Entry: PS01209

General information about the entry
Entry name LDLRA_1
Accession number PS01209
Entry type PATTERN
Date NOV-1997 (CREATED); APR-2006 (DATA UPDATE); MAR-2013 (INFO UPDATE).
PROSITE Documentation PDOC00929
Name and characterization of the entry
DescriptionLDL-receptor class A (LDLRA) domain signature.
Pattern C-[VILMA]-x(5,6)-C-[DNH]-x(3)-[DENQHT]-C-x(3,4)-[STADEW]-[DEH]-[DE]- x(1,5)-C.
Numerical results
  • UniProtKB/Swiss-Prot release number: 2013_05, total number of sequence entries in that release: 540052.
  • Total number of hits in UniProtKB/Swiss-Prot: 691 hits in 146 different sequences
  • Number of hits on proteins that are known to belong to the set under consideration: 691 hits in 146 different sequences
  • Number of hits on proteins that could potentially belong to the set under consideration: 0 hits in 0 different sequences
  • Number of false hits (on unrelated proteins): 0 hits in 0 different sequences
  • Number of known missed hits: 10
  • Number of partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences: 1
  • Precision (true hits / (true hits + false positives)): 100.00 %
  • Recall (true hits / (true hits + false negatives)): 98.57 %
Comments
  • Taxonomic range: Eukaryotes
  • Maximum known number of repetitions of the pattern in a single protein: 31
  • `Interesting' site in the pattern: 1,disulfide
  • `Interesting' site in the pattern: 4,disulfide
  • `Interesting' site in the pattern: 8,disulfide
  • `Interesting' site in the pattern: 14,disulfide
  • VERSION: 2
Cross-references
UniProtKB/Swiss-Prot True positive hits:
AEGP_HUMAN  (Q6UXC1), AEGP_MOUSE  (A2AJA7), AEGP_RAT    (Q63191), 
CD320_BOVIN (A6QNY1), CD320_HUMAN (Q9NPF0), CD320_MOUSE (Q9Z1P5), 
CD320_RAT   (Q5HZW5), CFAI_HUMAN  (P05156), CFAI_MOUSE  (Q61129), 
CFAI_PONAB  (Q5R5A4), CFAI_RAT    (Q9WUW3), CJ112_HUMAN (Q5VYJ5), 
CO6_BOVIN   (Q29RU4), CO6_HUMAN   (P13671), CO6_PANTR   (P61134), 
CO6_PONPY   (P61135), CO6_RAT     (Q811M5), CO7_BOVIN   (Q29RQ1), 
CO7_HUMAN   (P10643), CO7_PIG     (Q9TUQ3), CO7_PONAB   (Q5RAD0), 
CO8A_HUMAN  (P07357), CO8A_MOUSE  (Q8K182), CO8A_RABIT  (P98136), 
CO8B_HUMAN  (P07358), CO8B_MOUSE  (Q8BH35), CO8B_PAROL  (Q9PVW7), 
CO8B_RABIT  (P98137), CO8B_RAT    (P55314), CO9_BOVIN   (Q3MHN2), 
CO9_HORSE   (P48770), CO9_HUMAN   (P02748), CO9_MOUSE   (P06683), 
CO9_ONCMY   (P06682), CO9_RABIT   (P48747), CO9_RAT     (Q62930), 
CO9_TAKRU   (P79755), CORIN_HUMAN (Q9Y5Q5), CORIN_MOUSE (Q9Z319), 
CORIN_RAT   (Q80YN4), CTX_SEPES   (B2DCR8), ENTK_BOVIN  (P98072), 
ENTK_HUMAN  (P98073), ENTK_MOUSE  (P97435), ENTK_PIG    (P98074), 
GLBL_LAMSP  (P16222), GLBL_TYLHE  (P18207), GLBM_TYLHE  (P18208), 
GR101_LYMST (P46023), IDD_HUMAN   (P98153), IDD_MOUSE   (P98154), 
LDLR1_XENLA (Q99087), LDLR2_XENLA (Q99088), LDLR_CRIGR  (P35950), 
LDLR_HUMAN  (P01130), LDLR_MOUSE  (P35951), LDLR_PIG    (Q28832), 
LDLR_RABIT  (P20063), LDLR_RAT    (P35952), LRAD1_HUMAN (Q5T700), 
LRAD3_HUMAN (Q86YD5), LRAD3_MOUSE (A2AR95), LRAD3_XENTR (A4IHY6), 
LRAD4_HUMAN (O15165), LRAD4_MOUSE (Q8BWJ4), LRP10_HUMAN (Q7Z4F1), 
LRP10_MOUSE (Q7TQH7), LRP11_HUMAN (Q86VZ4), LRP11_MOUSE (Q8CB67), 
LRP12_HUMAN (Q9Y561), LRP12_MACFA (Q9BE74), LRP12_MOUSE (Q8BUJ9), 
LRP12_PONAB (Q5R662), LRP1B_HUMAN (Q9NZR2), LRP1B_MOUSE (Q9JI18), 
LRP1_CHICK  (P98157), LRP1_HUMAN  (Q07954), LRP1_MOUSE  (Q91ZX7), 
LRP2_HUMAN  (P98164), LRP2_MOUSE  (A2ARV4), LRP2_RAT    (P98158), 
LRP3_HUMAN  (O75074), LRP3_RAT    (O88204), LRP4_HUMAN  (O75096), 
LRP4_MOUSE  (Q8VI56), LRP4_RAT    (Q9QYP1), LRP5_HUMAN  (O75197), 
LRP5_MOUSE  (Q91VN0), LRP6_HUMAN  (O75581), LRP6_MOUSE  (O88572), 
LRP8_CHICK  (Q98931), LRP8_HUMAN  (Q14114), LRP8_MOUSE  (Q924X6), 
LRP_CAEEL   (Q04833), MFRP_HUMAN  (Q9BY79), MFRP_MOUSE  (Q8K480), 
NETO1_HUMAN (Q8TDF5), NETO1_MOUSE (Q8R4I7), NETO2_HUMAN (Q8NC67), 
NETO2_MOUSE (Q8BNJ6), NETO2_RAT   (C6K2K4), NUDEL_DROME (P98159), 
PGBM_HUMAN  (P98160), PGBM_MOUSE  (Q05793), PROH4_APIME (P85831), 
RXFP1_HUMAN (Q9HBX9), RXFP1_MOUSE (Q6R6I7), RXFP1_PONAB (Q5R5V8), 
RXFP1_RAT   (Q6R6I6), RXFP2_CANFA (Q5XM32), RXFP2_HUMAN (Q8WXD0), 
RXFP2_MOUSE (Q91ZZ5), SORL_CHICK  (Q98930), SORL_HUMAN  (Q92673), 
SORL_MOUSE  (O88307), SORL_RABIT  (Q95209), SPIT1_HUMAN (O43278), 
SPIT1_MOUSE (Q9R097), SSPO_BOVIN  (P98167), SSPO_CHICK  (Q2PC93), 
SSPO_HUMAN  (A2VEC9), SSPO_MOUSE  (Q8CG65), SSPO_RAT    (Q700K0), 
ST14_BOVIN  (Q0IIH7), ST14_HUMAN  (Q9Y5Y6), ST14_MOUSE  (P56677), 
TMPS2_HUMAN (O15393), TMPS2_MOUSE (Q9JIQ8), TMPS3_HUMAN (P57727), 
TMPS3_MOUSE (Q8K1T0), TMPS6_HUMAN (Q8IU80), TMPS6_MOUSE (Q9DBI0), 
TMPS7_HUMAN (Q7RTY8), TMPS7_MOUSE (Q8BIK6), TMPS7_RAT   (P86091), 
TMPS9_HUMAN (Q7Z410), TMPS9_MOUSE (P69525), TMPS9_RAT   (P69526), 
UNC52_CAEEL (Q06561), VGR_SOLIN   (Q6X0I2), VLDLR_CHICK (P98165), 
VLDLR_HUMAN (P98155), VLDLR_MOUSE (P98156), VLDLR_RABIT (P35953), 
VLDLR_RAT   (P98166), YL_DROME    (P98163)
False negative hits (sequences which belong to the set under consideration, but which have not been picked up by the pattern or profile):
ALK_HUMAN   (Q9UM73), ALK_MOUSE   (P97793), PKD1_HUMAN  (P98161), 
PKD1_MOUSE  (O08852), RSVR_COTJA  (P98162), TMPS4_HUMAN (Q9NRS4), 
TMPS4_MOUSE (Q8VCA5), TMPSD_HUMAN (Q9BYE2), TMPSD_MOUSE (Q5U405), 
YL54_CAEEL  (P34434)
`Potential' hits (partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences):
LDLR_BOVIN  (P01131)
Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:

[Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format]

Retrieve the sequence logo from the alignment

PDB
[Detailed view]
1AJJ; 1CR8; 1D2J; 1D2L; 1F5Y; 1F8Z; 1J8E; 1LDL; 1LDR; 1N7D; 1V9U; 1XFE; 2FCW; 2FYJ; 2FYL; 2I1P; 2JM4; 2KNX; 2KNY; 2KRI; 2LGP; 2M0P; 3A7Q; 3DPR; 3M0C; 3OJY; 3P5C; 3T5O; 4A5W; 4E0S;

View entry in original PROSITE format
View entry in raw text format (no links)
Direct ScanProsite submission


If you would like to retrieve all the Swiss-Prot entries referenced in the DR lines of this entry (with the exception of false positive hits) , you can enter a file name. These entries will then be saved to a file under this name. (Please note that this temporary file will only be kept for 1 week.)

File name:

Format: Swiss-Prot Fasta

or