Entry: PS00760

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General information about the entry

Entry name [info] SPASE_I_2
Accession [info] PS00760
Entry type [info] PATTERN
Date [info] DEC-1992 (CREATED); DEC-2004 (DATA UPDATE); MAR-2014 (INFO UPDATE).
PROSITE Doc. [info] PDOC00418
Associated ProRule [info] PRU10098

Name and characterization of the entry

Description [info] Signal peptidases I lysine active site.
Pattern [info]
K-R-[LIVMSTA](2)-[GA]-x-[PG]-G-[DEQ]-x-[LIVM]-x-[LIVMFY].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2014_04 which contains 544'996 sequence entries.


Total number of hits 46 in 46 different sequences
Number of true positive hits 44 in 44 different sequences
Number of 'unknown' hits
Number of false positive hits 2 in 2 different sequences
Number of false negative sequences 22
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 95.65 %
Recall (true positives / (true positives + false negatives)) 66.67 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] active_site at position 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
44 sequences

IMP1_SCHPO  (O74800), IMP1_YEAST  (P28627), LEP1_BACAM  (P41026), 
LEP1_SYNY3  (P72660), LEP2_BACAM  (P41025), LEP2_SYNY3  (P73157), 
LEPP_BACNA  (P37943), LEPQ_BACNA  (Q57350), LEPS_BACSU  (P28628), 
LEPT_BACSU  (P71013), LEPU_BACSU  (P42959), LEPV_BACSU  (O07560), 
LEP_AQUAE   (O67088), LEP_BACCL   (P41027), LEP_BACLI   (P42668), 
LEP_BUCAI   (P57347), LEP_BUCAP   (Q8K9R0), LEP_BUCBP   (Q89AM6), 
LEP_ECOLI   (P00803), LEP_HAEIN   (P44454), LEP_PHOLA   (Q51876), 
LEP_PSEAE   (Q9I5G7), LEP_PSEFL   (P26844), LEP_RICAH   (A8GM78), 
LEP_RICB8   (A8GYE1), LEP_RICBR   (Q1RHA1), LEP_RICCK   (A8EXI2), 
LEP_RICCN   (Q92JB1), LEP_RICFE   (Q4UKA7), LEP_RICM5   (A8F0M1), 
LEP_RICPR   (Q9ZE32), LEP_RICRS   (A8GQT7), LEP_RICTY   (Q8L2J7), 
LEP_SALTI   (P0A1W3), LEP_SALTY   (P0A1W2), LEP_STAAC   (Q5HHB9), 
LEP_STAAM   (P0A067), LEP_STAAN   (P0A068), LEP_STAAR   (Q6GIC3), 
LEP_STAAS   (Q6GAW1), LEP_STAAU   (P0A070), LEP_STAAW   (P0A069), 
LEP_STRPN   (O07344), LEP_STRR6   (P59662)
» More

UniProtKB/Swiss-Prot
False negative sequences
22 sequences

IMP1L_HUMAN (Q96LU5), IMP1L_MOUSE (Q9CQU8), IMP1L_XENTR (Q28I39), 
IMP2L_BOVIN (Q2KI92), IMP2L_DANRE (Q6AZD4), IMP2L_HUMAN (Q96T52), 
IMP2L_MOUSE (Q8BPT6), IMP2L_SCHPO (Q9UST2), IMP2L_XENLA (Q5PQ63), 
IMP2_YEAST  (P46972), LEPH_STAAC  (Q5HHC0), LEPH_STAAM  (P0A063), 
LEPH_STAAN  (P0A064), LEPH_STAAR  (Q6GIC4), LEPH_STAAS  (Q6GAW2), 
LEPH_STAAU  (P0A066), LEPH_STAAW  (P0A065), LEP_HELPJ   (Q9ZLQ5), 
LEP_HELPY   (O25300), LEP_MYCLE   (O33021), LEP_MYCTO   (P9WKA0), 
LEP_MYCTU   (P9WKA1)
» More

UniProtKB/Swiss-Prot
False positive sequences
2 sequences

RL18_THEAN  (Q4UFD5), RL18_THEPA  (Q4N438)

		
PDB
[Detailed view]
5 PDB

1B12; 1KN9; 1T7D; 3IIQ; 3S04

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