PROSITE logo

PROSITE entry PS00888


View entry in original PROSITE format
View entry in raw text format (no links)
View entry auxiliary file in raw text format (no links)
Direct ScanProsite submission
General information about the entry

Entry name [info] CNMP_BINDING_1
Accession [info] PS00888
Entry type [info] PATTERN
Date [info] 01-OCT-1993 CREATED;
01-DEC-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00691

Name and characterization of the entry

Description [info] Cyclic nucleotide-binding domain signature 1.
Pattern [info]
[LIVM]-[VIC]-x-{H}-G-[DENQTA]-x-[GAC]-{L}-x-[LIVMFY](4)-x(2)-G.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_05 which contains 572'214 sequence entries.


Total number of hits 188 in 130 different sequences
Number of true positive hits 177 in 119 different sequences
Number of 'unknown' hits 0
Number of false positive hits 11 in 11 different sequences
Number of false negative sequences 190
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 94.15 %
Recall (true positives / (true positives + false negatives)) 48.23 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 3
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
119 sequences

CNBD2_HUMAN (Q96M20), CNBD2_MACFA (Q95JR6), CNBD2_MOUSE (Q9D5U8), 
CNG1_CHICK  (Q90805), CNG3_CHICK  (Q90980), CNGA1_BOVIN (Q00194), 
CNGA1_CANLF (Q28279), CNGA1_HUMAN (P29973), CNGA1_MOUSE (P29974), 
CNGA1_RAT   (Q62927), CNGA2_BOVIN (Q03041), CNGA2_HUMAN (Q16280), 
CNGA2_MOUSE (Q62398), CNGA2_RABIT (Q28718), CNGA2_RAT   (Q00195), 
CNGA3_BOVIN (Q29441), CNGA3_HUMAN (Q16281), CNGA3_MOUSE (Q9JJZ8), 
CNGA3_RAT   (Q9ER33), CNGA4_HUMAN (Q8IV77), CNGA4_MOUSE (Q3UW12), 
CNGA4_RAT   (Q64359), CNGA_DROME  (Q24278), CNGB1_BOVIN (Q28181), 
CNGB1_HUMAN (Q14028), CNGB1_MOUSE (E1AZ71), CNGB1_RAT   (A0A8I5ZN27), 
CNGB3_CANLF (Q8MJD7), CNGB3_HUMAN (Q9NQW8), CNGB3_MOUSE (Q9JJZ9), 
CNGK1_RHIEC (Q2K5E1), CNGK1_RHILO (Q98GN8), CNG_CAEEL   (Q03611), 
CNG_ICTPU   (P55934), CRP_ECO57   (P0ACK0), CRP_ECOL6   (P0ACJ9), 
CRP_ECOLI   (P0ACJ8), CRP_HAEIN   (P29281), CRP_KLEAE   (P0A2T7), 
CRP_PASMU   (O05689), CRP_SALTY   (P0A2T6), CRP_SHIFL   (P0ACK1), 
EGL4_CAEBR  (A8X6H1), EGL4_CAEEL  (O76360), GLSA2_BRADU (Q89KV2), 
HCN1_HUMAN  (O60741), HCN1_MOUSE  (O88704), HCN1_RABIT  (Q9MZS1), 
HCN1_RAT(Q9JKB0), HCN2_HUMAN  (Q9UL51), HCN2_MOUSE  (O88703), 
HCN2_RAT(Q9JKA9), HCN4_HUMAN  (Q9Y3Q4), HCN4_MOUSE  (O70507), 
HCN4_RABIT  (Q9TV66), HCN4_RAT(Q9JKA7), KAP0_BOVIN  (P00514), 
KAP0_CHICK  (Q5ZM91), KAP0_DANRE  (Q5I0F6), KAP0_HUMAN  (P10644), 
KAP0_MESAU  (P86244), KAP0_MOUSE  (Q9DBC7), KAP0_PIG(P07802), 
KAP0_PONAB  (Q5REL1), KAP0_RAT(P09456), KAP1_HUMAN  (P31321), 
KAP1_MOUSE  (P12849), KAP1_RAT(P81377), KAP2_BOVIN  (P00515), 
KAP2_HUMAN  (P13861), KAP2_MOUSE  (P12367), KAP2_RAT(P12368), 
KAP3_BOVIN  (P31322), KAP3_HUMAN  (P31323), KAP3_MOUSE  (P31324), 
KAP3_RAT(P12369), KAPR1_DROME (P16905), KAPR2_DROME (P81900), 
KAPR_APLCA  (P31319), KAPR_ASPFU  (Q96UX3), KAPR_ASPNG  (Q9C196), 
KAPR_BLAEM  (P31320), KAPR_BLUGR  (Q9HEP7), KAPR_CAEEL  (P30625), 
KAPR_CANAL  (Q9HEW1), KAPR_CANGA  (Q6FQL6), KAPR_COLOR  (Q9C1C2), 
KAPR_COLTR  (O42794), KAPR_DEBHA  (Q6BZG7), KAPR_DICDI  (P05987), 
KAPR_EMENI  (O59922), KAPR_EREGS  (Q75AM2), KAPR_HYPAT  (Q86ZN7), 
KAPR_KLULA  (Q6CPK7), KAPR_MUCCL  (Q8TF77), KAPR_NEUCR  (Q01386), 
KAPR_PYRO7  (O14448), KAPR_SCHPO  (P36600), KAPR_STRPU  (Q26619), 
KAPR_USTMA  (P49605), KAPR_YARLI  (Q6C2X0), KAPR_YEAST  (P07278), 
KGP1_BOVIN  (P00516), KGP1_DROME  (Q03042), KGP1_HUMAN  (Q13976), 
KGP1_MOUSE  (P0C605), KGP24_DROME (Q03043), KGP25_DROME (P32023), 
KGP2_HUMAN  (Q13237), KGP2_MOUSE  (Q61410), KGP2_RAT(Q64595), 
KGP_EIMTE   (Q8MMZ8), KGP_PLABA   (A0A509AKL0), KGP_PLAF7   (Q8I719), 
KGP_PLAFO   (W7JX98), KGP_PLAVS   (A5K0N4), KGP_TOXGO   (Q8MMZ7), 
NTE1_SCHPO  (Q9USJ4), VFR_PSEAE   (P55222)
» more

UniProtKB/Swiss-Prot
False negative sequences
190 sequences

ACH1_ARATH  (Q5FYU1), AKT1_ARATH  (Q38998), AKT1_ORYSI  (P0C550), 
AKT1_ORYSJ  (Q0JKV1), AKT2_ARATH  (Q38898), AKT2_ORYSJ  (Q75HP9), 
AKT3_ORYSJ  (Q8H569), AKT5_ARATH  (Q9SCX5), AKT6_ARATH  (Q8GXE6), 
ANR_PSEPH   (O85222), ARCR_STAA1  (A7X715), ARCR_STAA2  (A6U515), 
ARCR_STAA3  (Q2FDM8), ARCR_STAA8  (Q2FUY1), ARCR_STAA9  (A5IW58), 
ARCR_STAAB  (Q2YWH5), ARCR_STAAC  (Q5HCR6), ARCR_STAAE  (A6QKC0), 
ARCR_STAAM  (Q99R06), ARCR_STAAN  (Q7A381), ARCR_STAAR  (Q6GDH1), 
ARCR_STAAS  (Q6G643), ARCR_STAAT  (A8Z5D0), ARCR_STAAW  (Q8NUK9), 
ARCR_STAEQ  (Q5HKU6), ARCR_STAES  (Q8CML2), ARCR_STAHJ  (Q4L9J7), 
CLP_XANAC   (Q8PQ45), CLP_XANC8   (Q4UZF6), CLP_XANCB   (B0RN01), 
CLP_XANCP   (P22260), CLP_XANE5   (Q3BYB3), CLP_XANOM   (Q2NYD9), 
CLP_XANOP   (B2SL05), CLP_XANOR   (Q5GV61), CMR_MYCTO   (P9WMH4), 
CMR_MYCTU   (P9WMH5), CN15A_MEDTR (G7IBJ4), CN15B_MEDTR (G7JND3), 
CN15C_MEDTR (A0A072VMJ3), CNBD1_HUMAN (Q8NA66), CNG10_ARATH (Q9LNJ0), 
CNG11_ARATH (Q9SKD6), CNG12_ARATH (Q8GWD2), CNG13_ARATH (Q9LD40), 
CNG14_ARATH (Q9SJA4), CNG15_ARATH (Q9SL29), CNG16_ARATH (Q9SU64), 
CNG17_ARATH (Q8L7Z0), CNG18_ARATH (Q9LEQ3), CNG19_ARATH (Q9LDR2), 
CNG20_ARATH (Q9LD37), CNGC1_ARATH (O65717), CNGC2_ARATH (O65718), 
CNGC3_ARATH (Q9SKD7), CNGC4_ARATH (Q94AS9), CNGC5_ARATH (Q8RWS9), 
CNGC6_ARATH (O82226), CNGC7_ARATH (Q9S9N5), CNGC8_ARATH (Q9FXH6), 
CNGC9_ARATH (Q9M0A4), CRPL_CORGL  (Q79VI7), CRPL_MYCTO  (P9WMH2), 
CRPL_MYCTU  (P9WMH3), GBPC_DICDI  (Q8MVR1), GBPD_DICDI  (Q54S40), 
GORK_ARATH  (Q94A76), HCN3_HUMAN  (Q9P1Z3), HCN3_MOUSE  (O88705), 
HCN3_RAT(Q9JKA8), KAT1_ARATH  (Q39128), KAT1_ORYSJ  (Q6K3T2), 
KAT2_ARATH  (Q38849), KAT2_ORYSJ  (Q5QNI1), KAT3_ARATH  (P92960), 
KAT3_ORYSJ  (Q5JM04), KAT4_ORYSJ  (Q652U9), KAT5_ORYSJ  (Q7XT08), 
KAT6_ORYSJ  (A2ZX97), KCNAE_DROME (Q02280), KCNH1_BOVIN (O18965), 
KCNH1_HUMAN (O95259), KCNH1_MOUSE (Q60603), KCNH1_RAT   (Q63472), 
KCNH2_CANLF (Q9TSZ3), KCNH2_CAVPO (O08703), KCNH2_HUMAN (Q12809), 
KCNH2_MOUSE (O35219), KCNH2_PIG   (Q9TUI4), KCNH2_RABIT (Q8WNY2), 
KCNH2_RAT   (O08962), KCNH3_HUMAN (Q9ULD8), KCNH3_MOUSE (Q9WVJ0), 
KCNH3_RAT   (O89047), KCNH4_HUMAN (Q9UQ05), KCNH4_RAT   (Q9R1T9), 
KCNH5_HUMAN (Q8NCM2), KCNH5_MOUSE (Q920E3), KCNH5_RAT   (Q9EPI9), 
KCNH6_CHICK (Q9PT84), KCNH6_HUMAN (Q9H252), KCNH6_RAT   (O54853), 
KCNH7_HUMAN (Q9NS40), KCNH7_MOUSE (Q9ER47), KCNH7_RAT   (O54852), 
KCNH8_HUMAN (Q96L42), KCNH8_MOUSE (P59111), KCNH8_RAT   (Q9QWS8), 
KGP1_RABIT  (O77676), KOR1_ORYSJ  (Q653P0), KOR2_ORYSJ  (Q7XUW4), 
LDRP_THET2  (Q746J8), LDRP_THET8  (Q53W63), NTE1_ASPCL  (A1C9L6), 
NTE1_ASPFU  (Q4WA15), NTE1_ASPNC  (A2R350), NTE1_ASPOR  (Q2UDH2), 
NTE1_ASPTN  (Q0CNC7), NTE1_CANAL  (Q5A368), NTE1_CANGA  (Q6FKJ1), 
NTE1_CHAGB  (Q2H0D3), NTE1_COCIM  (Q1DLC7), NTE1_CRYNB  (P0CP37), 
NTE1_CRYNJ  (P0CP36), NTE1_DEBHA  (Q6BQK9), NTE1_EMENI  (Q5BAE9), 
NTE1_EREGS  (Q756Z0), NTE1_KLULA  (Q6CWC2), NTE1_LODEL  (A5E708), 
NTE1_NEOFI  (A1D9Y2), NTE1_NEUCR  (Q7S8J1), NTE1_PHANO  (Q0UJ42), 
NTE1_PICGU  (A5DHA3), NTE1_PICST  (A3LYZ4), NTE1_PYRO7  (A4QVZ8), 
NTE1_USTMA  (Q4PF83), NTE1_YARLI  (Q6CF18), NTE1_YEAST  (Q04958), 
P2C19_ARATH (Q9SL76), PAT_MYCS2   (A0R3F9), PAT_MYCTU   (O05581), 
PCTIR_BURCE (A0A0J5WTU0), PCTIR_PSEAI (P0DV41), PCTIR_RHOS2 (A0A1V0HUU2), 
PCTIR_XANPE (P0DV29), PDE5_DICDI  (Q8MLZ3), PDE6_DICDI  (Q8MM62), 
PLPL6_CAEEL (Q21534), PLPL6_HUMAN (Q8IY17), PLPL6_MOUSE (Q3TRM4), 
PLPL6_PONAB (Q5RDS0), PLPL7_CAEEL (Q02331), PLPL7_HUMAN (Q6ZV29), 
PLPL7_MOUSE (A2AJ88), PLPL7_RAT   (Q5BK26), RPGF1_CAEEL (P34578), 
RPGF2_BOVIN (F1MSG6), RPGF2_CANLF (F1PBJ0), RPGF2_HUMAN (Q9Y4G8), 
RPGF2_MOUSE (Q8CHG7), RPGF2_RAT   (F1M386), RPGF3_HUMAN (O95398), 
RPGF3_MOUSE (Q8VCC8), RPGF3_RAT   (Q9Z1C8), RPGF4_HUMAN (Q8WZA2), 
RPGF4_MOUSE (Q9EQZ6), RPGF_CAEEL  (G5EDB9), SDRP_THET8  (Q5SIL0), 
SKOR_ARATH  (Q9M8S6), SL9C1_HUMAN (Q4G0N8), SL9C1_MOUSE (Q6UJY2), 
SL9C2_HUMAN (Q5TAH2), SWS_DROAN   (B3MRI9), SWS_DROER   (B3NY03), 
SWS_DROGR   (B4JLX2), SWS_DROME   (Q9U969), SWS_DROMO   (B4L535), 
SWS_DROPE   (B4H3U8), SWS_DROPS   (B5DKS8), SWS_DROSE   (B4IL64), 
SWS_DROVI   (B4M709), SWS_DROWI   (B4N1W9), SWS_DROYA   (B4Q0P3), 
UEX_DROME   (A0A0B7P9G0), Y073_MYCTO  (P9WQK4), Y073_MYCTU  (P9WQK5), 
Y2565_MYCTO (P9WIY6), Y2565_MYCTU (P9WIY7), Y2594_MYCBO (P0A643), 
Y4233_RHOPA (Q02006)
» more

UniProtKB/Swiss-Prot
'Partial' sequences
1 sequence

KAP2_PIG(P05207)

		
UniProtKB/Swiss-Prot
False positive sequences
11 sequences

ALG11_HUMAN (Q2TAA5), ALG11_PONAB (Q5R7Z6), CARA_SULTO  (Q970U8), 
CBIMQ_METLZ (A2SSD6), DAPB_PYRO7  (A4QYQ5), DESA_PICP2  (Q55231), 
EPHA_MYCTU  (I6YGS0), SFSA_GEOMG  (Q39WK9), SFSA_GEOSL  (P61664), 
SFSA_TRIEI  (Q111B4), SYT15_HUMAN (Q9BQS2)
» more

PDB
[Detailed view]
210 PDB

1CGP; 1CX4; 1G6N; 1HW5; 1I5Z; 1I6X; 1J59; 1LB2; 1NE4; 1NE6; 1O3Q; 1O3R; 1O3S; 1O3T; 1Q3E; 1Q43; 1Q5O; 1RGS; 1RL3; 1RUN; 1RUO; 1U12; 1VP6; 1ZRC; 1ZRD; 1ZRE; 1ZRF; 2CGP; 2GZW; 2K0G; 2KXL; 2MNG; 2MPF; 2OZ6; 2Q0A; 2QCS; 2QVS; 2WC2; 2ZD9; 3BEH; 3BPZ; 3CL1; 3CLP; 3CO2; 3ETQ; 3FFQ; 3FHI; 3FWE; 3HIF; 3IDB; 3IDC; 3IIA; 3IYD; 3J4Q; 3J4R; 3KCC; 3N4M; 3OCP; 3OD0; 3OF1; 3OGJ; 3OTF; 3PLQ; 3PNA; 3PVB; 3QOP; 3RDI; 3ROU; 3RPQ; 3RYP; 3RYR; 3SHR; 3TNP; 3TNQ; 3U0Z; 3U10; 3U11; 4BH9; 4BHP; 4CHV; 4CHW; 4DIN; 4FT8; 4HBN; 4HZF; 4I01; 4I02; 4I09; 4I0A; 4I0B; 4JV4; 4JVA; 4KL1; 4KU7; 4KU8; 4MUV; 4MX3; 4NVP; 4OFF; 4OFG; 4QX5; 4QXK; 4R8H; 4RZ7; 4WBB; 4X6Q; 4X6R; 4Z07; 5BV6; 5C6C; 5C8W; 5CIZ; 5DYK; 5DYL; 5DZC; 5E16; 5EZR; 5F0A; 5FET; 5H3O; 5J48; 5JAX; 5JD7; 5JIX; 5JIZ; 5JON; 5JR7; 5KHG; 5KHH; 5KHI; 5KHJ; 5KHK; 5KJX; 5KJY; 5KJZ; 5L0N; 5U6O; 5U6P; 6B6H; 6BQ8; 6BYR; 6BYS; 6EO1; 6GYN; 6GYO; 6I9D; 6IAX; 6M63; 6NO7; 6PB4; 6PB5; 6PB6; 6QCY; 6QCZ; 6QD0; 6QD1; 6QD2; 6QD3; 6QD4; 6UQF; 6UQG; 6WEJ; 6WEK; 6WEL; 6WJF; 6WJG; 7FEW; 7FF0; 7FF8; 7FF9; 7LFT; 7LFW; 7LFX; 7LFY; 7LG1; 7LV3; 7LZ4; 7MBJ; 7N15; 7N16; 7N17; 7NMN; 7NP3; 7NP4; 7O4H; 7RH9; 7RHG; 7RHH; 7RHI; 7RHJ; 7RHK; 7RHL; 7RHS; 7SSB; 7T4T; 7T4U; 7T4V; 7T4W; 8BX7; 8EM8; 8ETP; 8EU3; 8EUC; 8EV8; 8EV9; 8EVA; 8EVB; 8EVC; 8T4M; 8T4Y
» more