Entry: PS00509

General information about the entry
Entry name RAS_GTPASE_ACTIV_1
Accession number PS00509
Entry type PATTERN
Date MAY-1991 (CREATED); DEC-2004 (DATA UPDATE); MAR-2013 (INFO UPDATE).
PROSITE Documentation PDOC00438
Name and characterization of the entry
DescriptionRas GTPase-activating proteins domain signature.
Pattern [GSNA]-x-[LIVMF]-[FYCI]-[LIVMFY]-R-[LIVMFY](2)-[GACNS]-[PAV]-[AV]-[LIV]- [LIVM]-[SGANT]-P.
Numerical results
  • UniProtKB/Swiss-Prot release number: 2013_05, total number of sequence entries in that release: 540052.
  • Total number of hits in UniProtKB/Swiss-Prot: 42 hits in 42 different sequences
  • Number of hits on proteins that are known to belong to the set under consideration: 42 hits in 42 different sequences
  • Number of hits on proteins that could potentially belong to the set under consideration: 0 hits in 0 different sequences
  • Number of false hits (on unrelated proteins): 0 hits in 0 different sequences
  • Number of known missed hits: 12
  • Number of partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences: 1
  • Precision (true hits / (true hits + false positives)): 100.00 %
  • Recall (true hits / (true hits + false negatives)): 77.78 %
Comments
  • Taxonomic range: Eukaryotes
  • Maximum known number of repetitions of the pattern in a single protein: 1
  • VERSION: 1
Cross-references
UniProtKB/Swiss-Prot True positive hits:
BUD2_YEAST  (P33314), DAB2P_HUMAN (Q5VWQ8), DAB2P_MOUSE (Q3UHC7), 
DAB2P_RAT   (Q6P730), GAP1_CAEEL  (Q22720), GAP1_DROME  (P48423), 
GAP1_SCHPO  (P33277), GAP2_CAEEL  (Q8MLZ5), GAP2_DROME  (Q8T498), 
IQGA1_HUMAN (P46940), IQGA1_MOUSE (Q9JKF1), IQGA2_HUMAN (Q13576), 
IQGA2_MOUSE (Q3UQ44), IQGA3_HUMAN (Q86VI3), IRA1_YEAST  (P18963), 
IRA2_YEAST  (P19158), NF1_HUMAN   (P21359), NF1_MOUSE   (Q04690), 
NF1_RAT     (P97526), NGAP_DICDI  (Q54Y08), NGAP_HUMAN  (Q9UJF2), 
RAS4B_HUMAN (C9J798), RASA1_BOVIN (P09851), RASA1_HUMAN (P20936), 
RASA1_RAT   (P50904), RASA2_HUMAN (Q15283), RASA2_MOUSE (P58069), 
RASA2_RAT   (Q63713), RASA3_BOVIN (Q28013), RASA3_HUMAN (Q14644), 
RASA3_MOUSE (Q60790), RASA3_RAT   (Q9QYJ2), RASL1_HUMAN (O95294), 
RASL1_MOUSE (Q9Z268), RASL2_HUMAN (O43374), RASL2_MOUSE (Q6PFQ7), 
RASL3_BOVIN (A6QQ91), RASL3_HUMAN (Q86YV0), RASL3_MOUSE (Q8C2K5), 
SYGP1_HUMAN (Q96PV0), SYGP1_MOUSE (F6SEU4), SYGP1_RAT   (Q9QUH6)
False negative hits (sequences which belong to the set under consideration, but which have not been picked up by the pattern or profile):
GAPA_DICDI  (O00899), GAPD1_BOVIN (A5D794), GAPD1_HUMAN (Q14C86), 
GAPD1_MOUSE (Q6PAR5), GAPD1_XENLA (A2RV61), IQG1_YEAST  (Q12280), 
NFAA_DICDI  (Q55AR6), RGAA_DICDI  (Q54K32), RME6_CAEBR  (A8WVM4), 
RME6_CAEEL  (Q9GYH7), RME6_DROME  (Q9VZ08), RME6_DROPS  (Q29HW3)
`Potential' hits (partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences):
NF1_CHICK   (P35608)
Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:

[Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format]

Retrieve the sequence logo from the alignment

PDB
[Detailed view]		 1NF1; 1WER; 1WQ1; 3BXJ;

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