PROSITE logo

PROSITE entry PS00509


View entry in original PROSITE format
View entry in raw text format (no links)
View entry auxiliary file in raw text format (no links)
Direct ScanProsite submission
General information about the entry

Entry name [info] RAS_GTPASE_ACTIV_1
Accession [info] PS00509
Entry type [info] PATTERN
Date [info] 01-MAY-1991 CREATED;
01-DEC-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00438

Name and characterization of the entry

Description [info] Ras GTPase-activating proteins domain signature.
Pattern [info] 
[GSNA]-x-[LIVMF]-[FYCI]-[LIVMFY]-R-[LIVMFY](2)-[GACNS]-[PAV]-[AV]-[LIV]-
[LIVM]-[SGANT]-P.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_06 which contains 572'619 sequence entries.


Total number of hits 43 in 43 different sequences
Number of true positive hits 43 in 43 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 13
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 76.79 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 43 sequences 

BUD2_CANAL  (Q5A506), BUD2_YEAST  (P33314), DAB2P_HUMAN (Q5VWQ8), 

DAB2P_MOUSE (Q3UHC7), DAB2P_RAT   (Q6P730), GAP1_CAEEL  (Q22720), 
GAP1_DROME  (P48423), GAP1_SCHPO  (P33277), GAP2_CAEEL  (Q8MLZ5), 
GAP2_DROME  (Q8T498), IQGA1_HUMAN (P46940), IQGA1_MOUSE (Q9JKF1), 
IQGA2_HUMAN (Q13576), IQGA2_MOUSE (Q3UQ44), IQGA3_HUMAN (Q86VI3), 
IRA1_YEAST  (P18963), IRA2_YEAST  (P19158), NF1_HUMAN   (P21359), 
NF1_MOUSE   (Q04690), NF1_RAT (P97526), NGAP_DICDI  (Q54Y08), 
NGAP_HUMAN  (Q9UJF2), RAS4B_HUMAN (C9J798), RASA1_BOVIN (P09851), 
RASA1_HUMAN (P20936), RASA1_RAT   (P50904), RASA2_HUMAN (Q15283), 
RASA2_MOUSE (P58069), RASA2_RAT   (Q63713), RASA3_BOVIN (Q28013), 
RASA3_HUMAN (Q14644), RASA3_MOUSE (Q60790), RASA3_RAT   (Q9QYJ2), 
RASL1_HUMAN (O95294), RASL1_MOUSE (Q9Z268), RASL2_HUMAN (O43374), 
RASL2_MOUSE (Q6PFQ7), RASL3_BOVIN (A6QQ91), RASL3_HUMAN (Q86YV0), 
RASL3_MOUSE (Q8C2K5), SYGP1_HUMAN (Q96PV0), SYGP1_MOUSE (F6SEU4), 
SYGP1_RAT   (Q9QUH6)
» more

UniProtKB/Swiss-Prot
False negative sequences		 13 sequences 

GAPA_DICDI  (O00899), GAPD1_BOVIN (A5D794), GAPD1_HUMAN (Q14C86), 

GAPD1_MOUSE (Q6PAR5), GAPD1_XENLA (A2RV61), IQG1_CANAL  (Q5AH02), 
IQG1_YEAST  (Q12280), NFAA_DICDI  (Q55AR6), RGAA_DICDI  (Q54K32), 
RME6_CAEBR  (A8WVM4), RME6_CAEEL  (Q9GYH7), RME6_DROME  (Q9VZ08), 
RME6_DROPS  (Q29HW3)
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 1 sequence 

NF1_CHICK   (P35608)


				
	

	

		PDB
[Detailed view]		
		
			27 PDB
			


			1NF1; 1WER; 1WQ1; 3BXJ; 3FAY; 5CJP; 6OB2; 6OB3; 6V65; 6V6F; 7MOC; 7MP5; 
			
				7MP6; 7PGP; 7PGQ; 7PGR; 7PGS; 7PGT; 7PGU; 7R03; 7R04; 8BOS; 8E20; 8EDL; 
				8EDM; 8EDN; 8EDO
			
			

			» more