Entry: PS00798

General information about the entry
Entry name ALDOKETO_REDUCTASE_1
Accession number PS00798
Entry type PATTERN
Date DEC-1992 (CREATED); APR-2006 (DATA UPDATE); MAR-2013 (INFO UPDATE).
PROSITE Documentation PDOC00061
Name and characterization of the entry
DescriptionAldo/keto reductase family signature 1.
Pattern G-[FY]-R-[HSAL]-[LIVMF]-D-[STAGCL]-[AS]-x(5)-[EQ]-x(2)-[LIVMCA]-[GS].
Numerical results
  • UniProtKB/Swiss-Prot release number: 2013_05, total number of sequence entries in that release: 540052.
  • Total number of hits in UniProtKB/Swiss-Prot: 131 hits in 131 different sequences
  • Number of hits on proteins that are known to belong to the set under consideration: 131 hits in 131 different sequences
  • Number of hits on proteins that could potentially belong to the set under consideration: 0 hits in 0 different sequences
  • Number of false hits (on unrelated proteins): 0 hits in 0 different sequences
  • Number of known missed hits: 44
  • Number of partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences: 3
  • Precision (true hits / (true hits + false positives)): 100.00 %
  • Recall (true hits / (true hits + false negatives)): 74.86 %
Comments
  • Taxonomic range: Eukaryotes, Prokaryotes (Bacteria)
  • Maximum known number of repetitions of the pattern in a single protein: 1
  • VERSION: 2
Cross-references
UniProtKB/Swiss-Prot True positive hits:
6DCS_SOYBN  (P26690), A1A1A_DANRE (Q6AZW2), A1A1B_DANRE (Q568L5), 
AK1A1_BOVIN (Q3ZCJ2), AK1A1_CHICK (Q5ZK84), AK1A1_CRIGR (O70473), 
AK1A1_HUMAN (P14550), AK1A1_MOUSE (Q9JII6), AK1A1_PIG   (P50578), 
AK1A1_PONAB (Q5R5D5), AK1A1_RAT   (P51635), AK1A1_XENLA (Q6GMC7), 
AK1A1_XENTR (Q28FD1), AK1BA_HUMAN (O60218), AK1C1_HUMAN (Q04828), 
AK1C1_MACFA (Q95JH7), AK1C1_MACFU (Q95JH6), AK1C1_PONAB (Q5REQ0), 
AK1C3_HUMAN (P42330), AK1C3_PONAB (Q5R7C9), AK1C4_HUMAN (P17516), 
AK1C4_MACFA (Q95JH5), AK1C4_MACFU (Q95JH4), AK1CD_MESAU (P82809), 
AK1CD_MOUSE (Q8VC28), AK1CN_HORSE (Q1XAA8), AK1CO_HORSE (Q6W8P9), 
AK1D1_HUMAN (P51857), AK1D1_MOUSE (Q8VCX1), AK1D1_RABIT (Q9TV64), 
AK1D1_RAT   (P31210), AKC1H_RAT   (P51652), AKCL1_HUMAN (Q5T2L2), 
AKCL2_HUMAN (Q96JD6), AKCL2_MOUSE (Q9DCT1), AKCL2_PIG   (P82125), 
AKCL2_RAT   (Q5U1Y4), AKRC8_ARATH (O80944), AKRC9_ARATH (Q0PGJ6), 
AKRCA_ARATH (Q84TF0), ALD1_MOUSE  (P21300), ALD1_RAT    (Q5RJP0), 
ALD2_CRIGR  (O08782), ALD2_MOUSE  (P45377), ALDR_BOVIN  (P16116), 
ALDR_ENCCU  (Q8SSK6), ALDR_HORVU  (P23901), ALDR_HUMAN  (P15121), 
ALDR_MOUSE  (P45376), ALDR_PIG    (P80276), ALDR_RABIT  (P15122), 
ALDR_RAT    (P07943), ALDX_SPOSA  (P27800), ALRA_DICDI  (Q6IMN8), 
ALRB_DICDI  (Q54NZ7), ALRC_DICDI  (Q55FL3), ARA1_YEAST  (P38115), 
COR11_PAPSO (Q9SQ70), COR12_PAPSO (Q9SQ69), COR13_PAPSO (Q9SQ68), 
COR14_PAPSO (Q9SQ67), COR15_PAPSO (B9VRJ2), COR2_PAPSO  (Q9SQ64), 
CRO_LITCT   (P17264), CRO_RANTE   (P02532), DDBX_BOVIN  (P52898), 
DHB5_MOUSE  (P70694), DIDH_RAT    (P23457), DKGA_CORSC  (P06632), 
DKGA_ECO57  (Q8XBT6), DKGA_ECOLI  (Q46857), DKGA_SALTI  (P58744), 
DKGA_SALTY  (Q8ZM06), DKGA_YERPE  (Q8ZI40), DKGB_CORSS  (P15339), 
DKGB_ECO57  (Q8X7Z7), DKGB_ECOLI  (P30863), DKGB_SALTI  (Q8Z988), 
DKGB_SALTY  (Q8ZRM7), DKGB_YERPE  (Q8ZH36), DTDH_MUCMU  (Q01213), 
GCY_YEAST   (P14065), GRE3_YEAST  (P38715), GR_BACSU    (O32210), 
MER_ERYCB   (E7C196), MORA_PSEPU  (Q02198), NADO1_ORYSJ (Q7G764), 
NADO2_ORYSJ (Q7G765), PE2R_RABIT  (P80508), PGFS1_BOVIN (P05980), 
PGFS2_BOVIN (P52897), PGFS_LEIMA  (P22045), PGFS_TRYBB  (Q9GV41), 
PGFS_TRYCC  (Q4DJ07), S6PD_MALDO  (P28475), XYL1_ARTOC  (C5FFQ7), 
XYL1_ASPCL  (A1CRI1), XYL1_ASPFC  (B0XNR0), XYL1_ASPFN  (B8N195), 
XYL1_ASPFU  (Q4WJT9), XYL1_ASPNC  (A2Q8B5), XYL1_ASPNG  (Q9P8R5), 
XYL1_ASPOR  (Q2UKD0), XYL1_ASPTN  (Q0CUL0), XYL1_CANBO  (Q8X195), 
XYL1_CANPA  (Q6Y0Z3), XYL1_CANTE  (O74237), XYL1_CANTR  (O13283), 
XYL1_EMENI  (Q5BGA7), XYL1_HYPJE  (Q876L8), XYL1_KLULA  (P49378), 
XYL1_NEOFI  (A1D4E3), XYL1_PACTA  (P78736), XYL1_PICGU  (O94735), 
XYL1_PICST  (P31867), XYL1_SCHSH  (Q9P430), XYL2_CANTR  (P87039), 
Y1918_MYCSJ (A3PXS9), Y1938_MYCSS (Q1BAN7), Y1984_MYCSK (A1UEC5), 
Y2161_MYCVP (A1T726), Y2407_MYCS2 (A0QV09), Y4205_MYCGI (A4TE41), 
YBN4_SCHPO  (O42888), YDG7_SCHPO  (Q10494), YER5_SCHPO  (O14088), 
YJ66_YEAST  (P47137), YKW2_SCHPO  (Q9C1X5), YOF5_CAEEL  (Q09632), 
YPR1_YEAST  (Q12458), YTBE_BACSU  (O34678)
False negative hits (sequences which belong to the set under consideration, but which have not been picked up by the pattern or profile):
AK1BF_HUMAN (C9JRZ8), AK1C2_HUMAN (P52895), AK1CL_MOUSE (Q91WR5), 
AK1CL_RAT   (Q6AYQ2), AKCL2_MACFA (Q4R802), AKR1_ARATH  (Q9C5B9), 
AKR1_ORYSI  (B8ASB2), AKR1_ORYSJ  (Q0JE32), AKR1_SOYBN  (C6TBN2), 
AKR2_ORYSI  (A2XRZ0), AKR2_ORYSJ  (Q7XT99), AKR3_ORYSI  (A2XRZ6), 
AKR3_ORYSJ  (Q7XQ45), AKR6_ARATH  (F4HPY8), ALKR2_ARATH (Q84M96), 
ALKR3_ARATH (O22707), ALKR4_ARATH (Q93ZN2), ALKR5_ARATH (Q9ASZ9), 
ARA2_YEAST  (Q04212), FCDH_PSESP  (Q52472), GALDH_ARATH (O81884), 
I3ACR_SCHPO (O13848), KAR_YEAST   (Q07551), PERR_RAUSE  (Q3L181), 
PLR1_SCHPO  (O14295), PLR1_YEAST  (Q06494), PLR2_SCHPO  (O94521), 
Y1669_MYCLB (B8ZS00), Y1669_MYCLE (O69462), Y1744_MYCMM (B2HIJ9), 
Y1919_MYCSJ (A3PXT0), Y1985_MYCSK (A1UEC6), Y1987_MYCUA (A0PQ11), 
Y2408_MYCS2 (A0QV10), Y2971_MYCTU (P95124), Y2993_MYCBP (A1KMW6), 
Y2996_MYCBO (Q7TXI6), Y2999_MYCTA (A5U6Y1), Y3007_MYCPA (Q73VK6), 
Y3816_MYCA1 (A0QJ99), Y4149_MYCPA (Q73SC5), Y4483_MYCA1 (A0QL30), 
YEZB_SCHPO  (O14125), YH5B_SCHPO  (O94315)
`Potential' hits (partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences):
CROB_LEPLU  (P49261), DHGP_ASPNG  (P55804), MORA_RABIT  (P82810)
Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:

[Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format]

Retrieve the sequence logo from the alignment

PDB
[Detailed view]
1A80; 1ABN; 1ADS; 1AE4; 1AFS; 1AH0; 1AH3; 1AH4; 1AZ1; 1AZ2; 1C9W; 1CWN; 1DLA; 1EF3; 1EKO; 1EL3; 1FRB; 1HQT; 1HW6; 1IEI; 1JEZ; 1K8C; 1LLG; 1LWI; 1M9H; 1MAR; 1MI3; 1MRQ; 1MZR; 1PWL; 1PWM; 1Q13; 1Q5M; 1R38; 1RAL; 1RY0; 1RY8; 1S1P; 1S1R; 1S2A; 1S2C; 1SM9; 1T40; 1T41; 1US0; 1VBJ; 1X96; 1X97; 1X98; 1XF0; 1XGD; 1YE4; 1YE6; 1Z3N; 1Z89; 1Z8A; 1Z9A; 1ZQ5; 1ZUA; 2ACQ; 2ACR; 2ACS; 2ACU; 2AGT; 2ALR; 2AR4; 2BGQ; 2BGS; 2DUX; 2DUZ; 2DV0; 2F2K; 2F38; 2FGB; 2FVL; 2FZ8; 2FZ9; 2FZB; 2FZD; 2GO6; 2HV5; 2HVN; 2HVO; 2I16; 2I17; 2IKG; 2IKH; 2IKI; 2IKJ; 2INE; 2INZ; 2IPW; 2IQ0; 2IQD; 2IS7; 2ISF; 2J8T; 2NVC; 2NVD; 2PD5; 2PD9; 2PDB; 2PDC; 2PDF; 2PDG; 2PDH; 2PDI; 2PDJ; 2PDK; 2PDL; 2PDM; 2PDN; 2PDP; 2PDQ; 2PDU; 2PDW; 2PDX; 2PDY; 2PEV; 2PF8; 2PFH; 2PZN; 2QXW; 2R24; 2VDG; 2WZM; 2WZT; 3B3D; 3BCJ; 3BUR; 3BUV; 3BV7; 3C3U; 3CAQ; 3CAS; 3CAV; 3CMF; 3COT; 3CV7; 3D3F; 3DN5; 3DOP; 3F7J; 3FX4; 3G1R; 3G5E; 3GHR; 3GHS; 3GHT; 3GHU; 3GUG; 3H4G; 3H7R; 3H7U; 3LBO; 3LD5; 3LEN; 3LEP; 3LN3; 3LQG; 3LQL; 3LZ3; 3LZ5; 3M0I; 3M4H; 3M64; 3MB9; 3MC5; 3NTY; 3O3R; 3ONB; 3ONC; 3P2V; 3Q65; 3Q67; 3QKZ; 3R43; 3R58; 3R6I; 3R7M; 3R8G; 3R8H; 3R94; 3RX2; 3RX3; 3RX4; 3S3G; 3T42; 3U2C; 3UFY; 3UG8; 3UGR; 3UWE; 3UZW; 3UZX; 3UZY; 3UZZ; 3V35; 3V36; 3V9Q; 4DBS; 4DBU; 4DBW; 4DZ5; 4F40; 4FA3; 4FAL; 4FAM; 4FZI; 4G5D; 4GAC; 4GIE;

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