PROSITE entry PS01209
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Direct ScanProsite submission
General information about the entry
| Entry name [info] | LDLRA_1 |
| Accession [info] | PS01209 |
| Entry type [info] | PATTERN |
| Date [info] |
01-NOV-1997 CREATED;
01-APR-2006 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC00929 |
Name and characterization of the entry
| Description [info] | LDL-receptor class A (LDLRA) domain signature. |
| Pattern [info] |
C-[VILMA]-x(5,6)-C-[DNH]-x(3)-[DENQHT]-C-x(3,4)-[STADEW]-[DEH]-[DE]- x(1,5)-C. |
Numerical results [info]
| Total number of hits | 826 in 164 different sequences |
| Number of true positive hits | 825 in 163 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 1 |
| Number of false negative sequences | 15 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 99.88 % |
| Recall (true positives / (true positives + false negatives)) | 98.21 % |
Comments [info]
| Taxonomic range [info] | Eukaryotes |
| Maximum number of repetitions [info] | 31 |
| Site [info] | disulfide at position 1 |
| Site [info] | disulfide at position 4 |
| Site [info] | disulfide at position 8 |
| Site [info] | disulfide at position 14 |
| Version [info] | 2 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
163 sequences
AEGP_HUMAN (Q6UXC1), AEGP_MOUSE (A2AJA7), AEGP_RAT(Q63191), CD320_BOVIN (A6QNY1), CD320_HUMAN (Q9NPF0), CD320_MOUSE (Q9Z1P5), CD320_RAT (Q5HZW5), CDA1_BOMMO (H9J9M0), CFAI_HUMAN (P05156), CFAI_MOUSE (Q61129), CFAI_PONAB (Q5R5A4), CFAI_RAT(Q9WUW3), CO6_BOVIN (Q29RU4), CO6_HUMAN (P13671), CO6_PANTR (P61134), CO6_PONPY (P61135), CO6_RAT (Q811M5), CO7_BOVIN (Q29RQ1), CO7_HUMAN (P10643), CO7_PIG (Q9TUQ3), CO7_PONAB (Q5RAD0), CO8A_HUMAN (P07357), CO8A_MOUSE (Q8K182), CO8A_RABIT (P98136), CO8B_HUMAN (P07358), CO8B_MOUSE (Q8BH35), CO8B_PAROL (Q9PVW7), CO8B_RABIT (P98137), CO8B_RAT(P55314), CO9_BOVIN (Q3MHN2), CO9_HORSE (P48770), CO9_HUMAN (P02748), CO9_MOUSE (P06683), CO9_ONCMY (P06682), CO9_RABIT (P48747), CO9_RAT (Q62930), CO9_TAKRU (P79755), CORIN_HUMAN (Q9Y5Q5), CORIN_MOUSE (Q9Z319), CORIN_RAT (Q80YN4), CPROH_CONVC (A0A0F7YYX3), CTX_SEPES (B2DCR8), EGG1_CAEBR (A8X765), EGG1_CAEEL (Q09967), EGG1_CAERE (E3LYX0), EGG2_CAEEL (Q21629), ENTK_BOVIN (P98072), ENTK_HUMAN (P98073), ENTK_MOUSE (P97435), ENTK_PIG(P98074), GLBL_LAMSP (P16222), GLBL_TYLHE (P18207), GLBM_TYLHE (P18208), GR101_LYMST (P46023), IDD_HUMAN (P98153), IDD_MOUSE (P98154), LDLR1_XENLA (Q99087), LDLR2_XENLA (Q99088), LDLR_BOVIN (P01131), LDLR_CRIGR (P35950), LDLR_HUMAN (P01130), LDLR_MOUSE (P35951), LDLR_PIG(Q28832), LDLR_RABIT (P20063), LDLR_RAT(P35952), LRAD1_HUMAN (Q5T700), LRAD3_HUMAN (Q86YD5), LRAD3_MOUSE (A2AR95), LRAD3_XENTR (A4IHY6), LRAD4_HUMAN (O15165), LRAD4_MOUSE (Q8BWJ4), LRP10_HUMAN (Q7Z4F1), LRP10_MOUSE (Q7TQH7), LRP11_HUMAN (Q86VZ4), LRP11_MOUSE (Q8CB67), LRP12_HUMAN (Q9Y561), LRP12_MACFA (Q9BE74), LRP12_MOUSE (Q8BUJ9), LRP12_PONAB (Q5R662), LRP1B_HUMAN (Q9NZR2), LRP1B_MOUSE (Q9JI18), LRP1_CHICK (P98157), LRP1_HUMAN (Q07954), LRP1_MOUSE (Q91ZX7), LRP1_RAT(G3V928), LRP2_HUMAN (P98164), LRP2_MOUSE (A2ARV4), LRP2_PIG(C0HL13), LRP2_RAT(P98158), LRP3_HUMAN (O75074), LRP3_RAT(O88204), LRP4_HUMAN (O75096), LRP4_MOUSE (Q8VI56), LRP4_RAT(Q9QYP1), LRP5_HUMAN (O75197), LRP5_MOUSE (Q91VN0), LRP6_HUMAN (O75581), LRP6_MOUSE (O88572), LRP8_CHICK (Q98931), LRP8_HUMAN (Q14114), LRP8_MOUSE (Q924X6), LRP_CAEEL (Q04833), LTK_DANRE (F1QVU0), MALR1_HUMAN (Q5VYJ5), MALR1_MOUSE (A2AJX4), MFRP_HUMAN (Q9BY79), MFRP_MOUSE (Q8K480), MLRP1_ACRMI (B3EWZ5), MLRP2_ACRMI (B3EWZ6), MODSP_DROME (Q9VER6), NETO1_HUMAN (Q8TDF5), NETO1_MOUSE (Q8R4I7), NETO2_HUMAN (Q8NC67), NETO2_MOUSE (Q8BNJ6), NETO2_RAT (C6K2K4), NUDEL_DROME (P98159), PGBM_HUMAN (P98160), PGBM_MOUSE (Q05793), PROH4_APIME (P85831), PROH4_CAMFO (E2AX35), RXFP1_HUMAN (Q9HBX9), RXFP1_MOUSE (Q6R6I7), RXFP1_PONAB (Q5R5V8), RXFP1_RAT (Q6R6I6), RXFP2_CANLF (Q5XM32), RXFP2_HUMAN (Q8WXD0), RXFP2_MOUSE (Q91ZZ5), SORL_CHICK (Q98930), SORL_HUMAN (Q92673), SORL_MOUSE (O88307), SORL_RABIT (Q95209), SORL_RAT(P0DSP1), SPIT1_HUMAN (O43278), SPIT1_MOUSE (Q9R097), SSPO_BOVIN (P98167), SSPO_CHICK (Q2PC93), SSPO_HUMAN (A2VEC9), SSPO_MOUSE (Q8CG65), SSPO_RAT(Q700K0), ST14_BOVIN (Q0IIH7), ST14_HUMAN (Q9Y5Y6), ST14_MOUSE (P56677), SVH1_CAEEL (Q17800), TMPS2_HUMAN (O15393), TMPS2_MOUSE (Q9JIQ8), TMPS3_HUMAN (P57727), TMPS3_MOUSE (Q8K1T0), TMPS6_HUMAN (Q8IU80), TMPS6_MOUSE (Q9DBI0), TMPS7_HUMAN (Q7RTY8), TMPS7_MOUSE (Q8BIK6), TMPS7_RAT (P86091), TMPS9_HUMAN (Q7Z410), TMPS9_MOUSE (P69525), TMPS9_RAT (P69526), UNC52_CAEEL (Q06561), VGR_SOLIN (Q6X0I2), VLDLR_CHICK (P98165), VLDLR_HUMAN (P98155), VLDLR_MOUSE (P98156), VLDLR_RABIT (P35953), VLDLR_RAT (P98166), YL_DROME(P98163)» more
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| UniProtKB/Swiss-Prot False negative sequences |
15 sequences
ALK_HUMAN (Q9UM73), ALK_MOUSE (P97793), GLU2B_BOVIN (Q28034), GLU2B_HUMAN (P14314), GLU2B_MOUSE (O08795), MIG13_CAEEL (G5EF33), PKD1_HUMAN (P98161), PKD1_MOUSE (O08852), RSVR_COTJA (P98162), SCD2_CAEEL (O76411), TMPS4_HUMAN (Q9NRS4), TMPS4_MOUSE (Q8VCA5), TMPSD_HUMAN (Q9BYE2), TMPSD_MOUSE (Q5U405), YL54_CAEEL (P34434)» more |
| UniProtKB/Swiss-Prot False positive sequences |
1 sequence
MYCB2_DANRE (F1RD40) |
| PDB [Detailed view] |
116 PDB
1AJJ; 1CR8; 1D2J; 1D2L; 1F5Y; 1F8Z; 1J8E; 1LDL; 1LDR; 1N7D; 1V9U; 1XFE; 2FCW; 2FYJ; 2FYL; 2I1P; 2JM4; 2KNX; 2KNY; 2KRI; 2LGP; 2M0P; 2M7P; 2M96; 2XRC; 3A7Q; 3DPR; 3M0C; 3OJY; 3P5C; 3T5O; 4A5W; 4E0S; 4ZRP; 4ZRQ; 5B4X; 5B4Y; 5FMW; 5H7V; 5O32; 5OY9; 5OYL; 6BYV; 6CXO; 6DLW; 6H03; 6H04; 7F56; 7F57; 7F59; 7F5A; 7F5B; 7FFF; 7FFL; 7FFN; 7MEQ; 7N1H; 7NYC; 7NYD; 7QBD; 7QBE; 7QBF; 7QBG; 7TMW; 7WQX; 7XYD; 7Y0E; 7Y0F; 8B0F; 8B0G; 8B0H; 8DE6; 8EM4; 8EM7; 8HD8; 8IHP; 8JHZ; 8JI0; 8JUT; 8JUU; 8JX8; 8JX9; 8JXA; 8JXB; 8JXC; 8JXD; 8JXE; 8JXF; 8JXG; 8JXH; 8JXI; 8JXJ; 8S0L; 8S0M; 8S0N; 8S9P; 8UA4; 8UA8; 8UFB; 8UFC; 8VGT; 8XI4; 8XI5; 8Y1D; 8Y1E; 8Y7X; 8Y7Y; 8Y87; 8Y88; 8Y89; 8Y8A; 8Y8B; 8YOY; 8YQQ; 8YS2; 8YS4 » more |