Entry: PS01062

General information about the entry
Entry name HMG_COA_LYASE
Accession number PS01062
Entry type PATTERN
Date NOV-1995 (CREATED); NOV-1995 (DATA UPDATE); APR-2013 (INFO UPDATE).
PROSITE Documentation PDOC00813
Associated ProRule PRU10115
Name and characterization of the entry
DescriptionHydroxymethylglutaryl-coenzyme A lyase active site.
Pattern S-V-A-G-L-G-G-C-P-Y.
Numerical results
  • UniProtKB/Swiss-Prot release number: 2013_06, total number of sequence entries in that release: 540261.
  • Total number of hits in UniProtKB/Swiss-Prot: 8 hits in 8 different sequences
  • Number of hits on proteins that are known to belong to the set under consideration: 8 hits in 8 different sequences
  • Number of hits on proteins that could potentially belong to the set under consideration: 0 hits in 0 different sequences
  • Number of false hits (on unrelated proteins): 0 hits in 0 different sequences
  • Number of known missed hits: 5
  • Number of partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences: 0
  • Precision (true hits / (true hits + false positives)): 100.00 %
  • Recall (true hits / (true hits + false negatives)): 61.54 %
Comments
  • Taxonomic range: Eukaryotes, Prokaryotes (Bacteria)
  • Maximum known number of repetitions of the pattern in a single protein: 1
  • `Interesting' site in the pattern: 8,active_site
  • VERSION: 1
Cross-references
UniProtKB/Swiss-Prot True positive hits:
HMGCL_BOVIN (Q29448), HMGCL_CHICK (P35915), HMGCL_HUMAN (P35914), 
HMGCL_MACFA (Q8HXZ6), HMGCL_MOUSE (P38060), HMGCL_PONAB (Q5R9E1), 
HMGCL_PSEMV (P13703), HMGCL_RAT   (P97519)
False negative hits (sequences which belong to the set under consideration, but which have not been picked up by the pattern or profile):
HMGC2_DANRE (A8WG57), HMGC2_HUMAN (Q8TB92), HMGC2_MOUSE (Q8JZS7), 
HMGC2_RAT   (D4A5C3), HMGCL_BACSU (O34873)
Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:

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PDB
[Detailed view]		 2CW6; 3MP3; 3MP4; 3MP5;

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