Entry: PS01209

General information about the entry

Entry name [info] LDLRA_1
Accession [info] PS01209
Entry type [info] PATTERN
Date [info] NOV-1997 (CREATED); APR-2006 (DATA UPDATE); JUN-2015 (INFO UPDATE).
PROSITE Doc. [info] PDOC00929

Name and characterization of the entry

Description [info] LDL-receptor class A (LDLRA) domain signature.
Pattern [info]
C-[VILMA]-x(5,6)-C-[DNH]-x(3)-[DENQHT]-C-x(3,4)-[STADEW]-[DEH]-[DE]-
x(1,5)-C.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2015_08 which contains 320'201 sequence entries.


Total number of hits 710 in 149 different sequences
Number of true positive hits 709 in 148 different sequences
Number of 'unknown' hits 0
Number of false positive hits 1
Number of false negative sequences 10
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 99.86 %
Recall (true positives / (true positives + false negatives)) 98.61 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 31
Site [info] disulfide at position 1
Site [info] disulfide at position 4
Site [info] disulfide at position 8
Site [info] disulfide at position 14
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
148 sequences

AEGP_HUMAN  (Q6UXC1), AEGP_MOUSE  (A2AJA7), AEGP_RAT    (Q63191), 
CD320_BOVIN (A6QNY1), CD320_HUMAN (Q9NPF0), CD320_MOUSE (Q9Z1P5), 
CD320_RAT   (Q5HZW5), CFAI_HUMAN  (P05156), CFAI_MOUSE  (Q61129), 
CFAI_PONAB  (Q5R5A4), CFAI_RAT    (Q9WUW3), CO6_BOVIN   (Q29RU4), 
CO6_HUMAN   (P13671), CO6_PANTR   (P61134), CO6_PONPY   (P61135), 
CO6_RAT     (Q811M5), CO7_BOVIN   (Q29RQ1), CO7_HUMAN   (P10643), 
CO7_PIG     (Q9TUQ3), CO7_PONAB   (Q5RAD0), CO8A_HUMAN  (P07357), 
CO8A_MOUSE  (Q8K182), CO8A_RABIT  (P98136), CO8B_HUMAN  (P07358), 
CO8B_MOUSE  (Q8BH35), CO8B_PAROL  (Q9PVW7), CO8B_RABIT  (P98137), 
CO8B_RAT    (P55314), CO9_BOVIN   (Q3MHN2), CO9_HORSE   (P48770), 
CO9_HUMAN   (P02748), CO9_MOUSE   (P06683), CO9_ONCMY   (P06682), 
CO9_RABIT   (P48747), CO9_RAT     (Q62930), CO9_TAKRU   (P79755), 
CORIN_HUMAN (Q9Y5Q5), CORIN_MOUSE (Q9Z319), CORIN_RAT   (Q80YN4), 
CTX_SEPES   (B2DCR8), ENTK_BOVIN  (P98072), ENTK_HUMAN  (P98073), 
ENTK_MOUSE  (P97435), ENTK_PIG    (P98074), GLBL_LAMSP  (P16222), 
GLBL_TYLHE  (P18207), GLBM_TYLHE  (P18208), GR101_LYMST (P46023), 
IDD_HUMAN   (P98153), IDD_MOUSE   (P98154), LDLR1_XENLA (Q99087), 
LDLR2_XENLA (Q99088), LDLR_CRIGR  (P35950), LDLR_HUMAN  (P01130), 
LDLR_MOUSE  (P35951), LDLR_PIG    (Q28832), LDLR_RABIT  (P20063), 
LDLR_RAT    (P35952), LRAD1_HUMAN (Q5T700), LRAD3_HUMAN (Q86YD5), 
LRAD3_MOUSE (A2AR95), LRAD3_XENTR (A4IHY6), LRAD4_HUMAN (O15165), 
LRAD4_MOUSE (Q8BWJ4), LRP10_HUMAN (Q7Z4F1), LRP10_MOUSE (Q7TQH7), 
LRP11_HUMAN (Q86VZ4), LRP11_MOUSE (Q8CB67), LRP12_HUMAN (Q9Y561), 
LRP12_MACFA (Q9BE74), LRP12_MOUSE (Q8BUJ9), LRP12_PONAB (Q5R662), 
LRP1B_HUMAN (Q9NZR2), LRP1B_MOUSE (Q9JI18), LRP1_CHICK  (P98157), 
LRP1_HUMAN  (Q07954), LRP1_MOUSE  (Q91ZX7), LRP2_HUMAN  (P98164), 
LRP2_MOUSE  (A2ARV4), LRP2_RAT    (P98158), LRP3_HUMAN  (O75074), 
LRP3_RAT    (O88204), LRP4_HUMAN  (O75096), LRP4_MOUSE  (Q8VI56), 
LRP4_RAT    (Q9QYP1), LRP5_HUMAN  (O75197), LRP5_MOUSE  (Q91VN0), 
LRP6_HUMAN  (O75581), LRP6_MOUSE  (O88572), LRP8_CHICK  (Q98931), 
LRP8_HUMAN  (Q14114), LRP8_MOUSE  (Q924X6), LRP_CAEEL   (Q04833), 
MALR1_HUMAN (Q5VYJ5), MFRP_HUMAN  (Q9BY79), MFRP_MOUSE  (Q8K480), 
MLRP1_ACRMI (B3EWZ5), MLRP2_ACRMI (B3EWZ6), NETO1_HUMAN (Q8TDF5), 
NETO1_MOUSE (Q8R4I7), NETO2_HUMAN (Q8NC67), NETO2_MOUSE (Q8BNJ6), 
NETO2_RAT   (C6K2K4), NUDEL_DROME (P98159), PGBM_HUMAN  (P98160), 
PGBM_MOUSE  (Q05793), PROH4_APIME (P85831), RXFP1_HUMAN (Q9HBX9), 
RXFP1_MOUSE (Q6R6I7), RXFP1_PONAB (Q5R5V8), RXFP1_RAT   (Q6R6I6), 
RXFP2_CANFA (Q5XM32), RXFP2_HUMAN (Q8WXD0), RXFP2_MOUSE (Q91ZZ5), 
SORL_CHICK  (Q98930), SORL_HUMAN  (Q92673), SORL_MOUSE  (O88307), 
SORL_RABIT  (Q95209), SPIT1_HUMAN (O43278), SPIT1_MOUSE (Q9R097), 
SSPO_BOVIN  (P98167), SSPO_CHICK  (Q2PC93), SSPO_HUMAN  (A2VEC9), 
SSPO_MOUSE  (Q8CG65), SSPO_RAT    (Q700K0), ST14_BOVIN  (Q0IIH7), 
ST14_HUMAN  (Q9Y5Y6), ST14_MOUSE  (P56677), TMPS2_HUMAN (O15393), 
TMPS2_MOUSE (Q9JIQ8), TMPS3_HUMAN (P57727), TMPS3_MOUSE (Q8K1T0), 
TMPS6_HUMAN (Q8IU80), TMPS6_MOUSE (Q9DBI0), TMPS7_HUMAN (Q7RTY8), 
TMPS7_MOUSE (Q8BIK6), TMPS7_RAT   (P86091), TMPS9_HUMAN (Q7Z410), 
TMPS9_MOUSE (P69525), TMPS9_RAT   (P69526), UNC52_CAEEL (Q06561), 
VGR_SOLIN   (Q6X0I2), VLDLR_CHICK (P98165), VLDLR_HUMAN (P98155), 
VLDLR_MOUSE (P98156), VLDLR_RABIT (P35953), VLDLR_RAT   (P98166), 
YL_DROME    (P98163)
» More

UniProtKB/Swiss-Prot
False negative sequences
10 sequences

ALK_HUMAN   (Q9UM73), ALK_MOUSE   (P97793), PKD1_HUMAN  (P98161), 
PKD1_MOUSE  (O08852), RSVR_COTJA  (P98162), TMPS4_HUMAN (Q9NRS4), 
TMPS4_MOUSE (Q8VCA5), TMPSD_HUMAN (Q9BYE2), TMPSD_MOUSE (Q5U405), 
YL54_CAEEL  (P34434)
» More

UniProtKB/Swiss-Prot
'Partial' sequences
1 sequence

LDLR_BOVIN  (P01131)

		
UniProtKB/Swiss-Prot
False positive sequences
1 sequence

GLU2B_ORYSJ (Q5NBP9)

		
PDB
[Detailed view]
32 PDB

1AJJ; 1CR8; 1D2J; 1D2L; 1F5Y; 1F8Z; 1J8E; 1LDL; 1LDR; 1N7D; 1V9U; 1XFE; 2FCW; 2FYJ; 2FYL; 2I1P; 2JM4; 2KNX; 2KNY; 2KRI; 2LGP; 2M0P; 2M7P; 2M96; 3A7Q; 3DPR; 3M0C; 3OJY; 3P5C; 3T5O; 4A5W; 4E0S
» More

View entry in original PROSITE format
View entry in raw text format (no links)
Direct ScanProsite submission