Entry: PS00460

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General information about the entry

Entry name [info] GLUTATHIONE_PEROXID_1
Accession [info] PS00460
Entry type [info] PATTERN
Date [info] MAY-1991 (CREATED); JAN-2008 (DATA UPDATE); MAR-2014 (INFO UPDATE).
PROSITE Doc. [info] PDOC00396

Name and characterization of the entry

Description [info] Glutathione peroxidases active site.
Pattern [info]
[GNDRC]-[RKHNQFYCS]-x-[LIVMFCS]-[LIVMF](2)-x-N-[VT]-x-[STCA]-x-[CU]-
[GA]-x-[TA].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2014_04 which contains 544'996 sequence entries.


Total number of hits 97 in 97 different sequences
Number of true positive hits 97 in 97 different sequences
Number of 'unknown' hits
Number of false positive hits
Number of false negative sequences 15
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 86.61 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info] 1
Site [info] active_site at position 12
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
97 sequences

BSAA_BACHD  (Q9Z9N7), BSAA_BACSU  (P52035), BTUE_ECOLI  (P06610), 
GPO_LACLA   (Q9CFV1), GPO_LACLM   (O32770), GPWA_PSEWI  (O08368), 
GPX1_ARATH  (P52032), GPX1_BOVIN  (P00435), GPX1_CAEEL  (O02621), 
GPX1_CALJA  (Q0EF99), GPX1_CEBAP  (Q4AEI1), GPX1_CHLRE  (P83564), 
GPX1_HELAN  (O23970), GPX1_HUMAN  (P07203), GPX1_HYLLA  (Q4AEI2), 
GPX1_MACFU  (Q865R2), GPX1_MOUSE  (P11352), GPX1_PANTR  (Q0EFA0), 
GPX1_PEA    (O24296), GPX1_PIG    (Q8MJ14), GPX1_PONPY  (Q4AEI3), 
GPX1_RABIT  (P11909), GPX1_RAT    (P04041), GPX1_SCHMA  (Q00277), 
GPX1_SCHPO  (O59858), GPX1_SYNY3  (P74250), GPX1_YEAST  (P36014), 
GPX2_ARATH  (O04922), GPX2_CAEEL  (O62327), GPX2_CALJA  (Q0EF98), 
GPX2_CEBAP  (Q4AEH7), GPX2_HUMAN  (P18283), GPX2_HYLLA  (Q4AEH9), 
GPX2_MACFU  (Q4AEH8), GPX2_MOUSE  (Q9JHC0), GPX2_PONPY  (Q4AEI0), 
GPX2_RAT    (P83645), GPX2_SYNY3  (P73824), GPX2_YEAST  (P38143), 
GPX3_ARATH  (O22850), GPX3_BOVIN  (P37141), GPX3_CAEEL  (Q95003), 
GPX3_CEBAP  (Q4AEH3), GPX3_HUMAN  (P22352), GPX3_HYLLA  (Q4AEH5), 
GPX3_MACFU  (Q4AEH4), GPX3_MOUSE  (P46412), GPX3_PONPY  (Q5RFG3), 
GPX3_RAT    (P23764), GPX3_YEAST  (P40581), GPX41_MOUSE (O70325), 
GPX41_RAT   (P36970), GPX42_MOUSE (Q91XR9), GPX42_RAT   (Q91XR8), 
GPX4_ARATH  (Q8L910), GPX4_BOVIN  (Q9N2J2), GPX4_CALJA  (Q32QL6), 
GPX4_CEBAP  (Q4AEG9), GPX4_CITSI  (Q06652), GPX4_GOSHI  (O49069), 
GPX4_HELAN  (O23968), GPX4_HUMAN  (P36969), GPX4_HYLLA  (Q4AEH1), 
GPX4_MACFU  (Q4AEH0), GPX4_MESCR  (Q9LEF0), GPX4_NICSY  (P30708), 
GPX4_PIG    (P36968), GPX4_PONPY  (Q4AEH2), GPX4_SOLLC  (O24031), 
GPX4_SPIOL  (O23814), GPX4_TOBAC  (Q9FXS3), GPX5_ARATH  (Q9LYB4), 
GPX5_CANFA  (O46607), GPX5_HUMAN  (O75715), GPX5_MACFA  (P28714), 
GPX5_MOUSE  (P21765), GPX5_PIG    (O18994), GPX5_RAT    (P30710), 
GPX6_ARATH  (O48646), GPX6_HUMAN  (P59796), GPX6_MOUSE  (Q91WR8), 
GPX6_RAT    (Q64625), GPX7_ARATH  (Q9SZ54), GPX7_BOVIN  (A6QLY2), 
GPX7_HUMAN  (Q96SL4), GPX7_MOUSE  (Q99LJ6), GPX8_ARATH  (Q8LBU2), 
GPXA_NEIMA  (P0A0T4), GPXA_NEIMB  (P0A0T5), GPXA_NEIMC  (P0C2T0), 
GPXA_NEIMF  (A1KV41), GPXC_BRUMA  (P67877), GPXC_BRUPA  (P67878), 
GPXC_DIRIM  (P52033), GPXC_WUCBA  (P35666), GPX_MCV1    (Q98234), 
GPX_PROCL   (G9JJU2)
» More

UniProtKB/Swiss-Prot
False negative sequences
15 sequences

BSAA_STAAC  (Q5HGC7), BSAA_STAAM  (P64290), BSAA_STAAN  (P99097), 
BSAA_STAAR  (Q6GHD0), BSAA_STAAS  (Q6G9Q8), BSAA_STAAW  (P64291), 
BSAA_STAEQ  (Q5HKZ3), BSAA_STAES  (Q8CSR9), GPX8A_XENLA (Q6IRC8), 
GPX8B_XENLA (Q5U583), GPX8_BOVIN  (Q2NL01), GPX8_DANRE  (Q7ZV14), 
GPX8_HUMAN  (Q8TED1), GPX8_MOUSE  (Q9D7B7), GPX8_TETNG  (Q4RSM6)
» More

UniProtKB/Swiss-Prot
'Partial' sequences
1 sequence

GPX4_PINPS  (P81087)

		
PDB
[Detailed view]
5 PDB

2HE3; 2I3Y; 2OBI; 2P31; 3CMI

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