Entry: PS00915

General information about the entry
Entry name PI3_4_KINASE_1
Accession number PS00915
Entry type PATTERN
Date OCT-1993 (CREATED); DEC-2004 (DATA UPDATE); APR-2013 (INFO UPDATE).
PROSITE Documentation PDOC00710
Name and characterization of the entry
DescriptionPhosphatidylinositol 3- and 4-kinases signature 1.
Pattern [LIVMFAC]-K-x(1,3)-[DEA]-[DE]-[LIVMCP]-R-Q-[DE]-x(4)-Q.
Numerical results
  • UniProtKB/Swiss-Prot release number: 2013_06, total number of sequence entries in that release: 540261.
  • Total number of hits in UniProtKB/Swiss-Prot: 98 hits in 98 different sequences
  • Number of hits on proteins that are known to belong to the set under consideration: 98 hits in 98 different sequences
  • Number of hits on proteins that could potentially belong to the set under consideration: 0 hits in 0 different sequences
  • Number of false hits (on unrelated proteins): 0 hits in 0 different sequences
  • Number of known missed hits: 50
  • Number of partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences: 0
  • Precision (true hits / (true hits + false positives)): 100.00 %
  • Recall (true hits / (true hits + false negatives)): 66.22 %
Comments
  • Taxonomic range: Eukaryotes, Eukaryotic viruses
  • Maximum known number of repetitions of the pattern in a single protein: 1
  • VERSION: 1
Cross-references
UniProtKB/Swiss-Prot True positive hits:
AGE1_CAEBR  (P0C5E7), AGE1_CAEEL  (Q94125), ATM_ARATH   (Q9M3G7), 
ATM_ASHGO   (Q751J3), ATM_ASPFU   (Q4WVM7), ATM_ASPOR   (Q2U639), 
ATM_CANGA   (Q6FRZ9), ATM_DEBHA   (Q6BV76), ATM_DROME   (Q5EAK6), 
ATM_EMENI   (Q5BHE2), ATM_GIBZE   (Q4IB89), ATM_HUMAN   (Q13315), 
ATM_KLULA   (Q6CP76), ATM_MOUSE   (Q62388), ATM_NEUCR   (Q7RZT9), 
ATM_PIG     (Q6PQD5), ATM_SCHPO   (O74630), ATM_YARLI   (Q6CAD2), 
ATM_YEAST   (P38110), ATR_ASHGO   (Q75DB8), ATR_CANGA   (Q6FX42), 
ATR_KLULA   (Q6CT34), ATR_YEAST   (P38111), MTOR_HUMAN  (P42345), 
MTOR_MOUSE  (Q9JLN9), MTOR_RAT    (P42346), P3C2A_HUMAN (O00443), 
P3C2A_MOUSE (Q61194), P3C2A_PONAB (Q5RAY1), P3C2B_HUMAN (O00750), 
P3C2G_HUMAN (O75747), P3C2G_MOUSE (O70167), P3C2G_RAT   (O70173), 
P4KA1_ARATH (Q9SXA1), P4KA2_ARATH (Q9C680), P4KB1_ARATH (Q9FMJ0), 
P4KB2_ARATH (Q0WPX9), PI3K1_DICDI (P54673), PI3K1_SOYBN (P42347), 
PI3K2_DICDI (P54674), PI3K2_SOYBN (P42348), PI3K3_DICDI (P54675), 
PI3K4_DICDI (P54676), PI3K_ARATH  (P42339), PI4KA_BOVIN (O02811), 
PI4KA_HUMAN (P42356), PI4KB_BOVIN (O02810), PI4KB_CALJA (B0KWC1), 
PI4KB_CALMO (B1MTG7), PI4KB_DANRE (Q49GP3), PI4KB_HUMAN (Q9UBF8), 
PI4KB_MOUSE (Q8BKC8), PI4KB_OTOGA (B4UT09), PI4KB_PAPAN (A9X1A0), 
PI4KB_RAT   (O08561), PI4KB_RHIFE (B2KI64), PI4KB_SORAR (B3EX61), 
PI4KB_XENLA (Q6GN16), PI4KB_XENTR (A4IID4), PI4K_DICDI  (P54677), 
PIK1_SCHPO  (Q10366), PIK1_YEAST  (P39104), PK3C3_HUMAN (Q8NEB9), 
PK3C3_MOUSE (Q6PF93), PK3C3_PIG   (Q5D891), PK3C3_RAT   (O88763), 
PK3C3_XENLA (Q6AZN6), PK3CA_BOVIN (P32871), PK3CA_HUMAN (P42336), 
PK3CA_MOUSE (P42337), PK3CB_HUMAN (P42338), PK3CB_MOUSE (Q8BTI9), 
PK3CB_RAT   (Q9Z1L0), PK3CD_HUMAN (O00329), PK3CD_MOUSE (O35904), 
PK3CG_HUMAN (P48736), PK3CG_MOUSE (Q9JHG7), PK3CG_PIG   (O02697), 
PRKDC_CANFA (Q8WN22), PRKDC_CHICK (Q8QGX4), PRKDC_HUMAN (P78527), 
PRKDC_MOUSE (P97313), PRKDC_XENLA (Q9DEI1), STT4_ENCCU  (Q8SQY7), 
STT4_SCHPO  (Q9USR3), STT4_YEAST  (P37297), TOR1_SCHPO  (O14356), 
TOR1_YEAST  (P35169), TOR2_SCHPO  (Q9Y7K2), TOR2_YEAST  (P32600), 
TOR_ARATH   (Q9FR53), TOR_CAEEL   (Q95Q95), TOR_DICDI   (Q86C65), 
TOR_DROME   (Q9VK45), TOR_ORYSJ   (Q0DJS1), VPS34_CANAX (Q92213), 
VPS34_SCHPO (P50520), VPS34_YEAST (P22543)
False negative hits (sequences which belong to the set under consideration, but which have not been picked up by the pattern or profile):
ATM_CAEEL   (Q9N3Q4), ATM_CANAL   (Q5ABX0), ATM_CRYNB   (P0CP61), 
ATM_CRYNJ   (P0CP60), ATR1_DICDI  (Q54ER4), ATR_ARATH   (Q9FKS4), 
ATR_CAEEL   (Q22258), ATR_CANAL   (Q59LR2), ATR_DROME   (Q9VXG8), 
ATR_ENCCU   (Q8SSE7), ATR_HUMAN   (Q13535), ATR_MOUSE   (Q9JKK8), 
ATR_ORYSI   (A2YH41), ATR_ORYSJ   (Q5Z987), ATR_XENLA   (Q9DE14), 
LSB6_SCHPO  (Q9UT42), LSB6_YEAST  (P42951), P4K2A_DANRE (Q6PE18), 
P4K2A_HUMAN (Q9BTU6), P4K2A_MOUSE (Q2TBE6), P4K2A_RAT   (Q99M64), 
P4K2A_XENLA (Q08B31), P4K2A_XENTR (Q505I0), P4K2B_ARATH (Q9C671), 
P4K2B_CHICK (Q5ZIK0), P4K2B_DANRE (Q49GP5), P4K2B_HUMAN (Q8TCG2), 
P4K2B_MOUSE (Q8CBQ5), P4K2B_RAT   (Q5XIL2), P4K2B_XENLA (Q6DCQ8), 
P4K2B_XENTR (Q28G26), PI4P2_HUMAN (A4QPH2), PIK1A_CANAL (Q9UW24), 
PIK1_CANAL  (Q9UW20), PRKDC_DICDI (Q54UC0), RAD3_SCHPO  (Q02099), 
SMG1_CAEBR  (Q61CW2), SMG1_CAEEL  (O01510), SMG1_DICDI  (Q553E9), 
SMG1_DROME  (Q70PP2), SMG1_HUMAN  (Q96Q15), SMG1_MOUSE  (Q8BKX6), 
TRA1_DROME  (Q8I8U7), TRA1_SCHPO  (Q9HFE8), TRA1_YEAST  (P38811), 
TRRAP_HUMAN (Q9Y4A5), TRRAP_MOUSE (Q80YV3), VPS34_ENCCU (Q8SR56), 
YAMB_SCHPO  (Q10064), YL615_MIMIV (Q5UR69)
Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:

[Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format]

Retrieve the sequence logo from the alignment

PDB
[Detailed view]
1E7U; 1E7V; 1E8W; 1E8X; 1E8Y; 1E8Z; 1E90; 1HE8; 2A4Z; 2A5U; 2CHW; 2CHX; 2CHZ; 2RD0; 2V4L; 2WXF; 2WXG; 2WXH; 2WXI; 2WXJ; 2WXK; 2WXL; 2WXM; 2WXN; 2WXO; 2WXP; 2WXQ; 2WXR; 2X38; 2Y3A; 3APC; 3APD; 3APF; 3CSF; 3CST; 3DBS; 3DPD; 3ENE; 3HHM; 3HIZ; 3IBE; 3IHY; 3L08; 3L13; 3L16; 3L17; 3L54; 3LJ3; 3LS8; 3MJW; 3ML8; 3ML9; 3NZS; 3NZU; 3OAW; 3P2B; 3PRE; 3PRZ; 3PS6; 3QAQ; 3QAR; 3QJZ; 3QK0; 3R7Q; 3R7R; 3S2A; 3SD5; 3T8M; 3TJP; 3TL5; 3ZIM; 3ZVV; 3ZW3; 4A55; 4AJW; 4ANU; 4ANV; 4ANW; 4ANX; 4AOF; 4DK5; 4F1S; 4FA6; 4FAD; 4FHJ; 4FHK; 4FJY; 4FJZ; 4FLH; 4FUL; 4G11; 4GB9; 4HLE;

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