Entry: PS00460

General information about the entry

Entry name [info] GLUTATHIONE_PEROXID_1
Accession [info] PS00460
Entry type [info] PATTERN
Date [info] MAY-1991 (CREATED); JAN-2008 (DATA UPDATE); JUN-2015 (INFO UPDATE).
PROSITE Doc. [info] PDOC00396

Name and characterization of the entry

Description [info] Glutathione peroxidases active site.
Pattern [info]
[GNDRC]-[RKHNQFYCS]-x-[LIVMFCS]-[LIVMF](2)-x-N-[VT]-x-[STCA]-x-[CU]-
[GA]-x-[TA].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2015_08 which contains 320'201 sequence entries.


Total number of hits 97 in 97 different sequences
Number of true positive hits 97 in 97 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 15
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 86.61 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info] 1
Site [info] active_site at position 12
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
97 sequences

BSAA_BACHD  (Q9Z9N7), BSAA_BACSU  (P52035), BTUE_ECOLI  (P06610), 
GPO_LACLA   (Q9CFV1), GPO_LACLM   (O32770), GPWA_PSEWI  (O08368), 
GPX1_ARATH  (P52032), GPX1_BOVIN  (P00435), GPX1_CAEEL  (O02621), 
GPX1_CALJA  (Q0EF99), GPX1_CHLRE  (P83564), GPX1_HELAN  (O23970), 
GPX1_HUMAN  (P07203), GPX1_HYLLA  (Q4AEI2), GPX1_MACFU  (Q865R2), 
GPX1_MOUSE  (P11352), GPX1_PANTR  (Q0EFA0), GPX1_PEA    (O24296), 
GPX1_PIG    (Q8MJ14), GPX1_PONPY  (Q4AEI3), GPX1_RABIT  (P11909), 
GPX1_RAT    (P04041), GPX1_SAPAP  (Q4AEI1), GPX1_SCHMA  (Q00277), 
GPX1_SCHPO  (O59858), GPX1_SYNY3  (P74250), GPX1_YEAST  (P36014), 
GPX2_ARATH  (O04922), GPX2_CAEEL  (O62327), GPX2_CALJA  (Q0EF98), 
GPX2_HUMAN  (P18283), GPX2_HYLLA  (Q4AEH9), GPX2_MACFU  (Q4AEH8), 
GPX2_MOUSE  (Q9JHC0), GPX2_PONPY  (Q4AEI0), GPX2_RAT    (P83645), 
GPX2_SAPAP  (Q4AEH7), GPX2_SYNY3  (P73824), GPX2_YEAST  (P38143), 
GPX3_ARATH  (O22850), GPX3_BOVIN  (P37141), GPX3_CAEEL  (Q95003), 
GPX3_HUMAN  (P22352), GPX3_HYLLA  (Q4AEH5), GPX3_MACFU  (Q4AEH4), 
GPX3_MOUSE  (P46412), GPX3_PONPY  (Q5RFG3), GPX3_RAT    (P23764), 
GPX3_SAPAP  (Q4AEH3), GPX3_YEAST  (P40581), GPX41_MOUSE (O70325), 
GPX41_RAT   (P36970), GPX42_MOUSE (Q91XR9), GPX42_RAT   (Q91XR8), 
GPX4_ARATH  (Q8L910), GPX4_BOVIN  (Q9N2J2), GPX4_CALJA  (Q32QL6), 
GPX4_CITSI  (Q06652), GPX4_GOSHI  (O49069), GPX4_HELAN  (O23968), 
GPX4_HUMAN  (P36969), GPX4_HYLLA  (Q4AEH1), GPX4_MACFU  (Q4AEH0), 
GPX4_MESCR  (Q9LEF0), GPX4_NICSY  (P30708), GPX4_PIG    (P36968), 
GPX4_PONPY  (Q4AEH2), GPX4_SAPAP  (Q4AEG9), GPX4_SOLLC  (O24031), 
GPX4_SPIOL  (O23814), GPX4_TOBAC  (Q9FXS3), GPX5_ARATH  (Q9LYB4), 
GPX5_CANFA  (O46607), GPX5_HUMAN  (O75715), GPX5_MACFA  (P28714), 
GPX5_MOUSE  (P21765), GPX5_PIG    (O18994), GPX5_RAT    (P30710), 
GPX6_ARATH  (O48646), GPX6_HUMAN  (P59796), GPX6_MOUSE  (Q91WR8), 
GPX6_RAT    (Q64625), GPX7_ARATH  (Q9SZ54), GPX7_BOVIN  (A6QLY2), 
GPX7_HUMAN  (Q96SL4), GPX7_MOUSE  (Q99LJ6), GPX8_ARATH  (Q8LBU2), 
GPXA_NEIMA  (P0A0T4), GPXA_NEIMB  (P0A0T5), GPXA_NEIMC  (P0C2T0), 
GPXA_NEIMF  (A1KV41), GPXC_BRUMA  (P67877), GPXC_BRUPA  (P67878), 
GPXC_DIRIM  (P52033), GPXC_WUCBA  (P35666), GPX_MCV1    (Q98234), 
GPX_PROCL   (G9JJU2)
» More

UniProtKB/Swiss-Prot
False negative sequences
15 sequences

BSAA_STAAC  (Q5HGC7), BSAA_STAAM  (P64290), BSAA_STAAN  (P99097), 
BSAA_STAAR  (Q6GHD0), BSAA_STAAS  (Q6G9Q8), BSAA_STAAW  (P64291), 
BSAA_STAEQ  (Q5HKZ3), BSAA_STAES  (Q8CSR9), GPX8A_XENLA (Q6IRC8), 
GPX8B_XENLA (Q5U583), GPX8_BOVIN  (Q2NL01), GPX8_DANRE  (Q7ZV14), 
GPX8_HUMAN  (Q8TED1), GPX8_MOUSE  (Q9D7B7), GPX8_TETNG  (Q4RSM6)
» More

UniProtKB/Swiss-Prot
'Partial' sequences
1 sequence

GPX4_PINPS  (P81087)

		
PDB
[Detailed view]
5 PDB

2HE3; 2I3Y; 2OBI; 2P31; 3CMI

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