Entry: PS01209

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General information about the entry

Entry name [info] LDLRA_1
Accession [info] PS01209
Entry type [info] PATTERN
Date [info] NOV-1997 (CREATED); APR-2006 (DATA UPDATE); JUN-2014 (INFO UPDATE).
PROSITE Doc. [info] PDOC00929

Name and characterization of the entry

Description [info] LDL-receptor class A (LDLRA) domain signature.
Pattern [info]
C-[VILMA]-x(5,6)-C-[DNH]-x(3)-[DENQHT]-C-x(3,4)-[STADEW]-[DEH]-[DE]-
x(1,5)-C.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2014_07 which contains 546'000 sequence entries.


Total number of hits 710 in 149 different sequences
Number of true positive hits 709 in 148 different sequences
Number of 'unknown' hits
Number of false positive hits 1
Number of false negative sequences 10
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 99.86 %
Recall (true positives / (true positives + false negatives)) 98.61 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 31
Site [info] disulfide at position 1
Site [info] disulfide at position 4
Site [info] disulfide at position 8
Site [info] disulfide at position 14
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
148 sequences

AEGP_HUMAN  (Q6UXC1), AEGP_MOUSE  (A2AJA7), AEGP_RAT    (Q63191), 
CD320_BOVIN (A6QNY1), CD320_HUMAN (Q9NPF0), CD320_MOUSE (Q9Z1P5), 
CD320_RAT   (Q5HZW5), CFAI_HUMAN  (P05156), CFAI_MOUSE  (Q61129), 
CFAI_PONAB  (Q5R5A4), CFAI_RAT    (Q9WUW3), CO6_BOVIN   (Q29RU4), 
CO6_HUMAN   (P13671), CO6_PANTR   (P61134), CO6_PONPY   (P61135), 
CO6_RAT     (Q811M5), CO7_BOVIN   (Q29RQ1), CO7_HUMAN   (P10643), 
CO7_PIG     (Q9TUQ3), CO7_PONAB   (Q5RAD0), CO8A_HUMAN  (P07357), 
CO8A_MOUSE  (Q8K182), CO8A_RABIT  (P98136), CO8B_HUMAN  (P07358), 
CO8B_MOUSE  (Q8BH35), CO8B_PAROL  (Q9PVW7), CO8B_RABIT  (P98137), 
CO8B_RAT    (P55314), CO9_BOVIN   (Q3MHN2), CO9_HORSE   (P48770), 
CO9_HUMAN   (P02748), CO9_MOUSE   (P06683), CO9_ONCMY   (P06682), 
CO9_RABIT   (P48747), CO9_RAT     (Q62930), CO9_TAKRU   (P79755), 
CORIN_HUMAN (Q9Y5Q5), CORIN_MOUSE (Q9Z319), CORIN_RAT   (Q80YN4), 
CTX_SEPES   (B2DCR8), ENTK_BOVIN  (P98072), ENTK_HUMAN  (P98073), 
ENTK_MOUSE  (P97435), ENTK_PIG    (P98074), GLBL_LAMSP  (P16222), 
GLBL_TYLHE  (P18207), GLBM_TYLHE  (P18208), GR101_LYMST (P46023), 
IDD_HUMAN   (P98153), IDD_MOUSE   (P98154), LDLR1_XENLA (Q99087), 
LDLR2_XENLA (Q99088), LDLR_CRIGR  (P35950), LDLR_HUMAN  (P01130), 
LDLR_MOUSE  (P35951), LDLR_PIG    (Q28832), LDLR_RABIT  (P20063), 
LDLR_RAT    (P35952), LRAD1_HUMAN (Q5T700), LRAD3_HUMAN (Q86YD5), 
LRAD3_MOUSE (A2AR95), LRAD3_XENTR (A4IHY6), LRAD4_HUMAN (O15165), 
LRAD4_MOUSE (Q8BWJ4), LRP10_HUMAN (Q7Z4F1), LRP10_MOUSE (Q7TQH7), 
LRP11_HUMAN (Q86VZ4), LRP11_MOUSE (Q8CB67), LRP12_HUMAN (Q9Y561), 
LRP12_MACFA (Q9BE74), LRP12_MOUSE (Q8BUJ9), LRP12_PONAB (Q5R662), 
LRP1B_HUMAN (Q9NZR2), LRP1B_MOUSE (Q9JI18), LRP1_CHICK  (P98157), 
LRP1_HUMAN  (Q07954), LRP1_MOUSE  (Q91ZX7), LRP2_HUMAN  (P98164), 
LRP2_MOUSE  (A2ARV4), LRP2_RAT    (P98158), LRP3_HUMAN  (O75074), 
LRP3_RAT    (O88204), LRP4_HUMAN  (O75096), LRP4_MOUSE  (Q8VI56), 
LRP4_RAT    (Q9QYP1), LRP5_HUMAN  (O75197), LRP5_MOUSE  (Q91VN0), 
LRP6_HUMAN  (O75581), LRP6_MOUSE  (O88572), LRP8_CHICK  (Q98931), 
LRP8_HUMAN  (Q14114), LRP8_MOUSE  (Q924X6), LRP_CAEEL   (Q04833), 
MALR1_HUMAN (Q5VYJ5), MFRP_HUMAN  (Q9BY79), MFRP_MOUSE  (Q8K480), 
MLRP1_ACRMI (B3EWZ5), MLRP2_ACRMI (B3EWZ6), NETO1_HUMAN (Q8TDF5), 
NETO1_MOUSE (Q8R4I7), NETO2_HUMAN (Q8NC67), NETO2_MOUSE (Q8BNJ6), 
NETO2_RAT   (C6K2K4), NUDEL_DROME (P98159), PGBM_HUMAN  (P98160), 
PGBM_MOUSE  (Q05793), PROH4_APIME (P85831), RXFP1_HUMAN (Q9HBX9), 
RXFP1_MOUSE (Q6R6I7), RXFP1_PONAB (Q5R5V8), RXFP1_RAT   (Q6R6I6), 
RXFP2_CANFA (Q5XM32), RXFP2_HUMAN (Q8WXD0), RXFP2_MOUSE (Q91ZZ5), 
SORL_CHICK  (Q98930), SORL_HUMAN  (Q92673), SORL_MOUSE  (O88307), 
SORL_RABIT  (Q95209), SPIT1_HUMAN (O43278), SPIT1_MOUSE (Q9R097), 
SSPO_BOVIN  (P98167), SSPO_CHICK  (Q2PC93), SSPO_HUMAN  (A2VEC9), 
SSPO_MOUSE  (Q8CG65), SSPO_RAT    (Q700K0), ST14_BOVIN  (Q0IIH7), 
ST14_HUMAN  (Q9Y5Y6), ST14_MOUSE  (P56677), TMPS2_HUMAN (O15393), 
TMPS2_MOUSE (Q9JIQ8), TMPS3_HUMAN (P57727), TMPS3_MOUSE (Q8K1T0), 
TMPS6_HUMAN (Q8IU80), TMPS6_MOUSE (Q9DBI0), TMPS7_HUMAN (Q7RTY8), 
TMPS7_MOUSE (Q8BIK6), TMPS7_RAT   (P86091), TMPS9_HUMAN (Q7Z410), 
TMPS9_MOUSE (P69525), TMPS9_RAT   (P69526), UNC52_CAEEL (Q06561), 
VGR_SOLIN   (Q6X0I2), VLDLR_CHICK (P98165), VLDLR_HUMAN (P98155), 
VLDLR_MOUSE (P98156), VLDLR_RABIT (P35953), VLDLR_RAT   (P98166), 
YL_DROME    (P98163)
» More

UniProtKB/Swiss-Prot
False negative sequences
10 sequences

ALK_HUMAN   (Q9UM73), ALK_MOUSE   (P97793), PKD1_HUMAN  (P98161), 
PKD1_MOUSE  (O08852), RSVR_COTJA  (P98162), TMPS4_HUMAN (Q9NRS4), 
TMPS4_MOUSE (Q8VCA5), TMPSD_HUMAN (Q9BYE2), TMPSD_MOUSE (Q5U405), 
YL54_CAEEL  (P34434)
» More

UniProtKB/Swiss-Prot
'Partial' sequences
1 sequence

LDLR_BOVIN  (P01131)

		
UniProtKB/Swiss-Prot
False positive sequences
1 sequence

GLU2B_ORYSJ (Q5NBP9)

		
PDB
[Detailed view]
31 PDB

1AJJ; 1CR8; 1D2J; 1D2L; 1F5Y; 1F8Z; 1J8E; 1LDL; 1LDR; 1N7D; 1V9U; 1XFE; 2FCW; 2FYJ; 2FYL; 2I1P; 2JM4; 2KNX; 2KNY; 2KRI; 2LGP; 2M0P; 2M7P; 3A7Q; 3DPR; 3M0C; 3OJY; 3P5C; 3T5O; 4A5W; 4E0S
» More

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