Entry: PS01192

General information about the entry

Entry name [info] HMG_COA_REDUCTASE_3
Accession [info] PS01192
Entry type [info] PATTERN
Date [info] NOV-1997 (CREATED); NOV-1997 (DATA UPDATE); JUN-2015 (INFO UPDATE).
PROSITE Doc. [info] PDOC00064
Associated ProRule [info] PRU10003

Name and characterization of the entry

Description [info] Hydroxymethylglutaryl-coenzyme A reductases signature 3.
Pattern [info]
A-[LIVM]-x-[STAN]-x(2)-[LI]-x-[KRNQ]-[GSA]-H-[LM]-x-[FYLH].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2015_08 which contains 320'201 sequence entries.


Total number of hits 46 in 46 different sequences
Number of true positive hits 46 in 46 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 10
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 82.14 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] active_site at position 10
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
46 sequences

HMDH1_ARATH (P14891), HMDH1_DICDI (P34135), HMDH1_GOSHI (O64966), 
HMDH1_HEVBR (P29057), HMDH1_ORYSI (A2X8W3), HMDH1_ORYSJ (Q0DY59), 
HMDH1_SOLTU (P48020), HMDH1_YEAST (P12683), HMDH2_ARATH (P43256), 
HMDH2_CAPAN (Q9XEL8), HMDH2_DICDI (P34136), HMDH2_GOSHI (O64967), 
HMDH2_HEVBR (P29058), HMDH2_SOLLC (P48022), HMDH2_SOLTU (Q41437), 
HMDH2_YEAST (P12684), HMDH3_HEVBR (Q00583), HMDH3_ORYSJ (Q9XHL5), 
HMDH3_SOLTU (Q41438), HMDH_AGRIP  (O76819), HMDH_ARCFU  (O28538), 
HMDH_ASPTE  (Q9Y7D2), HMDH_ASPTN  (Q0C8L9), HMDH_BLAGE  (P54960), 
HMDH_BOVIN  (A7Z064), HMDH_CAMAC  (P48021), HMDH_CATRO  (Q03163), 
HMDH_CRIGR  (P00347), HMDH_CYBJA  (O74164), HMDH_DROME  (P14773), 
HMDH_GIBF5  (S0DQM8), HMDH_GIBFU  (P0CT44), HMDH_HUMAN  (P04035), 
HMDH_MAIZE  (O24594), HMDH_MESAU  (P09610), HMDH_MOUSE  (Q01237), 
HMDH_NICSY  (Q01559), HMDH_PHYB8  (Q12649), HMDH_PIG    (Q1W675), 
HMDH_PONAB  (Q5R6N3), HMDH_RABIT  (Q29512), HMDH_RAT    (P51639), 
HMDH_SCHMA  (P16237), HMDH_STRPU  (P16393), HMDH_XENLA  (P20715), 
MVAA_PSEMV  (P13702)
» More

UniProtKB/Swiss-Prot
False negative sequences
10 sequences

HMDH_AERPE  (Q9YAS4), HMDH_BORBU  (O51628), HMDH_HALS3  (B0R6J9), 
HMDH_HALVD  (Q59468), HMDH_METJA  (Q58116), HMDH_METTH  (O26662), 
HMDH_PYRAB  (Q9V1R3), HMDH_PYRHO  (O59469), HMDH_SCHPO  (Q10283), 
HMDH_SULSO  (O08424)
» More

PDB
[Detailed view]
4 PDB

1DQA; 1QAX; 1QAY; 4I4B

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