Entry: PS00606

General information about the entry
Entry name B_KETOACYL_SYNTHASE
Accession number PS00606
Entry type PATTERN
Date DEC-1991 (CREATED); APR-2006 (DATA UPDATE); MAR-2013 (INFO UPDATE).
PROSITE Documentation PDOC00529
Associated ProRule PRU10022
Name and characterization of the entry
DescriptionBeta-ketoacyl synthases active site.
Pattern G-{A}-{KGR}-x(2)-[LIVMFTAP]-{R}-x-[AGC]-C-[STA](2)-[STAG]-x(2)-{LI}- [LIVMF].
Numerical results
  • UniProtKB/Swiss-Prot release number: 2013_05, total number of sequence entries in that release: 540052.
  • Total number of hits in UniProtKB/Swiss-Prot: 143 hits in 136 different sequences
  • Number of hits on proteins that are known to belong to the set under consideration: 134 hits in 127 different sequences
  • Number of hits on proteins that could potentially belong to the set under consideration: 0 hits in 0 different sequences
  • Number of false hits (on unrelated proteins): 9 hits in 9 different sequences
  • Number of known missed hits: 8
  • Number of partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences: 2
  • Precision (true hits / (true hits + false positives)): 93.71 %
  • Recall (true hits / (true hits + false negatives)): 94.37 %
Comments
  • Taxonomic range: Eukaryotes, Prokaryotes (Bacteria)
  • Maximum known number of repetitions of the pattern in a single protein: 2
  • `Interesting' site in the pattern: 9,active_site
  • VERSION: 2
Cross-references
UniProtKB/Swiss-Prot True positive hits:
CEM1_YEAST  (P39525), ERYA1_SACER (Q03131), ERYA2_SACER (Q03132), 
ERYA3_SACER (Q03133), FABB_BUCAI  (P57193), FABB_BUCAP  (Q8KA28), 
FABB_BUCBP  (Q89AY4), FABB_ECOL6  (P0A954), FABB_ECOLI  (P0A953), 
FABB_HAEIN  (P43710), FABF_BACSU  (O34340), FABF_COXBU  (Q83E37), 
FABF_ECO57  (P0AAI7), FABF_ECOL6  (P0AAI6), FABF_ECOLI  (P0AAI5), 
FABF_RHIME  (P56902), FABF_SHIFL  (P0AAI8), FABF_STAAC  (Q5HHA1), 
FABF_STAAM  (Q99VA6), FABF_STAAN  (Q7A6F8), FABF_STAAR  (Q6GIA3), 
FABF_STAAS  (Q6GAU2), FABF_STAAU  (Q5TKS0), FABF_STAAW  (Q8NXE1), 
FABF_SYNY3  (P73283), FABF_VIBCH  (Q9KQH9), FABF_VIBHA  (P55338), 
FAS2_CANAX  (P43098), FAS2_CANPC  (G8BAW7), FAS2_EMEND  (P78615), 
FAS2_EMENI  (Q5B7V0), FAS2_LACKL  (Q765N2), FAS2_PENPA  (P15368), 
FAS2_SCHPO  (Q10289), FAS2_YEAST  (P19097), FAS_ANSAN   (P36189), 
FAS_BOVIN   (Q71SP7), FAS_CHICK   (P12276), FAS_HUMAN   (P49327), 
FAS_MOUSE   (P19096), FAS_RAT     (P12785), KAS1_STRCM  (P41175), 
KAS1_STRCN  (Q02578), KAS1_STRCO  (P23155), KAS1_STRGA  (P16538), 
KAS1_STRHA  (Q05356), KAS1_STRRM  (P43678), KAS1_STRVN  (P16540), 
KASA_STRCO  (Q02059), KASC1_ARATH (P52410), KASC1_HORVU (P23902), 
KASC2_ARATH (Q9C9P4), KASM_ARATH  (Q8L3X9), LNKS_ASPTE  (Q9Y8A5), 
LNKS_ASPTN  (Q0C8M3), MCAS_MYCBO  (Q02251), MSAS_PENPA  (P22367), 
MSL7_MYCBO  (Q7TXK8), MSL7_MYCMM  (B2HIL7), MYCA_BACIU  (Q9R9J1), 
NODE_RHILT  (P04684), NODE_RHILV  (P04683), NODE_RHIME  (P06230), 
NODE_RHIS3  (P72331), NOE4_RHIML  (P06231), NRP14_ASPFU (Q4WAZ9), 
OL56_STRAT  (Q07017), OXSM_BOVIN  (Q0VCA7), OXSM_HUMAN  (Q9NWU1), 
OXSM_MOUSE  (Q9D404), PHAS_MYCBO  (Q7TVK8), PHAS_MYCBP  (A1KQG0), 
PHAS_MYCTA  (A5U9F4), PHAS_MYCTU  (O07798), PKS10_DICDI (B0G103), 
PKS13_DICDI (Q559A9), PKS14_DICDI (Q558Y6), PKS15_MYCTU (P96284), 
PKS16_DICDI (Q869W9), PKS17_DICDI (Q869X2), PKS18_DICDI (Q54TW0), 
PKS19_DICDI (Q54T36), PKS1_DICDI  (Q55E72), PKS21_DICDI (B0G138), 
PKS22_DICDI (Q54QD3), PKS23_DICDI (Q54QD1), PKS24_DICDI (Q54KU5), 
PKS25_DICDI (Q54KU3), PKS27_DICDI (Q54G30), PKS28_DICDI (B0G170), 
PKS29_DICDI (Q54FQ3), PKS2_DICDI  (Q55DM7), PKS30_DICDI (Q54FQ2), 
PKS31_DICDI (Q54FQ1), PKS32_DICDI (Q54FP8), PKS33_DICDI (Q54FN7), 
PKS34_DICDI (Q54FN2), PKS37_DICDI (Q54FI3), PKS38_DICDI (Q54FD2), 
PKS39_DICDI (Q54FC8), PKS3_DICDI  (Q55CN6), PKS40_DICDI (Q54ED7), 
PKS41_DICDI (Q54ED6), PKS42_DICDI (Q54D44), PKS44_DICDI (Q54B51), 
PKS5_DICDI  (Q86JI5), PKS6_DICDI  (B0G0Z9), PKS7_DICDI  (B0G100), 
PKS8_DICDI  (B0G101), PKS9_DICDI  (Q86AE3), PKSJ_BACSU  (P40806), 
PKSL_BACSU  (Q05470), PKSM_BACSU  (P40872), PKSN_BACSU  (O31782), 
PKSR_BACSU  (O31784), PPSA_MYCBO  (Q7TXM0), PPSA_MYCTU  (Q10977), 
PPSB_MYCBO  (Q7TXL9), PPSB_MYCTU  (Q10978), PPSC_MYCBO  (Q7TXL8), 
PPSC_MYCTU  (P96202), PPSD_MYCBO  (Q7TXL7), PPSD_MYCTU  (P96203), 
PPSE_MYCBO  (Q7TXL6), PPSE_MYCTU  (P96204), STCJ_EMENI  (Q00681), 
WA_EMENI    (Q03149)
False negative hits (sequences which belong to the set under consideration, but which have not been picked up by the pattern or profile):
FAB1_MYCBO  (P63455), FAB1_MYCLE  (Q9CBS7), FAB1_MYCTU  (P63454), 
FAB2_MYCBO  (P63457), FAB2_MYCLE  (O69473), FAB2_MYCTU  (P63456), 
PKS26_DICDI (Q54IX3), PKS45_DICDI (Q54B49)
`Potential' hits (partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences):
FAS_CAPHI   (P08757), FAS_RABIT   (P07855)
False positive hits (sequences which do not belong to the set under consideration):
GLPB_HAEDU  (Q7VM49), KDSB_MYXXD  (Q1DDB3), MDH_PSYIN   (A1SRP8), 
MNMG_ERYLH  (Q2N6I8), NEUA_BOVIN  (Q3SZM5), NEUA_HUMAN  (Q8NFW8), 
NEUA_PONAB  (Q5R6R5), PUS5_ORYSJ  (Q0DST9), Y1105_ARATH (O04086)
Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:

[Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format]

Retrieve the sequence logo from the alignment

PDB
[Detailed view]		 1B3N; 1DD8; 1E5M; 1FJ4; 1FJ8; 1G5X; 1H4F; 1KAS; 1QXG; 1TQY; 1W0I; 2AQ7; 2AQB; 2BUH; 2BUI; 2BYW; 2BYX; 2BYY; 2BYZ; 2BZ3; 2BZ4; 2GFW; 2GFY; 2GQD; 2HG4; 2IWY; 2IWZ; 2IX4; 2PFF; 2QO3; 2UV8; 2VB7; 2VB8; 2VB9; 2VBA; 2VKZ; 3HHD; 3HMJ;

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