Entry: PS01192

General information about the entry
Entry name HMG_COA_REDUCTASE_3
Accession number PS01192
Entry type PATTERN
Date NOV-1997 (CREATED); NOV-1997 (DATA UPDATE); MAR-2013 (INFO UPDATE).
PROSITE Documentation PDOC00064
Associated ProRule PRU10003
Name and characterization of the entry
DescriptionHydroxymethylglutaryl-coenzyme A reductases signature 3.
Pattern A-[LIVM]-x-[STAN]-x(2)-[LI]-x-[KRNQ]-[GSA]-H-[LM]-x-[FYLH].
Numerical results
  • UniProtKB/Swiss-Prot release number: 2013_05, total number of sequence entries in that release: 540052.
  • Total number of hits in UniProtKB/Swiss-Prot: 45 hits in 45 different sequences
  • Number of hits on proteins that are known to belong to the set under consideration: 45 hits in 45 different sequences
  • Number of hits on proteins that could potentially belong to the set under consideration: 0 hits in 0 different sequences
  • Number of false hits (on unrelated proteins): 0 hits in 0 different sequences
  • Number of known missed hits: 9
  • Number of partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences: 0
  • Precision (true hits / (true hits + false positives)): 100.00 %
  • Recall (true hits / (true hits + false negatives)): 83.33 %
Comments
  • Taxonomic range: Archaea, Eukaryotes, Prokaryotes (Bacteria)
  • Maximum known number of repetitions of the pattern in a single protein: 1
  • `Interesting' site in the pattern: 10,active_site
  • VERSION: 1
Cross-references
UniProtKB/Swiss-Prot True positive hits:
HMDH1_ARATH (P14891), HMDH1_DICDI (P34135), HMDH1_GOSHI (O64966), 
HMDH1_HEVBR (P29057), HMDH1_ORYSI (A2X8W3), HMDH1_ORYSJ (Q0DY59), 
HMDH1_SOLTU (P48020), HMDH1_YEAST (P12683), HMDH2_ARATH (P43256), 
HMDH2_CAPAN (Q9XEL8), HMDH2_DICDI (P34136), HMDH2_GOSHI (O64967), 
HMDH2_HEVBR (P29058), HMDH2_SOLLC (P48022), HMDH2_SOLTU (Q41437), 
HMDH2_YEAST (P12684), HMDH3_HEVBR (Q00583), HMDH3_ORYSJ (Q9XHL5), 
HMDH3_SOLTU (Q41438), HMDH_AGRIP  (O76819), HMDH_ARCFU  (O28538), 
HMDH_ASPTE  (Q9Y7D2), HMDH_ASPTN  (Q0C8L9), HMDH_BLAGE  (P54960), 
HMDH_BOVIN  (A7Z064), HMDH_CAMAC  (P48021), HMDH_CATRO  (Q03163), 
HMDH_CRIGR  (P00347), HMDH_CYBJA  (O74164), HMDH_DROME  (P14773), 
HMDH_GIBFU  (Q12577), HMDH_HUMAN  (P04035), HMDH_MAIZE  (O24594), 
HMDH_MESAU  (P09610), HMDH_MOUSE  (Q01237), HMDH_NICSY  (Q01559), 
HMDH_PHYB8  (Q12649), HMDH_PIG    (Q1W675), HMDH_PONAB  (Q5R6N3), 
HMDH_RABIT  (Q29512), HMDH_RAT    (P51639), HMDH_SCHMA  (P16237), 
HMDH_STRPU  (P16393), HMDH_XENLA  (P20715), MVAA_PSEMV  (P13702)
False negative hits (sequences which belong to the set under consideration, but which have not been picked up by the pattern or profile):
HMDH_AERPE  (Q9YAS4), HMDH_BORBU  (O51628), HMDH_HALVD  (Q59468), 
HMDH_METJA  (Q58116), HMDH_METTH  (O26662), HMDH_PYRAB  (Q9V1R3), 
HMDH_PYRHO  (O59469), HMDH_SCHPO  (Q10283), HMDH_SULSO  (O08424)
Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:

[Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format]

Retrieve the sequence logo from the alignment

PDB
[Detailed view]		 1DQA; 1QAX; 1QAY;

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