Entry: PS01209

General information about the entry

Entry name [info] LDLRA_1
Accession [info] PS01209
Entry type [info] PATTERN
Date [info] NOV-1997 (CREATED); APR-2006 (DATA UPDATE); JUN-2016 (INFO UPDATE).
PROSITE Doc. [info] PDOC00929

Name and characterization of the entry

Description [info] LDL-receptor class A (LDLRA) domain signature.
Pattern [info]
C-[VILMA]-x(5,6)-C-[DNH]-x(3)-[DENQHT]-C-x(3,4)-[STADEW]-[DEH]-[DE]-
x(1,5)-C.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2016_08 which contains 551'987 sequence entries.


Total number of hits 717 in 151 different sequences
Number of true positive hits 716 in 150 different sequences
Number of 'unknown' hits 0
Number of false positive hits 1
Number of false negative sequences 11
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 99.86 %
Recall (true positives / (true positives + false negatives)) 98.49 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 31
Site [info] disulfide at position 1
Site [info] disulfide at position 4
Site [info] disulfide at position 8
Site [info] disulfide at position 14
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
150 sequences

AEGP_HUMAN  (Q6UXC1    ), AEGP_MOUSE  (A2AJA7    ), AEGP_RAT    (Q63191    ), 
CD320_BOVIN (A6QNY1    ), CD320_HUMAN (Q9NPF0    ), CD320_MOUSE (Q9Z1P5    ), 
CD320_RAT   (Q5HZW5    ), CFAI_HUMAN  (P05156    ), CFAI_MOUSE  (Q61129    ), 
CFAI_PONAB  (Q5R5A4    ), CFAI_RAT    (Q9WUW3    ), CO6_BOVIN   (Q29RU4    ), 
CO6_HUMAN   (P13671    ), CO6_PANTR   (P61134    ), CO6_PONPY   (P61135    ), 
CO6_RAT     (Q811M5    ), CO7_BOVIN   (Q29RQ1    ), CO7_HUMAN   (P10643    ), 
CO7_PIG     (Q9TUQ3    ), CO7_PONAB   (Q5RAD0    ), CO8A_HUMAN  (P07357    ), 
CO8A_MOUSE  (Q8K182    ), CO8A_RABIT  (P98136    ), CO8B_HUMAN  (P07358    ), 
CO8B_MOUSE  (Q8BH35    ), CO8B_PAROL  (Q9PVW7    ), CO8B_RABIT  (P98137    ), 
CO8B_RAT    (P55314    ), CO9_BOVIN   (Q3MHN2    ), CO9_HORSE   (P48770    ), 
CO9_HUMAN   (P02748    ), CO9_MOUSE   (P06683    ), CO9_ONCMY   (P06682    ), 
CO9_RABIT   (P48747    ), CO9_RAT     (Q62930    ), CO9_TAKRU   (P79755    ), 
CORIN_HUMAN (Q9Y5Q5    ), CORIN_MOUSE (Q9Z319    ), CORIN_RAT   (Q80YN4    ), 
CTX_SEPES   (B2DCR8    ), ENTK_BOVIN  (P98072    ), ENTK_HUMAN  (P98073    ), 
ENTK_MOUSE  (P97435    ), ENTK_PIG    (P98074    ), GLBL_LAMSP  (P16222    ), 
GLBL_TYLHE  (P18207    ), GLBM_TYLHE  (P18208    ), GR101_LYMST (P46023    ), 
IDD_HUMAN   (P98153    ), IDD_MOUSE   (P98154    ), LDLR1_XENLA (Q99087    ), 
LDLR2_XENLA (Q99088    ), LDLR_CRIGR  (P35950    ), LDLR_HUMAN  (P01130    ), 
LDLR_MOUSE  (P35951    ), LDLR_PIG    (Q28832    ), LDLR_RABIT  (P20063    ), 
LDLR_RAT    (P35952    ), LRAD1_HUMAN (Q5T700    ), LRAD3_HUMAN (Q86YD5    ), 
LRAD3_MOUSE (A2AR95    ), LRAD3_XENTR (A4IHY6    ), LRAD4_HUMAN (O15165    ), 
LRAD4_MOUSE (Q8BWJ4    ), LRP10_HUMAN (Q7Z4F1    ), LRP10_MOUSE (Q7TQH7    ), 
LRP11_HUMAN (Q86VZ4    ), LRP11_MOUSE (Q8CB67    ), LRP12_HUMAN (Q9Y561    ), 
LRP12_MACFA (Q9BE74    ), LRP12_MOUSE (Q8BUJ9    ), LRP12_PONAB (Q5R662    ), 
LRP1B_HUMAN (Q9NZR2    ), LRP1B_MOUSE (Q9JI18    ), LRP1_CHICK  (P98157    ), 
LRP1_HUMAN  (Q07954    ), LRP1_MOUSE  (Q91ZX7    ), LRP2_HUMAN  (P98164    ), 
LRP2_MOUSE  (A2ARV4    ), LRP2_RAT    (P98158    ), LRP3_HUMAN  (O75074    ), 
LRP3_RAT    (O88204    ), LRP4_HUMAN  (O75096    ), LRP4_MOUSE  (Q8VI56    ), 
LRP4_RAT    (Q9QYP1    ), LRP5_HUMAN  (O75197    ), LRP5_MOUSE  (Q91VN0    ), 
LRP6_HUMAN  (O75581    ), LRP6_MOUSE  (O88572    ), LRP8_CHICK  (Q98931    ), 
LRP8_HUMAN  (Q14114    ), LRP8_MOUSE  (Q924X6    ), LRP_CAEEL   (Q04833    ), 
MALR1_HUMAN (Q5VYJ5    ), MALR1_MOUSE (A2AJX4    ), MFRP_HUMAN  (Q9BY79    ), 
MFRP_MOUSE  (Q8K480    ), MLRP1_ACRMI (B3EWZ5    ), MLRP2_ACRMI (B3EWZ6    ), 
NETO1_HUMAN (Q8TDF5    ), NETO1_MOUSE (Q8R4I7    ), NETO2_HUMAN (Q8NC67    ), 
NETO2_MOUSE (Q8BNJ6    ), NETO2_RAT   (C6K2K4    ), NUDEL_DROME (P98159    ), 
PGBM_HUMAN  (P98160    ), PGBM_MOUSE  (Q05793    ), PROH4_APIME (P85831    ), 
PROH4_CAMFO (E2AX35    ), RXFP1_HUMAN (Q9HBX9    ), RXFP1_MOUSE (Q6R6I7    ), 
RXFP1_PONAB (Q5R5V8    ), RXFP1_RAT   (Q6R6I6    ), RXFP2_CANLF (Q5XM32    ), 
RXFP2_HUMAN (Q8WXD0    ), RXFP2_MOUSE (Q91ZZ5    ), SORL_CHICK  (Q98930    ), 
SORL_HUMAN  (Q92673    ), SORL_MOUSE  (O88307    ), SORL_RABIT  (Q95209    ), 
SPIT1_HUMAN (O43278    ), SPIT1_MOUSE (Q9R097    ), SSPO_BOVIN  (P98167    ), 
SSPO_CHICK  (Q2PC93    ), SSPO_HUMAN  (A2VEC9    ), SSPO_MOUSE  (Q8CG65    ), 
SSPO_RAT    (Q700K0    ), ST14_BOVIN  (Q0IIH7    ), ST14_HUMAN  (Q9Y5Y6    ), 
ST14_MOUSE  (P56677    ), TMPS2_HUMAN (O15393    ), TMPS2_MOUSE (Q9JIQ8    ), 
TMPS3_HUMAN (P57727    ), TMPS3_MOUSE (Q8K1T0    ), TMPS6_HUMAN (Q8IU80    ), 
TMPS6_MOUSE (Q9DBI0    ), TMPS7_HUMAN (Q7RTY8    ), TMPS7_MOUSE (Q8BIK6    ), 
TMPS7_RAT   (P86091    ), TMPS9_HUMAN (Q7Z410    ), TMPS9_MOUSE (P69525    ), 
TMPS9_RAT   (P69526    ), UNC52_CAEEL (Q06561    ), VGR_SOLIN   (Q6X0I2    ), 
VLDLR_CHICK (P98165    ), VLDLR_HUMAN (P98155    ), VLDLR_MOUSE (P98156    ), 
VLDLR_RABIT (P35953    ), VLDLR_RAT   (P98166    ), YL_DROME    (P98163    )
» more

UniProtKB/Swiss-Prot
False negative sequences
11 sequences

ALK_HUMAN   (Q9UM73    ), ALK_MOUSE   (P97793    ), PKD1_HUMAN  (P98161    ), 
PKD1_MOUSE  (O08852    ), RSVR_COTJA  (P98162    ), SCD2_CAEEL  (O76411    ), 
TMPS4_HUMAN (Q9NRS4    ), TMPS4_MOUSE (Q8VCA5    ), TMPSD_HUMAN (Q9BYE2    ), 
TMPSD_MOUSE (Q5U405    ), YL54_CAEEL  (P34434    )
» more

UniProtKB/Swiss-Prot
'Partial' sequences
1 sequence

LDLR_BOVIN  (P01131    )

		
UniProtKB/Swiss-Prot
False positive sequences
1 sequence

GLU2B_ORYSJ (Q5NBP9    )

		
PDB
[Detailed view]
33 PDB

1AJJ; 1CR8; 1D2J; 1D2L; 1F5Y; 1F8Z; 1J8E; 1LDL; 1LDR; 1N7D; 1V9U; 1XFE; 2FCW; 2FYJ; 2FYL; 2I1P; 2JM4; 2KNX; 2KNY; 2KRI; 2LGP; 2M0P; 2M7P; 2M96; 3A7Q; 3DPR; 3M0C; 3OJY; 3P5C; 3T5O; 4A5W; 4E0S; 5FMW
» more

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