PROSITE logo

PROSITE entry PS00601


View entry in original PROSITE format
View entry in raw text format (no links)
View entry auxiliary file in raw text format (no links)
Direct ScanProsite submission
General information about the entry

Entry name [info] IRF_1
Accession [info] PS00601
Entry type [info] PATTERN
Date [info] 01-DEC-1991 CREATED;
01-JUL-1998 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00522

Name and characterization of the entry

Description [info] IRF tryptophan pentad repeat DNA-binding domain signature.
Pattern [info]
W-x-[DNH]-x(5)-[LIVF]-x-[IV]-P-W-x-H-x(9,10)-[DE]-x(2)-[LIVF]-F-[KRQ]-x-
[WR]-A.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_06 which contains 572'619 sequence entries.


Total number of hits 29 in 29 different sequences
Number of true positive hits 29 in 29 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 5
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 85.29 %

Comments [info]

Taxonomic range [info] Eukaryotes, Eukaryotic viruses
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
29 sequences

IRF1_BOVIN  (Q3SZP0), IRF1_CHICK  (Q90876), IRF1_HUMAN  (P10914), 
IRF1_MOUSE  (P15314), IRF1_PIG(A0FIN4), IRF1_RAT(P23570), 
IRF2_CHICK  (Q98925), IRF2_HUMAN  (P14316), IRF2_MOUSE  (P23906), 
IRF2_SIGHI  (Q8R4E0), IRF3_CHICK  (Q90643), IRF3_HUMAN  (Q14653), 
IRF3_MOUSE  (P70671), IRF3_PIG(Q764M6), IRF4_HUMAN  (Q15306), 
IRF4_MOUSE  (Q64287), IRF5_BOVIN  (Q58DJ0), IRF5_HUMAN  (Q13568), 
IRF5_MOUSE  (P56477), IRF6_BOVIN  (Q08DD6), IRF6_HUMAN  (O14896), 
IRF6_MOUSE  (P97431), IRF7_HUMAN  (Q92985), IRF7_MOUSE  (P70434), 
IRF8_CHICK  (Q90871), IRF8_HUMAN  (Q02556), IRF8_MOUSE  (P23611), 
IRF9_HUMAN  (Q00978), IRF9_MOUSE  (Q61179)
» more

UniProtKB/Swiss-Prot
False negative sequences
5 sequences

IRF3_BOVIN  (Q4JF28), VIRF1_HHV8P (F5HF68), VIRF2_HHV8P (Q2HR71), 
VIRF3_HHV8P (F5HIC6), VIRF4_HHV8P (Q2HR73)
» more

PDB
[Detailed view]
17 PDB

1IF1; 1IRF; 1IRG; 1T2K; 2DLL; 2IRF; 2O61; 2O6G; 2PI0; 3QU3; 3QU6; 6TD4; 7JM4; 7O56; 7OGS; 7OOT; 7RH2
» more