[FY]-x(5)-C.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2015_08 which contains 320'201 sequence entries.


Total number of hits 341 in 279 different sequences
Number of true positive hits 335 in 273 different sequences
Number of 'unknown' hits 0
Number of false positive hits 6 in 6 different sequences
Number of false negative sequences 58
Number of 'partial' sequences 20
Precision (true positives / (true positives + false positives)) 98.24 %
Recall (true positives / (true positives + false negatives)) 85.24 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 11
Site [info] disulfide at position 5
Site [info] disulfide at position 9
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
273 sequences

A4_CAVPO    (Q60495), A4_HUMAN    (P05067), A4_MACFA    (P53601), 
A4_MACMU    (P29216), A4_MOUSE    (P12023), A4_PANTR    (Q5IS80), 
A4_PIG      (P79307), A4_RAT      (P08592), A4_SAISC    (Q95241), 
A4_TAKRU    (O93279), AMBP_BOVIN  (P00978), AMBP_HUMAN  (P02760), 
AMBP_MERUN  (Q62577), AMBP_MESAU  (Q60559), AMBP_MOUSE  (Q07456), 
AMBP_PIG    (P04366), AMBP_PLEPL  (P36992), AMBP_RAT    (Q64240), 
ANIS1_ANISI (Q7Z1K3), APKT1_ANTEL (P86862), APLP2_HUMAN (Q06481), 
APLP2_RAT   (P15943), BMTI6_RHIMP (P83606), BMTIA_RHIMP (P83609), 
BOOG2_RHIMP (Q8WPI3), BOOH2_RHIMP (Q8WPI2), BPT1_BOVIN  (P00974), 
BPT2_BOVIN  (P04815), CO6A3_CHICK (P15989), CO6A3_HUMAN (P12111), 
CO7A1_HUMAN (Q02388), CO7A1_MOUSE (Q63870), COSA1_HUMAN (Q2UY09), 
COSA1_MOUSE (Q2UY11), CRPTI_RHIMP (P81162), CSTI_BOMMO  (P81902), 
ELAC_MACEU  (O62845), ELAC_TRIVU  (Q29143), EPPI_HUMAN  (O95925), 
EPPI_MACMU  (Q9BDL1), EPPI_MOUSE  (Q9DA01), EPPI_RAT    (D4A2Z2), 
HTIB_MANSE  (P26227), IATR_CAPHI  (P62756), IATR_HORSE  (P04365), 
IATR_SHEEP  (P62757), IBPC_BOVIN  (P00976), IBPI_TACTR  (P16044), 
IBPS_BOVIN  (P00975), IBP_CARCR   (P00993), IMAP_DROFU  (P11424), 
ISC1_BOMMO  (P10831), ISC2_BOMMO  (P10832), ISC3_BOMMO  (P07481), 
ISIK_HELPO  (P00994), ISPI2_GALME (P81906), IVBI3_HOPST (B5L5R6), 
IVBI4_NOTSC (B5L5R4), IVBI4_PSEPO (B5L5R0), IVBI5_PSEPO (B5L5R1), 
IVBI_AUSSU  (B5L5M7), IVBS5_OXYSC (B5L5Q3), KCP1_PINMA  (P86959), 
KCP1_PINMG  (H2A0M2), KCP2_PINMG  (H2A0N1), KCP3_PINMA  (P86964), 
KCP3_PINMG  (H2A0N5), KCP4_PINMG  (H2A0N9), KCP5_PINMG  (H2A0P0), 
KCP_HALAI   (P86733), MCPI_MELCP  (P82968), PCPI_SABMA  (P84875), 
PPN1_CAEEL  (O76840), PPN_DROME   (Q868Z9), PPN_HUMAN   (O95428), 
PPN_MOUSE   (Q9EPX2), SBPI_NEOBL  (P26228), SPIT1_HUMAN (O43278), 
SPIT1_MOUSE (Q9R097), SPIT2_HUMAN (O43291), SPIT2_MOUSE (Q9WU03), 
SPIT3_HUMAN (P49223), SPIT4_MOUSE (Q9D263), TFPI1_HUMAN (P10646), 
TFPI1_MACMU (Q28864), TFPI1_MOUSE (O54819), TFPI1_RABIT (P19761), 
TFPI1_RAT   (Q02445), TFPI2_BOVIN (Q7YRQ8), TFPI2_HUMAN (P48307), 
TFPI2_MOUSE (O35536), TKDP1_BOVIN (Q28201), TKDP1_SHEEP (Q29428), 
UPTI_PIG    (Q29100), VKBH2_BUNCA (Q8AY45), VKT11_HADGE (P0C8W3), 
VKT11_HAPSC (B2ZBB6), VKT12_DENAN (P0DMJ6), VKT12_MESMA (P0DJ47), 
VKT16_DRYCN (F8J2F4), VKT17_HAPHA (P0DJ66), VKT18_DRYCN (F8J2F6), 
VKT19_ANOSM (Q589G4), VKT1A_HAPSC (P68425), VKT1L_BUNMU (B4ESA2), 
VKT1_ACTEQ  (P0DMJ2), VKT1_ANESU  (Q9TWG0), VKT1_ANTAF  (P81547), 
VKT1_ARAVE  (Q8T3S7), VKT1_AUSSU  (B5KL38), VKT1_BITGA  (Q6T6T5), 
VKT1_CRYNI  (B5KF95), VKT1_DABRR  (Q2ES50), VKT1_DEMVE  (A6MFL1), 
VKT1_HETCR  (B2G331), VKT1_HOPST  (B5KF94), VKT1_NOTSC  (Q6ITB3), 
VKT1_OXYMI  (Q6ITB5), VKT1_OXYSC  (Q6ITB7), VKT1_PHIOL  (A7X3V7), 
VKT1_PSERS  (E7FL11), VKT1_PSETT  (Q90WA1), VKT1_STIHL  (P31713), 
VKT1_TELDH  (A7X3V4), VKT1_TRILK  (W4VSH9), VKT1_TROCA  (Q6ITB0), 
VKT1_VIPAA  (P00991), VKT1_WALAE  (C1IC50), VKT27_HAPSC (P0DJ82), 
VKT28_DRYCN (F8J2F3), VKT2L_BUNMU (B4ESA3), VKT2_ANESU  (Q9TWF9), 
VKT2_ANTAF  (P81548), VKT2_AUSSU  (B5KL39), VKT2_BITGA  (Q6T6S5), 
VKT2_CRYNI  (B5KF96), VKT2_DABSI  (P00990), VKT2_DEMVE  (A6MFL2), 
VKT2_HEMHA  (P00985), VKT2_HETCR  (C0HJF4), VKT2_HOPST  (B5L5R7), 
VKT2_NAJNI  (P00986), VKT2_NOTSC  (Q6ITB2), VKT2_OXYMI  (Q6ITB4), 
VKT2_OXYSC  (Q6ITB6), VKT2_PIMHY  (Q8T0W4), VKT2_PSEAU  (Q6ITC0), 
VKT2_PSEPO  (B5G6G6), VKT2_PSERS  (E7FL12), VKT2_PSETT  (Q90WA0), 
VKT2_STIHL  (P81129), VKT2_TROCA  (B5KL33), VKT2_WALAE  (C1IC52), 
VKT31_MESMA (P0DJ50), VKT39_HAPSC (P0DMJ1), VKT3A_ACTEQ (P0DMW6), 
VKT3B_ACTEQ (P0DMW7), VKT3L_BUNMU (B4ESA4), VKT3_ANESU  (Q9TWF8), 
VKT3_ANTAF  (P0DMX0), VKT3_AUSSU  (B5KL40), VKT3_BITGA  (Q6T269), 
VKT3_CRYNI  (B5KL34), VKT3_DABRR  (Q2ES48), VKT3_DEMVE  (A6MFL3), 
VKT3_HETCR  (C0HJF3), VKT3_NOTSC  (B5KL32), VKT3_OXYMI  (B5KL27), 
VKT3_OXYSC  (B5KL29), VKT3_PSEAU  (Q6ITB9), VKT3_PSEPO  (B5KL31), 
VKT3_PSERS  (E7FL13), VKT3_PSETT  (Q90W99), VKT3_STIHA  (B1B5I8), 
VKT3_VIPAA  (P00992), VKT3_WALAE  (C1IC51), VKT4_AUSSU  (B5KL41), 
VKT4_CRYNI  (B5KL35), VKT4_DABRR  (Q2ES47), VKT4_DEMVE  (A6MFL4), 
VKT4_HAPSC  (P0DJ76), VKT4_OXYMI  (B5KL28), VKT4_OXYSC  (B5KL30), 
VKT4_PSEAU  (Q6ITB8), VKT4_PSETT  (Q90W98), VKT4_WALAE  (C1IC53), 
VKT52_ANESU (P10280), VKT5_CRYNI  (B5KL36), VKT5_DABRR  (Q2ES46), 
VKT5_DEMVE  (A6MGX9), VKT5_HAPSC  (P0DJ77), VKT5_OXYMI  (B5L5Q6), 
VKT5_PSEAU  (B5L5Q8), VKT5_PSETT  (Q90W97), VKT6_CRYNI  (B5KL37), 
VKT6_PSETT  (Q90W96), VKT7_DEMVE  (A6MGY1), VKT7_PSETT  (B5L5Q1), 
VKT87_DRYCN (F8J2F5), VKT9_BUNFA  (P25660), VKTA_BUNCA  (Q8AY43), 
VKTB1_DABSI (A8Y7P1), VKTB2_DABSI (A8Y7P2), VKTB3_DABSI (A8Y7P3), 
VKTB4_DABSI (A8Y7P4), VKTB5_DABSI (A8Y7P5), VKTB6_DABSI (A8Y7P6), 
VKTB7_DABSI (A8Y7P0), VKTB_BUNCA  (Q8AY42), VKTC1_DABSI (A8Y7N4), 
VKTC2_DABSI (A8Y7N5), VKTC3_DABSI (A8Y7N6), VKTC4_DABSI (A8Y7N7), 
VKTC5_DABSI (A8Y7N8), VKTC6_DABSI (A8Y7N9), VKTCI_NAJNA (P19859), 
VKTCI_OPHHA (P82966), VKTCT_OPHHA (B6RLX2), VKTC_BUNCA  (Q8AY41), 
VKTE_DENPO  (P00984), VKTH1_BUNFA (B2KTG2), VKTH1_BUNMU (P00987), 
VKTH1_DENPO (P00979), VKTH1_PSEAU (Q6ITC1), VKTH2_BUNFA (B2KTG3), 
VKTH2_BUNMU (P00989), VKTH3_BUNCA (Q75S50), VKTH3_BUNMU (Q9W728), 
VKTH4_BUNCA (Q75S49), VKTH4_BUNMU (Q1RPT0), VKTH5_BUNMU (Q1RPS9), 
VKTH6_BUNMU (Q1RPS8), VKTH7_BUNCA (Q8AY44), VKTH7_BUNMU (Q0PL65), 
VKTHA_DENAN (P00980), VKTHB_BUNCA (Q8AY46), VKTHB_BUNFL (Q7T2Q6), 
VKTHB_DENPO (P00983), VKTHC_DENAN (P81658), VKTHD_DENAN (P00982), 
VKTHE_DENAN (Q7LZE3), VKTHK_DENPO (P00981), VKTI1_ANTFU (P0DMJ3), 
VKTI3_ANTFU (P0DMJ4), VKTK1_DABRR (H6VC05), VKTK2_DABRR (H6VC06), 
VKTRE_DENAN (Q7LZS8), VKTTI_NAJNA (P20229), VKT_AUSLA   (B2BS84), 
VKT_BOMIG   (G3LH89), VKT_BOMTE   (D8KY58), VKT_BUNFA   (B2KTG1), 
VKT_ERIMA   (P24541), VKT_HETCR   (P0DMJ5), VKT_MACLN   (I2G9B4), 
VKT_NAJAT   (Q5ZPJ7), VKT_OXYSC   (B7S4N9), VKT_PSEPO   (Q6ITB1), 
VKT_SISCA   (A5X2X1), VKT_VIPNI   (E5AJX3), VKT_VIPRE   (P0DKL8), 
WFC6A_MOUSE (Q3UW55), WFC6B_MOUSE (F6ULY1), WFDC8_HUMAN (Q8IUA0), 
WFDC8_MOUSE (Q4KUS1), WFKN1_HUMAN (Q96NZ8), WFKN1_MOUSE (Q8R0S6), 
WFKN1_RAT   (P0C5J5), WFKN2_BOVIN (Q08E66), WFKN2_HUMAN (Q8TEU8), 
WFKN2_MOUSE (Q7TQN3), WFKN_DANRE  (Q6NUX0), YN81_CAEEL  (Q03610)
» More

UniProtKB/Swiss-Prot
False negative sequences
58 sequences

A4_TETFL    (O73683), ORNT_ORNMO  (P56409), SPIT4_HUMAN (Q6UDR6), 
TAP_ORNMO   (P17726), VKT13_HAPSC (P0DJ79), VKT1A_CONCL (D2Y488), 
VKT1B_CONCL (D2Y489), VKT1C_CONCL (D2Y490), VKT1D_CONCL (D2Y491), 
VKT21_LYCMC (P0DJ46), VKT22_HAPSC (P0DJ80), VKT22_LYCMC (P0DJ45), 
VKT23_LYCMC (P0DJ48), VKT24_HAPSC (P0DJ81), VKT24_MESMA (P0DJ49), 
VKT2_DABRR  (Q2ES49), VKT2_HAPHA  (D2Y2F3), VKT2_HAPSC  (P0DJ75), 
VKT31_HAPHA (P0DJ64), VKT33_HAPSC (B2ZBB8), VKT34_HAPHA (P0DJ67), 
VKT35_HAPHA (P0DJ71), VKT40_HAPSC (P0DJ84), VKT45_HAPHA (P0DJ68), 
VKT45_HAPSC (P0DJ85), VKT4_HAPHA  (D2Y2F5), VKT4_HETCR  (P16344), 
VKT52_HAPHA (P0DJ69), VKT53_HAPHA (P0DJ70), VKT68_HAPHA (P0DJ72), 
VKT6_HAPSC  (P0DJ78), VKT74_HAPHA (P0DJ73), VKT76_HAPHA (P0DJ74), 
VKT7_HAPHA  (P0DJ65), VKTA1_HAPHA (D2Y2C2), VKTA_MICTN  (G9I929), 
VKTB1_CONBU (P0CY85), VKTC1_HAPHA (D2Y2F4), VKTE1_HAPHA (D2Y2F6), 
VKTF1_HAPHA (D2Y2F7), VKTG1_HAPHA (D2Y2F8), VKTG6_HAPSC (B2ZBB9), 
VKTG9_HAPSC (B2ZBC0), VKTH1_HAPHA (D2Y2F9), VKTI1_HAPHA (D2Y2G0), 
VKTJ1_HAPHA (D2Y2G1), VKTK1_HAPHA (D2Y2G2), VKTL1_HAPHA (D2Y2Q1), 
VKTM1_HAPHA (D2Y2Q2), VKTN1_HAPHA (D2Y2Q5), VKTO1_HAPHA (D2Y2Q6), 
VKTP1_HAPHA (D2Y2Q7), VKTQ1_HAPHA (D2Y2Q8), VKTR1_HAPHA (D2Y2Q9), 
VKTS1_CONST (P0C1X2), VKT_VESBI   (C0LNR2), WFDC6_HUMAN (Q9BQY6), 
YL15_CAEEL  (Q11101)
» More

UniProtKB/Swiss-Prot
'Partial' sequences
20 sequences

BMTI2_RHIMP (P83603), BMTI3_RHIMP (P83604), BMTI4_RHIMP (P83605), 
BMTID_RHIMP (P83607), HTIA_MANSE  (P26226), TIQ2_RHISA  (P84554), 
TIQ7_RHISA  (P84555), TIS5_RHISA  (P84556), VKT10_DABSI (P85041), 
VKT25_HAPHA (P0CH75), VKT33_ACTEQ (P0DMW8), VKT34_ACTEQ (P0DMW9), 
VKTC8_DABSI (P85039), VKTC9_DABSI (P85040), VKTG1_MICPY (P0CAR0), 
VKTH1_BUNCA (P84471), VKTH2_BUNCA (P84473), VKTH8_BUNCA (P84470), 
VKT_MICAT   (P0DM47), VKT_OXYMI   (P0DJ63)
» More

UniProtKB/Swiss-Prot
False positive sequences
6 sequences

AB41G_ORYSJ (Q8GU83), LRIT2_HUMAN (A6NDA9), SSPO_HUMAN  (A2VEC9), 
TGB3_BNYVS  (Q65676), TNFA_TUPTA  (Q539C2), WAKLN_ARATH (Q0WNY5)
» More

PDB
[Detailed view]
131 PDB

1AAP; 1ADZ; 1B0C; 1BF0; 1BHC; 1BIK; 1BPI; 1BPT; 1BRB; 1BRC; 1BTH; 1BTI; 1BUN; 1BZ5; 1BZX; 1CA0; 1CBW; 1CO7; 1D0D; 1DEM; 1DEN; 1DTK; 1DTX; 1EAW; 1EJM; 1F5R; 1F7Z; 1FAK; 1FY8; 1G6X; 1IRH; 1JC6; 1K6U; 1KNT; 1KTH; 1KUN; 1LD5; 1MTN; 1NAG; 1OA5; 1OA6; 1P2I; 1P2J; 1P2K; 1P2M; 1P2N; 1P2O; 1P2Q; 1PIT; 1QLQ; 1SHP; 1T7C; 1T8L; 1T8M; 1T8N; 1T8O; 1TAW; 1TFX; 1TPA; 1UUA; 1UUB; 1YC0; 1YKT; 1ZJD; 1ZR0; 2DDI; 2DDJ; 2FI4; 2FTL; 2FTM; 2HEX; 2IJO; 2JOT; 2KAI; 2KNT; 2M99; 2ODY; 2PTC; 2R9P; 2RA3; 2TGP; 2TPI; 3BTD; 3BTE; 3BTF; 3BTG; 3BTH; 3BTK; 3BTM; 3BTQ; 3BTT; 3BTW; 3BYB; 3D65; 3FP6; 3FP7; 3FP8; 3GYM; 3L33; 3LDI; 3LDJ; 3LDM; 3M7Q; 3OFW; 3OTJ; 3P92; 3P95; 3T62; 3TGI; 3TGJ; 3TGK; 3TPI; 3U1J; 3UIR; 3UOU; 4BD9; 4BNR; 4BQD; 4DG4; 4DTG; 4ISL; 4ISN; 4ISO; 4PTI; 4TPI; 4U30; 4U32; 5PTI; 6PTI; 8PTI; 9PTI
» More

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