Entry: PS00720

General information about the entry

Entry name [info] RASGEF
Accession [info] PS00720
Entry type [info] PATTERN
Date [info] DEC-1992 (CREATED); APR-2003 (DATA UPDATE); JUN-2015 (INFO UPDATE).
PROSITE Doc. [info] PDOC00594

Name and characterization of the entry

Description [info] Ras Guanine-nucleotide exchange factors domain signature.
Pattern [info]
[VI]-P-[FYWVI]-x-[GPSV]-x(2)-[LIVMFYK]-x-[DNE]-[LIVM]-x(13,35)-[IVL]-N-
[FYME]-x-K.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2015_08 which contains 320'201 sequence entries.


Total number of hits 67 in 67 different sequences
Number of true positive hits 67 in 67 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 66
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 50.38 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
67 sequences

BUD5_YEAST  (P25300), C3G_DROME   (O77086), CDC25_CANAL (P43069), 
CDC25_LACKL (Q02342), CDC25_YEAST (P04821), GEFB_DICDI  (Q8IS21), 
GEFC_DICDI  (Q8IS20), GEFK_DICDI  (Q54FF3), GEFS_DICDI  (Q8SSW7), 
GEFV_DICDI  (Q55FD8), GEFW_DICDI  (Q55GH9), GNDS_HUMAN  (Q12967), 
GNDS_MOUSE  (Q03385), GNDS_RAT    (Q03386), LTE1_ASHGO  (Q75BH9), 
LTE1_CANGA  (Q6FT12), LTE1_KLULA  (Q6CY10), LTE1_YEAST  (P07866), 
RG1BA_DANRE (Q6DHR3), RG1BB_DANRE (Q6DBW1), RGF1B_BOVIN (A4IFE4), 
RGF1B_HUMAN (Q0VAM2), RGF1B_MOUSE (Q8JZL7), RGF1B_PONAB (Q5RC04), 
RGF1B_XENTR (Q28EC1), RGF1C_HUMAN (Q8N431), RGF1C_MACFA (Q95KH6), 
RGF1C_MOUSE (Q9D300), RGL1_DANRE  (Q6P112), RGL1_HUMAN  (Q9NZL6), 
RGL1_MOUSE  (Q60695), RGL2_CANFA  (Q5TJE5), RGL2_HUMAN  (O15211), 
RGL2_MOUSE  (Q61193), RGL3_HUMAN  (Q3MIN7), RGL3_MOUSE  (Q3UYI5), 
RGRF1_HUMAN (Q13972), RGRF1_MOUSE (P27671), RGRF1_RAT   (P28818), 
RGRF2_DANRE (A2CEA7), RGRF2_HUMAN (O14827), RGRF2_MOUSE (P70392), 
RGRF2_RAT   (Q99JE4), RPGF1_CAEEL (P34578), RPGF1_HUMAN (Q13905), 
RPGF3_HUMAN (O95398), RPGF3_MOUSE (Q8VCC8), RPGF3_RAT   (Q9Z1C8), 
RPGF4_HUMAN (Q8WZA2), RPGF4_MOUSE (Q9EQZ6), RPGF4_RAT   (Q9Z1C7), 
RPGF5_HUMAN (Q92565), RPGF5_MOUSE (Q8C0Q9), RPGF5_RAT   (P83900), 
RPGF_CAEEL  (G5EDB9), SDC25_YEAS1 (B3LTF3), SDC25_YEAS6 (B5VMS9), 
SDC25_YEAS7 (A7A0P0), SDC25_YEAS8 (C8ZCV7), SDC25_YEASX (P0CF32), 
SOS1_HUMAN  (Q07889), SOS1_MOUSE  (Q62245), SOS2_HUMAN  (Q07890), 
SOS2_MOUSE  (Q02384), SOS_DROME   (P26675), STE6_SCHPO  (P26674), 
YL016_YEAST (P0CF34)
» More

UniProtKB/Swiss-Prot
False negative sequences
66 sequences

BCAR3_BOVIN (Q58DL5), BCAR3_HUMAN (O75815), BCAR3_MACFA (Q4R8R1), 
BCAR3_MOUSE (Q9QZK2), BCAR3_XENLA (Q6INP9), BEM2_YEAST  (P39960), 
EFC25_SCHPO (Q9USU1), GBPC_DICDI  (Q8MVR1), GBPD_DICDI  (Q54S40), 
GEFA_DICDI  (Q54PQ4), GEFD_DICDI  (Q8IS19), GEFE_DICDI  (Q8IS18), 
GEFF_DICDI  (Q54C94), GEFG_DICDI  (Q8ST25), GEFH_DICDI  (Q8IS16), 
GEFI_DICDI  (Q8IS15), GEFJ_DICDI  (Q8IS14), GEFL_DICDI  (B0M0P8), 
GEFM_DICDI  (Q8SSQ3), GEFN_DICDI  (Q8IS12), GEFO_DICDI  (Q8IS11), 
GEFP_DICDI  (Q54TK8), GEFQ_DICDI  (Q86G47), GEFR_DICDI  (Q8SSQ0), 
GEFX_DICDI  (Q55EC7), GEFY_DICDI  (Q552M5), GRP1_HUMAN  (O95267), 
GRP1_MOUSE  (Q9Z1S3), GRP1_RAT    (Q9R1K8), GRP1_XENLA  (Q6NTL4), 
GRP1_XENTR  (A4IJ06), GRP2A_XENLA (Q32N25), GRP2B_XENLA (Q6DCK3), 
GRP2_BOVIN  (A6N9I4), GRP2_HUMAN  (Q7LDG7), GRP2_MOUSE  (Q9QUG9), 
GRP2_RAT    (P0C643), GRP4_BOVIN  (Q1LZ97), GRP4_HUMAN  (Q8TDF6), 
GRP4_MOUSE  (Q8BTM9), GRP4_RAT    (Q8R5I4), PLCE1_HUMAN (Q9P212), 
PLCE1_MOUSE (Q8K4S1), PLCE1_RAT   (Q99P84), RGDSR_HUMAN (Q8IZJ4), 
RGF1A_HUMAN (Q8N9B8), RGF1A_XENTR (A0JM95), RGPS1_CHICK (Q5ZJK0), 
RGPS1_DANRE (B0UXH6), RGPS1_HUMAN (Q5JS13), RGPS1_MOUSE (A2AR50), 
RGPS2_HUMAN (Q86X27), RGPS2_MACFA (Q4R7W3), RGPS2_MOUSE (Q9ERD6), 
RPGF2_BOVIN (F1MSG6), RPGF2_CANFA (F1PBJ0), RPGF2_HUMAN (Q9Y4G8), 
RPGF2_MOUSE (Q8CHG7), RPGF2_RAT   (F1M386), RPGFL_HUMAN (Q9UHV5), 
RPGFL_MOUSE (Q68EF8), RPGFL_PONPY (Q5R9B2), SH2D3_HUMAN (Q8N5H7), 
SH2D3_MOUSE (Q9QZS8), VKIND_HUMAN (Q76NI1), VKIND_MOUSE (Q0KK55)
» More

PDB
[Detailed view]
32 PDB

1BKD; 1NVU; 1NVV; 1NVW; 1NVX; 1XD2; 1XD4; 1XDV; 2BYV; 2II0; 2IJE; 3CF6; 3KSY; 4F7Z; 4JGW; 4MGI; 4MGK; 4MGY; 4MGZ; 4MH0; 4NYI; 4NYJ; 4NYM; 4URU; 4URV; 4URW; 4URX; 4URY; 4URZ; 4US0; 4US1; 4US2
» More

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