Entry: PS00760

General information about the entry
Entry name SPASE_I_2
Accession number PS00760
Entry type PATTERN
Date DEC-1992 (CREATED); DEC-2004 (DATA UPDATE); MAR-2013 (INFO UPDATE).
PROSITE Documentation PDOC00418
Associated ProRule PRU10098
Name and characterization of the entry
DescriptionSignal peptidases I lysine active site.
Pattern K-R-[LIVMSTA](2)-[GA]-x-[PG]-G-[DEQ]-x-[LIVM]-x-[LIVMFY].
Numerical results
  • UniProtKB/Swiss-Prot release number: 2013_05, total number of sequence entries in that release: 540052.
  • Total number of hits in UniProtKB/Swiss-Prot: 46 hits in 46 different sequences
  • Number of hits on proteins that are known to belong to the set under consideration: 44 hits in 44 different sequences
  • Number of hits on proteins that could potentially belong to the set under consideration: 0 hits in 0 different sequences
  • Number of false hits (on unrelated proteins): 2 hits in 2 different sequences
  • Number of known missed hits: 21
  • Number of partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences: 0
  • Precision (true hits / (true hits + false positives)): 95.65 %
  • Recall (true hits / (true hits + false negatives)): 67.69 %
Comments
  • Taxonomic range: Eukaryotes, Prokaryotes (Bacteria)
  • Maximum known number of repetitions of the pattern in a single protein: 1
  • `Interesting' site in the pattern: 1,active_site
  • VERSION: 1
Cross-references
UniProtKB/Swiss-Prot True positive hits:
IMP1_SCHPO  (O74800), IMP1_YEAST  (P28627), LEP1_BACAM  (P41026), 
LEP1_SYNY3  (P72660), LEP2_BACAM  (P41025), LEP2_SYNY3  (P73157), 
LEPP_BACNA  (P37943), LEPQ_BACNA  (Q57350), LEPS_BACSU  (P28628), 
LEPT_BACSU  (P71013), LEPU_BACSU  (P42959), LEPV_BACSU  (O07560), 
LEP_AQUAE   (O67088), LEP_BACCL   (P41027), LEP_BACLI   (P42668), 
LEP_BUCAI   (P57347), LEP_BUCAP   (Q8K9R0), LEP_BUCBP   (Q89AM6), 
LEP_ECOLI   (P00803), LEP_HAEIN   (P44454), LEP_PHOLA   (Q51876), 
LEP_PSEAE   (Q9I5G7), LEP_PSEFL   (P26844), LEP_RICAH   (A8GM78), 
LEP_RICB8   (A8GYE1), LEP_RICBR   (Q1RHA1), LEP_RICCK   (A8EXI2), 
LEP_RICCN   (Q92JB1), LEP_RICFE   (Q4UKA7), LEP_RICM5   (A8F0M1), 
LEP_RICPR   (Q9ZE32), LEP_RICRS   (A8GQT7), LEP_RICTY   (Q8L2J7), 
LEP_SALTI   (P0A1W3), LEP_SALTY   (P0A1W2), LEP_STAAC   (Q5HHB9), 
LEP_STAAM   (P0A067), LEP_STAAN   (P0A068), LEP_STAAR   (Q6GIC3), 
LEP_STAAS   (Q6GAW1), LEP_STAAU   (P0A070), LEP_STAAW   (P0A069), 
LEP_STRPN   (O07344), LEP_STRR6   (P59662)
False negative hits (sequences which belong to the set under consideration, but which have not been picked up by the pattern or profile):
IMP1L_HUMAN (Q96LU5), IMP1L_MOUSE (Q9CQU8), IMP1L_XENTR (Q28I39), 
IMP2L_BOVIN (Q2KI92), IMP2L_DANRE (Q6AZD4), IMP2L_HUMAN (Q96T52), 
IMP2L_MOUSE (Q8BPT6), IMP2L_SCHPO (Q9UST2), IMP2L_XENLA (Q5PQ63), 
IMP2_YEAST  (P46972), LEPH_STAAC  (Q5HHC0), LEPH_STAAM  (P0A063), 
LEPH_STAAN  (P0A064), LEPH_STAAR  (Q6GIC4), LEPH_STAAS  (Q6GAW2), 
LEPH_STAAU  (P0A066), LEPH_STAAW  (P0A065), LEP_HELPJ   (Q9ZLQ5), 
LEP_HELPY   (O25300), LEP_MYCLE   (O33021), LEP_MYCTU   (Q10789)
False positive hits (sequences which do not belong to the set under consideration):
RL18_THEAN  (Q4UFD5), RL18_THEPA  (Q4N438)
Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:

[Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format]

Retrieve the sequence logo from the alignment

PDB
[Detailed view]		 1B12; 1KN9; 1T7D; 3IIQ; 3S04;

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