PROSITE logo

PROSITE entry PS00915


View entry in original PROSITE format
View entry in raw text format (no links)
View entry auxiliary file in raw text format (no links)
Direct ScanProsite submission
General information about the entry

Entry name [info] PI3_4_KINASE_1
Accession [info] PS00915
Entry type [info] PATTERN
Date [info] 01-OCT-1993 CREATED;
01-DEC-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00710

Name and characterization of the entry

Description [info] Phosphatidylinositol 3- and 4-kinases signature 1.
Pattern [info]
[LIVMFAC]-K-x(1,3)-[DEA]-[DE]-[LIVMCP]-R-Q-[DE]-x(4)-Q.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_06 which contains 572'619 sequence entries.


Total number of hits 103 in 103 different sequences
Number of true positive hits 103 in 103 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 31
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 76.87 %

Comments [info]

Taxonomic range [info] Eukaryotes, Eukaryotic viruses
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
103 sequences

AGE1_CAEBR  (P0C5E7), AGE1_CAEEL  (Q94125), ATM_ARATH   (Q9M3G7), 
ATM_ASPFU   (Q4WVM7), ATM_ASPOR   (Q2U639), ATM_CANGA   (Q6FRZ9), 
ATM_DEBHA   (Q6BV76), ATM_DROME   (Q5EAK6), ATM_EMENI   (Q5BHE2), 
ATM_EREGS   (Q751J3), ATM_GIBZE   (Q4IB89), ATM_HUMAN   (Q13315), 
ATM_KLULA   (Q6CP76), ATM_MOUSE   (Q62388), ATM_NEUCR   (Q7RZT9), 
ATM_PIG (Q6PQD5), ATM_SCHPO   (O74630), ATM_YARLI   (Q6CAD2), 
ATM_YEAST   (P38110), ATR_CANGA   (Q6FX42), ATR_EREGS   (Q75DB8), 
ATR_KLULA   (Q6CT34), ATR_YEAST   (P38111), MTOR_HUMAN  (P42345), 
MTOR_MOUSE  (Q9JLN9), MTOR_RAT(P42346), P3C2A_HUMAN (O00443), 
P3C2A_MOUSE (Q61194), P3C2A_PONAB (Q5RAY1), P3C2B_HUMAN (O00750), 
P3C2G_HUMAN (O75747), P3C2G_MOUSE (O70167), P3C2G_RAT   (O70173), 
P4KA1_ARATH (Q9SXA1), P4KA2_ARATH (Q9C680), P4KB1_ARATH (Q9FMJ0), 
P4KB2_ARATH (Q0WPX9), PI3K1_DICDI (P54673), PI3K1_SOYBN (P42347), 
PI3K2_DICDI (P54674), PI3K2_SOYBN (P42348), PI3K3_DICDI (P54675), 
PI3K4_DICDI (P54676), PI3K_ARATH  (P42339), PI4KA_BOVIN (O02811), 
PI4KA_HUMAN (P42356), PI4KA_MOUSE (E9Q3L2), PI4KA_RAT   (O08662), 
PI4KB_BOVIN (O02810), PI4KB_CALJA (B0KWC1), PI4KB_DANRE (Q49GP3), 
PI4KB_HUMAN (Q9UBF8), PI4KB_MOUSE (Q8BKC8), PI4KB_OTOGA (B4UT09), 
PI4KB_PAPAN (A9X1A0), PI4KB_PLEMO (B1MTG7), PI4KB_RAT   (O08561), 
PI4KB_RHIFE (B2KI64), PI4KB_SORAR (B3EX61), PI4KB_XENLA (Q6GN16), 
PI4KB_XENTR (A4IID4), PI4K_DICDI  (P54677), PIK1_SCHPO  (Q10366), 
PIK1_YEAST  (P39104), PK3C3_CAEEL (Q9TXI7), PK3C3_HUMAN (Q8NEB9), 
PK3C3_MOUSE (Q6PF93), PK3C3_PIG   (Q5D891), PK3C3_RAT   (O88763), 
PK3C3_XENLA (Q6AZN6), PK3CA_BOVIN (P32871), PK3CA_HUMAN (P42336), 
PK3CA_MOUSE (P42337), PK3CA_RAT   (A0A0G2K344), PK3CB_HUMAN (P42338), 
PK3CB_MOUSE (Q8BTI9), PK3CB_RAT   (Q9Z1L0), PK3CD_HUMAN (O00329), 
PK3CD_MOUSE (O35904), PK3CG_HUMAN (P48736), PK3CG_MOUSE (Q9JHG7), 
PK3CG_PIG   (O02697), PRKDC_CANLF (Q8WN22), PRKDC_CHICK (Q8QGX4), 
PRKDC_HUMAN (P78527), PRKDC_MOUSE (P97313), PRKDC_XENLA (Q9DEI1), 
STT4_ENCCU  (Q8SQY7), STT4_SCHPO  (Q9USR3), STT4_YEAST  (P37297), 
TOR1_SCHPO  (O14356), TOR1_YEAST  (P35169), TOR2_SCHPO  (Q9Y7K2), 
TOR2_YEAST  (P32600), TOR_ARATH   (Q9FR53), TOR_CAEEL   (Q95Q95), 
TOR_DICDI   (Q86C65), TOR_DROME   (Q9VK45), TOR_ORYSJ   (Q0DJS1), 
VPS34_CANAL (A0A1D8PDV7), VPS34_CANAX (Q92213), VPS34_SCHPO (P50520), 
VPS34_YEAST (P22543)
» more

UniProtKB/Swiss-Prot
False negative sequences
31 sequences

LSB6_SCHPO  (Q9UT42), LSB6_YEAST  (P42951), P4K2A_DANRE (Q6PE18), 
P4K2A_HUMAN (Q9BTU6), P4K2A_MOUSE (Q2TBE6), P4K2A_RAT   (Q99M64), 
P4K2A_XENLA (Q08B31), P4K2A_XENTR (Q505I0), P4K2B_CHICK (Q5ZIK0), 
P4K2B_DANRE (Q49GP5), P4K2B_HUMAN (Q8TCG2), P4K2B_MOUSE (Q8CBQ5), 
P4K2B_RAT   (Q5XIL2), P4K2B_XENLA (Q6DCQ8), P4K2B_XENTR (Q28G26), 
P4KG1_ARATH (O22199), P4KG2_ARATH (Q9SGW8), P4KG3_ARATH (Q9FNF8), 
P4KG4_ARATH (Q9ZPY9), P4KG4_ORYSJ (Q6K881), P4KG5_ARATH (Q9C671), 
P4KG6_ARATH (Q8W4R8), P4KG7_ARATH (Q9SI52), P4KG8_ARATH (Q0WMZ6), 
PI4P2_HUMAN (A4QPH2), PIK1A_CANAL (Q9UW24), PIK1_CANAL  (Q9UW20), 
PIKI1_CAEEL (G5EDY0), VPS34_CANGA (Q6FSR7), VPS34_ENCCU (Q8SR56), 
YL615_MIMIV (Q5UR69)
» more

PDB
[Detailed view]
415 PDB

1E7U; 1E7V; 1E8W; 1E8X; 1E8Y; 1E8Z; 1E90; 1HE8; 2A4Z; 2A5U; 2CHW; 2CHX; 2CHZ; 2RD0; 2V4L; 2WXF; 2WXG; 2WXH; 2WXI; 2WXJ; 2WXK; 2WXL; 2WXM; 2WXN; 2WXO; 2WXP; 2WXQ; 2WXR; 2X38; 2Y3A; 3APC; 3APD; 3APF; 3CSF; 3CST; 3DBS; 3DPD; 3ENE; 3HHM; 3HIZ; 3IBE; 3IHY; 3JBZ; 3L08; 3L13; 3L16; 3L17; 3L54; 3LJ3; 3LS8; 3MJW; 3ML8; 3ML9; 3NZS; 3NZU; 3OAW; 3P2B; 3PRE; 3PRZ; 3PS6; 3QAQ; 3QAR; 3QJZ; 3QK0; 3R7Q; 3R7R; 3S2A; 3SD5; 3T8M; 3TJP; 3TL5; 3ZIM; 3ZVV; 3ZW3; 4A55; 4AJW; 4ANU; 4ANV; 4ANW; 4ANX; 4AOF; 4BFR; 4D0L; 4D0M; 4DK5; 4EZJ; 4EZK; 4EZL; 4F1S; 4FA6; 4FAD; 4FHJ; 4FHK; 4FJY; 4FJZ; 4FLH; 4FUL; 4G11; 4GB9; 4HLE; 4HVB; 4J6I; 4JPS; 4JSN; 4JSP; 4JSV; 4JSX; 4JT5; 4JT6; 4KZ0; 4KZC; 4L1B; 4L23; 4L2Y; 4OVU; 4OVV; 4OYS; 4PH4; 4PS3; 4PS7; 4PS8; 4TUU; 4TV3; 4URK; 4UWF; 4UWG; 4UWH; 4UWK; 4UWL; 4V0I; 4WAE; 4WAF; 4WAG; 4WWN; 4WWO; 4WWP; 4XE0; 4XX5; 4XZ4; 4YKN; 4ZOP; 5AE8; 5AE9; 5ANL; 5C46; 5C4G; 5DFZ; 5DXH; 5DXT; 5DXU; 5EDS; 5ENN; 5EUQ; 5FBL; 5FBQ; 5FBR; 5FBV; 5FBW; 5FI4; 5FLC; 5G2N; 5G55; 5H64; 5I4U; 5I6U; 5IS5; 5ITD; 5JHA; 5JHB; 5KAE; 5KC2; 5L72; 5LUQ; 5M6U; 5NCY; 5NCZ; 5NGB; 5NP0; 5NP1; 5O83; 5OQ4; 5SW8; 5SWG; 5SWO; 5SWP; 5SWR; 5SWT; 5SX8; 5SX9; 5SXA; 5SXB; 5SXC; 5SXD; 5SXE; 5SXF; 5SXI; 5SXJ; 5SXK; 5T23; 5T27; 5T28; 5T2B; 5T2D; 5T2G; 5T2I; 5T2L; 5T2M; 5T7F; 5T8F; 5T8I; 5UBR; 5UBT; 5UK8; 5UKJ; 5UL1; 5VLR; 5W1R; 5WBU; 5WBY; 5X6O; 5XGH; 5XGI; 5XGJ; 5Y3R; 5ZCS; 6AUD; 6BCU; 6BCX; 6BQ1; 6C1S; 6DGT; 6EMK; 6EYZ; 6EZ6; 6FH5; 6G6W; 6GL3; 6GQ7; 6GVF; 6GVG; 6GVH; 6GVI; 6GY0; 6HI9; 6I3U; 6JXA; 6JXC; 6K9K; 6K9L; 6MUL; 6MUM; 6NCT; 6OAC; 6OCO; 6OCU; 6PYR; 6PYS; 6PYU; 6S8F; 6SB0; 6SB2; 6T3B; 6T3C; 6XRL; 6XRM; 6XRN; 6YKG; 6Z2W; 6Z2X; 6Z3A; 6ZFP; 6ZH2; 6ZH4; 6ZH6; 6ZH8; 6ZHA; 6ZHE; 6ZWM; 6ZWO; 7BI2; 7BI4; 7BI6; 7BI9; 7BL1; 7JIS; 7JIU; 7JWE; 7JWZ; 7JX0; 7K0Y; 7K10; 7K11; 7K19; 7K1B; 7K1J; 7K1K; 7K1N; 7K6M; 7K6N; 7K6O; 7K71; 7KKE; 7LM2; 7LQ1; 7LT3; 7MEZ; 7MLK; 7MYN; 7MYO; 7NFC; 7NFE; 7NI4; 7NI5; 7NI6; 7OTM; 7OTP; 7OTV; 7OTW; 7OTY; 7OWG; 7PE7; 7PE8; 7PE9; 7PEA; 7PEB; 7PEC; 7PG5; 7PG6; 7PQH; 7R9V; 7R9Y; 7RSJ; 7RSP; 7RSV; 7SGL; 7SIC; 7SID; 7SU3; 7SUD; 7TYR; 7TZ7; 7TZO; 7UXC; 7UXH; 7WZR; 7WZW; 7Z61; 7Z74; 7Z75; 7Z87; 7Z88; 8A9I; 8AJ8; 8AM0; 8BCY; 8BFU; 8BH3; 8BHV; 8BHY; 8BOT; 8DCP; 8DCX; 8DD4; 8DD8; 8DP0; 8ERA; 8EXL; 8EXO; 8EXU; 8EXV; 8EZ9; 8EZA; 8EZB; 8GUA; 8GUB; 8GUD; 8ILR; 8ILS; 8ILV; 8OW2; 8OXM; 8OXO; 8OXP; 8OXQ; 8Q6F; 8Q6G; 8Q6H; 8RXR; 8S3R; 8SBC; 8SBJ; 8SC8; 8SOR; 8TDU; 8TGD; 8TS7; 8TS8; 8TS9; 8TSA; 8TSB; 8TSC; 8TSD; 8TU6; 8TWY; 8V8H; 8V8I; 8V8J; 8V8U; 8V8V; 8VOF; 8W9A; 8W9B; 9C82; 9F44; 9F45
» more