Entry: PS00353

General information about the entry
Entry name HMG_BOX_1
Accession number PS00353
Entry type PATTERN
Date NOV-1990 (CREATED); DEC-2004 (DATA UPDATE); MAR-2013 (INFO UPDATE).
PROSITE Documentation PDOC00305
Name and characterization of the entry
DescriptionHMG box A DNA-binding domain signature.
Pattern [FI]-S-[KR]-K-C-x-[EK]-R-W-K-T-[MV].
Numerical results
  • UniProtKB/Swiss-Prot release number: 2013_05, total number of sequence entries in that release: 540052.
  • Total number of hits in UniProtKB/Swiss-Prot: 26 hits in 26 different sequences
  • Number of hits on proteins that are known to belong to the set under consideration: 26 hits in 26 different sequences
  • Number of hits on proteins that could potentially belong to the set under consideration: 0 hits in 0 different sequences
  • Number of false hits (on unrelated proteins): 0 hits in 0 different sequences
  • Number of known missed hits: 29
  • Number of partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences: 0
  • Precision (true hits / (true hits + false positives)): 100.00 %
  • Recall (true hits / (true hits + false negatives)): 47.27 %
Comments
  • Taxonomic range: Eukaryotes, Eukaryotic viruses
  • Maximum known number of repetitions of the pattern in a single protein: 1
  • VERSION: 1
Cross-references
UniProtKB/Swiss-Prot True positive hits:
HMG2_DROME  (Q24537), HMG3M_HUMAN (P0C6E5), HMGB1_BOVIN (P10103), 
HMGB1_CALJA (B0CM99), HMGB1_CALMO (B1MTB0), HMGB1_CANFA (Q6YKA4), 
HMGB1_CHICK (P36194), HMGB1_CRIGR (P07156), HMGB1_HORSE (Q08IE6), 
HMGB1_HUMAN (P09429), HMGB1_MACFA (Q4R844), HMGB1_MOUSE (P63158), 
HMGB1_PAPAN (A9RA84), HMGB1_PIG   (P12682), HMGB1_RAT   (P63159), 
HMGB2_BOVIN (P40673), HMGB2_CHICK (P26584), HMGB2_HUMAN (P26583), 
HMGB2_MOUSE (P30681), HMGB2_PIG   (P17741), HMGB2_RAT   (P52925), 
HMGB3_BOVIN (Q32L31), HMGB3_CHICK (P40618), HMGB3_HUMAN (O15347), 
HMGB3_MOUSE (O54879), HMGT_ONCMY  (P07746)
False negative hits (sequences which belong to the set under consideration, but which have not been picked up by the pattern or profile):
HGB1A_HUMAN (B2RPK0), HM20A_CHICK (Q5ZKF4), HM20A_HUMAN (Q9NP66), 
HM20A_MOUSE (Q9DC33), HM20A_XENLA (Q6AZF8), HM20A_XENTR (Q6DIJ5), 
HM20B_BOVIN (Q32L68), HM20B_HUMAN (Q9P0W2), HM20B_MOUSE (Q9Z104), 
HMGB4_BOVIN (Q32L34), HMGB4_HUMAN (Q8WW32), HMGB4_MOUSE (Q6P8W9), 
HMO1_YEAST  (Q03973), MATA2_CANAL (Q71U11), MATA2_KLULA (Q9HG13), 
MATA2_YARLL (O93958), MATB_NEUCS  (P36981), MATD_NEUCR  (Q10116), 
NHP10_YEAST (Q03435), SMCE1_HUMAN (Q969G3), SMCE1_MOUSE (O54941), 
SMCE1_RAT   (Q56A18), SOX21_MOUSE (Q811W0), TOX3_HUMAN  (O15405), 
TOX3_MOUSE  (Q80W03), TOX3_RAT    (B7SBD2), TOX_HUMAN   (O94900), 
TOX_MOUSE   (Q66JW3), VF401_IIV3  (Q196Z2)
Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:

[Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format]

Retrieve the sequence logo from the alignment

PDB
[Detailed view]
1AAB; 1CKT; 1J3X; 2EQZ; 2LY4; 2YRQ;

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