Entry: PS00760

General information about the entry

Entry name [info] SPASE_I_2
Accession [info] PS00760
Entry type [info] PATTERN
Date [info] DEC-1992 (CREATED); DEC-2004 (DATA UPDATE); JUN-2015 (INFO UPDATE).
PROSITE Doc. [info] PDOC00418
Associated ProRule [info] PRU10098

Name and characterization of the entry

Description [info] Signal peptidases I lysine active site.
Pattern [info]
K-R-[LIVMSTA](2)-[GA]-x-[PG]-G-[DEQ]-x-[LIVM]-x-[LIVMFY].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2015_08 which contains 320'201 sequence entries.


Total number of hits 46 in 46 different sequences
Number of true positive hits 44 in 44 different sequences
Number of 'unknown' hits 0
Number of false positive hits 2 in 2 different sequences
Number of false negative sequences 22
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 95.65 %
Recall (true positives / (true positives + false negatives)) 66.67 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] active_site at position 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
44 sequences

IMP1_SCHPO  (O74800), IMP1_YEAST  (P28627), LEP1_BACAM  (P41026), 
LEP1_SYNY3  (P72660), LEP2_BACAM  (P41025), LEP2_SYNY3  (P73157), 
LEPP_BACNA  (P37943), LEPQ_BACNA  (Q57350), LEPS_BACSU  (P28628), 
LEPT_BACSU  (P71013), LEPU_BACSU  (P42959), LEPV_BACSU  (O07560), 
LEP_AQUAE   (O67088), LEP_BACCL   (P41027), LEP_BACLI   (P42668), 
LEP_BUCAI   (P57347), LEP_BUCAP   (Q8K9R0), LEP_BUCBP   (Q89AM6), 
LEP_ECOLI   (P00803), LEP_HAEIN   (P44454), LEP_PHOLA   (Q51876), 
LEP_PSEAE   (Q9I5G7), LEP_PSEFL   (P26844), LEP_RICAH   (A8GM78), 
LEP_RICB8   (A8GYE1), LEP_RICBR   (Q1RHA1), LEP_RICCK   (A8EXI2), 
LEP_RICCN   (Q92JB1), LEP_RICFE   (Q4UKA7), LEP_RICM5   (A8F0M1), 
LEP_RICPR   (Q9ZE32), LEP_RICRS   (A8GQT7), LEP_RICTY   (Q8L2J7), 
LEP_SALTI   (P0A1W3), LEP_SALTY   (P0A1W2), LEP_STAAC   (Q5HHB9), 
LEP_STAAM   (P0A067), LEP_STAAN   (P0A068), LEP_STAAR   (Q6GIC3), 
LEP_STAAS   (Q6GAW1), LEP_STAAU   (P0A070), LEP_STAAW   (P0A069), 
LEP_STRPN   (O07344), LEP_STRR6   (P59662)
» More

UniProtKB/Swiss-Prot
False negative sequences
22 sequences

IMP1L_HUMAN (Q96LU5), IMP1L_MOUSE (Q9CQU8), IMP1L_XENTR (Q28I39), 
IMP2L_BOVIN (Q2KI92), IMP2L_DANRE (Q6AZD4), IMP2L_HUMAN (Q96T52), 
IMP2L_MOUSE (Q8BPT6), IMP2L_SCHPO (Q9UST2), IMP2L_XENLA (Q5PQ63), 
IMP2_YEAST  (P46972), LEPH_STAAC  (Q5HHC0), LEPH_STAAM  (P0A063), 
LEPH_STAAN  (P0A064), LEPH_STAAR  (Q6GIC4), LEPH_STAAS  (Q6GAW2), 
LEPH_STAAU  (P0A066), LEPH_STAAW  (P0A065), LEP_HELPJ   (Q9ZLQ5), 
LEP_HELPY   (O25300), LEP_MYCLE   (O33021), LEP_MYCTO   (P9WKA0), 
LEP_MYCTU   (P9WKA1)
» More

UniProtKB/Swiss-Prot
False positive sequences
2 sequences

RL18_THEAN  (Q4UFD5), RL18_THEPA  (Q4N438)

		
PDB
[Detailed view]
5 PDB

1B12; 1KN9; 1T7D; 3IIQ; 3S04

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