Entry: PS00485

General information about the entry

Entry name [info] A_DEAMINASE
Accession [info] PS00485
Entry type [info] PATTERN
Date [info] MAY-1991 (CREATED); NOV-1997 (DATA UPDATE); JUN-2016 (INFO UPDATE).
PROSITE Doc. [info] PDOC00419
Associated ProRule [info] PRU10104

Name and characterization of the entry

Description [info] Adenosine and AMP deaminase signature.
Pattern [info]
[SA]-[LIVM]-[NGS]-[STA]-D-D-P.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2016_08 which contains 551'987 sequence entries.


Total number of hits 103 in 103 different sequences
Number of true positive hits 82 in 82 different sequences
Number of 'unknown' hits 0
Number of false positive hits 21 in 21 different sequences
Number of false negative sequences 96
Number of 'partial' sequences 3
Precision (true positives / (true positives + false positives)) 79.61 %
Recall (true positives / (true positives + false negatives)) 46.07 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] active_site(?) at position 5
Site [info] active_site(?) at position 6
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
82 sequences

ADA_BOVIN   (P56658    ), ADA_CHICK   (Q5ZKP6    ), ADA_DANRE   (Q6DG22    ), 
ADA_HUMAN   (P00813    ), ADA_MOUSE   (P03958    ), ADA_RAT     (Q920P6    ), 
ADA_XENLA   (Q6GP70    ), ADA_XENTR   (Q63ZU0    ), ADDL_STRCO  (Q9L0L6    ), 
ADDL_STRVG  (P53984    ), ADD_ECO24   (A7ZM83    ), ADD_ECO27   (B7URW2    ), 
ADD_ECO45   (B7M9X6    ), ADD_ECO55   (B7L5H5    ), ADD_ECO57   (Q8X661    ), 
ADD_ECO5E   (B5Z457    ), ADD_ECO7I   (B7NU11    ), ADD_ECO81   (B7MVA0    ), 
ADD_ECO8A   (B7M0H9    ), ADD_ECOBW   (C4ZY85    ), ADD_ECODH   (B1XF88    ), 
ADD_ECOHS   (A8A0G5    ), ADD_ECOK1   (A1ABG8    ), ADD_ECOL5   (Q0THK5    ), 
ADD_ECOL6   (Q8FH99    ), ADD_ECOLC   (B1IQD2    ), ADD_ECOLI   (P22333    ), 
ADD_ECOLU   (B7NB76    ), ADD_ECOSE   (B6IB57    ), ADD_ECOSM   (B1LER3    ), 
ADD_ECOUT   (Q1RBH5    ), ADD_KLEP3   (B5XWQ7    ), ADD_KLEP7   (A6T9W8    ), 
ADD_PHOLL   (Q7N4H5    ), ADD_PROMH   (B4EVZ1    ), ADD_SALA4   (B5F6I4    ), 
ADD_SALDC   (B5FIE1    ), ADD_SALEP   (B5QUG0    ), ADD_SALG2   (B5RAJ6    ), 
ADD_SALHS   (B4THP5    ), ADD_SALNS   (B4T5A0    ), ADD_SALPC   (C0Q502    ), 
ADD_SALSV   (B4TVC7    ), ADD_SALTI   (Q8Z6R2    ), ADD_SALTY   (Q8ZPL9    ), 
ADD_SERP5   (A8GE12    ), ADD_SHEPC   (A4YCD7    ), ADD_SHESA   (A0L2R5    ), 
ADD_SHESM   (Q0HD92    ), ADD_SHESR   (Q0HPH4    ), ADD_SHESW   (A1RDZ6    ), 
ADD_SHIDS   (Q32FF0    ), ADD_SHIF8   (Q0T4F4    ), ADD_SHIFL   (Q83RC0    ), 
ADD_SHISS   (Q3Z1X8    ), ADD_YERE8   (A1JML4    ), ADD_YERP3   (A7FHX5    ), 
ADD_YERPB   (B2K4L5    ), ADD_YERPS   (Q66AF0    ), ADD_YERPY   (B1JKL9    ), 
ADE_ASPFU   (Q4X1Q4    ), ADE_ASPOR   (Q2TZN9    ), ADE_CANAL   (Q59ZB1    ), 
ADE_CANGA   (Q6FP78    ), ADE_EMENI   (Q8X1T6    ), ADE_GIBZE   (Q4IMJ1    ), 
ADE_KLULA   (Q6CM42    ), ADE_YEAST   (P53909    ), AMPD1_HUMAN (P23109    ), 
AMPD1_MOUSE (Q3V1D3    ), AMPD1_RAT   (P10759    ), AMPD2_HUMAN (Q01433    ), 
AMPD2_MOUSE (Q9DBT5    ), AMPD2_RAT   (Q02356    ), AMPD3_HUMAN (Q01432    ), 
AMPD3_MOUSE (O08739    ), AMPD3_RAT   (O09178    ), AMPD_ARATH  (O80452    ), 
AMPD_DICDI  (Q54DD0    ), AMPD_ORYSJ  (Q84NP7    ), AMPD_SCHPO  (P50998    ), 
AMPD_YEAST  (P15274    )
» more

UniProtKB/Swiss-Prot
False negative sequences
96 sequences

ADALA_XENLA (Q4V831    ), ADAL_BOVIN  (Q0VC13    ), ADAL_CAEEL  (Q8IG39    ), 
ADAL_DANRE  (Q4V9P6    ), ADAL_DROME  (Q9VHH7    ), ADAL_DROPS  (Q295P6    ), 
ADAL_HUMAN  (Q6DHV7    ), ADAL_MOUSE  (Q80SY6    ), ADD1_STRCO  (Q9AK25    ), 
ADD2_STRCO  (Q9X7T2    ), ADDL_OPITP  (B1ZYW1    ), ADDL_TREPA  (O83085    ), 
ADDL_TREPS  (B2S1Z3    ), ADD_CLOAB   (Q97EV1    ), ADD_CLOB1   (A7FSN7    ), 
ADD_CLOB6   (C3L357    ), ADD_CLOBH   (A5I0I2    ), ADD_CLOBJ   (C1FVJ1    ), 
ADD_CLOBK   (B1IHX4    ), ADD_CLOBL   (A7GC28    ), ADD_CLOBM   (B1KY93    ), 
ADD_CLOK1   (B9DZX5    ), ADD_CLOK5   (A5N6F5    ), ADD_CLOP1   (Q0TME7    ), 
ADD_CLOPE   (Q8XHH8    ), ADD_CLOPS   (Q0SQ45    ), ADD_EDWI9   (C5BDE0    ), 
ADD_ENT38   (A4W9X4    ), ADD_ENTFA   (Q839J4    ), ADD_ERWT9   (B2VK11    ), 
ADD_HAEDU   (Q7VNV1    ), ADD_LACC3   (Q036B8    ), ADD_LACCB   (B3W9T6    ), 
ADD_LACLA   (Q9CIR9    ), ADD_MYCA1   (A0QKJ4    ), ADD_MYCA9   (B1MFZ9    ), 
ADD_MYCBO   (P63908    ), ADD_MYCBP   (A1KP00    ), ADD_MYCGI   (A4TEW1    ), 
ADD_MYCLB   (B8ZUW8    ), ADD_MYCLE   (Q9CCL9    ), ADD_MYCMM   (B2HDU8    ), 
ADD_MYCPA   (Q73UD0    ), ADD_MYCSJ   (A3PVY4    ), ADD_MYCSK   (A1UCA4    ), 
ADD_MYCSS   (Q1BCN9    ), ADD_MYCTA   (A5U7Y8    ), ADD_MYCTU   (P63907    ), 
ADD_MYCUA   (A0PNJ1    ), ADD_MYCVP   (A1T5H1    ), ADD_PECAS   (Q6D4X4    ), 
ADD_PECCP   (C6DH28    ), ADD_PSEHT   (Q3IF68    ), ADD_SHEAM   (A1S1P1    ), 
ADD_SHEB2   (B8EDT7    ), ADD_SHEB5   (A3CYL9    ), ADD_SHEB8   (A6WUH7    ), 
ADD_SHEB9   (A9KWZ3    ), ADD_SHEDO   (Q12I24    ), ADD_SHEFN   (Q08A11    ), 
ADD_SHEHH   (B0TT81    ), ADD_SHELP   (A3QJD9    ), ADD_SHEON   (Q8E8D4    ), 
ADD_SHEPA   (A8H819    ), ADD_SHEPW   (B8CV32    ), ADD_SHEWM   (B1KHA6    ), 
ADD_SHIB3   (B2U2C1    ), ADD_SHIBS   (Q320Y0    ), ADD_STRA1   (Q3K2D4    ), 
ADD_STRA3   (P63909    ), ADD_STRA5   (P63910    ), ADD_STRE4   (C0M691    ), 
ADD_STREM   (B4U295    ), ADD_STRMU   (Q8DTN8    ), ADD_STRS7   (C0MHB1    ), 
ADD_STRT2   (Q5M4W6    ), ADD_STRTD   (Q03L81    ), ADD_VIBC3   (A5F4Q2    ), 
ADD_VIBCH   (Q9KNI7    ), ADD_VIBCM   (C3LSH8    ), ADD_VIBF1   (Q5E8Q8    ), 
ADD_VIBFM   (B5FFC4    ), ADD_VIBPA   (Q87TF3    ), ADD_VIBTL   (B7VQ44    ), 
ADD_VIBVU   (Q8D6Q8    ), ADD_VIBVY   (Q7MDL6    ), AGSA_APLCA  (P15287    ), 
CEC1A_DANRE (P58781    ), CECR1_DICDI (Q553U5    ), CECR1_HUMAN (Q9NZK5    ), 
CECR1_PIG   (P58780    ), CECR1_PONAB (Q5RC46    ), CECR1_XENLA (Q2VQV9    ), 
MQNX_ACIC1  (A0LRH8    ), MQNX_STRAW  (Q82K09    ), MQNX_STRCO  (O86737    )
» more

UniProtKB/Swiss-Prot
'Partial' sequences
3 sequences

ADA2_CHICK  (P84520    ), AMPD1_CHICK (P81073    ), AMPD1_RABIT (P81072    )

		
UniProtKB/Swiss-Prot
False positive sequences
21 sequences

CH60_SYNWW  (Q0AVV1    ), CYCH_BRADU  (P45399    ), GIP3_YEAST  (Q03016    ), 
GPL_GLOFF   (Q8MUG0    ), GPR98_HUMAN (Q8WXG9    ), IPYR1_CHLRE (Q93Y52    ), 
ISPD_VIBCH  (Q9KUJ2    ), PURO_NATPD  (Q3ITS6    ), RTC5_AJECN  (A6RBC0    ), 
SOMA_SIGGU  (Q9IBE5    ), SYH_LISIN   (Q92BJ3    ), SYH_LISMF   (Q71ZF0    ), 
SYH_LISMO   (Q8Y708    ), TLN2_HUMAN  (Q9Y4G6    ), UB10A_XENLA (Q2NL57    ), 
UB10B_XENLA (Q7ZXR7    ), UBP10_XENTR (Q6DIJ4    ), URED_ALKEH  (Q0ACA1    ), 
YVRB_BACSU  (O34451    ), ZUPT_XANAC  (Q8PKQ5    ), ZUPT_XANCP  (Q8P8Z6    )
» more

PDB
[Detailed view]
28 PDB

1A4L; 1A4M; 1ADD; 1KRM; 1NDV; 1NDW; 1NDY; 1NDZ; 1O5R; 1QXL; 1UIO; 1UIP; 1UML; 1V79; 1V7A; 1VFL; 1W1I; 1WXY; 1WXZ; 2A3L; 2ADA; 2BGN; 2E1W; 2Z7G; 3IAR; 3KM8; 3MVI; 3MVT
» more

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