Entry: PS01192

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General information about the entry

Entry name [info] HMG_COA_REDUCTASE_3
Accession [info] PS01192
Entry type [info] PATTERN
Date [info] NOV-1997 (CREATED); NOV-1997 (DATA UPDATE); JUL-2014 (INFO UPDATE).
PROSITE Doc. [info] PDOC00064
Associated ProRule [info] PRU10003

Name and characterization of the entry

Description [info] Hydroxymethylglutaryl-coenzyme A reductases signature 3.
Pattern [info]
A-[LIVM]-x-[STAN]-x(2)-[LI]-x-[KRNQ]-[GSA]-H-[LM]-x-[FYLH].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2014_09 which contains 546'439 sequence entries.


Total number of hits 46 in 46 different sequences
Number of true positive hits 46 in 46 different sequences
Number of 'unknown' hits
Number of false positive hits
Number of false negative sequences 10
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 82.14 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] active_site at position 10
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
46 sequences

HMDH1_ARATH (P14891), HMDH1_DICDI (P34135), HMDH1_GOSHI (O64966), 
HMDH1_HEVBR (P29057), HMDH1_ORYSI (A2X8W3), HMDH1_ORYSJ (Q0DY59), 
HMDH1_SOLTU (P48020), HMDH1_YEAST (P12683), HMDH2_ARATH (P43256), 
HMDH2_CAPAN (Q9XEL8), HMDH2_DICDI (P34136), HMDH2_GOSHI (O64967), 
HMDH2_HEVBR (P29058), HMDH2_SOLLC (P48022), HMDH2_SOLTU (Q41437), 
HMDH2_YEAST (P12684), HMDH3_HEVBR (Q00583), HMDH3_ORYSJ (Q9XHL5), 
HMDH3_SOLTU (Q41438), HMDH_AGRIP  (O76819), HMDH_ARCFU  (O28538), 
HMDH_ASPTE  (Q9Y7D2), HMDH_ASPTN  (Q0C8L9), HMDH_BLAGE  (P54960), 
HMDH_BOVIN  (A7Z064), HMDH_CAMAC  (P48021), HMDH_CATRO  (Q03163), 
HMDH_CRIGR  (P00347), HMDH_CYBJA  (O74164), HMDH_DROME  (P14773), 
HMDH_GIBF5  (S0DQM8), HMDH_GIBFU  (P0CT44), HMDH_HUMAN  (P04035), 
HMDH_MAIZE  (O24594), HMDH_MESAU  (P09610), HMDH_MOUSE  (Q01237), 
HMDH_NICSY  (Q01559), HMDH_PHYB8  (Q12649), HMDH_PIG    (Q1W675), 
HMDH_PONAB  (Q5R6N3), HMDH_RABIT  (Q29512), HMDH_RAT    (P51639), 
HMDH_SCHMA  (P16237), HMDH_STRPU  (P16393), HMDH_XENLA  (P20715), 
MVAA_PSEMV  (P13702)
» More

UniProtKB/Swiss-Prot
False negative sequences
10 sequences

HMDH_AERPE  (Q9YAS4), HMDH_BORBU  (O51628), HMDH_HALS3  (B0R6J9), 
HMDH_HALVD  (Q59468), HMDH_METJA  (Q58116), HMDH_METTH  (O26662), 
HMDH_PYRAB  (Q9V1R3), HMDH_PYRHO  (O59469), HMDH_SCHPO  (Q10283), 
HMDH_SULSO  (O08424)
» More

PDB
[Detailed view]
4 PDB

1DQA; 1QAX; 1QAY; 4I4B

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